USPTO Art Unit 1651 Prosecution Statistics

Art Unit Information

Art Unit: 1651
Group: 1650
Tech Center: 1600
Total Cases: 14,593
Last Active: August 2025

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19309246BACTERIOPHAGE COMPOSITIONS FOR TREATING STAPHYLOCOCCUS INFECTIONAugust 2025March 2026Allow701YesNo
19228731ENTERAL SUSTAINED-RELEASE SUGAR ALCOHOL ADDITIVE AND PREPARATION METHOD AND APPLICATION THEREOFJune 2025November 2025Allow510NoNo
19207422ASPERGILLUS FUMIGATUS FOR DEGRADING SOIL MICROPLASTICS AND APPLICATION THEREOFMay 2025December 2025Allow720NoNo
19089650ELECTROPORATION-TARGETED DELIVERY OF RIBOSOME INACTIVATING PROTEIN GELONIN INTO MAMMALIAN CELLSMarch 2025October 2025Allow610NoNo
19028618SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSJanuary 2025July 2025Allow610YesNo
19023930GRAIN FRACTIONATION PROCESSJanuary 2025October 2025Allow911YesNo
19005540PREPARATION AND APPLICATION OF HIGH-ACTIVITY AND HIGH-SAFETY CARDAMINE VIOLIFOLIA SELENOPROTEIN STANDARD SAMPLEDecember 2024June 2025Allow510NoNo
18964948Compositions and Methods for Cleaning Contaminated Solids and LiquidsDecember 2024January 2026Abandon1310NoNo
18935623PROCESS FOR PRODUCTION OF A SOLUBLE AND INSOLUBLE COLLAGEN PRODUCT FROM MAMMALIAN DERMIS TISSUENovember 2024May 2025Allow611YesNo
18935626COMPOSITE COLLAGEN PRODUCT AND METHOD OF MAKING THEREOFNovember 2024May 2025Allow611YesNo
18934153FILAMENTOUS FUNGUS AND USE THEREOF IN GAS METABOLISMOctober 2024April 2025Allow510NoNo
18896834PREPARATION METHOD OF PECTIC POLYSACCHARIDE WITH EFFECT OF REGULATING AND CONTROLLING ICE CRYSTAL GROWTHSeptember 2024October 2025Abandon1220YesNo
18850239USE OF FUSARIUM BRACHYGIBBOSUM IN PRODUCTION OF MYCELIAL PROTEINSeptember 2024November 2025Allow1411NoNo
18894673SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSSeptember 2024June 2025Abandon801NoNo
18885661POLYMERASE MUTANT AND APPLICATIONS THEREOFSeptember 2024February 2025Allow510YesNo
18820753BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISAugust 2024January 2025Allow510NoNo
18818465Process, Tube And Device For The Preparation Of Wound Healant CompositionAugust 2024September 2025Allow1320NoNo
18785085PROBIOTICS COMPLEX COMPOSITION WITH IMMUNOMODULATORY AND IMMUNE HOMEOSTASIS PROPERTYJuly 2024February 2026Allow1910NoNo
18755419USE OF LOW pH ACTIVE ALPHA-1,4;/1,6-GLYCOSIDE HYDROLASES (GLCH) AS A FEED ADDITIVE FOR RUMINANTS TO ENHANCE STARCH DIGESTIONJune 2024February 2026Allow2020YesNo
18749228Microbial Lysozyme for use in the Treatment of Irritable Bowel Syndrome or Inflammatory Bowel DiseaseJune 2024February 2026Allow2011NoNo
18744950ALKALINE PHOSPHATASE FORMULATIONSJune 2024August 2025Allow1410NoNo
18739955SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSJune 2024January 2025Allow710NoNo
18735829Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage DisordersJune 2024October 2025Abandon1601NoNo
18732797PREPARING LIVE MICROBIAL SAMPLES AND MICROORGANISMS FOR SUBSEQUENT MASS SPECTROMETRIC MEASUREMENT AND EVALUATIONJune 2024December 2025Allow1820YesNo
18733787Production of Human Milk Oligosaccharides in Microbial Hosts with Engineered Import/ExportJune 2024January 2026Allow1920NoNo
18675254PROBIOTIC COMPOSITION FOR IMPROVING SOY PROTEIN PROTEOLYSIS AND AMINO ACID PRODUCTION ACTIVITYMay 2024January 2026Allow2010NoNo
18673024BACTERIOPHAGES FOR TREATMENT OF TUBERCULOSISMay 2024December 2025Allow1811YesNo
