USPTO Technology Center 1600 Prosecution Statistics

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19417541ACACIA NILOTICA BASED HYDROGEL AND METHOD OF MAKING THE SAMEDecember 2025February 2026Allow200NoNo
19382964METHOD FOR MAKING METHANE FROM CARBON DIOXIDENovember 2025March 2026Allow400NoNo
19383003METHOD FOR MAKING A BENZIMIDAZOLENovember 2025March 2026Allow400NoNo
19376432ALBUMIN BINDING PROTEINS AND METHODS OF USEOctober 2025February 2026Allow400YesNo
19375973FRAGMENTING RNA:DNA HYBRIDSOctober 2025January 2026Allow300YesNo
19371517HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSOctober 2025March 2026Allow400YesNo
19371529HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSOctober 2025March 2026Allow500YesNo
19364654METHODS OF TREATING DISORDERS USING CSF1R INHIBITORSOctober 2025February 2026Allow410NoNo
19364297FORMULATIONS OF ANTI-CD38 ANTIBODIES FOR SUBCUTANEOUS ADMINISTRATIONOctober 2025March 2026Allow400YesNo
19361770COMPOSITIONS AND METHODS FOR MOLECULAR LABELINGOctober 2025March 2026Allow510NoNo
19357447ANAPLASTIC LYMPHOMA KINASE (ALK) DEGRADERS AND USES THEREOFOctober 2025January 2026Allow300NoNo
18831858Delosperma plant named 'Electric Slide'October 2025January 2026Allow300NoNo
19355669MUSCLE-SPECIFIC EXPRESSION CASSETTESOctober 2025March 2026Allow500NoNo
19352234SUBSTITUTED HETEROCYCLES AND USES THEREOFOctober 2025December 2025Allow200NoNo
19352045BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINEOctober 2025December 2025Allow200NoNo
19352098PD-L1 ANALOG FUSION PROTEINS FOR ANTIGEN SPECIFIC IMMUNOTHERAPY AND METHODS OF USEOctober 2025February 2026Allow510NoNo
19350804LIGAND DISCOVERY AND GENE DELIVERY VIA RETROVIRAL SURFACE DISPLAYOctober 2025January 2026Allow310NoNo
19350928LIGAND DISCOVERY AND GENE DELIVERY VIA RETROVIRAL SURFACE DISPLAYOctober 2025January 2026Allow310NoNo
19350944HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSOctober 2025December 2025Allow300YesNo
19350939HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSOctober 2025February 2026Allow500YesNo
19350933HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSOctober 2025February 2026Allow500YesNo
19350713ADVANTAGEOUS MORPHIC FORM OF AT-527 HEMI-SULFATE SALTOctober 2025March 2026Abandon510NoNo
19347136ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOMEOctober 2025March 2026Allow511YesNo
19344588BRAND-NEW SKELETON 99MTC-FAPI DIAGNOSTIC PROBE AND USE THEREOF IN PREPARATION OF DRUG OR REAGENT FOR DIAGNOSING TUMORSSeptember 2025February 2026Allow510NoNo
19345445METHODS AND KITS FOR PREDICTING INFUSION REACTION RISK AND ANTIBODY-MEDIATED LOSS OF RESPONSE BY MONITORING SERUM URIC ACID DURING PEGYLATED URICASE THERAPYSeptember 2025January 2026Allow310YesNo
19343371THERAPEUTIC COMPOSITIONS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUSSeptember 2025February 2026Allow510NoNo
19340137SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORSSeptember 2025January 2026Allow410NoNo
19339250Intraoral Cleaning TabletSeptember 2025December 2025Allow300NoNo
19333265Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) AntibodiesSeptember 2025March 2026Allow610NoNo
18831815INTERSPECIFIC TREE Named 'Flavor Chief'September 2025November 2025Allow200YesNo
19329790PETUNIA PLANT NAMED 'WNPETSVBG27'September 2025December 2025Allow300NoNo
18831801Miniature Rose Plant Named 'Poulpal097'September 2025March 2026Allow610YesNo
18831797Hybrid Tea Rose Plant Named 'Poulpmt010'September 2025December 2025Allow300NoNo
18831799Miniature Rose Plant Named 'Poulpah 125'September 2025December 2025Allow300NoNo
19329242PHALAENOPSIS PLANT NAMED 'PHA329495'September 2025December 2025Allow300NoNo
