USPTO Examiner WOOLWINE SAMUEL C - Art Unit 1681

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18885331DETECTION OF METHYLATION STATUS OF A DNA SAMPLESeptember 2024May 2025Allow811YesNo
18673376METHOD FOR SCREENING LACTOBACILLUS CASEI FERMENTATION AGENTMay 2024October 2024Allow510NoNo
18576506METHOD FOR COLD PLASMA INDUCED CELL DEATH IN BREAST CANCER CELLS BY 8-OXOG MODIFICATION AND DEGRADATION OF HISTONE MRNAJanuary 2024May 2025Allow1620NoNo
18330279METHODS FOR ASSEMBLING AND READING NUCLEIC ACID SEQUENCES FROM MIXED POPULATIONSJune 2023October 2024Abandon1620NoNo
18173060SPECIFIC DNA FRAGMENT OF FEMALE ACIPENSER DABRYANUS AND METHOD FOR IDENTIFYING THE SEX OF ACIPENSER DABRYANUSFebruary 2023May 2024Allow2720NoNo
17293412ELECTRONIC DETECTION OF NUCLEIC ACID STRUCTURESeptember 2022July 2025Allow5000NoNo
17864913LABELING STRATEGY FOR USE IN DNA SEQUENCING TO FACILITATE ASSEMBLY OF SEQUENCE READS INTO LONGER FRAGMENTS OF A GENOMEJuly 2022May 2025Allow3410NoNo
17824215METHODS AND PROBES FOR PERFORMING PCR WITH MELT ANALYSIS FOR INCREASED MULTIPLEXINGMay 2022January 2025Allow3200NoNo
17735904Estimating Tumor Purity From Single SamplesMay 2022September 2024Allow2910YesNo
17731006Nucleic Acid TaggantsApril 2022February 2025Allow3320YesNo
17728463METHODS FOR STANDARDIZED SEQUENCING OF NUCLEIC ACIDS AND USES THEREOFApril 2022July 2025Allow3810NoNo
17700373COMPOSITIONS AND METHODS FOR MOLECULAR LABELINGMarch 2022September 2024Allow3060NoNo
17651225NANOPORE-BASED POLYMER ANALYSIS WITH MUTUALLY-QUENCHING FLUORESCENT LABELSFebruary 2022November 2024Abandon3310NoNo
17630004POLYNUCLEOTIDES FOR THE AMPLIFICATION AND DETECTION OF NEISSERIA GONORRHOEAEJanuary 2022April 2025Abandon3810NoNo
17575914DETECTING NUCLEIC ACIDJanuary 2022December 2024Abandon3510NoNo
17568077METHODS AND COMPOSITIONS FOR STABILIZING NUCLEIC ACID-NUCLEOTIDE-POLYMERASE COMPLEXESJanuary 2022May 2025Allow4010NoNo
17562346Small RNA Capture, Detection and QuantificationDecember 2021May 2025Abandon4110NoNo
17547920DEVICES, SYSTEMS AND METHODS FOR BIOMARKER ANALYSISDecember 2021December 2023Abandon2430YesNo
17531270SYSTEMS AND PROCESSES FOR DISTINGUISHING PATHOGENIC AND NON-PATHOGENIC SEQUENCES FROM SPECIMENSNovember 2021April 2025Allow4110NoNo
17529082COMPOSITIONS AND METHODS FOR MOLECULAR LABELINGNovember 2021June 2024Allow3150NoNo
17599423Shape-Responsive NanostructuresSeptember 2021January 2025Allow4010NoNo
17470828PCR TUBE, APPARATUS FOR PCR INCLUDING THE SAME AND PCR METHOD USING THE SAMESeptember 2021November 2024Allow3810NoNo
17458995NUCLEIC ACID ANALYSIS BY JOINING BARCODED POLYNUCLEOTIDE PROBESAugust 2021January 2025Allow4110NoNo
17434293AN IMPROVED METHOD OF PREPARING CLINICAL SAMPLES FOR NUCLEIC ACID AMPLIFICATIONAugust 2021May 2025Allow4410NoNo
17397280UNIVERSAL SANGER SEQUENCING FROM NEXT-GEN SEQUENCING AMPLICONSAugust 2021November 2024Allow3920NoNo
17427266MULTIPLEX PCR METHOD USING APTAMERJuly 2021March 2025Abandon4310NoNo
17369834ANALYSIS OF A POLYNUCLEOTIDE VIA A NANOPORE SYSTEMJuly 2021March 2025Allow4410NoNo
17369796SEQUENCES FOR DETECTION AND IDENTIFICATION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) OF MREJ TYPE XXIJuly 2021March 2025Abandon4420NoNo
17356402METHOD FOR DETECTING CHIKUNGUNYA VIRUSJune 2021February 2025Allow4430YesNo
17346077NUCLEIC ACID ASSAYS USING CLICK CHEMISTRY BIOCONJUGATIONJune 2021September 2024Allow6010NoNo
17336055OLIGONUCLEOTIDES AND BEADS FOR 5 PRIME GENE EXPRESSION ASSAYJune 2021July 2024Allow3811NoNo
17316416METHOD FOR LABEL-FREE SINGLE-MOLECULE DNA SEQUENCING AND DEVICE FOR IMPLEMENTING SAMEMay 2021December 2024Abandon4310NoNo
17289499Compositions and Methods for Discriminating Infectious from Non-Infectious CNS DisordersApril 2021November 2024Abandon4201NoNo
