USPTO Examiner EPSTEIN TODD MATTHEW - Art Unit 1652

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19186618GERMACRENE SYNTHASE SgTPS7 PROTEIN, CODING GENE AND USE IN SYNTHESIS OF GERMACRENEApril 2025November 2025Allow710YesNo
18933327CARBONYL REDUCTASE MUTANT AND ITS APPLICATIONOctober 2024March 2025Allow510NoNo
18859487ALDITOL OXIDASE AND APPLICATION THEREOFOctober 2024February 2025Allow400NoNo
18846061ENZYMATIC METHOD FOR THE PRODUCTION OF L-GLUFOSINATE P-ESTERSSeptember 2024June 2025Allow910YesNo
18825195GENETIC ENGINEERING BACTERIUM FOR DE NOVO SYNTHESIS OF CIS,CIS-MUCONIC ACID BY TAKING GLUCOSE AS SUBSTRATE AND APPLICATIONS THEREOFSeptember 2024April 2025Allow820YesNo
18658938CPF1 PROTEIN AND ITS USE IN GENE EDITINGMay 2024February 2025Allow910NoNo
18595947Methods Of Producing Omega-Hydroxylated Fatty Acid DerivativesMarch 2024December 2025Allow2120NoNo
18420028ESCHERICHIA COLI FOR SYNTHESIZING L-VALINE, CONSTRUCTION METHOD AND USE THEREOFJanuary 2024July 2025Allow1810YesNo
18413338ENGINEERED ADENYLATE KINASE VARIANT ENZYMESJanuary 2024February 2026Abandon2511NoNo
18393317METHANE MONOOXYGENASE ENZYMESDecember 2023March 2025Allow1511NoNo
18390570MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESISDecember 2023September 2025Allow2121NoNo
18544037PROCESS FOR ETHANOL PRODUCTIONDecember 2023March 2026Abandon2720NoNo
18542109GLUTAMATE DECARBOXYLASE MUTANT WITH IMPROVED PH TOLERANCE AND USE THEREOF IN SYNTHESIS OF GAMMA-AMINOBUTYRIC ACIDDecember 2023August 2025Allow2010NoNo
18533016ENGINEERED BETA-SUBUNIT OF TRYPTOPHAN SYNTHASE FOR PRODUCTION OF NON-CANONICAL AMINO ACIDSDecember 2023September 2025Allow2121YesNo
18503526BETA-GALACTOSIDASE ENZYMESNovember 2023April 2025Allow1710YesNo
18351633TREATMENT OF RETINITIS PIGMENTOSA USING ENGINEERED MEGANUCLEASESJuly 2023April 2025Abandon2110NoNo
18344219PRODUCTION OF FATTY ACID DERIVATIVESJune 2023February 2026Allow3221YesNo
18329971Animal Feed Additives Comprising a Polypeptide having Protease Activity and Uses ThereofJune 2023February 2026Allow3241YesNo
18330340PROCESSES FOR PRODUCTION OF ALKYLATED FATTY ACIDS AND DERIVATIVES THEREOFJune 2023July 2025Abandon2511NoNo
17640807RECOMBINANT ESCHERICHIA COLI FOR PRODUCING GLUTARATE, CONSTRUCTION METHOD AND USE THEREOFJune 2023July 2025Allow4010YesNo
18327386GH30 in Wet MillingJune 2023November 2025Allow2910NoNo
18325714CHIMERIC ALKALINE PHOSPHATASE-LIKE PROTEINSMay 2023September 2025Allow2811NoNo
18319444RECOMBINANT BACTERIAL CELLS AND METHODS FOR PRODUCING POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYVALERATE)May 2023November 2023Allow601NoNo
18319442RECOMBINANT BACTERIAL CELLS AND METHODS FOR PRODUCING POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYVALERATE)May 2023March 2024Allow1011NoNo
18034449Method for the Production of Thiocarbamate Derivatives A2AR InhibitorsApril 2023March 2026Abandon3501NoNo
18302911METHOD OF PRODUCING CALCIUM PROPIONATE BY USING LACTOBACILLUS REUTERIApril 2023November 2023Allow710NoNo
18031545Engineered microorganisms expressing acetoacetyl-CoA reductase variants and method for improving the yield of PHAApril 2023October 2023Allow710YesNo
18132027Recombinant Production of Steviol GlycosidesApril 2023May 2025Allow2510YesNo
18188043PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITORMarch 2023December 2024Abandon2110NoNo
18121226High Purity Protein Preparation from Plant Material and Products ThereofMarch 2023December 2025Abandon3450NoNo
18043258FLAVIN-DEPENDENT OXIDASES HAVING CANNABINOID SYNTHASE ACTIVITYFebruary 2023December 2025Abandon3401NoNo
18172594MICROBIAL PRODUCTION OF ROTUNDONEFebruary 2023September 2024Allow1911NoNo
18166707PROTEASE VARIANTS AND USES THEREOFFebruary 2023February 2026Abandon3620NoNo