18831805Miniature rose plant named 'Poulpar137'September 2025February 2026Allow500NoNo
18831806Miniature Rose Plant Named 'Poulty038'September 2025February 2026Allow500NoNo
18831808Miniature Rose Plant Named 'Poulty046'September 2025January 2026Allow410NoNo
19327881MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOFSeptember 2025January 2026Allow410YesNo
19327867MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOFSeptember 2025March 2026Allow611YesNo
19328055PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDESSeptember 2025December 2025Allow300YesNo
19327711METHODS OF IMPROVING LUNG FUNCTIONSeptember 2025March 2026Allow610NoNo
19327682METHODS OF IMPROVING LUNG FUNCTIONSeptember 2025March 2026Allow610NoNo
19326225DRY POWDER FORMULATIONS OF EPINEPHRINE AND ASSOCIATED METHODSSeptember 2025February 2026Allow610NoNo
19324663MARINE ORGANISM INFUSED EFFERVESCENT TABLET FOR PRODUCING ENHANCED SUSPENSIONSSeptember 2025January 2026Allow401YesNo
19324396MARINE ORGANISM DERIVED SURFACTANTSeptember 2025February 2026Allow501NoNo
19323422PHARMACEUTICAL COMPOSITION FOR KERATOSIS AND USE THEREOFSeptember 2025March 2026Allow601YesNo
19323694STIMULANT COMPOSITION AND PROCESS FOR MAKING SAMESeptember 2025December 2025Allow400YesNo
19323583COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACIDSeptember 2025October 2025Allow200NoNo
18831789Allium Plant Named 'All The Buzz'September 2025October 2025Allow100NoNo
18831788Epimedium plant named 'Jester's Hat'September 2025November 2025Allow200NoNo
19322628CAPSID VARIANTS AND METHODS OF USING THE SAMESeptember 2025February 2026Allow510NoNo
19320604COMPOUNDS FOR TARGETED PROTEIN DEGRADATIONSeptember 2025February 2026Allow511NoNo
19320567SHEPHERDIA PLANT NAMED 'TORREY'September 2025March 2026Allow610NoNo
19320020CHEMICAL COMPOUNDS AND USES THEREOFSeptember 2025February 2026Allow510NoNo
19319209AQUEOUS COMPOSITIONSeptember 2025February 2026Allow510YesNo
19319360CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USESeptember 2025January 2026Allow501YesNo
19318311METHODS FOR DETECTING INTERCELLULAR INTERACTIONS OF CELLS IN A COMPARTMENT OF A FLUIDIC DEVICESeptember 2025January 2026Allow510YesNo
19318315METHODS FOR INCUBATING AND ANALYZING A CELL IN A COMPARTMENT OF A FLUIDIC DEVICESeptember 2025January 2026Allow510YesNo
19317897METHOD FOR EXTRACTING UNFRACTIONATED HEPARIN FROM CAMEL INTESTINAL MUCOSASeptember 2025January 2026Allow510NoNo
19316708SELF-REGULATING PHOTO-CURABLE COOLING HYDROGEL AND PREPARATION METHOD AND APPLICATION THEREOFSeptember 2025January 2026Allow401YesNo
19316633IL13 AND IL31 BISPECIFIC POLYPEPTIDES AND USES THEREOFSeptember 2025December 2025Allow300NoNo
19316641EPIPREMNUM PLANT NAMED 'ETH'September 2025November 2025Allow300NoNo
19317124Kalanchoe Plant Named 'KLEKB24054'September 2025November 2025Allow200NoNo
19316629PHALAENOPSIS PLANT NAMED 'PHA569755'September 2025November 2025Allow200NoNo
19315655Chamaecyparis Plant Named 'Edengra 23'September 2025November 2025Allow200NoNo
19315583ANTHURIUM PLANT NAMED 'AN2244532'August 2025October 2025Allow200YesNo
19315581ANTHURIUM PLANT NAMED 'AN2181990'August 2025November 2025Allow300NoNo
19315587ANTHURIUM PLANT NAMED 'AN2541672'August 2025November 2025Allow300NoNo
19315584ANTHURIUM PLANT NAMED 'AN2297549'August 2025November 2025Allow200NoNo
19314145Euphorbia Plant Named 'Miner's Berry Bordeaux'August 2025October 2025Allow200YesNo
19315079S-BETA-HYDROXYBUTYRATE ESTERS FOR IMPROVING METABOLIC FUNCTIONAugust 2025January 2026Allow510NoNo
19312645CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025January 2026Allow410NoNo
19312755CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025January 2026Allow410NoNo
