USPTO Art Unit 1657 Prosecution Statistics

Art Unit Information

Art Unit: 1657
Group: 1650
Tech Center: 1600
Total Cases: 9,583
Last Active: February 2025

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19059018Zonal and Targeted Methods and Uses for Treating a Post-Traumatic Stress DisorderFebruary 2025June 2025Allow410YesNo
18919965LACTOBACILLUS ACIDOPHILUS GOLDGUT-LA100 HAVING FUNCTIONS OF LIPID LOWERING, BLOOD GLUCOSE LOWERING AND WEIGHT LOSS AND APPLICATION THEREOFOctober 2024June 2025Allow820NoNo
18915656EVOLVED INTEGRASES AND METHODS OF USING THE SAME FOR GENOME EDITINGOctober 2024June 2025Allow821YesNo
18815386AUTOBIOTIC COMPOSITIONS AND METHOD FOR PROMOTING HEALTHY GUT MICROBIOMEAugust 2024June 2025Allow920NoNo
18785008GRANULE FOR DETECTING OCCULT BLOOD IN PET URINE AND METHOD FOR PREPARING THE SAMEJuly 2024December 2024Allow501YesNo
18735209METHOD FOR SELECTING AEROBIC DENITRIFYING FUNGUS AND METHOD FOR REMEDIATING WATER BODY WITH LOW CARBON-TO-NITROGEN RATIO USING AEROBIC DENITRIFYING FUNGUSJune 2024February 2025Allow811YesNo
18679906COMPOSITIONS AND METHODS FOR OBTAINING ORGANOIDSMay 2024March 2025Allow1010YesNo
18656253Perfusion Culturing Methods and Uses ThereofMay 2024April 2025Allow1110NoNo
18633352Treatment and prevention of neuropathology associated with neurodegenerative diseasesApril 2024March 2025Allow1100YesNo
18631515PROCESS FOR CONTROLLING ORGANIC ACID RATIOS IN A CARBON DIOXIDE BIOCONVERSION PROCESSApril 2024May 2025Allow1310NoNo
18630584METHODS AND KITS FOR PREDICTING INFUSION REACTION RISK AND ANTIBODY-MEDIATED LOSS OF RESPONSE BY MONITORING SERUM URIC ACID DURING PEGYLATED URICASE THERAPYApril 2024August 2024Allow510YesNo
18622012ORGANOTYPIC DRG-PERIPHERAL NERVE CULTURE SYSTEMMarch 2024March 2025Allow1110YesNo
18606318METHOD OF FORMING A MYCOLOGICAL PRODUCTMarch 2024April 2025Allow1310NoNo
18599428PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOFMarch 2024August 2024Allow530YesNo
18596683PEPTIDE BIOMARKER FOR IDENTIFYING HIPPOCAMPUS SPECIES BASED ON PEPTIDOMICS AND APPLICATION THEREOFMarch 2024April 2025Abandon1320NoNo
18595392LARGE-SCALE PRODUCTION OF MYCELIUM-BASED TEXTILES AT MUSHROOM FARM FACILITIESMarch 2024May 2025Allow1410YesNo
18686912Depolymerization of a Polyhydroxyalkanoate and Recycling of Hydroxyalkonoate Monomer Obtained Thereby Via a Metabolic ProcessFebruary 2024January 2025Allow1110NoNo
18582510PRODUCTION METHOD OF ENZYMATIC REACTION USING ADENOSINE INSTEAD OF ATPFebruary 2024March 2025Allow1310YesNo
18441106Adherent Cell Culture Substrate Sampling DeviceFebruary 2024March 2025Allow1410YesNo
18436701LOW SHEAR MICROFLUIDIC DEVICES AND METHODS OF USE AND MANUFACTURING THEREOFFebruary 2024May 2025Abandon1510NoNo
18426195ESCHERICHIA COLI K-12 MG1655 BLBYZT6 AND APPLICATION THEREOFJanuary 2024March 2025Allow1440YesNo
18421205Orally Ingestible Delivery SystemJanuary 2024April 2025Allow1410NoNo
18419836ENZYME-ASSISTED ATRP PROCEDURESJanuary 2024April 2025Abandon1410NoNo
18409181METHODS TO IMPROVE ORGAN VIABILITYJanuary 2024December 2024Allow1210NoNo
18405102PREGABALIN ARTIFICIAL HAPTEN, ARTIFICIAL ANTIGEN AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOFJanuary 2024March 2025Allow1400YesNo
18402122BIOPLASTIC PRODUCTION METHODJanuary 2024April 2025Abandon1510NoNo
18399556RECOMBINANT ALGAE HAVING HIGH LIPID PRODUCTIVITYDecember 2023April 2025Allow1610YesNo
