USPTO Art Unit 1684 Prosecution Statistics

Art Unit Information

Art Unit: 1684
Group: 1680
Tech Center: 1600
Total Cases: 547
Last Active: October 2025

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19361770COMPOSITIONS AND METHODS FOR MOLECULAR LABELINGOctober 2025March 2026Allow510NoNo
19283119SYSTEMS AND METHODS FOR TRANSFER OF REAGENTS BETWEEN DROPLETSJuly 2025March 2026Allow711YesNo
19251197METHODS AND SYSTEMS FOR GENETIC ANALYSISJune 2025January 2026Allow711NoNo
19202222METHODS FOR PREPARING 5'-END LIGATION-BASED ssDNA-SPECIFIC SEQUENCING LIBRARIESMay 2025December 2025Allow720NoNo
19188895DIRECT-TO-LIBRARY METHODS, SYSTEMS, AND COMPOSITIONSApril 2025February 2026Allow1010NoNo
19180024SYSTEMS AND METHODS FOR BIOMOLECULE RETENTIONApril 2025October 2025Allow711NoNo
19079081METHODS AND KITS FOR LABELING CELLULAR MOLECULESMarch 2025September 2025Allow710YesNo
19069064ANALYSIS OF NUCLEIC ACID SEQUENCESMarch 2025March 2026Abandon1220YesNo
19060201SINGLE-STRANDED END PRESERVING ADAPTORSFebruary 2025March 2026Allow1321YesNo
19056112METHODS AND SYSTEMS FOR GENETIC ANALYSISFebruary 2025November 2025Allow911NoNo
19044599COMPOSITIONS AND METHODS FOR EVALUATING GENOMIC ALTERATIONSFebruary 2025August 2025Allow611YesNo
19028468PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTSJanuary 2025November 2025Allow1020YesNo
19027603METHODS AND KITS FOR LABELING CELLULAR MOLECULESJanuary 2025June 2025Allow511NoNo
19027486METHODS AND KITS FOR LABELING CELLULAR MOLECULESJanuary 2025August 2025Allow710NoNo
19027542METHODS AND KITS FOR LABELING CELLULAR MOLECULESJanuary 2025June 2025Allow511NoNo
19016998METHODS AND SYSTEMS FOR DROPLET-BASED SINGLE CELL BARCODINGJanuary 2025November 2025Abandon1001NoNo
18972564USE OF DNA ORIGAMI NANOSTRUCTURES FOR MOLECULAR INFORMATION BASED DATA STORAGE SYSTEMSDecember 2024June 2025Allow611NoNo
18960791ASSAYS AND OTHER REACTIONS INVOLVING DROPLETSNovember 2024March 2025Allow410NoNo
18951533ANALYSIS OF NUCLEIC ACID SEQUENCESNovember 2024April 2025Allow520YesNo
18945323METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDESNovember 2024August 2025Abandon901NoNo
18929514ANALYSIS OF NUCLEIC ACID SEQUENCESOctober 2024February 2025Allow410YesNo
18918205METHODS AND KITS FOR LABELING CELLULAR MOLECULESOctober 2024January 2025Allow310NoNo
18906096MULTIPLEX LABELING OF MOLECULES BY SEQUENTIAL HYBRIDIZATION BARCODINGOctober 2024April 2025Allow610NoNo
18892893METHODS OF OPTIMIZING GENE EXPRESSION IN PLANTSeptember 2024July 2025Allow911NoNo
18893597METHODS FOR TREATMENT OF THYROID CANCERSeptember 2024April 2025Allow711NoNo
18887088METHODS AND KITS FOR LABELING CELLULAR MOLECULESSeptember 2024April 2025Allow711NoNo
18887084METHODS AND KITS FOR LABELING CELLULAR MOLECULESSeptember 2024April 2025Allow711NoNo
18887080METHODS AND KITS FOR LABELING CELLULAR MOLECULESSeptember 2024March 2025Allow611NoNo
18827961LINKED TARGET CAPTURESeptember 2024May 2025Allow811NoNo
18827964LINKED TARGET CAPTURESeptember 2024May 2025Allow811YesNo
18824319METHODS AND SYSTEMS FOR GENETIC ANALYSISSeptember 2024March 2025Allow711NoNo
18823253METHODS FOR CLASSIFICATION OF TISSUE SAMPLES AS POSITIVE OR NEGATIVE FOR CANCERSeptember 2024February 2025Allow611YesNo
18810294PROBE-BASED ANALYSIS OF NUCLEIC ACIDS AND PROTEINSAugust 2024June 2025Abandon1010YesNo
18807409SINGLE DOMAIN ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICSAugust 2024February 2025Allow601YesNo
18800910MACROMOLECULE ANALYSIS EMPLOYING NUCLEIC ACID ENCODINGAugust 2024December 2024Allow410NoNo
18799749METHODS AND KITS USING NUCLEIC ACID ENCODING AND/OR LABELAugust 2024July 2025Allow1120NoNo
18791671METHODS OF SEQUENCING LINKED FRAGMENTSAugust 2024March 2025Allow811NoNo
18791664METHODS OF SEQUENCING LINKED FRAGMENTSAugust 2024January 2025Allow610NoNo
18791675LINKED TARGET CAPTUREAugust 2024January 2025Allow610NoNo
18791679LINKED TARGET CAPTUREAugust 2024March 2025Allow811YesNo
