USPTO Examiner LANKFORD JR LEON B - Art Unit 1657

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19205490TREATMENT OF FISTULA WITH BONE MARROW MESENCHYMAL STEM CELL DERIVED EXTRACELLULAR VESICLESMay 2025November 2025Allow610YesNo
19055164Treatment for Chronic Kidney DiseaseFebruary 2025October 2025Abandon810NoNo
18933318COLLAGEN AND USE THEREOFOctober 2024August 2025Allow1011YesNo
18787118COMPOSITIONS AND METHODS OF PREPARING AIRWAY CELLSJuly 2024January 2026Allow1810NoNo
18786855ENGINEERING MECHANICALLY FUNCTIONAL HUMAN CARTILAGE AND METHOD OF MAKING SAMEJuly 2024March 2026Allow1910NoNo
18679906COMPOSITIONS AND METHODS FOR OBTAINING ORGANOIDSMay 2024March 2025Allow1010YesNo
18656253Perfusion Culturing Methods and Uses ThereofMay 2024April 2025Allow1110NoNo
18622012ORGANOTYPIC DRG-PERIPHERAL NERVE CULTURE SYSTEMMarch 2024March 2025Allow1110YesNo
18606318METHOD OF FORMING A MYCOLOGICAL PRODUCTMarch 2024April 2025Allow1310NoNo
18603954SYSTEMS AND METHODS FOR MONITORING TISSUE SAMPLE PROCESSINGMarch 2024September 2025Allow1811NoNo
18686912Depolymerization of a Polyhydroxyalkanoate and Recycling of Hydroxyalkonoate Monomer Obtained Thereby Via a Metabolic ProcessFebruary 2024January 2025Allow1110NoNo
18441106Adherent Cell Culture Substrate Sampling DeviceFebruary 2024March 2025Allow1410YesNo
18436701LOW SHEAR MICROFLUIDIC DEVICES AND METHODS OF USE AND MANUFACTURING THEREOFFebruary 2024May 2025Abandon1510NoNo
18409181METHODS TO IMPROVE ORGAN VIABILITYJanuary 2024December 2024Allow1210NoNo
18406886CYTOPHERESIS CARTRIDGES AND USE THEREOFJanuary 2024July 2025Allow1810NoNo
18541238MULTISTRAIN POPULATION CONTROL SYSTEMS AND METHODSDecember 2023January 2026Allow2511YesNo
18535865TREATMENT OF VASCULOPATHY WITH PROSTACYCLIN AND MESENCHYMAL STEM CELLSDecember 2023December 2024Allow1210NoNo
18535745TREATMENT OF PULMONARY ARTERIAL HYPERTENSION WITH PROSTACYCLIN-TREATED ENDOTHELIAL PROGENITOR CELLSDecember 2023January 2025Allow1410NoNo
18512646Bioerodible Matrix for Tissue InvolvementNovember 2023April 2025Abandon1710NoNo
18389470ENGINEERED MATERIALS AND METHODS OF FORMINGNovember 2023July 2025Allow2010YesNo
18387192METHOD OF ISOLATING MESENCHYMAL STEM CELLS FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORD, A MESENCHYMAL STEM CELL POPULATION ISOLATED FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORD AND A CELL CULTURE MEDIUM FOR ISOLATING MESENCHYMAL STEM CELLS FROM THE AMNIOTIC MEMBRANE OF THE UMBILICAL CORDNovember 2023February 2025Allow1610NoNo
18499761SYSTEMS AND METHODS FOR PERFORMING ANTIMICROBIAL SUSCEPTIBILITY TESTINGNovember 2023January 2025Allow1410NoNo
18498807OIL OF MICROORGANISMS RICH IN DOCOSAHEXAENOIC ACIDOctober 2023March 2025Allow1610NoNo
18553977PROCESS FOR THE PREPARATION OF A SUGAR PRODUCT AND A FERMENTATION PRODUCTOctober 2023March 2026Allow2910NoNo
18553487HYALURONIC ACID-PRODUCING RECOMBINANT CELLSSeptember 2023March 2026Allow2910NoNo
18453712METHODS OF PRODUCING RPE CELLSAugust 2023October 2024Allow1420NoNo
18364151BACTERIAAugust 2023May 2025Allow2211NoNo
18275125CULTURE MEDIUM AND CULTURE METHOD FOR PRIMARY CELLS OF INTESTINAL CANCERJuly 2023January 2026Allow2910YesNo
18225360MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITROJuly 2023November 2024Abandon1610NoNo
18215601ANTIBIOTIC SUSCEPTIBILITY EVALUATION APPARATUSJune 2023December 2025Allow2910NoNo
18027203CELLULAR MICROCOMPARTMENTS COMPRISING HUMAN CELLS UNDERGOING CARDIAC DIFFERENTIATION, TISSUES OBTAINED FROM SAID MICROCOMPARTMENTS AND USES THEREOFJune 2023January 2026Allow3410NoNo
18214190BIOGAS COLLECTION APPARATUS AND METHOD OF USEJune 2023March 2026Allow3310NoNo
18269001NEURAL STEM CELL-INDUCED DIFFERENTIAL MEDIUM AND INDUCTION DIFFERENTIATION METHODJune 2023January 2026Allow3110YesNo
18268639CELL CULTURE METHODJune 2023August 2025Allow2600YesNo
18137254SYSTEMS AND METHODS FOR STAINING OF BIOLOGICAL SAMPLESApril 2023June 2025Allow2621NoNo
