USPTO Examiner HUMPHREY LOUISE WANG ZHIYING - Art Unit 1657

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18815386AUTOBIOTIC COMPOSITIONS AND METHOD FOR PROMOTING HEALTHY GUT MICROBIOMEAugust 2024June 2025Allow920NoNo
18196574METHOD FOR TREATING PARKINSON’S DISEASE BY USING PARABACTEROIDES GOLDSTEINIIMay 2023October 2024Abandon1810NoNo
17820638Device and a Method for Immobilization of Proteins, Enzymes or CellsAugust 2022October 2025Abandon3701NoNo
17792176MYCELIUM MATERIALS, AND METHODS FOR PRODUCTION THEREOFJuly 2022October 2025Abandon3901NoNo
17680201SPECTRAL INTENSITY RATIO (SIR) ANALYSIS FOR RAPID LIVE MICROBIAL ENUMERATIONFebruary 2022March 2025Abandon3701NoNo
17671463METHODS AND KITS FOR PRODUCING A FIBRIN MATRIXFebruary 2022May 2025Abandon3910NoNo
17633064COMPOSITIONS OF PROBIOTICS AND BIOMASS AND METHODS FOR PROMOTING HEALTH IN A SUBJECTFebruary 2022January 2025Abandon3601NoNo
17560432HEMOSTATIC COMPOSITIONS AND METHODS OF MAKING THEREOFDecember 2021October 2025Abandon4620NoNo
17596346CARBON COMPOUND PRODUCTION IN PHOTOSYNTHETIC MICROORGANISMSDecember 2021November 2024Abandon3501NoNo
17530517COMPOSITIONS COMPRISING BACTERIAL STRAINSNovember 2021May 2025Abandon4210NoNo
17609931METHOD OF EXTRACTING PROTEIN FROM SEA LETTUCENovember 2021January 2025Abandon3810NoNo
17440064METHOD FOR PRODUCING CARBON-BASED PRODUCTS FROM SECONDARY RAW MATERIALS CONTAINING PH REGULATORSOctober 2021January 2025Abandon4001NoNo
17473910METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELDSeptember 2021October 2025Allow4920NoNo
17432929MATE AND SEPARATE: A CONVENIENT AND GENERAL METHOD FOR THE SEPARATION AND PURIFICATION OF TARGET MOLECULES FROM BIOLOGICAL MEDIA BY PHASE TRANSITION OF PEGYLATED RECOGNITION AGENTS.August 2021November 2024Abandon3901NoNo
17406339COMPOSITIONS COMPRISING BACTERIAL STRAINSAugust 2021May 2025Abandon4511NoNo
17428375TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION WITH SPECIFIC CARBOHYDRATE DIETAugust 2021October 2024Abandon3910NoNo
17421721Food Supplement For Improving Sports PerformanceJuly 2021December 2024Abandon4211NoNo
17294065METHOD FOR IDENTIFYING 2'O-METHYLATION MODIFICATION IN RNA MOLECULE, AND APPLICATION THEREOFMay 2021January 2025Abandon4511NoNo
17235450CELL-FREE METABOLIC PATHWAY OPTIMIZATION THROUGH REMOVAL OF SELECT PROTEINSApril 2021October 2025Abandon5331NoNo
17284744CRISPR SYSTEM FOR GENOME EDITINGApril 2021August 2024Abandon4101NoNo
17224596RECOMBINANT MICROORGANISM INCLUDING GENETIC MODIFICATION THAT INCREASES ACTIVITY OF NITRIC OXIDE REDUCTASE AND METHOD OF REDUCING CONCENTRATION OF NITRIC OXIDE IN SAMPLE BY USING THE SAMEApril 2021October 2025Allow5551YesNo
17268721SYNTHESIS OF DNA WITH IMPROVED YIELDFebruary 2021November 2025Abandon5721NoNo
17160181MANUFACTURING METHOD OF HIGH-EFFICIENCY PLANT COMPOSITE TYPE BACTERIOSTATIC DEODORANT BASED ON HQ22 BEAN EXTRACTJanuary 2021October 2022Abandon2010NoNo
17114220MANUFACTURING OR ONSIDE INSTALLATION OF COMPOSITIONS WITH METHODS, SYSTEMS TO ADDRESS ECOLOGICAL AND ECONOMICAL CONCERNS OF THE AQUACULTURE INDUSTRYDecember 2020October 2024Abandon4601NoNo
17026359GENOME-WIDE RATIONALLY-DESIGNED MUTATIONS LEADING TO ENHANCED TYROSINE PRODUCTION IN S. CEREVISIAESeptember 2020February 2023Abandon2901NoNo
16980582A HEPATOCYTE-MIMICKING ANTIDOTE FOR ALCOHOL INTOXICATIONSeptember 2020February 2023Abandon2911NoNo
16926423NOVEL APPLICATIONS OF PULSED ELECTRIC FIELD AND E-BEAM TECHNOLOGYJuly 2020January 2023Abandon3010NoNo
16769402METHODS AND PRODUCTS FOR BIODEGRADATION OF WASTEJune 2020November 2022Abandon2901NoNo
16754247PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTSApril 2020February 2023Abandon3411NoNo
16653452White Blood Cell Analysis System and MethodOctober 2019April 2023Abandon4210NoNo
16467529APPARATUS, SYSTEMS, AND METHODS FOR VASCULAR TISSUE PERFUSIONJune 2019February 2023Abandon4501NoNo