19312786CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025January 2026Allow410NoNo
19313046CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025February 2026Allow610NoNo
19313010CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025February 2026Allow610NoNo
19312656CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITORAugust 2025December 2025Allow300NoNo
19313576MANDEVILLA PLANT NAMED 'TVMD944'August 2025October 2025Allow200NoNo
19313647MANDEVILLA PLANT NAMED 'TVMD1232'August 2025October 2025Allow200NoNo
19313635MANDEVILLA PLANT NAMED 'TVMD1143'August 2025October 2025Allow200NoNo
19313539MANDEVILLA PLANT NAMED 'TVMD714'August 2025October 2025Allow200NoNo
19313675MANDEVILLA PLANT NAMED 'TVMD1626'August 2025December 2025Allow400NoNo
19313668MANDEVILLA PLANT NAMED 'TVMD1573'August 2025November 2025Allow200NoNo
19313653MANDEVILLA PLANT NAMED 'TVMD1330'August 2025November 2025Allow200NoNo
19313602MANDEVILLA PLANT NAMED 'TVMD982'August 2025October 2025Allow200NoNo
19313620MANDEVILLA PLANT NAMED 'TVMD1037'August 2025November 2025Allow300NoNo
19313568MANDEVILLA PLANT NAMED 'TVMD932'August 2025November 2025Allow200YesNo
19312906HYDROXYPROPYL BETA-CYCLODEXTRIN COMPOSITIONS AND METHODSAugust 2025February 2026Allow600YesNo
19311629UROLITHIN GUMMY (PECTIN) FORMULATIONSAugust 2025February 2026Allow510NoNo
19311344Selective Serotonin Receptor Modulators and Methods of Making and Using the SameAugust 2025January 2026Allow511YesNo
19311988SYSTEMS AND METHODS TO DETECT RARE MUTATIONS AND COPY NUMBER VARIATIONAugust 2025March 2026Allow610NoNo
19309669NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOFAugust 2025December 2025Allow400YesNo
19310812REVERSE TRANSCRIPTASE VARIANTSAugust 2025November 2025Allow300YesNo
19310785ROSA PLANT NAMED 'GEN R273'August 2025October 2025Allow200NoNo
19310827PHALAENOPSIS PLANT NAMED 'FLORICHROME'August 2025October 2025Allow200NoNo
19310781HYBRID TEA ROSE PLANT NAMED 'ESM R895'August 2025October 2025Allow200NoNo
193094482-DIARYLMETHYL-4-AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTSAugust 2025November 2025Allow200YesNo
19308863RAS INHIBITORSAugust 2025December 2025Allow410NoNo
19309246BACTERIOPHAGE COMPOSITIONS FOR TREATING STAPHYLOCOCCUS INFECTIONAugust 2025March 2026Allow701YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for tech-center 1600.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
10812
Examiner Affirmed
7592
(70.2%)
Examiner Reversed
3220
(29.8%)
Reversal Percentile
20.0%
Lower than average

What This Means

With a 29.8% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
62896
Allowed After Appeal Filing
13715
(21.8%)
Not Allowed After Appeal Filing
49181
(78.2%)
Filing Benefit Percentile
9.1%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 21.8% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Technology Center 1600 - Biotechnology and Organic Chemistry

Executive Summary

Technology Center 1600 covers Biotechnology and Organic Chemistry. This technology center has examined 687,967 patent applications in our dataset, with an overall allowance rate of 60.0%. Applications typically reach final disposition in approximately 31 months.

Prosecution Patterns

Applications in Technology Center 1600 receive an average of 1.86 office actions before reaching final disposition. The median prosecution time is 31 months.

Technology-Specific Considerations

This technology center encompasses a broad range of technical subject matter. Prosecution strategies should be tailored based on the specific art unit and examiner assigned to your application. Review the group, art unit, and examiner-level statistics for more targeted strategic insights.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.