18672898METHOD FOR DECOMPOSING PERACETIC ACID AND METHOD FOR CULTURING MICROORGANISMS USING SAMEMay 2024October 2025Allow1620NoNo
18657338TOBACCO MOSAIC VIRUS DELIVERY OF MITOXANTRONE FOR CANCER THERAPYMay 2024January 2026Abandon2010NoNo
18657510IVALTINOSTAT COMBINATION THERAPY FOR TREATING PANCREATIC CANCERMay 2024October 2025Allow1721NoNo
18656340HUMAN ALPHA-GALACTOSIDASE VARIANTSMay 2024November 2024Allow600YesNo
18654969METHOD FOR PREPARING CULTURES OF LACTIC ACID BACTERIAMay 2024November 2025Allow1911NoNo
18654723PROCESS FOR PRODUCTION OF A SOLUBLE AND INSOLUBLE COLLAGEN PRODUCT FROM MAMMALIAN DERMIS TISSUEMay 2024August 2024Allow411YesNo
18649162MICROBIAL FERMENTATION METHODS AND COMPOSITIONSApril 2024September 2025Allow1720NoNo
18639518BIOCOMPATIBLE CONDITIONED CELL MEDIUM COMPOSITIONS AND USES THEREOFApril 2024February 2026Allow2220NoNo
18637707METHODS FOR QUANTIFYING FRATAXIN ACTIVITYApril 2024May 2025Allow1310YesNo
18637805PROCESSES FOR PRODUCING FERMENTATION PRODUCTSApril 2024January 2026Allow2111NoNo
18636450SYSTEM AND METHOD FOR LIQUID FUEL PRODUCTION FROM CARBONACEOUS MATERIALS USING RECYCLED CONDITIONED SYNGASApril 2024July 2025Allow1512NoNo
18634304ENDOGENOUS LIPASE FOR METAL REDUCTION IN DISTILLERS CORN OILApril 2024November 2025Allow1911YesNo
18634776OLIGOSACCHARIDE DEBRANCHING ENZYME MUTANT AND USE THEREOF IN GLUCOSE MOTHER LIQUORApril 2024April 2025Allow1200YesNo
18632871FILAMENTOUS FUNGAL BIOMATS, METHODS OF THEIR PRODUCTION AND METHODS OF THEIR USEApril 2024April 2025Allow1220NoNo
18631959BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISApril 2024August 2024Allow410NoNo
18629983METHOD FOR PROPHYLAXIS OF INFECTIONS IN CROPS AND ORNAMENTALS, PREFERABLY IN VITICULTURE, AND IN WOODY PLANTSApril 2024October 2025Allow1810YesNo
18628247Distributed Systems for the Efficient Production and Use of Microbe-Based CompositionsApril 2024March 2025Allow1111NoNo
18626855SYSTEMS AND METHODS FOR GROWTH OF INTESTINAL CELLS IN MICROFLUIDIC DEVICESApril 2024March 2025Allow1100NoNo
18627241SPORE-BASED PROBIOTIC SUPPLEMENTATION IN DOGS AND CONTROL OF ENDOTOXEMIAApril 2024April 2025Allow1210NoNo
18615574FILAMENTOUS FUNGAL BIOMATS, METHODS OF THEIR PRODUCTION AND METHODS OF THEIR USEMarch 2024September 2024Allow610YesNo
18602659BACTERIOPHAGE COMPOSITIONS AND METHODS FOR TREATMENT OF BACTERIAL INFECTIONSMarch 2024March 2026Allow2411NoNo
18603016FILAMENTOUS FUNGAL BIOMATS, METHODS OF THEIR PRODUCTION AND METHODS OF THEIR USEMarch 2024October 2025Abandon1901NoNo
18597734Non-Toxic Pest Control Compositions and Methods and Uses ThereofMarch 2024February 2025Allow1210YesNo
18594570EDIBLE PLANT PARTS ENRICHED WITH PROBIOTIC BACTERIAMarch 2024June 2025Allow1510YesNo
18591288METHOD AND COMPOSITIONS FOR INHIBITING OR PREVENTING ADVERSE EFFECTS OF ORAL ANTIBIOTICSFebruary 2024April 2025Abandon1310NoNo
18588956SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSFebruary 2024October 2024Abandon801NoNo
18588987SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSFebruary 2024September 2024Allow710YesNo
18588930SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINSFebruary 2024September 2024Allow710YesNo
18587665Methods of Adding Polymers to Ribonucleic AcidsFebruary 2024February 2025Allow1201YesNo
18581700ISLET CELL MANUFACTURING COMPOSITIONS AND METHODS OF USEFebruary 2024January 2025Allow1100YesNo
18582231PRODUCTION OF CANNABINOIDS IN YEASTFebruary 2024October 2025Abandon2001NoNo
