USPTO Art Unit 1652 Prosecution Statistics

Art Unit Information

Art Unit: 1652
Group: 1650
Tech Center: 1600
Total Cases: 16,692
Last Active: November 2024

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18963644BACILLUS PROTEOLYTICUS CWJ-2-GJ AND APPLICATION THEREOFNovember 2024April 2025Allow410YesNo
18940031Hyaluronidase Enzyme Formulations for High Volume AdministrationNovember 2024July 2025Allow811YesNo
18940001Hyaluronidase Enzyme Formulations for High Volume AdministrationNovember 2024June 2025Allow811YesNo
18935987FOOD COMPOSITION CONTAINING NOVEL ALDEHYDE DEHYDROGENASE FOR IMPROVING MEMORY AND COGNITIVE FUNCTIONNovember 2024April 2025Allow510NoNo
18933327CARBONYL REDUCTASE MUTANT AND ITS APPLICATIONOctober 2024March 2025Allow510NoNo
18859487ALDITOL OXIDASE AND APPLICATION THEREOFOctober 2024February 2025Allow400NoNo
18886923ELECTRO-RESPONSIVE SILK FIBROIN MATERIAL, ELECTRO-RESPONSIVE SILK FIBROIN MICRONEEDLE, INSULIN MICRONEEDLE PATCH HAVING ELECTRO-RESPONSIVE SILK FIBROIN AND PREPARATION METHOD THEREFOR, AND TRANSDERMAL DRUG DELIVERY DEVICESeptember 2024April 2025Allow710NoNo
18846061ENZYMATIC METHOD FOR THE PRODUCTION OF L-GLUFOSINATE P-ESTERSSeptember 2024June 2025Allow910YesNo
18882341CELL WALL HYDROLASES TARGETING C. ACNESSeptember 2024April 2025Allow711YesNo
18825195GENETIC ENGINEERING BACTERIUM FOR DE NOVO SYNTHESIS OF CIS,CIS-MUCONIC ACID BY TAKING GLUCOSE AS SUBSTRATE AND APPLICATIONS THEREOFSeptember 2024April 2025Allow820YesNo
18814865DEAMINASES AND VARIANTS THEREOF FOR USE IN BASE EDITINGAugust 2024March 2025Allow611NoNo
18781694RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USEJuly 2024April 2025Allow911NoNo
18770533MICROORGANISMS AND METHODS FOR THE CONTINUOUS PRODUCTION OF FATTY ACIDS, FATTY ALCOHOLS, AND CULTURED PROTEIN FROM C1 SUBSTRATESJuly 2024June 2025Abandon1111NoNo
18767461SYSTEM AND METHOD FOR CO2 HYDROGENATION USING MULTI-ENZYME IMMOBILIZATION ON MODIFIED METAL-ORGANIC FRAMEWORK (MOF)July 2024February 2025Allow811YesNo
18767086SUBTERRANEAN WATER BARRIERJuly 2024February 2025Allow711NoNo
18762259COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSIONJuly 2024April 2025Allow1011NoNo
18749788USE OF MUTANT OF IMMUNOGLOBULIN DEGRADING ENZYME IDEEJune 2024March 2025Allow911NoNo
18717423LACTIPLANTIBACILLUS PLANTARUM STRAIN FOR ALLEVIATING HYPERURICEMIA AND COMBINATION AND USE THEREOFJune 2024May 2025Allow1110NoNo
18674430INTEGRATED GAS FERMENTATION AND CARBON BLACK PROCESSESMay 2024June 2025Allow1221NoNo
18674362INTEGRATED GAS FERMENTATIONMay 2024March 2025Allow911YesNo
18672113VERSATILE PEROXIDASES AND USES THEREOFMay 2024January 2025Allow811NoNo
18661739METHOD FOR PRODUCING SCLAREOL BY FERMENTATION OF CIGAR TOBACCO FLOWER BUDSMay 2024October 2024Allow510NoNo
18662443REGENERATIVE POLYPEPTIDES AND USES THEREOFMay 2024February 2025Allow920YesNo
18660667DNA POLYMERASE MUTANT SUITED TO NUCLEIC ACID AMPLIFICATION FROM RNAMay 2024April 2025Allow1110YesNo
18659585MODIFIED PHI29 DNA POLYMERASES AND USES THEREOFMay 2024November 2024Allow611NoNo
18658938CPF1 PROTEIN AND ITS USE IN GENE EDITINGMay 2024February 2025Allow910NoNo
18650206Improved transfection method using a Sleeping Beauty transposase variant with increased solubility that transfects a target cell when used in protein formApril 2024March 2025Allow1121YesNo