18535745TREATMENT OF PULMONARY ARTERIAL HYPERTENSION WITH PROSTACYCLIN-TREATED ENDOTHELIAL PROGENITOR CELLSDecember 2023January 2025Allow1410NoNo
18535865TREATMENT OF VASCULOPATHY WITH PROSTACYCLIN AND MESENCHYMAL STEM CELLSDecember 2023December 2024Allow1210NoNo
18532631METHOD FOR PREPARING ACTIVE PROTEIN PEPTIDE AND PREPARED ACTIVE PROTEIN PEPTIDE AND USE THEREOFDecember 2023September 2024Allow1010YesNo
18526264Novel Strain of Glutamicibacter, Originating from Insects, Capable of Efficiently Degrading BifenthrinDecember 2023June 2024Allow721NoNo
18524494BACTERIAL CULTURES AND METHODS FOR PRODUCTION OF ALGINATENovember 2023March 2025Allow1511YesNo
18523358METHODS OF PROCESSING LIGNOCELLULOSIC BIOMASS USING SINGLE-STAGE AUTOHYDROLYSIS AND ENZYMATIC HYDROLYSIS WITH C5 BYPASS AND POST-HYDROLYSISNovember 2023May 2025Allow1810NoNo
18520265TISSUE PRESERVATION SYSTEMNovember 2023December 2024Abandon1310NoNo
18516887GRANULE FOR DETECTING OCCULT BLOOD IN PET URINE AND METHOD FOR PREPARING THE SAMENovember 2023December 2024Abandon1320NoNo
18512646Bioerodible Matrix for Tissue InvolvementNovember 2023April 2025Abandon1710NoNo
18508109METHODS FOR VIRAL INACTIVATION AND OTHER ADVENTITIOUS AGENTSNovember 2023January 2025Abandon1401NoNo
18502098PROBIOTIC COMPOSITIONS AND USES THEREOFNovember 2023December 2024Allow1310YesNo
18559060EXIGUOBACTERIUM INDICUM AND APPLICATION THEREOF IN SYNTHESIS OF NANO-SELENIUMNovember 2023December 2024Allow1410NoNo
18387192METHOD OF ISOLATING MESENCHYMAL STEM CELLS FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORD, A MESENCHYMAL STEM CELL POPULATION ISOLATED FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORD AND A CELL CULTURE MEDIUM FOR ISOLATING MESENCHYMAL STEM CELLS FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORDNovember 2023February 2025Allow1610NoNo
18558863A Bioreactor and Process for Forming Polyhydroxybutyrate Directly from Depolymerized PolyhydroxybutyrateNovember 2023June 2025Allow1911YesNo
18499761SYSTEMS AND METHODS FOR PERFORMING ANTIMICROBIAL SUSCEPTIBILITY TESTINGNovember 2023January 2025Allow1410NoNo
18498807OIL OF MICROORGANISMS RICH IN DOCOSAHEXAENOIC ACIDOctober 2023March 2025Allow1610NoNo
18493878SENSORS FOR DETECTING AND IMAGING OF CANCER METASTASISOctober 2023June 2025Abandon2001NoNo
18493590ACONITIC ACID EXPORTER (AEXA) INCREASES ORGANIC ACID PRODUCTION IN ASPERGILLUSOctober 2023May 2025Allow1820YesNo
18382410SYSTEM FOR GROWING FUNGAL MATERIALSOctober 2023April 2025Abandon1811NoNo
18555515A composition comprising Pediococcus Pentosaceus for use in treatment and/or prevention of food and/or alcohol poisoningOctober 2023January 2025Allow1511YesNo
18286791PROCESS TO PRODUCE MONO-RHAMNOLIPIDSOctober 2023January 2025Allow1540NoNo
18485543Construction Method and Application of Microorganism Capable of Realizing High Production of Lacto-N-neotetraoseOctober 2023July 2024Allow911YesNo
18373435Caproate-producing bacterium with multiple substrate utilization capabilities and its applicationsSeptember 2023July 2024Allow1011YesNo
18472953Treatment of Anthrax with Pegylated Capsule-Degrading EnzymeSeptember 2023April 2024Allow710NoNo
18371651COMPOSITIONS AND METHOD OF USE FOR H5 COMPETENT BIFIDOBACTERIUM LONGUM SUBSP. INFANTISSeptember 2023June 2025Allow2111YesNo
18467280METHOD FOR PREPARING A TRANSFORMED, SALMO SALAR INTERFERON GAMMA (IFNG)-PRODUCING LACTOCOCCUS LACTIS BACTERIUMSeptember 2023January 2025Allow1610YesNo