17236889TERMINAL FUNCTIONALIZATION OF TARGET MOLECULES FOR SEQUENCINGApril 2021December 2024Abandon4420NoNo
17283968CATALYTIC BIOMOLECULE ACTIVITY RECORDING INTO DNA SEQUENCEApril 2021September 2024Allow4210NoNo
17126693METHOD OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDSDecember 2020September 2024Allow4541NoNo
17120518DETECTING CHOLANGIOCARCINOMADecember 2020August 2024Allow4440YesNo
17070190Methods for Making Nucleotide Probes for Sequencing and SynthesisOctober 2020August 2024Allow4621NoNo
17046552DNA-TAGGED METHANOL RESPONSIVE POLYMER FOR SINGLE-STRANDED NUCLEIC ACID PRODUCTIONOctober 2020December 2023Allow3830NoNo
17036401DETERMINISTIC BARCODING FOR SPATIAL OMICS SEQUENCINGSeptember 2020July 2024Allow4631NoNo
16979481METHODS OF SEQUENCING NUCLEIC ACIDS AND ERROR CORRECTION OF SEQUENCE READSSeptember 2020August 2024Allow4740NoNo
16970318METHODS AND COMPOSITIONS FOR RICKETTSIACEAE DETECTIONAugust 2020April 2025Abandon5631NoNo
16964386HYBRIDIZATION CHAIN REACTION-BASED METHOD FOR AMPLIFYING IMMUNOSIGNALSJuly 2020November 2024Allow5230NoNo
16869481METHODS AND COMPOSITIONS FOR NUCLEIC ACID DETECTIONMay 2020May 2025Abandon6041NoNo
16628828HIGH-COVERAGE AND ULTRA-ACCURATE IMMUNE REPERTOIRE SEQUENCING USING MOLECULAR IDENTIFIERSJanuary 2020February 2025Abandon6041YesNo
16596587SIMULTANEOUS QUANTIFICATION OF A PLURALITY OF PROTEINS IN A USER-DEFINED REGION OF A CROSS-SECTIONED TISSUEOctober 2019June 2025Allow6051YesNo
16444619METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLINGJune 2019August 2024Allow6041YesNo
16347387METHOD FOR DETERMINING A HEAD AND NECK SQUAMOUS CELL CARCINOMAMay 2019March 2025Allow6051YesNo
15785680Low Sequence Bias Single-Stranded DNA LigationOctober 2017December 2019Allow2610NoNo
15587944DETECTING NUCLEIC ACIDMay 2017December 2019Allow3110NoNo
15442864DNA SEQUENCING AND PROCESSINGFebruary 2017August 2019Allow3000YesNo
15285421Compositions And Methods For Immunodominant AntigensOctober 2016August 2018Allow2300NoNo
15271269REAL-TIME PCR POINT MUTATION ASSAYS FOR DETECTING HIV - 1 RESISTANCE TO ANTIVIRAL DRUGSSeptember 2016September 2019Allow3521YesNo
15056475COMBINED THERMAL DEVICES FOR THERMAL CYCLINGFebruary 2016November 2018Allow3310NoNo
14931716EXOSOMES AND MICROVESICLES IN INTESTINAL LUMINAL FLUIDS AND STOOL AND USE OF SAME FOR THE ASSESSMENT OF INFLAMMATORY BOWEL DISEASENovember 2015December 2018Allow3711NoNo
14765782METHOD FOR MEASURING BONE LOSS RATEAugust 2015February 2018Allow3020NoNo
14702628METHODS AND GENOTYPING PANELS FOR DETECTING ALLELES, GENOMES, AND TRANSCRIPTOMESMay 2015January 2018Allow3200NoNo
14395239METHODS FOR REAL-TIME SAMPLING OF REACTION PRODUCTSOctober 2014October 2017Allow3611NoNo
14512694Digital AmplificationOctober 2014January 2018Allow3911NoNo
14472155SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING APTAMERS OR NUCLEIC ACID SEQUENCES FOR USE THEREINAugust 2014June 2016Allow2210NoNo
14036527DOUBLE STRANDED LINEAR NUCLEIC ACID PROBESeptember 2013March 2016Allow3010YesNo
13748380DETECTION, IDENTIFICATION AND DIFFERENTIATION OF EUBACTERIAL TAXA USING A HYBRIDIZATION ASSAYJanuary 2013October 2015Allow3320NoNo
13665566NOVEL MIXTURES FOR ASSAYING NUCLEIC ACID, NOVEL METHOD OF ASSAYING NUCLEIC ACID WITH THE USE OF THE SAME AND NUCLEIC ACID PROBE TO BE USED THEREFOROctober 2012October 2016Allow4820NoYes
13466997METHODS, COMPOSITIONS AND KITS FOR DETECTION AND ANALYSIS OF ANTIBIOTIC-RESISTANT BACTERIAMay 2012June 2013Allow1310YesNo
13389927STAPHYLOCOCCUS DETECTION ASSAYSApril 2012February 2016Allow4811NoNo
13442514DEHALOGENASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEMApril 2012November 2015Allow4330NoYes