18303247METHODS, DEVICES, AND COMPUTER PROGRAM PRODUCTS FOR STANDARDIZING A FERMENTATION PROCESSApril 2023September 2025Allow2811NoNo
18132087BONE DERIVED FIBERS AND OXYGENATED WOUND TREATMENTSApril 2023July 2025Allow2731YesNo
18114861METHODS AND COMPOSITIONS TO MAINTAIN STEM CELL QUIESCENCEFebruary 2023November 2024Allow2010NoNo
18113281ULTRA-HIGH DENSITY CELL BANKING METHODSFebruary 2023March 2026Allow3730NoNo
18170669ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATIONFebruary 2023February 2025Allow2420NoNo
18110427Method for Tissue Sample FixationFebruary 2023July 2024Allow1710YesNo
18107951PROCESSING SYSTEM FOR PROCESSING SPECIMENS USING ACOUSTIC ENERGYFebruary 2023September 2024Allow2011NoNo
18154461AMNION TISSUE GRAFTS AND METHODS OF PREPARING AND USING SAMEJanuary 2023November 2024Allow2220YesNo
18094770Compositions and Methods for Stabilizing Circulating Tumor CellsJanuary 2023June 2024Allow1710NoNo
18014224Extracellular Vesicles (EVs) Derived from Mesenchymal Stromal Cells and Method for Obtaining Said EVsJanuary 2023January 2026Allow3610NoNo
18068137Engineered Three-Dimensional Skin Tissues, Arrays Thereof, and Methods of Making the SameDecember 2022November 2025Allow3510YesNo
18010906TRANSPARENTIZING PRETREATMENT METHOD OF BIOLOGICAL SAMPLE HAVING SIZE OF AT MOST 1 MM, AND TRANSPARENTIZING METHOD OF BIOLOGICAL SAMPLE INCLUDING SAMEDecember 2022May 2025Allow2911NoNo
18002101COMPOSITION FOR BONE REGENERATION COMPRISING METTL7A OVEREXPRESSING STEM CELLS, METHOD FOR PREPARING SAME, AND CELL THERAPY PRODUCT COMPRISING SAMEDecember 2022December 2025Allow3610NoNo
18063600SYSTEMS AND METHODS FOR OPTIMIZED PATIENT SPECIFIC TISSUE ENGINEERING VASCULAR GRAFTSDecember 2022June 2024Allow1810NoNo
18075919METHODS AND MATERIALS FOR REDUCING VENOUS NEOINTIMAL HYPERPLASIA OF AN ARTERIOVENOUS FISTULA OR GRAFTDecember 2022June 2024Allow1810NoNo
17993343COMPOSITION AND METHOD FOR TREATING CANCERNovember 2022May 2024Allow2821YesNo
17973220SUSPENSION COMPOSITION FOR HEMATOLOGY ANALYSIS CONTROLOctober 2022May 2025Allow3020NoNo
17919453REGENERATIVE NONSTEROIDAL ANTI-INFLAMMATORY COMPOSITIONS, METHODS OF PRODUCTION, AND METHODS OF USE THEREOFOctober 2022March 2026Abandon4110NoNo
17961478TOPICAL COMPOSITION FOR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASEOctober 2022August 2024Abandon2210NoNo
17937155METHODS OF INCREASING PROGENITOR CELL PRODUCTIONSeptember 2022December 2025Abandon3801NoNo
17929052FIBROBLAST HAVING ENHANCED ERYTHROPOIETIN PRODUCTION ABILITYSeptember 2022November 2025Abandon3910NoNo
17822663CONTROLLED GROWTH OF MICROORGANISMSAugust 2022January 2025Allow2820NoNo
17881453METHODS AND COMPOSITIONS FOR CRYOPRESERVATION OF CELL THERAPIESAugust 2022October 2025Allow3821YesNo
17866804METHOD OF IN SITU REMEDIATION OF SOILS USING A BIOREMEDIATION COMPOSITION INCLUDING A TIME RELEASE MATERIALJuly 2022December 2024Allow2911NoNo
17813192MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES AND USES THEREOF FOR TREATING AND DIAGNOSING FIBROTIC DISEASESJuly 2022August 2025Allow3710YesNo
17865875ANTI-FIBROSIS AGENT AND METHOD OF PRODUCING EXTRACELLULAR VESICLE HAVING ANTI-FIBROSIS ACTIONJuly 2022September 2025Allow3830YesNo
17864633ANGIOGENESIS AGENT AND METHOD OF PRODUCING EXTRACELLULAR VESICLE HAVING ANGIOGENESIS ACTIONJuly 2022September 2025Allow3820YesNo
17792771PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALZHEIMER'S AND USE THEREOFJuly 2022March 2026Abandon4401NoNo
17792397USE OF NOCARDIA RUBRA CELL WALL SKELETON IN REGENERATIVE MEDICINEJuly 2022November 2025Allow4110YesNo
17856085COMPOSITIONS AND METHODS OF PREPARING AIRWAY CELLSJuly 2022April 2024Allow2210NoNo
17844829System and Process for Increasing Protein Product Yield from Bacterial CellsJune 2022April 2024Allow2210YesNo
17844198BUSINESS METHODS, PROCESSES AND SYSTEMS FOR COLLECTION, CRYOGENIC STORAGE AND DISTRIBUTION OF COSMETIC FORMULATIONS FROM AN OBTAINED STEM CELL BASED BIOLOGICAL MATERIALJune 2022September 2024Abandon2701NoNo