18455533CELLULOSE NANOFIBRILLAR BIOINK FOR 3D BIOPRINTING FOR CELL CULTURING, TISSUE ENGINEERING AND REGENERATIVE MEDICINE APPLICATIONSAugust 2023February 2025Abandon1801NoNo
18237027FERROUS PEBBLES AS A CATALYST FOR ENHANCED METHANE GENERATION FROM RICE HUSKAugust 2023November 2023Allow200YesNo
18453712METHODS OF PRODUCING RPE CELLSAugust 2023October 2024Allow1420NoNo
18451977BONE GRAFTS INCLUDING OSTEOGENIC STEM CELLS, AND METHODS RELATING TO THE SAMEAugust 2023July 2024Allow1110NoNo
18450812Anti-Fatigue Lactobacillus Composition and Use ThereofAugust 2023September 2024Abandon1311NoNo
18447649O-METHYLTRANSFERASE PROTEIN WITH HIGHLY SPECIFIC CATALYTIC FUNCTION FOR MULTIPLE BIAS PARENT NUCLEI AND ENCODING GENE AND USE THEREOFAugust 2023June 2024Allow1011YesNo
18364151BACTERIAAugust 2023May 2025Allow2211NoNo
18358682METHODS AND COMPOSITIONS FOR TREATING SOIL AND PLANTSJuly 2023September 2024Allow1411YesNo
18358046METHOD FOR IMPROVING GUT MICROBIOTA WITH LACTIPLANTIBACILLUS PLANTARUM TCI837July 2023October 2024Allow1520NoNo
18225360MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITROJuly 2023November 2024Abandon1610NoNo
18351696ENGINEERED MIGRASOME, METHOD FOR PREPARING SAME, AND USES THEREOFJuly 2023September 2024Allow1521YesNo
18220535METHODS TO GENERATE POLYMER SCAFFOLDS HAVING A GRADIENT OF CROSSLINKING DENSITYJuly 2023May 2025Abandon2221NoNo
18345619STABLE BACTERIAL EXTRACTS AS PHARMACEUTICALSJune 2023March 2025Abandon2020NoNo
18341692METHODS OF PREPARING T CELLS FOR T CELL THERAPYJune 2023February 2025Abandon2020YesNo
18339218CUTINASE HAVING IMPROVED ENZYMATIC ACTIVITYJune 2023December 2023Allow600NoNo
18338189PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOFJune 2023January 2024Allow610NoNo
18208713APPARATUS AND METHOD FOR PRETREATMENT OF MICROBIAL SAMPLESJune 2023September 2024Abandon1520NoNo
18324954METHOD FOR ASSESSING MICROBIAL DRUG RESISTANCE MULTI-LEVEL RISKS OF ANTIBIOTIC RESIDUES IN WATER ENVIRONMENTMay 2023January 2024Allow810NoNo
18324416CELLULOSE SACCHARIFICATION METHODMay 2023October 2024Abandon1620NoNo
18253861METHOD FOR PREPARING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF BY ENZYMATIC-CHEMICAL CASCADE METHODMay 2023May 2024Allow1210YesNo
18319085METHOD OF PRODUCING THIN ENZYME-BASED SENSING LAYERS ON PLANAR SENSORSMay 2023December 2023Allow700YesNo
18196574METHOD FOR TREATING PARKINSON�S DISEASE BY USING PARABACTEROIDES GOLDSTEINIIMay 2023October 2024Abandon1810NoNo
18035938METHOD FOR DETECTING ORGANOPHOSPHORUS PESTICIDE BY MICROFLUIDIC CHIP BASED ON FLUORESCENT SENSING FILMMay 2023February 2025Allow2210NoNo
18137254SYSTEMS AND METHODS FOR STAINING OF BIOLOGICAL SAMPLESApril 2023June 2025Allow2621NoNo
18135116METHOD OF PREPARING PROCOLLAGEN FROM FRESHWATER FISHApril 2023June 2025Abandon2630NoNo
18031556ENGINEERED MICROORGANISMS EXPRESSING ACETOACETYL- COA REDUCTASE VARIANTS AND METHODS FOR INCREASING PROPORTION OF 3-HYDROXYHEXANOIC ACID IN PHAApril 2023December 2024Allow2011YesNo
18295384DEVICE AND METHOD FOR CONTROLLING A BIOREACTORApril 2023November 2024Allow1910NoNo
18191201METHOD FOR PREPARING FIBER MATERIAL FROM BANANA PSEUDOSTEMMarch 2023April 2025Abandon2530NoNo
18186488LAMBDA-CARRAGEENASE MUTANT OUC-CGLA-DPQQ AND APPLICATION THEREOFMarch 2023January 2025Abandon2221NoNo
18026593METHOD FOR PRODUCING BIOGAS FROM WASTE LIQUID/RESIDUE AFTER DIOSGENIN EXTRACTION FROM DIOSCOREA COMPOSITA BY ALUMINUM CHLORIDEMarch 2023January 2024Allow1011NoNo
18183262METHOD FOR TREATMENT AND CONTROL OF PLANT DISEASEMarch 2023February 2024Allow1110NoNo