18164522BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMSFebruary 2023August 2024Allow1811NoNo
18006310ENZYMES AND METHODS FOR PRODUCTION OF MALONIC ACID AND DERIVATIVES THEREOFJanuary 2023February 2026Abandon3601NoNo
18006316ENZYMES AND METHODS FOR PRODUCTION OF MALONIC ACID AND DERIVATIVES THEREOFJanuary 2023March 2026Abandon3810NoNo
18005079USE OF UV-ACTIVATED ENZYMES TO IMPLEMENT OXIDATION REACTIONS AND THE CORRESPONDING PROCESSESJanuary 2023February 2026Abandon3701NoNo
18004364METHOD FOR THE FERMENTATIVE PRODUCTION OF GUANIDINOACETIC ACIDJanuary 2023February 2024Allow1321YesNo
18149872YEAST PROMOTORS FOR PROTEIN EXPRESSIONJanuary 2023November 2024Allow2321NoNo
18146661METHODS AND COMPOSITIONS INVOLVING PROMOTERS DERIVED FROM YARROWIA LIPOLYTICADecember 2022February 2025Abandon2620NoNo
18145073ESTERASES AND USES THEREOFDecember 2022November 2023Allow1010NoNo
17927023PHYTASE MUTANTNovember 2022February 2026Allow3921NoNo
18056728DEHYDROGENASE MUTANT L283V/L286V, AND PREPARATION METHOD AND USE THEREOFNovember 2022September 2023Allow1010YesNo
17926487CELLS AND METHODS FOR PRODUCING METHYL KETONESNovember 2022January 2026Allow3820NoNo
17998217METHOD FOR PREPARING PYRROLIDONENovember 2022October 2024Abandon2320NoNo
17961625BETA-GALACTOSIDASE ENZYMESOctober 2022August 2023Allow1110NoNo
17917549ENGINEERED BIOSYNTHETIC PATHWAYS FOR PRODUCTION OF ECTOINE BY FERMENTATIONOctober 2022December 2025Abandon3910NoNo
17910787METHOD FOR PREPARING L-GLUFOSINATE AMMONIUM BY BIOLOGICAL ENZYMATIC DE-RACEMIZATION, GLUFOSINATE AMMONIUM DEHYDROGENASE MUTANT AND USE THEREOFSeptember 2022September 2025Allow3620NoNo
17823853COFACTOR SELF-SUFFICIENT ESCHERICHIA COLI AND CONSTRUCTION METHOD AND APPLICATION THEREOFAugust 2022June 2024Allow2210YesNo
17823471MICROBIAL FERMENTATION FOR THE PRODUCTION OF TERPENESAugust 2022January 2025Allow2930NoNo
17908059GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYHEXANEDIOIC ACID AND/OR (E)-HEX-2-ENEDIOIC ACID AND PRODUCTION METHOD FOR SAID CHEMICALSAugust 2022January 2026Allow4010NoNo
17823034OLEIC ACID PRODUCED FROM MICROORGANISM AND METHOD FOR PRODUCING OLEIC ACID USING MICROORGANISMAugust 2022May 2025Abandon3340NoNo
17821404MICROBIAL FERMENTATION FOR THE PRODUCTION OF ISOPRENOID ALCOHOLS AND DERIVATIVESAugust 2022September 2024Abandon3211NoNo
17800898METHODS AND SYSTEMS FOR LACTIC ACID PRODUCTION AND POLYLACTIC ACID RECYCLINGAugust 2022February 2026Allow4211NoNo
17819065NPP1 FUSION PROTEINSAugust 2022May 2025Abandon3421NoNo
17883115BACTERIAL N-DEMTHYLASES AS BIOCATALYSTS FOR THE PRODUCTION OF METHYLXANTHINESAugust 2022July 2025Allow3641NoNo
17816586METHOD FOR PRODUCING VANILLINAugust 2022November 2024Allow2830YesNo
17878040ALKALINE PROTEASE MUTANT, AND GENE, ENGINEERED STRAIN, PREPARATION METHOD AND APPLICATION THEREOFJuly 2022January 2023Allow500YesNo
17858801Variants of Family a Dna Polymerase and Uses ThereofJuly 2022November 2024Allow2831YesNo
17790787Use of Biological Enzyme for Preparing Orlistat Intermediate, and Preparation MethodJuly 2022August 2025Allow3710NoNo
17838078DNA POLYMERASESJune 2022August 2024Abandon2720NoNo
17784304GENETICALLY ENGINEERED MICROORGANISM CAPABLE OF GROWING ON FORMATE, METHANOL, METHANE OR CO2June 2022December 2025Allow4210YesNo
17836566METHOD FOR INCREASING THE PRODUCTION OF SMALL MOLECULES IN SUBMERGED CORYNEBACTERIUM CULTUREJune 2022April 2025Allow3420NoNo
17806138BIOLOGICAL DEVICES AND METHODS OF USE THEREOF TO PRODUCE STEVIOL GLYCOSIDESJune 2022March 2026Allow4531NoNo
17830420Method for Producing D-psicoseJune 2022July 2023Allow1410YesNo
17780423METHOD FOR PRODUCING HETEROGENOUS CANNABICHROMENE FROM SACCHAROMYCES CEREVISIAEMay 2022December 2025Abandon4211NoNo
17751277Compositions and Methods for Producing High Secreted Yields of Recombinant ProteinsMay 2022June 2024Allow2511NoNo