17826637METHODS AND SYSTEMS FOR RAPID CONTINUOUS FLOW PATHOGEN CELL LYSIS IN A MICROFLUIDIC CHANNELMay 2022June 2024Allow2510NoNo
17664856CELL THERAPIES AND METHODS OF TREATMENT FOR SMALL-VOLUME STROKEMay 2022July 2024Allow2621NoNo
17748189COMPOSITIONS CAPABLE OF STIMULATING IMMUNITY TOWARDS TUMOR BLOOD VESSELSMay 2022April 2025Abandon3501NoNo
17777856GENERATION OF KIDNEY GLOMERULAR SPECIFIC ENDOTHELIAL CELLS AND METHODS OF USEMay 2022September 2025Allow4010YesNo
17774562COMPOSITION FOR PREVENTING OR TREATING RENAL DISEASES, COMPRISING EXOSOMES DERIVED FROM PRECURSOR CELLS OF INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLSMay 2022October 2025Allow4210NoNo
17773556THERAPY FOR INTERSTITIAL CYSTITIS BY PLURIPOTENT STEM CELLSApril 2022August 2025Allow3910NoNo
17658439ASEPTIC CELL PROCESSING AND PRODUCTION WITH NO CHEMICAL BIOCIDESApril 2022October 2024Allow3020NoNo
17765881CHIMERIC ANTIGEN RECEPTOR SPECIFICALLY BINDING TO CD138, IMMUNE CELL EXPRESSING SAME, AND ANTICANCER USE THEREOFApril 2022December 2025Abandon4401NoNo
17710418COMPOSITIONS AND METHODS FOR TREATING AMYOTROPHIC LATERAL SCLEROSISMarch 2022November 2025Allow4411YesNo
17632752METHODS AND COMPOSITIONS FOR RECONSTITUTING MICROGLIAFebruary 2022November 2025Allow4510YesNo
17587528METHODS AND COMPOSITIONS FOR MODULATING PD1January 2022February 2026Abandon4911NoNo
17587685METHODS FOR ENHANCING LIFESPAN AND/OR TREATING CELLULAR PROLIFERATIVE DISORDERS BY TRANSPLANTATIONJanuary 2022February 2026Allow4811YesNo
17628011PREPARATIONS COMPRISING MESENCHYMAL STEM CELLS AND CANNABINOIDS AND METHODS OF THEIR USEJanuary 2022October 2024Allow3310NoNo
17572227TRANSPARENT SKIN SAMPLEJanuary 2022May 2025Abandon4130NoNo
17572330SLOW INTRAVENTRICULAR DELIVERYJanuary 2022May 2025Abandon4020NoYes
17569634PLURIPOTENT STEM CELL MANUFACTURING SYSTEM AND METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLSJanuary 2022March 2025Abandon3820NoNo
17623735IMMUNOTHERAPY TARGETING CELL SURFACE MARKER CD72 FOR THE TREATMENT OF B-CELL MALIGNANCIESDecember 2021October 2025Abandon4501NoNo
17622288Production Method of (R)-ReticulineDecember 2021March 2025Allow3921YesNo
17419420CD7 CHIMERIC ANTIGEN RECEPTOR-MODIFIED NK-92MI CELL AND USE THEREOFDecember 2021September 2025Abandon5001NoNo
17550949METHODS FOR HARVESTING MICROALGAEDecember 2021February 2024Abandon2610YesNo
17542051INDOOR FOOD WASTE FERMENTATION AND RECYCLING PROCESSDecember 2021February 2024Abandon2610NoNo
17616489UNSPECIFIC PEROXYGENASE ENZYME VARIANTS FOR SELECTIVE FATTY ACID EPOXIDATION OR HYDROXYLATIONDecember 2021March 2025Allow3911YesNo
17615540METHODS FOR TREATING METABOLIC DISORDERS BY TARGETING ADCY5November 2021January 2026Allow4911NoNo
17456136CONTROLLED PRINTING OF A CELL SAMPLE FOR KARYOTYPINGNovember 2021November 2024Allow3630NoNo
17612934NR4A SUPER-REPRESSORS AND METHODS OF USE THEREOFNovember 2021December 2025Allow4811YesNo
17527422IN VITRO GASTROINTESTINAL MODEL COMPRISING LAMINA PROPRIA-DERIVED CELLSNovember 2021June 2025Abandon4311NoNo
17610181METHODS AND MATERIALS FOR TREATING CARDIOVASCULAR DISEASESNovember 2021October 2025Abandon4730NoNo
17519655ENRICHMENT OF SURGICAL SPECIMENS FOR TUMOR TISSUENovember 2021March 2025Allow4010NoNo
17608252ALKALINE PHOSPHATE-BASED ONCOLOGY TREATMENTSNovember 2021January 2025Allow3911NoNo
17608359DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSIONNovember 2021July 2025Abandon4401NoNo
17607592ANTIGEN SPECIFIC CD19-TARGETED CAR-T CELLSOctober 2021November 2025Allow4911YesNo
17606167MEMBRANE PROTEASE-BASED METHODS FOR DETECTION OF BACTERIAOctober 2021March 2025Allow4111YesNo
17506831ENGINEERING MECHANICALLY FUNCTIONAL HUMAN CARTILAGE AND METHOD OF MAKING SAMEOctober 2021March 2024Allow2910NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner LANKFORD JR, LEON B.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
2
Examiner Affirmed
1
(50.0%)
Examiner Reversed
1
(50.0%)
Reversal Percentile
70.1%
Higher than average