18649712PROCESS FOR PREPARING BETA 3 AGONISTS AND INTERMEDIATESApril 2024October 2024Allow610YesNo
18645049METHODS AND COMPOSITIONS FOR TREATMENT OF HUNTER SYNDROME COMPRISING IDURONATE-2-SULFATASEApril 2024February 2025Allow1010NoNo
18638690BETA-GLYCOSIDASE SS-BGL MUTANT FOR MODIFYING GINSENOSIDE AND APPLICATION THEREOFApril 2024January 2025Allow921NoNo
18635214SERINE PROTEASESApril 2024May 2025Allow1300NoNo
18636074VARIANTS OF TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE AND USES THEREOFApril 2024March 2025Allow1110NoNo
18632080Methods for Producing a Composition Containing Lipids From Recombinant Algae Having High Lipid ProductivityApril 2024May 2025Allow1320NoNo
18631568DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USEApril 2024November 2024Allow700YesNo
18628140ENGINEERED GLUCOSYLTRANSFERASESApril 2024April 2025Allow1211YesNo
18627748METHOD FOR EXTRACTING PULLULAN POLYSACCHARIDE FROM HIGH-VISCOSITY FERMENTATION BROTHApril 2024August 2024Allow510NoNo
18627839DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USEApril 2024August 2024Allow500YesNo
18628461ENGINEERED DNA POLYMERASE VARIANTSApril 2024June 2025Abandon1510NoNo
18623612METHODS AND COMPOSITIONS FOR MODULATING A GENOMEApril 2024April 2025Allow1301YesNo
18623704NUCLEIC ACID MOLECULES ENCODING DNA MODIFYING ENZYMES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND COMPOSITIONS COMPRISING THE SAMEApril 2024August 2024Allow510YesNo
18614099KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANEMarch 2024April 2025Allow1210YesNo
18609707POLYHYDROXYALKANOATE PRODUCTION METHODS AND MATERIALS AND MICROORGANISMS USED IN SAMEMarch 2024April 2025Allow1310NoNo
18606664Enzymatic Methods for Treating Neurodegenerative DisordersMarch 2024November 2024Allow811YesNo
18605166PROCESS FOR THE MANIPULATION OF NUCLEIC ACIDSMarch 2024June 2025Allow1501NoNo
18600576METHOD FOR PRODUCING MULTI-HYDROXY DERIVATIVES OF POLYUNSATURATED FATTY ACIDSMarch 2024January 2025Allow1000NoNo
18596638PROTEOMICS REACTOR, PROTEIN CHROMATOGRAPHIC SEPARATION PLATFORM AND USE THEREOFMarch 2024September 2024Allow610YesNo
18595330PROTEINS TOXIC TO HEMIPTERAN INSECT SPECIESMarch 2024February 2025Allow1101NoNo
18584254BIOFABRICATION OF ADVANCED FUNCTIONAL MATERIALS USING BACTERIAL CELLULOSE SCAFFOLDSFebruary 2024October 2024Allow700NoNo
18581247Method of Manufacturing Sugar Cane Polyvinyl AlcoholFebruary 2024March 2025Allow1311NoNo
18443086GENETICALLY ENCODED SYSTEM FOR CONSTRUCTING AND DETECTING BIOLOGICALLY ACTIVE AGENTSFebruary 2024January 2025Allow1110YesNo
18440901Engineered Reverse Transcriptase Enzymes with Enhanced Enzymatic Activity in Nanoliter Reaction VolumesFebruary 2024January 2025Allow1110NoNo
18439199ALGAL STRAIN AND METHODS FOR PRODUCING SIMPLE SUGARSFebruary 2024December 2024Allow1010NoNo
18437294ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINSFebruary 2024March 2025Allow1311NoNo
18437445GLUCOAMYLASE ENGINEERED YEAST AND FERMENTATION METHODSFebruary 2024April 2025Abandon1410NoNo
18436552FEED COMPOSITION SUPPLEMENTED WITH A PROTEASE COMBINATIONFebruary 2024April 2025Abandon1401NoNo
18435340METHODS FOR MAKING L-GLUFOSINATEFebruary 2024March 2025Allow1410NoNo
18435544METHODS FOR MAKING L-GLUFOSINATEFebruary 2024April 2025Allow1410NoNo