17750293METHOD FOR THE IN VIVO SYNTHESIS OF 4-HYDROXYMETHYLFURFURAL AND DERIVATIVES THEREOFMay 2022September 2024Allow2811YesNo
17744300SYSTEM FOR IMPROVED PRODUCTION TITERS IN FERMENTATIONSMay 2022March 2024Allow2211NoNo
17740550METHOD OF PRODUCING VALUE-ADDED CHEMICALS BY USING CLOSTRIDIUM AND BACILLUS CO-CULTURESMay 2022April 2024Allow2421NoNo
17775649MONOMER POLYPEPTIDE HAVING HYDROGENASE ACTIVITY, IN PARTICULAR RECOMBINANT MONOMER POLYPEPTIDE HAVING HYDROGENASE ACTIVITYMay 2022January 2026Allow4520YesNo
17755266TRANSAMINASE MUTANT AND USE THEREOFApril 2022August 2025Allow4011NoNo
17717141Compositions and methods for converting methanol into hydrogen peroxide and carbon dioxideApril 2022August 2025Abandon4010NoNo
17658214SYNTHESIS OF BETA-HYDROXYISOVALERATE AND METHODS OF USEApril 2022October 2024Allow3021YesNo
17711382ENGINEERED ADENYLATE KINASE VARIANT ENZYMESApril 2022October 2023Allow1811NoNo
17765645DNA POLYMERASE AND DNA POLYMERASE DERIVED 3'-5'EXONUCLEASEMarch 2022December 2025Allow4421YesNo
17693349RECOMBINANT STRAIN FOR PRODUCING SHIKIMIC ACID, AND CONSTRUCTION METHOD AND USE THEREOFMarch 2022July 2025Allow4020YesNo
17691010MICROORGANISMS FOR THE PRODUCTION OF ADIPIC ACID AND OTHER COMPOUNDSMarch 2022December 2023Abandon2110NoNo
17641358TRANSFORMED MICROORGANISM AND METHOD OF PRODUCING POLYHYDROXYALKANOATE USING THE MICROORGANISMMarch 2022March 2025Allow3610NoNo
17652835METHODS OF PRODUCING SUCCINIC ACID FROM A BIOMASSFebruary 2022December 2023Allow2120NoNo
17679855BACTERIAL ENGINEERINGFebruary 2022July 2023Abandon1601NoNo
17674712COMPOSITIONS COMPRISING POLYPEPTIDES HAVING XYLANASE ACTIVITY AND POLYPEPTIDES HAVING ARABINOFURANOSIDASE ACTIVITYFebruary 2022June 2023Allow1610YesNo
17665441BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORSFebruary 2022June 2025Abandon4101NoNo
17585527TREATMENT OF RETINITIS PIGMENTOSA USING ENGINEERED MEGANUCLEASESJanuary 2022October 2023Abandon2111NoNo
17629485METHOD FOR PREPARING BLOCK COPOLYMERJanuary 2022June 2025Allow4020NoNo
17625783ESTERASES AND USES THEREOFJanuary 2022February 2025Allow3711NoNo
17619431SELECTIVE PROCESS FOR PREPARING SULFOXIDES BY ENZYMATIC CATALYSISDecember 2021February 2026Abandon5030NoNo
17545616METHOD FOR THE IN VIVO SYNTHESIS OF 4-HYDROXYMETHYLFURFURAL AND DERIVATIVES THEREOFDecember 2021January 2024Allow2620NoNo
17544026Detergent CompositionDecember 2021March 2024Allow2720YesNo
17533739MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETONovember 2021February 2023Allow1520YesNo
17505945MACHINE LEARNING GENE MINING METHOD AND PHOSPHINOTHRICIN DEHYDROGENASE MUTANT FOR AMINO TRANSLOCATIONOctober 2021May 2023Allow1911YesNo
17603259STABILIZED GLYCOSIDE HYDROLASE VARIANTSOctober 2021January 2026Allow5121NoNo
17471615Recombinant Production of Steviol GlycosidesSeptember 2021June 2023Abandon2110NoNo
17461102METHANE MONOOXYGENASE ENZYMESAugust 2021August 2023Allow2311YesNo
17426569SUBTILASE VARIANTS AND COMPOSITIONS COMPRISING SAMEJuly 2021December 2025Allow5221NoNo
17387806PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITORJuly 2021April 2023Abandon2110NoNo
17375462ENGINEERED CAS9 NUCLEASESJuly 2021October 2024Allow3921NoNo
17354819ALPHA (1,2) FUCOSYLTRANSFERASE SYNGENES FOR USE IN THE PRODUCTION OF FUCOSYLATED OLIGOSACCHARIDESJune 2021December 2022Allow1800NoNo
17335812Production Of Fatty Acid DerivativesJune 2021October 2023Abandon2811NoNo
17333141RECOMBINANT MUTANT MICROORGANISM AND METHOD FOR PRODUCING CADAVERINE BY USING SAME MICROORGANISMMay 2021October 2024Abandon4140YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner EPSTEIN, TODD MATTHEW.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
5
Examiner Affirmed
3
(60.0%)
Examiner Reversed
2
(40.0%)
Reversal Percentile
60.9%
Higher than average