16389577Cannabinoid Production by Synthetic In Vivo MeansApril 2019February 2021Abandon2201NoNo
16368808LYTIC PEPTIDE BIOSENSOR AND METHODS OF MAKING AND USING THE SAMEMarch 2019November 2019Abandon700NoNo
16326609LIVER PRESERVATION METHOD AND OPERATION METHODFebruary 2019January 2023Abandon4601NoNo
16321880Method for Producing SoyasaponinsJanuary 2019January 2021Abandon2301NoNo
16197435METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEMNovember 2018November 2020Abandon2401NoNo
16099889Universal Calibration Method for Assaying Enzymatic InhibitorsNovember 2018August 2022Abandon4631NoNo
16090867BIFIDOBACTERIA FOR INCREASING LEAN BODY MASSOctober 2018November 2020Abandon2510NoNo
16141687PREBIOTIC BACTERIOPHAGE CONTAINING COMPOSITION FOR TREATMENT OF GASTROINTESTINAL INFLAMMATIONSeptember 2018August 2025Allow6071NoNo
16106138CENTRIFUGATION AND FILTRATION METHODS FOR CONCENTRATING MICROORGANISMSAugust 2018January 2021Abandon2810YesNo
16104549Probiotic SolutionAugust 2018November 2020Abandon2710NoNo
16101449COMPOSITES HAVING NOVEL ANTI-FOULING COMPONENTS AND METHODS OF MANUFATUREAugust 2018January 2021Abandon2901NoNo
16070779CULTURE MEDIUM FOR DETECTING ENTEROCOCCUS AND METHOD FOR DETECTING SAMEJuly 2018February 2021Abandon3110NoNo
16022429METAL-CHELATE COMPLEX HYDROGEN SULFIDE SCAVENGERSJune 2018November 2020Abandon2910NoNo
16015668Method of Increasing Probiotic Viability in Food ProductsJune 2018July 2021Abandon3720NoNo
15984576CONVERSION SYSTEM FOR BIOMASSMay 2018March 2019Abandon1010NoNo
15655537ADHERENT STROMAL CELLS DERIVED FROM PLACENTAS OF MULTIPLE DONORS AND USES THEREOFJuly 2017January 2023Abandon6040NoNo
15612459Compositions for the Restoration of a Fecal Microbiota and Methods for Making and Using ThemJune 2017June 2019Abandon2410YesNo
15501041DETECTION OF PROTEIN ARGININE DEMETHYLASE ACTIVITYFebruary 2017April 2020Abandon3911NoNo
15420060IN VITRO CELLULAR ANALYSISJanuary 2017November 2022Abandon6041NoNo
15325891METHOD FOR PRODUCING GAMMA-GLUTAMYLCYSTEINE AND GLUTATHIONEJanuary 2017August 2020Abandon4321NoNo
15317867SYSTEM AND METHODS FOR APPLYING CONTROLLED LOW-INTENSITY ULTRASOUND TO A CELL CULTUREDecember 2016March 2019Abandon2701NoNo
15369105METHODS AND COMPOSITIONS FOR DIAGNOSING DISEASEDecember 2016May 2018Abandon1720NoNo
15309994Method of Producing Organic CompoundsNovember 2016March 2019Abandon2801NoNo
15342140ENZYME COMPOSITION FOR THERAPEUTIC MANAGEMENT OF MUSCLE SORENESSNovember 2016August 2020Abandon4531YesNo
15307506CELLULOSE-BASED BIOMASS JUICING METHOD AND GAS FUEL PREPARATION METHODOctober 2016March 2019Abandon2810NoNo
15288870COMPOSITIONS AND METHODS FOR INHIBITING PATHOGENIC GROWTHOctober 2016November 2018Abandon2610NoNo
15278126CELL CULTURE METHOD AND CELL CULTURE SYSTEMSeptember 2016April 2021Abandon5431YesNo
15273126ANIMAL CELL REGENERATION SPEED CONTROLLING METHOD AND ANIMAL CELL REGENERATION SPEED CONTROLLERSeptember 2016June 2020Abandon6021YesNo
15117742BIOMASS TRANSFORMATIONAugust 2016July 2020Abandon4721NoNo
15101991A METHOD FOR PREPARING A DAIRY PRODUCT HAVING A STABLE CONTENT OF GALACTO-OLIGOSACCHARIDE(S)June 2016January 2020Allow4321NoNo
15135222USE OF ORP FOR CHARACTERIZING STROKE PATIENTSApril 2016April 2020Abandon4821NoYes
14916255CULTURING METHOD FOR BACTERIA BELONGING TO GENUS COLLIMONAS AND STORAGE METHODMarch 2016March 2019Abandon3611NoNo
15058443MICROORGANISMS THAT EXTRACELLULARLY SECRETE LIPIDS AND METHODS OF PRODUCING LIPID AND LIPID PARTICLES ENCAPSULATING LIPIDS USING SAID MICROORGANISMSMarch 2016September 2018Allow3011YesNo
15013550FRACTIONATION AND SEPARATION OF LIGNOCELLULOSIC BIOMASS CARBOHYDRATES BY TWO STAGE STEAM PRETREATMENTFebruary 2016October 2018Allow3220YesNo
14847695METHODS AND USES OF MEDIASTINAL PLEURA TISSUE FOR VARIOUS STENT AND OTHER MEDICAL APPLICATIONSSeptember 2015February 2023Abandon6071YesNo