18787946KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABELJuly 2024March 2025Allow820NoNo
18786391ANALYSIS OF NUCLEIC ACID SEQUENCESJuly 2024March 2025Allow711YesNo
18784019METHODS AND KITS FOR LABELING CELLULAR MOLECULESJuly 2024January 2025Allow611NoNo
18770462SYSTEMS AND METHODS FOR BIOMOLECULE RETENTIONJuly 2024January 2025Allow711YesNo
18764943N-TERMINAL MODIFIER AGENTS AND BINDERS FOR TREATING AND ANALYZING PEPTIDESJuly 2024July 2025Allow1221YesNo
18764600EFFICIENTLY CHARACTERIZING PROTEIN-PROTEIN INTERACTIONSJuly 2024October 2024Allow300YesNo
18753319METHODS AND KITS FOR LABELING CELLULAR MOLECULESJune 2024January 2025Allow711NoNo
18734832Perturbation Beads for Use in AssaysJune 2024October 2025Allow1721YesNo
18678577DETECTING MUTATIONS AND PLOIDY IN CHROMOSOMAL SEGMENTSMay 2024October 2024Allow510NoNo
18672510MULTIPLEXED SEQUENCING IN CELLS AND TISSUESMay 2024January 2026Allow2031NoNo
18660053MACROMOLECULE ANALYSIS EMPLOYING NUCLEIC ACID ENCODINGMay 2024June 2025Allow1400NoNo
18659334MACROMOLECULE ANALYSIS EMPLOYING NUCLEIC ACID ENCODINGMay 2024March 2025Allow1000NoNo
18653506SANDWICH ASSAYS IN DROPLETSMay 2024November 2024Allow610YesNo
18650305METHODS AND KITS FOR LABELING CELLULAR MOLECULESApril 2024October 2024Allow510NoNo
18644702SYSTEMS, METHODS, AND COMPOSITIONS FOR PRODUCTION OF CELLULAR AGRICULTURE PRODUCTSApril 2024January 2026Abandon2141YesNo
18643692METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDESApril 2024September 2024Allow511NoNo
18643523TISSUE SPATIAL OMICSApril 2024September 2025Allow1721NoNo
18636923METHODS FOR DIAGNOSING AND ASSESSING DISEASE USING DRAIN FLUIDApril 2024October 2024Allow620NoNo
18622603HIGH PERFORMANCE SPATIAL MAPPING OF INDIVIDUAL TARGETS USING RELEASABLE HANDSHAKE SEQUENCESMarch 2024March 2026Allow2331YesNo
18610717METHODS AND COMPOSITIONS USING ONE-SIDED TRANSPOSITIONMarch 2024March 2025Allow1210NoNo
18592885DNA ARRAYMarch 2024February 2025Allow1110YesNo
18592843DNA CONCATEMERS ON A SURFACEMarch 2024February 2025Allow1110YesNo
18593788METHODS AND SYSTEMS FOR ANALYSISMarch 2024December 2024Allow911NoNo
18593406METHODS AND SYSTEMS FOR GENETIC ANALYSISMarch 2024November 2024Allow811NoNo
18592484ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICSFebruary 2024March 2025Allow1200YesNo
18592499ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICSFebruary 2024February 2025Allow1200YesNo
18592473ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICSFebruary 2024February 2025Allow1211YesNo
18592456ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICSFebruary 2024February 2025Allow1211YesNo
18590738ARRAYS INCLUDING A RESIN FILM AND A PATTERNED POLYMER LAYERFebruary 2024April 2025Allow1410NoNo
18439353METHODS AND COMPOSITIONS FOR CELL-FREE CLONINGFebruary 2024April 2025Allow1420NoNo
18433344METHOD FOR PREDICTING THE OFF-TARGET BINDING OF A PEPTIDE WHICH BINDS TO A TARGET PEPTIDE PRESENTED BY A MAJOR HISTOCOMPATIBILITY COMPLEXFebruary 2024March 2026Abandon2520NoNo
18431569ATAC-ARRAY FOR PREDICTION OF DISEASE-FREE SURVIVAL IN PANCREATIC CANCERFebruary 2024October 2025Allow2122NoNo
18409174METHODS, COMPOSITIONS, AND SYSTEMS FOR SPATIAL ANALYSIS OF ANALYTES IN A BIOLOGICAL SAMPLEJanuary 2024May 2025Allow1610YesNo
18402273METHODS OF SELECTING BINDING REAGENTSJanuary 2024January 2026Allow2540YesNo
18402501HIGHLY SENSITIVE IN VITRO ASSAYS TO DEFINE SUBSTRATE PREFERENCES AND SITES OF NUCLEIC-ACID BINDING, MODIFYING, AND CLEAVING AGENTSJanuary 2024December 2025Allow2410NoNo
18397801PLANTS AND SEEDS OF HYBRID CORN VARIETY CH010574December 2023January 2026Allow2510NoNo
18394765PLANTS AND SEEDS OF CORN VARIETY CV638143December 2023December 2025Allow2410NoNo
18394527PLANTS AND SEEDS OF HYBRID CORN VARIETY CH010451December 2023December 2025Allow2410NoNo
18542058NUCLEIC ACID INDEXING TECHNIQUESDecember 2023February 2026Allow2611YesNo
18536721METHODS AND KITS FOR LABELING CELLULAR MOLECULESDecember 2023December 2024Allow1211NoNo