13436465NUCLEIC ACID SEQUENCING TECHNIQUE USING A PH-SENSING AGENTMarch 2012February 2016Allow4721YesNo
13412984METHOD FOR DETECTING AND QUANTIFYING RARE MUTATIONS/POLYMORPHISMSMarch 2012February 2016Allow4830YesNo
13399543COMBINATORIAL AFFINITY SELECTIONFebruary 2012June 2014Allow2820NoNo
13229111DETECTION OF RNA-INTERACTING REGIONS IN DNASeptember 2011July 2015Allow4711NoNo
13229598METHODS, COMPOSITIONS AND KITS FOR DETECTION AND ANALYSIS OF ANTIBIOTIC-RESISTANT BACTERIASeptember 2011March 2015Allow4210NoNo
13205496METHODS, COMPOSITIONS AND KITS FOR DETECTION AND ANALYSIS OF ANTIBIOTIC-RESISTANT BACTERIAAugust 2011June 2013Allow2220YesNo
13178807METHODS, COMPOSITIONS AND KITS FOR DETECTION AND ANALYSIS OF ANTIBIOTIC-RESISTANT BACTERIAJuly 2011September 2012Allow1410NoNo
12997479EIF2GAMMA GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIESMay 2011November 2017Allow6040YesYes
13071105Digital AmplificationMarch 2011July 2014Allow3931NoNo
13046186PARASITE DETECTION VIA ENDOSYMBIONT DETECTIONMarch 2011May 2017Allow6061YesNo
12966583COMBINED THERMAL DEVICES FOR THERMAL CYCLINGDecember 2010April 2013Allow2810NoNo
12945407METHOD FOR THE IDENTIFICATION AND QUANTIFICATION OF MICROORGANISMS USEFUL IN BIOMINING PROCESSESNovember 2010March 2013Allow2810NoNo
12742908METHODS AND SYSTEMS FOR BIOLOGICAL SAMPLE COLLECTION AND ANALYSISSeptember 2010March 2014Allow4621NoNo
12870568METHOD FOR DETECTING AN INDIVIDUAL WHO IS AFFLICTED WITH OR A CARRIER FOR VAN BUCHEM'S DISEASEAugust 2010September 2011Allow1310NoNo
12522480SLCO1B3 GENOTYPEAugust 2010May 2018Allow6080YesNo
12854619SPECIFIC DOUBLE-STRANDED PROBES FOR HOMOGENEOUS DETECTION OF NUCLEIC ACID AND THEIR APPLICATION METHODSAugust 2010June 2015Allow5950YesYes
12814199METHODS, COMPOSITIONS AND KITS FOR DETECTION AND ANALYSIS OF ANTIBIOTIC-RESISTANT BACTERIAJune 2010April 2013Allow3410NoNo
12771042NON-TARGET AMPLIFICATION METHOD FOR DETECTION OF RNA SPLICE-FORMS IN A SAMPLEApril 2010June 2017Allow6081NoNo
12738413METHOD OF NUCLEIC ACID AMPLIFICATION AND MEASURING REAGENT AND REAGENT KIT THEREFORApril 2010June 2013Allow3820YesNo
12677189NUCLEIC ACID DETECTION METHOD AND NUCLEIC ACID DETECTION KITMarch 2010March 2015Allow6031NoNo
12706472PCR METHODS FOR CHARACTERIZING THE 5' UNTRANSLATED REGION OF THE FMR1 AND FMR2 GENESFebruary 2010October 2013Allow4421NoNo
12700475REDUCING NON-TARGET NUCLEIC ACID DEPENDENT AMPLIFICATIONS: AMPLIFYING REPETITIVE NUCLEIC ACID SEQUENCESFebruary 2010June 2011Allow1711NoNo
12683906DEHALOGENASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEMJanuary 2010December 2011Allow2311YesNo
12617368DIGITAL AMPLIFICATIONNovember 2009December 2010Allow1310NoNo
12614844MICRO VALVE APPARATUS USING MICRO BEAD AND METHOD FOR CONTROLLING THE SAMENovember 2009April 2012Allow2920NoNo
12551991FUNCTIONALIZED FLUORESCENT NANOCRYSTAL DETECTION SYSTEMSeptember 2009March 2012Allow3120YesNo
12536269NANOSCALE SENSORSAugust 2009February 2012Allow3101YesNo
12458702ANNEALING CONTROL PRIMER AND ITS USESJuly 2009October 2011Allow2720NoNo
12504429BIOMARKERS FOR RENAL DISEASEJuly 2009November 2012Allow4011YesNo
12498183TIVOZANIB RESPONSE PREDICTIONJuly 2009August 2009Allow200NoNo
12496390METHOD FOR DETECTING AND QUANTIFYING RARE MUTATIONS/POLYMORPHISMSJuly 2009December 2011Allow3010NoNo
12439515DNA FRAGMENT USED AS ATTACHED TO 5' END OF PRIMER USED IN NUCLEIC ACID AMPLIFICATION REACTION AND USE OF DNA FRAGMENTFebruary 2009August 2011Abandon3031NoNo
12394993SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING APTAMERS OR NUCLEIC ACID SEQUENCES FOR USE THEREINFebruary 2009November 2011Allow3211YesNo
12357995UNIFORM FRAGMENTATION OF DNA USING BINDING PROTEINSJanuary 2009April 2012Allow3930YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner WOOLWINE, SAMUEL C.