14397378METHODS FOR MODIFICATION OF TISSUESOctober 2014March 2019Abandon5222NoNo
14325040POLYPEPTIDES HAVING ANTIVIRAL ACTIVITY AND METHODS FOR USE THEREOFJuly 2014June 2015Allow1200NoNo
14300686METHOD OF CULTURING CELLSJune 2014July 2015Abandon1310NoNo
14270623HMGB1 AND ANTI-HMGB1 ANTIBODIES FOR THE PROGNOSTIC OF NEUROLOGICAL DISORDERSMay 2014June 2015Allow1400NoNo
14355108METHOD FOR ISOLATING CELLS AND BIOPARTICLESApril 2014February 2017Abandon3310NoNo
14096916REPLICATION DEFICIENT RECOMBINANT VIRUSES EXPRESSING ANTIGENS REGULATED BY TRANSCRIPTIONAL CONTROL ELEMENTS COMPRISING MULTIPLE ELEMENTSDecember 2013June 2015Allow1810NoNo
14052375METHOD OF INHIBITING METHANOGENESISNovember 2013February 2017Abandon4011NoNo
14075943Respiratory Syncytial Virus (RSV) Sequences For Protein Expression and VaccinesNovember 2013June 2015Allow1901NoNo
14073112MONITORING AND INHIBITING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BY MODULATING HMGB1 DEPENDENT TRIGGERING OF HIV-1 REPLICATION AND PERSISTENCENovember 2013June 2015Allow2001NoNo
14111790COMPOSITIONS FOR DETECTING AN INFECTION BY AN HIV-1 VIRUSOctober 2013June 2015Allow2010NoNo
14027495ORGAN ARREST, PROTECTION, PRESERVATION AND RECOVERYSeptember 2013July 2015Abandon2121NoNo
13900750USE OF KERATINOCYTES AS A BIOLOGICALLY ACTIVE SUBSTANCE IN THE TREATMENT OF WOUNDS, SUCH AS DIABETIC WOUNDS, OPTIONALLY IN COMBINATION WITH A DPP-4 INHIBITORMay 2013May 2017Abandon4841NoNo
13866060CHROMATOGRAPHY METHODApril 2013June 2015Allow2511NoNo
13856354SMALL ENZYME-CONTAINING GRANULESApril 2013August 2015Abandon2820NoNo
13688468INTRADERMAL INFLUENZA VACCINENovember 2012February 2017Abandon5120NoYes
13641590NANOZYMES, METHODS OF MAKING NANOZYMES, AND METHODS OF USING NANOZYMESOctober 2012May 2018Allow6021NoYes
13549211IDENTIFYING AND MEASURING RETICULOCYTESJuly 2012October 2014Allow2721YesNo
13520021HIGH THROUGHPUT CELL-BASED HPV IMMUNOASSAYS FOR DIAGNOSIS AND SCREENING OF HPV-ASSOCIATED CANCERSJune 2012May 2015Allow3531YesNo
13282006METHODS FOR REMOVING PLASMAOctober 2011July 2015Abandon4401NoNo
13269195Magnetic PigmentOctober 2011September 2016Abandon6020NoYes
13207905Treatment of Diabetes with Pancreatic Endocrine Precursor CellsAugust 2011May 2017Abandon6070NoYes
13185386NEUTRALIZING MOLECULES TO VIRAL ANTIGENSJuly 2011June 2015Allow4711NoNo
13028819NUCLEOSIDE-CONTAINING COMPOSITIONS AND METHODS FOR TREATING RED BLOOD CELLSFebruary 2011January 2017Abandon6031NoYes
12792259METHOD OF FILTERING PLATELETS TO REMOVE ANTIPLATELET AND ANTICOAGULANT AGENTSJune 2010January 2015Allow5521YesNo
12226648MAGNETIC RESONANCE-DETECTABLE, ULTRASOUND-DETECTABLE AND/OR RADIOPAQUE MICROCAPSULES AND USES THEREOFJuly 2009August 2015Abandon6031NoNo
12296413PROTEASE DETECTION PRODUCTNovember 2008July 2015Abandon6031NoNo
12230566Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cellsSeptember 2008October 2016Abandon6020YesYes
12140664METHOD OF TISSUE VASCULARIZATIONJune 2008December 2015Abandon6041NoYes
11917169Method For Cell CultureDecember 2007May 2016Abandon6020NoYes
11920782Protein-Immobilized membrane, method for immobilization of protein, enzyme-immobilized electrode, and biosensorNovember 2007February 2016Abandon6041NoNo
11708175ALTERNATE READING FRAME HEPATITIS C VIRUS PEPTIDES AND USES THEREOFFebruary 2007March 2010Allow3712YesNo
11640470Tissue control rods for sheet-based tissue engineeringDecember 2006July 2015Abandon6031YesNo
10577893HCV REPLICONS CONTAINING NS5B FROM GENETYPE 2BMay 2006September 2012Allow6001YesNo
11388135CHARGED LIPOPROTEIN COMPLEXES AND THEIR USESMarch 2006December 2011Allow6042YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner HUMPHREY, LOUISE WANG ZHIYING.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
7
Examiner Affirmed
5
(71.4%)
Examiner Reversed
2
(28.6%)
Reversal Percentile
44.2%
Lower than average

