USPTO Art Unit 1681 Prosecution Statistics

Art Unit Information

Art Unit: 1681
Group: 1680
Tech Center: 1600
Total Cases: 2,058
Last Active: March 2025

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19082485LINKED LIGATIONMarch 2025May 2025Allow200NoNo
19070259METHODS AND SYSTEMS FOR DETECTING GENETIC VARIANTSMarch 2025April 2025Allow210NoNo
18958854SEQUENCING A TARGET SEQUENCE IN A CELLNovember 2024June 2025Allow610NoNo
18946611METHODS OF PREDICTING ENGRAFTMENT CAPABILITY OF DIFFERENTIATED NEURONAL PROGENITOR CELLSNovember 2024February 2025Allow300NoNo
18939315TEMPERATURE-SELECTABLE FRET CASSETTE SIGNALINGNovember 2024June 2025Allow811NoNo
18930072METHODS FOR MONITORING RESIDUAL DISEASEOctober 2024February 2025Allow1310YesNo
18911297COMPOSITION AND KIT FOR DETECTING MYCOPLASMAOctober 2024June 2025Allow810YesNo
18903582HIGH THROUGHPUT SCREENING ASSAY TO IDENTIFY DNA TOPOISOMERASE INHIBITORSOctober 2024January 2025Allow310NoNo
18900948METHOD, KIT AND SYSTEM FOR END LABELING OF NUCLEIC ACIDSSeptember 2024June 2025Allow811YesNo
18892086ASSAYS AND OTHER REACTIONS INVOLVING DROPLETSSeptember 2024May 2025Allow812YesNo
18889834DETECTING POLYNUCLEOTIDES WITH BARCODED OLIGONUCLEOTIDE PROBESSeptember 2024June 2025Allow920YesNo
18889404METHODS AND KITS USEFUL FOR DIAGNOSIS OF UROGENITAL CANCERSeptember 2024April 2025Allow701NoNo
18889399METHODS FOR ISOLATING TARGET ANALYTES FROM URINE SAMPLES USING ATPS AND MAGNETIC BEADSSeptember 2024April 2025Allow701NoNo
18887759DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERSSeptember 2024April 2025Allow721YesNo
18885331DETECTION OF METHYLATION STATUS OF A DNA SAMPLESeptember 2024May 2025Allow811YesNo
18827295MICROFLUIDICS SYSTEM, DEVICE, AND METHODS FOR PERFORMING RAPID POLYMERASE CHAIN REACTION (PCR) PROTOCOLSSeptember 2024April 2025Allow801NoNo
18820804MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOFAugust 2024March 2025Allow610NoNo
18813477METHODS AND SYSTEMS FOR DETECTING GENETIC VARIANTSAugust 2024February 2025Allow610NoNo
18812385METHODS AND SYSTEMS FOR DETECTING GENETIC VARIANTSAugust 2024February 2025Allow510NoNo
18807061DARK CYCLE SEQUENCINGAugust 2024February 2025Allow621NoNo
18803324COMPOSITION COMPRISING CELL ORIGINATION BARCODES FOR THE ANALYSIS OF BOTH GENOMIC DNA AND CDNA FROM THE SAME CELLAugust 2024October 2024Allow200NoNo
18776193DEVICES AND METHODS FOR ANALYZING BIOLOGICAL SAMPLESJuly 2024January 2025Allow610YesNo
18770298METHODS AND SYSTEMS FOR ANALYZING NUCLEIC ACID MOLECULESJuly 2024March 2025Allow810NoNo
18770271METHODS AND SYSTEMS FOR ANALYZING NUCLEIC ACID MOLECULESJuly 2024December 2024Allow510NoNo
18753625COMPOSITIONS AND METHODS FOR NUCLEIC ACID EXTENSIONJune 2024May 2025Abandon1001NoNo
18752431CAPTURING, CONCENTRATING, AND DETECTING MICROBES IN A SAMPLE USING MAGNETIC IONIC LIQUIDS AND RECOMBINASE POLYMERASE AMPLIFICATIONJune 2024June 2025Allow1110NoNo
18737828PROBE-BASED ANALYSIS OF NUCLEIC ACIDS AND PROTEINSJune 2024March 2025Abandon910NoNo
18737230SYSTEMS AND METHODS FOR SEQUENCING ERROR CORRECTION VIA DOUBLE STRAND PRESERVATIONJune 2024September 2024Allow410NoNo
18715913A METHOD OF CAPTURING CRISPR ENDONUCLEASE CLEAVAGE PRODUCTSJune 2024July 2025Allow1321YesNo