What This Means

With a 50.0% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
29
Allowed After Appeal Filing
10
(34.5%)
Not Allowed After Appeal Filing
19
(65.5%)
Filing Benefit Percentile
56.7%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 34.5% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner LANKFORD JR, LEON B - Prosecution Strategy Guide

Executive Summary

Examiner LANKFORD JR, LEON B works in Art Unit 1657 and has examined 464 patent applications in our dataset. With an allowance rate of 82.1%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 36 months.

Allowance Patterns

Examiner LANKFORD JR, LEON B's allowance rate of 82.1% places them in the 54% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by LANKFORD JR, LEON B receive 1.96 office actions before reaching final disposition. This places the examiner in the 49% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by LANKFORD JR, LEON B is 36 months. This places the examiner in the 35% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +13.9% benefit to allowance rate for applications examined by LANKFORD JR, LEON B. This interview benefit is in the 52% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 29.8% of applications are subsequently allowed. This success rate is in the 57% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 52.7% of cases where such amendments are filed. This entry rate is in the 79% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 125.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 83% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences are highly effective with this examiner compared to others. Before filing a full appeal brief, strongly consider requesting a PAC. The PAC provides an opportunity for the examiner and supervisory personnel to reconsider the rejection before the case proceeds to the PTAB.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 90.5% of appeals filed. This is in the 83% percentile among all examiners. Of these withdrawals, 68.4% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 65.6% are granted (fully or in part). This grant rate is in the 71% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 1.9% of allowed cases (in the 74% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Request pre-appeal conferences: PACs are highly effective with this examiner. Before filing a full appeal brief, request a PAC to potentially resolve issues without full PTAB review.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.