What This Means

With a 28.6% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
13
Allowed After Appeal Filing
4
(30.8%)
Not Allowed After Appeal Filing
9
(69.2%)
Filing Benefit Percentile
46.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 30.8% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner HUMPHREY, LOUISE WANG ZHIYING - Prosecution Strategy Guide

Executive Summary

Examiner HUMPHREY, LOUISE WANG ZHIYING works in Art Unit 1657 and has examined 103 patent applications in our dataset. With an allowance rate of 30.1%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 40 months.

Allowance Patterns

Examiner HUMPHREY, LOUISE WANG ZHIYING's allowance rate of 30.1% places them in the 4% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by HUMPHREY, LOUISE WANG ZHIYING receive 1.74 office actions before reaching final disposition. This places the examiner in the 37% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by HUMPHREY, LOUISE WANG ZHIYING is 40 months. This places the examiner in the 23% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +40.0% benefit to allowance rate for applications examined by HUMPHREY, LOUISE WANG ZHIYING. This interview benefit is in the 87% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 9.7% of applications are subsequently allowed. This success rate is in the 5% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 36.4% of cases where such amendments are filed. This entry rate is in the 55% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 100.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 70% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 41.7% of appeals filed. This is in the 8% percentile among all examiners. Of these withdrawals, 60.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner rarely withdraws rejections during the appeal process compared to other examiners. If you file an appeal, be prepared to fully prosecute it to a PTAB decision. Per MPEP § 1207, the examiner will prepare an Examiner's Answer maintaining the rejections.

Petition Practice

When applicants file petitions regarding this examiner's actions, 70.6% are granted (fully or in part). This grant rate is in the 77% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 8.7% of allowed cases (in the 92% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.