Strategic Value of Filing an Appeal

Total Appeal Filings
15
Allowed After Appeal Filing
6
(40.0%)
Not Allowed After Appeal Filing
9
(60.0%)
Filing Benefit Percentile
62.7%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 40.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner WOOLWINE, SAMUEL C - Prosecution Strategy Guide

Executive Summary

Examiner WOOLWINE, SAMUEL C works in Art Unit 1681 and has examined 169 patent applications in our dataset. With an allowance rate of 89.3%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 40 months.

Allowance Patterns

Examiner WOOLWINE, SAMUEL C's allowance rate of 89.3% places them in the 69% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by WOOLWINE, SAMUEL C receive 2.33 office actions before reaching final disposition. This places the examiner in the 80% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by WOOLWINE, SAMUEL C is 40 months. This places the examiner in the 7% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +5.2% benefit to allowance rate for applications examined by WOOLWINE, SAMUEL C. This interview benefit is in the 30% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 29.6% of applications are subsequently allowed. This success rate is in the 48% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 45.5% of cases where such amendments are filed. This entry rate is in the 63% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 86% percentile among all examiners. Of these withdrawals, 93.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 65.2% are granted (fully or in part). This grant rate is in the 82% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 20.7% of allowed cases (in the 99% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 15.9% of allowed cases (in the 91% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.