18679053METHOD FOR BARCODINGMay 2024September 2024Allow300YesNo
18677090SYSTEMS AND METHODS TO DETECT RARE MUTATIONS AND COPY NUMBER VARIATIONMay 2024February 2025Allow910NoNo
18677555COMPOSITION COMPRISING CELL ORIGINATION BARCODES FOR THE ANALYSIS OF BOTH PROTEIN AND NUCLEIC ACID FROM THE SAME CELLMay 2024August 2024Allow300YesNo
18675708LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCINGMay 2024May 2025Allow1210NoNo
18673376METHOD FOR SCREENING LACTOBACILLUS CASEI FERMENTATION AGENTMay 2024October 2024Allow510NoNo
18672154Adenosine triphosphatase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2) gene-based molecular marker for identifying chicken feed efficiency trait, and identification method and use thereofMay 2024March 2025Allow1010NoNo
18655106METHODS FOR PROCESSING NUCLEIC ACID SAMPLESMay 2024June 2025Abandon1320NoNo
18652923Method of Selectively Sequencing Amplicons in a Biological SampleMay 2024November 2024Allow700NoNo
18649324POLYNUCLEOTIDE SEQUENCE DETECTION METHODApril 2024March 2025Allow1100NoNo
18645232DETECTING MOLECULES IN TISSUESApril 2024December 2024Allow730NoNo
18642342DETECTABLE NUCLEOTIDE ANALOGUESApril 2024April 2025Allow1221NoNo
18639734CHROMOGENIC PEROXIDASE SUBSTRATESApril 2024April 2025Allow1210NoNo
18635474ULTRASENSITIVE MOLECULAR DETECTION VIA HYBRIDIZATION CHAIN REACTIONApril 2024January 2025Allow911NoNo
18630722SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELSApril 2024March 2025Allow1110NoNo
18629793KIT FOR DETECTING AFRICAN SWINE FEVER VIRUS (ASFV)April 2024August 2024Allow510NoNo
18625882METHODS AND SYSTEMS FOR ANALYZING NUCLEIC ACID MOLECULESApril 2024April 2025Allow1220NoNo
18618544POLYMERIC TANDEM DYES WITH LINKER GROUPSMarch 2024March 2025Allow1110NoNo
18616750METHODS FOR PROCESSING A NUCLEIC ACID SAMPLE AND COMPOSITIONS THEREOFMarch 2024December 2024Allow810YesNo
18613979SAFE SEQUENCING SYSTEMMarch 2024April 2025Abandon1320NoNo
17760099InDel MOLECULAR MARKER OF hisD GENE OF ULTRASONICALLY-MUTAGENIZED SALMONELLA TYPHIMURIUM AND USE THEREOFMarch 2024January 2025Abandon3001NoNo
18605587KOMPETITIVE ALLELE-SPECIFIC POLYMERASE CHAIN REACTION MOLECULAR MARKERS CLOSELY LINKED WITH COTTON FIBRE LENGTH QUANTITATIVE TRAIT LOCUS AND APPLICATIONS THEREOFMarch 2024April 2025Abandon1320NoNo
18593787METHODS FOR ANALYZING BIOLOGICAL SAMPLES IN A FLUIDIC DEVICE COMPRISING GENERATING A POLYMER MATRIX FROM PRECURSORS AT SPECIFIC LOCATIONS COMPRISING BIOLOGICAL COMPONENTSMarch 2024July 2024Allow410YesNo
18591066METHODS AND COMPOSITIONS FOR THE EXTRACTION AND AMPLIFICATION OF NUCLEIC ACID FROM A SAMPLEFebruary 2024July 2025Abandon1611NoNo
18586420SIGNAL BOOST ASSAY PERFORMED IN DROPLETSFebruary 2024January 2025Abandon1111NoNo
18442644COMPOSITIONS AND METHODS FOR DETECTING OR QUANTIFYING HUMAN PARAINFLUENZA VIRUS 2February 2024June 2025Allow1610NoNo
18442591COMPOSITIONS AND METHODS FOR DETECTING OR QUANTIFYING HUMAN PARAINFLUENZA VIRUS 4February 2024June 2025Allow1620NoNo
18439062CLEAVABLE DISULFIDE LINKERS AND USES THEREOFFebruary 2024October 2024Allow810NoNo
18437399SYSTEM AND SELF-METERING CARTRIDGES FOR POINT OF CARE BIOASSAYSFebruary 2024May 2025Allow1511NoNo