18433433METHOD FOR CYCLIC BIOCHEMICAL CONVERSION OF CARBON DIOXIDE AND HOT GAS COGENERATION IN DEPLETED OIL AND GAS RESERVOIRFebruary 2024February 2025Allow1220NoNo
18434158MUTANT-TYPE RNASE R, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOFFebruary 2024May 2024Allow400YesNo
18433161LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOFFebruary 2024February 2025Allow1321NoNo
18428486STEVIOL GLYCOSIDE TRANSPORTJanuary 2024December 2024Allow1110NoNo
18424815ENGINEERED STABLE NUCLEIC ACID-GUIDED NUCLEASESJanuary 2024September 2024Abandon711NoNo
18424759PFAGO MUTANT PROTEIN WITH MESOPHILIC TARGET NUCLEIC ACID CLEAVAGE ACTIVITY AND APPLICATION THEREOFJanuary 2024June 2024Allow500YesNo
18423707PROCESS FOR DYEING TEXTILES AND ENZYMES USED THEREINJanuary 2024April 2025Allow1411YesNo
18421170PRODUCTION OF FATTY ACYL-COA IN YEAST USING A FATTY ACID FEEDSTOCKJanuary 2024June 2025Allow1720NoNo
18420071Polynucleotides Encoding Engineered Acetate Kinase Variant EnzymesJanuary 2024May 2025Allow1611NoNo
18419647FERMENTATIVE PRODUCTION OF N-BUTYLACRYLATE USING ALCOHOL ACYL TRANSFERASE ENZYMESJanuary 2024March 2025Allow1411NoNo
18418068CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE A COMPOSITIONSJanuary 2024June 2024Allow501NoNo
18415597COMPOSITION OF COMPLEX ENZYME-PROBIOTIC AND ITS APPLICATIONS INTO A METHOD FOR PRODUCING A PREPARATION CONTAINING CHLOROGENIC ACID, PROTOCATECHUIC ACID, AND CAFFEIC ACID HAVING A HIGH CONCENTRATION FROM COFFEE CASCARAJanuary 2024July 2024Allow601NoNo
18414114EVOLUTION OF TALENSJanuary 2024May 2025Abandon1611NoNo
18411153LIQUID FORMULATION OF ALPHA-AMYLASEJanuary 2024May 2025Abandon1701NoNo
18412090INSECT INHIBITORY TOXIN FAMILY ACTIVE AGAINST HEMIPTERAN AND/OR LEPIDOPTERAN INSECTSJanuary 2024March 2025Abandon1411NoNo
18409699TRANSAMINASE POLYPEPTIDESJanuary 2024June 2025Allow1811YesNo
18405043Host Cell Including Expression Vector for Encoding Catalysis Deactivated Angiotensin- Converting Enzyme 2 (ACE2) VariantsJanuary 2024June 2025Allow1721NoNo
18406057BIOSENSORS FOR DETECTING AND/OR NEUTRALIZING BIOAVAILABLE URANIUM AND RELATED U-SENSITIVE GENETIC MOLECULAR COMPONENTS, GENE CASSETTES, VECTORS, GENETIC CIRCUITS, COMPOSITIONS, METHODS AND SYSTEMSJanuary 2024June 2025Allow1811NoNo
18404047CHITIN AND PROCESS FOR PRODUCING CHITIN AND/OR CHITOSAN BY THE ENZYMATIC AND CHEMICAL PATHWAYJanuary 2024February 2025Allow1310YesNo
18403265ENGINEERED URIDINE PHOSPHORYLASE VARIANT ENZYMESJanuary 2024June 2025Allow1711NoNo
18402680ENGINEERED NUCLEIC ACID-GUIDED NUCLEASESJanuary 2024July 2024Allow610YesNo
18395001Hyaluronidase Enzyme Formulations for High Volume AdministrationDecember 2023October 2024Allow1031YesNo
18393317METHANE MONOOXYGENASE ENZYMESDecember 2023March 2025Allow1511NoNo
18393303CASZ COMPOSITIONS AND METHODS OF USEDecember 2023December 2024Abandon1211NoNo
18389919ANTICOAGULANT FUSION PROTEINS AND USES THEREOFDecember 2023January 2025Abandon1301NoNo
18389738SYSTEMS AND METHODS FOR GENETIC ENGINEERING OF A POLYPLOID ORGANISMDecember 2023March 2025Allow1511NoNo
18545514OPTIMIZATION OF YEAST HOST CELLS FOR THE PRODUCTION OF HETEROLOGOUS PROTEINSDecember 2023January 2025Allow1300YesNo
18569989ENZYMATIC METHOD FOR THE PRODUCTION OF L-GLUFOSINATE P-ALKYL ESTERSDecember 2023June 2025Allow1831YesNo
18532727AUTOMATED BIOCONVERSION PROCESS FOR CONTINUOUS AND AUTOMATIC CONTROL FOR CO BIOCONVERSIONSDecember 2023January 2025Allow1320NoNo