18536766METHODS AND KITS FOR LABELING CELLULAR MOLECULESDecember 2023November 2024Allow1111YesNo
18535886PLANTS AND SEEDS OF HYBRID CORN VARIETY CH010461December 2023December 2025Allow2410NoNo
18534150DNA-BARCODED ANTIGEN MULTIMERS AND METHOD OF USE THEREOFDecember 2023October 2024Abandon1001NoNo
18520514METHODS AND COMPOSITIONS FOR NUCLEIC ACID ANALYSISNovember 2023June 2025Allow1810NoNo
18510295ENRICHMENT OF SHORT NUCLEIC ACID FRAGMENTS IN SEQUENCING LIBRARY PREPARATIONNovember 2023April 2025Allow1700NoNo
18506751METHOD AND KIT FOR THE GENERATION OF DNA LIBRARIES FOR MASSIVELY PARALLEL SEQUENCINGNovember 2023December 2025Allow2501NoNo
18388735PROCESSES AND SYSTEMS FOR PREPARATION OF NUCLEIC ACID SEQUENCING LIBRARIES AND LIBRARIES PREPARED USING SAMENovember 2023October 2025Allow2320YesNo
18502817HIGHLY SENSITIVE IN VITRO ASSAYS TO DEFINE SUBSTRATE PREFERENCES AND SITES OF NUCLEIC-ACID BINDING, MODIFYING, AND CLEAVING AGENTSNovember 2023December 2025Allow2610NoNo
18559031DEUTERATED INDOLE HEPTAMETHINE CYANINE DYESNovember 2023June 2025Allow2021YesNo
18499332MACROCYCLIC MODULATORS OF DISEASE ASSOCIATED PROTEIN MISFOLDING AND AGGREGATIONNovember 2023October 2025Allow2411NoNo
18493211METHODS AND COMPOSITIONS FOR IDENTIFYING EPITOPESOctober 2023May 2025Allow1910NoNo
18492620METHODS, COMPOSITIONS, AND SYSTEMS FOR MAPPING LOCATIONS OF SINGLE MOLECULES IN MULTI-DIMENSIONAL SPACEOctober 2023November 2025Allow2551YesNo
18492069MAMMALIAN CELLS AND METHODS FOR ENGINEERING THE SAMEOctober 2023November 2024Allow1312YesNo
18489381METHODS OF SEQUENCING WITH LINKED FRAGMENTSOctober 2023November 2025Allow2520YesNo
18484871HIGH THROUGHPUT PROTEIN-PROTEIN INTERACTION SCREENING IN YEAST LIQUID CULTUREOctober 2023November 2025Abandon2620NoNo
18482755PEPTIDE DEFICIENT-MHC CLASS I/CHAPERONE COMPOSITIONS AND METHODSOctober 2023January 2026Allow2720YesNo
18481497BINDING POLYPEPTIDES AND METHODS OF MAKING THE SAMEOctober 2023October 2025Abandon2501NoNo
18466208CAPACITOR WITH MULTIPLE ELEMENTS FOR MULTIPLE REPLACEMENT APPLICATIONSSeptember 2023September 2024Allow1210NoNo
18465687DOUBLE-STRANDED SPLINT ADAPTORS WITH UNIVERSAL LONG SPLINT STRANDS AND METHODS OF USESeptember 2023March 2025Allow1821NoNo
18462747ENGINEERED ENVELOPED VECTORS AND METHODS OF USE THEREOFSeptember 2023March 2025Allow1921NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1684.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
4
Examiner Affirmed
1
(25.0%)
Examiner Reversed
3
(75.0%)
Reversal Percentile
97.8%
Higher than average

What This Means

With a 75.0% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
39
Allowed After Appeal Filing
10
(25.6%)
Not Allowed After Appeal Filing
29
(74.4%)
Filing Benefit Percentile
17.7%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 25.6% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

✓ Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

⚠ Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Art Unit 1684 - Prosecution Statistics Summary

Executive Summary

Art Unit 1684 is part of Group 1680 in Technology Center 1600. This art unit has examined 547 patent applications in our dataset, with an overall allowance rate of 69.3%. Applications typically reach final disposition in approximately 51 months.

Comparative Analysis

Art Unit 1684's allowance rate of 69.3% places it in the 30% percentile among all USPTO art units. This art unit has a below-average allowance rate compared to other art units.

Prosecution Patterns

Applications in Art Unit 1684 receive an average of 2.35 office actions before reaching final disposition (in the 80% percentile). The median prosecution time is 51 months (in the 1% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more challenging examination environment compared to the USPTO average.
  • With more office actions than average, plan for multiple rounds of prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.