18438351DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERSFebruary 2024October 2024Allow810NoNo
18436754METHODS FOR GENOME ASSEMBLY AND HAPLOTYPE PHASINGFebruary 2024June 2025Allow1610NoNo
18434179Method for Detecting a Mutation in a Microsatellite SequenceFebruary 2024April 2025Allow1421YesNo
18430247QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNAFebruary 2024June 2025Allow1620NoNo
18429051METHODS AND SYSTEMS FOR SEQUENCING POLYNUCLEOTIDESJanuary 2024April 2025Allow1520YesNo
18426665SYSTEMS AND METHODS TO DETECT RARE MUTATIONS AND COPY NUMBER VARIATIONJanuary 2024January 2025Allow1110NoNo
18424417CYANINE DERIVATIVES AND RELATED USESJanuary 2024April 2025Allow1521NoNo
18423259PROTECTED DYE-LABELED REAGENTSJanuary 2024March 2025Allow1410NoNo
18290827Colorimetric sensing with reconfigurable chiral plasmonic structures and a method for detecting analytes in samples using the sameJanuary 2024April 2025Allow1520NoNo
18410793LINKERS AND METHODS FOR OPTICAL DETECTION AND SEQUENCINGJanuary 2024March 2025Allow1420NoNo
18409178SINGLE NUCLEOTIDE DETECTION METHOD AND ASSOCIATED PROBESJanuary 2024April 2025Allow1511NoNo
18405775OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAMEJanuary 2024May 2025Abandon1710NoNo
18576506METHOD FOR COLD PLASMA INDUCED CELL DEATH IN BREAST CANCER CELLS BY 8-OXOG MODIFICATION AND DEGRADATION OF HISTONE MRNAJanuary 2024May 2025Allow1620NoNo
18392743METHODS AND SYSTEMS FOR NUCLEIC ACID ANALYSISDecember 2023April 2025Abandon1620NoNo
18569594SPATIAL ANALYSIS OF A PLANAR BIOLOGICAL SAMPLEDecember 2023December 2024Allow1210NoNo
18536784Method to Screen For a Mutant Within a Population of Organisms By Applying a Pooling and Splitting ApproachDecember 2023June 2025Allow1801NoNo
18536935DIGITAL ANALYTE ANALYSISDecember 2023December 2024Allow1221YesNo
18535267METHODS FOR NUCLEIC ACID DETECTIONDecember 2023April 2025Abandon1610NoNo
18527896Single Cell Nucleic Acid Detection and AnalysisDecember 2023June 2025Allow1940NoNo
18522886NUCLEOTIDE ANALOGUESNovember 2023December 2024Allow1221NoNo
18520654Single Cell Nucleic Acid Detection and AnalysisNovember 2023April 2025Allow1710NoNo
18518124METHOD AND SYSTEM FOR THERMALLY CONTROLLING A CHEMICAL REACTION IN DROPLETSNovember 2023May 2025Abandon1820NoNo
18514235SYSTEMS AND METHODS FOR ENCAPSULATION AND MULTI-STEP PROCESSING OF BIOLOGICAL SAMPLESNovember 2023May 2025Allow1810NoNo
18509322PRIMER GROUP FOR SIMULTANEOUS DETECTION OF 15 PORCINE PATHOGENS THROUGH HIGH-THROUGHPUT TARGETED AMPLICON SEQUENCING AND USE THEREOFNovember 2023December 2024Allow1321YesNo
18507776SAFE SEQUENCING SYSTEMNovember 2023January 2025Allow1430NoNo
18560444METHODS OF MONITORING IN VITRO TRANSCRIPTION OF MRNA AND/OR POST-IN VITRO TRANSCRIPTION PROCESSESNovember 2023May 2025Allow1811YesNo
18505697LISTERIA-MONOCYTOGENES DETECTION METHODNovember 2023July 2024Allow800NoNo
18504925PREPARATION OF OLIGO CONJUGATESNovember 2023December 2024Abandon1310NoNo
18386975EMULSION COMPOSITIONS AND METHODS OF THEIR USENovember 2023December 2024Allow1330YesNo
18499129CATALYTIC DE-CROSSLINKING OF SAMPLES FOR IN SITU ANALYSISOctober 2023January 2025Allow1511YesNo