18529216METHODS FOR PRODUCING MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICSDecember 2023February 2025Allow1420NoNo
18528794METHOD OF ETHANOL FERMENTATION WITH CELLULOSE AT HIGH-SOLIDS LOADINGDecember 2023April 2025Allow1640YesNo
18524651RECOMBINANT BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH METHIONINE METABOLISM AND METHODS OF USE THEREOFNovember 2023August 2024Abandon901NoNo
18525234UDP-DEPENDENT GLYCOSYLTRANSFERASE FOR HIGH EFFICIENCY PRODUCTION OF REBAUDIOSIDESNovember 2023April 2025Allow1610NoNo
18524834METHODS AND COMPOSITIONS FOR EFFICIENT GENETIC MODIFICATIONS OF BACILLUS LICHENIFORMIS STRAINSNovember 2023December 2024Allow1300NoNo
18522203METHOD FOR PREPARING (S)-NICOTINE BY REDUCTIONNovember 2023February 2025Allow1410NoNo
18521466POLYMERASE COMPOSITIONS AND KITS, AND METHODS OF USING AND MAKING THE SAMENovember 2023April 2025Allow1711YesNo
18516805YEAST EXPRESSING A HETEROLOGOUS TREHALASE FOR ETHANOL PRODUCTIONNovember 2023May 2025Allow1821NoNo
18515787Compositions for Facilitating the Removal of a FingerprintNovember 2023October 2024Allow1110NoNo
18511394METHODS OF PRODUCING MORPHINAN ALKALOIDS AND DERIVATIVESNovember 2023June 2025Allow1910NoNo
18561258ENHANCING FORMATION OF HUMAN MILK OLIGOSACCHARIDES (HMOS) BY MODIFYING LACTOSE IMPORT IN THE CELLNovember 2023December 2024Allow1311YesNo
18508594PROCESS FOR PREPARING BETA 3 AGONISTS AND INTERMEDIATESNovember 2023February 2025Abandon1510NoNo
18506648Liquid Cleaning Compositions Comprising Protease VariantsNovember 2023December 2024Allow1410NoNo
18504743Liquid Cleaning Compositions Comprising Protease VariantsNovember 2023December 2024Allow1320YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1652.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
151
Examiner Affirmed
93
(61.6%)
Examiner Reversed
58
(38.4%)
Reversal Percentile
76.4%
Higher than average

What This Means

With a 38.4% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
1322
Allowed After Appeal Filing
362
(27.4%)
Not Allowed After Appeal Filing
960
(72.6%)
Filing Benefit Percentile
22.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 27.4% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

✓ Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

⚠ Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Art Unit 1652 - Prosecution Statistics Summary

Executive Summary

Art Unit 1652 is part of Group 1650 in Technology Center 1600. This art unit has examined 16,692 patent applications in our dataset, with an overall allowance rate of 65.4%. Applications typically reach final disposition in approximately 29 months.

Comparative Analysis

Art Unit 1652's allowance rate of 65.4% places it in the 21% percentile among all USPTO art units. This art unit has a significantly lower allowance rate than most art units at the USPTO.

Prosecution Patterns

Applications in Art Unit 1652 receive an average of 1.68 office actions before reaching final disposition (in the 37% percentile). The median prosecution time is 29 months (in the 47% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more challenging examination environment compared to the USPTO average.
  • With fewer office actions than average, plan for relatively streamlined prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.