18119339SYSTEM AND METHODS FOR MULTIPLEXED ANALYSIS OF CELLULAR AND OTHER IMMUNOTHERAPEUTICSMarch 2023November 2024Allow2001NoNo
18024502STABILIZER FOR COLOR DEVELOPING AGENT AND APPLICATION THEREOF, APPLICATION OF COMPOSITION IN PREPARATION OF STABILIZER, AND KITMarch 2023August 2024Allow1730YesNo
18177070SIALYLTRANSFERASES FOR IN VIVO SYNTHESIS OF 3'SLMarch 2023August 2024Allow1811NoNo
18114861METHODS AND COMPOSITIONS TO MAINTAIN STEM CELL QUIESCENCEFebruary 2023November 2024Allow2010NoNo
18174165TCRa HOMING ENDONUCLEASE VARIANTSFebruary 2023November 2024Allow2120NoYes
18170669ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATIONFebruary 2023February 2025Allow2420NoNo
17909760BACILLUS VELEZENSIS STRAIN BRED THROUGH ULTRASOUND-ASSISTED ADAPTIVE EVOLUTION, AND USE THEREOFFebruary 2023January 2025Abandon2801NoNo
18110427Method for Tissue Sample FixationFebruary 2023July 2024Allow1710YesNo
18170196SCREENING METHODFebruary 2023May 2024Allow1510NoNo
18110861APPARATUS AND METHOD OF USING A SIMULATED SKIN SUBSTRATE FOR TESTING INSECT REPELLANTSFebruary 2023December 2024Allow2221YesNo
18169487MICROORGANISM PRODUCING EICOSAPENTAENOIC ACID AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACIDFebruary 2023March 2024Allow1330YesNo
18108849METHOD FOR ASSESSING VALIDITY OF CELL THERAPY PRODUCTFebruary 2023January 2025Abandon2330NoNo
18107951PROCESSING SYSTEM FOR PROCESSING SPECIMENS USING ACOUSTIC ENERGYFebruary 2023September 2024Allow2011NoNo
18166412METHOD FOR STABILIZATION AND DELIVERY OF THERAPEUTIC MOLECULESFebruary 2023September 2024Allow1930YesNo
18105758SIMPLE FIXATION AND STABILISATIONFebruary 2023October 2024Abandon2111NoNo
18040418Method To Sense the Presence and Activity of Microbes Through the Use of Transient Sensing MaterialsFebruary 2023December 2024Allow2221NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1657.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
125
Examiner Affirmed
92
(73.6%)
Examiner Reversed
33
(26.4%)
Reversal Percentile
19.7%
Lower than average

What This Means

With a 26.4% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
785
Allowed After Appeal Filing
213
(27.1%)
Not Allowed After Appeal Filing
572
(72.9%)
Filing Benefit Percentile
21.0%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 27.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

⚠ Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

⚠ Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Art Unit 1657 - Prosecution Statistics Summary

Executive Summary

Art Unit 1657 is part of Group 1650 in Technology Center 1600. This art unit has examined 9,583 patent applications in our dataset, with an overall allowance rate of 58.4%. Applications typically reach final disposition in approximately 35 months.

Comparative Analysis

Art Unit 1657's allowance rate of 58.4% places it in the 12% percentile among all USPTO art units. This art unit has a significantly lower allowance rate than most art units at the USPTO.

Prosecution Patterns

Applications in Art Unit 1657 receive an average of 1.88 office actions before reaching final disposition (in the 56% percentile). The median prosecution time is 35 months (in the 19% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more challenging examination environment compared to the USPTO average.
  • With more office actions than average, plan for relatively streamlined prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.