What This Means

With a 40.0% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
21
Allowed After Appeal Filing
5
(23.8%)
Not Allowed After Appeal Filing
16
(76.2%)
Filing Benefit Percentile
32.4%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 23.8% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner EPSTEIN, TODD MATTHEW - Prosecution Strategy Guide

Executive Summary

Examiner EPSTEIN, TODD MATTHEW works in Art Unit 1652 and has examined 507 patent applications in our dataset. With an allowance rate of 57.6%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 29 months.

Allowance Patterns

Examiner EPSTEIN, TODD MATTHEW's allowance rate of 57.6% places them in the 18% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by EPSTEIN, TODD MATTHEW receive 2.12 office actions before reaching final disposition. This places the examiner in the 57% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by EPSTEIN, TODD MATTHEW is 29 months. This places the examiner in the 62% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +54.2% benefit to allowance rate for applications examined by EPSTEIN, TODD MATTHEW. This interview benefit is in the 95% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 23.6% of applications are subsequently allowed. This success rate is in the 33% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 43.1% of cases where such amendments are filed. This entry rate is in the 66% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 50.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 42% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 61.5% of appeals filed. This is in the 39% percentile among all examiners. Of these withdrawals, 75.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 88.6% are granted (fully or in part). This grant rate is in the 88% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.7% of allowed cases (in the 57% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.