18384527COMPOSITIONS AND METHODS FOR SAMPLE PROCESSINGOctober 2023May 2025Abandon1810NoNo
18494425SYNTHESIS OF DNA MOLECULES IN IN VITRO ENZYMATIC SYSTEMSOctober 2023June 2025Allow2021NoNo
18288370Amplification of Single Stranded DNAOctober 2023January 2025Allow1520NoNo
18492120FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOFOctober 2023March 2025Allow1730NoNo
18381371MDA USING BEAD OLIGONUCLEOTIDEOctober 2023October 2024Allow1210NoNo
18488801NUCLEOTIDES WITH A 3' AOM BLOCKING GROUPOctober 2023October 2024Allow1210NoNo
18483309PHOTOACTIVE MACROMOLECULES AND USES THEREOFOctober 2023January 2025Allow1620NoNo
18481021METHODS OF PREPARING NUCLEIC ACIDS FOR SEQUENCINGOctober 2023March 2025Allow1820NoNo
18480799SOYASAPONIN-RELATED KOMPETITIVE ALLELE-SPECIFIC POLYMERASE CHAIN REACTION MARKERS AND APPLICATION THEREOFOctober 2023February 2025Allow1620NoNo
18480850METHODS AND SYSTEMS FOR SENSITIVE AND MULTIPLEXED ANALYSIS OF BIOLOGICAL SAMPLES USING CLEAVABLE FLUORESCENT STREPTAVIDIN AND ANTI-HAPTEN ANTIBODIESOctober 2023March 2025Allow1720NoNo
18374953REMOTE AUTONOMOUS ENVIRONMENTAL DNA SAMPLER AND ANALYZERSeptember 2023November 2024Allow1320NoNo
18375440FRET-LABELED COMPOUNDS AND USES THEREFORSeptember 2023June 2025Allow2120NoNo
18367638METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDESSeptember 2023October 2024Abandon1321YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1681.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
22
Examiner Affirmed
9
(40.9%)
Examiner Reversed
13
(59.1%)
Reversal Percentile
96.1%
Higher than average

What This Means

With a 59.1% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
173
Allowed After Appeal Filing
71
(41.0%)
Not Allowed After Appeal Filing
102
(59.0%)
Filing Benefit Percentile
86.7%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 41.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the top 25% across the USPTO, indicating that filing appeals is particularly effective here. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Strategic Recommendations

✓ Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

✓ Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Art Unit 1681 - Prosecution Statistics Summary

Executive Summary

Art Unit 1681 is part of Group 1680 in Technology Center 1600. This art unit has examined 2,058 patent applications in our dataset, with an overall allowance rate of 89.7%. Applications typically reach final disposition in approximately 35 months.

Comparative Analysis

Art Unit 1681's allowance rate of 89.7% places it in the 90% percentile among all USPTO art units. This art unit has a significantly higher allowance rate than most art units at the USPTO.

Prosecution Patterns

Applications in Art Unit 1681 receive an average of 2.23 office actions before reaching final disposition (in the 80% percentile). The median prosecution time is 35 months (in the 19% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more favorable examination environment compared to the USPTO average.
  • With more office actions than average, plan for multiple rounds of prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.