18581245USE OF HSP70 AS A REGULATOR OF ENZYMATIC ACTIVITYFebruary 2024November 2025Allow2111NoNo
18443732METHOD AND KIT FOR CHARACTERIZING DOPAMINERGIC PROGENITOR CELLS OBTAINED BY DIFFERENTIATING PLURIPOTENT STEM CELLSFebruary 2024January 2026Allow2310NoNo
18440808METHODS FOR ENHANCING IMMUNE CHECKPOINT BLOCKADE THERAPY BY MODULATING THE MICROBIOMEFebruary 2024January 2025Allow1121YesNo
18682024METHOD FOR PRODUCING A RECOMBINANT BACTERIAL COLLAGEN-LIKE PROTEIN (CLP)February 2024September 2024Allow710YesNo
18432324ANTIMICROBIAL HEVAMINE A-RELATED COMPOSITIONS AND METHODSFebruary 2024December 2024Allow1011YesNo
18427867Method of Alleviating Obsessive Compulsive Disorder Symptoms by Use of a Multi-Strain Probiotic FormulationJanuary 2024March 2026Allow2510YesNo
18511300APPLICATION OF BACILLUS COAGULANS IN PREPARING MEDICATION FOR IMPROVING FUNCTIONAL DECLINE OF ORGANISMS CAUSED BY HYPERGLYCEMIA AND HYPERLIPIDEMIAJanuary 2024April 2025Abandon1710NoNo
18424277ENGINEERED MEGANUCLEASES SPECIFIC FOR RECOGNITION SEQUENCES IN THE HEPATITIS B VIRUS GENOMEJanuary 2024June 2025Abandon1711NoNo
18423606NOVEL 7Beta-HYDROXYSTEROID DEHYDROGENASE MUTANTS AND PROCESS FOR THE PREPARATION OF URSODEOXYCHOLIC ACIDJanuary 2024August 2025Abandon1910YesNo
18422022METHOD FOR REGULATING BLOOD GLUCOSE, LOSING WEIGHT, AND REDUCING PRODUCTION OF ADVANCED GLYCATION END PRODUCTS BY USING SACCHAROMYCES CEREVISIAE TCI907 OR SUPERNATANT THEREOFJanuary 2024August 2025Allow1911YesNo
18421847SUSPENSION CULTURE OF HUMAN EMBRYONIC STEM CELLSJanuary 2024June 2025Allow1730YesNo
18419725COMPOSITION OF STIMULATING IMMUNITY COMPRISING LACTOBACILLUS RHAMNOSUS LM1019 AND STARTER STRAINSJanuary 2024December 2025Allow2310NoNo
18419326METHOD FOR THE PRODUCTION OF A DAIRY FOOD PRODUCT AND A METHOD FOR GENE TRANSFER BY CONJUGATIONJanuary 2024November 2025Abandon2210NoNo
18417268Anaerobic Blood Storage and Pathogen Inactivation MethodJanuary 2024March 2025Allow1410NoNo
18417981METHODS OF PROCESSING MUNICIPAL SOLID WASTE (MSW) USING MICROBIAL HYDROLYSIS AND FERMENTATIONJanuary 2024April 2025Abandon1501NoNo
18411888MULTIUSE, ENZYMATIC DETERGENT AND METHODS OF STABILIZING A USE SOLUTIONJanuary 2024November 2024Allow1010YesNo
18409148METHOD FOR QUANTIFYING AT LEAST ONE MICROORGANISM GROUP VIA MASS SPECTROMETRYJanuary 2024June 2025Allow1711NoNo
18408245METHOD OF USING/APPLYING A KERATIN HYDROLYSIS PEPTIDE SOLUTION TO IMPROVE THE FERTILIZER USAGE EFFICIENCY IN SOYBEANJanuary 2024October 2025Allow2200NoNo
18407334DETERGENT COMPOSITIONS COMPRISING BACTERIAL MANNANASESJanuary 2024June 2025Allow1710NoNo
18406008TREATMENT OF VON WILLEBRAND DISEASEJanuary 2024January 2025Allow1210NoNo
18405193PROTEASE VARIANTS AND USES THEREOFJanuary 2024October 2025Abandon2120YesNo
18403646MEDIA FOR STEM CELL PROLIFERATION AND INDUCTIONJanuary 2024September 2025Abandon2111NoNo
18394616RUMINANT COMPOSITIONSDecember 2023April 2025Abandon1610NoNo
18389801METHOD FOR THE PRODUCTION OF THYMOCYTE SUPERNATANTDecember 2023September 2025Allow2110NoNo
18391409PDE5A DESTABILIZING DOMAINSDecember 2023April 2025Abandon1510NoNo
18544083BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISDecember 2023April 2024Allow410NoNo
18544275FUSION CONSTRUCTS AS PROTEIN OVER-EXPRESSION VECTORSDecember 2023April 2025Allow1610YesNo
18540631PROCESS FOR PRODUCTION OF SUGAR FROM A COTTON-CONTAINING TEXTILEDecember 2023March 2025Abandon1511NoNo
18534962MICROBIOME PROTECTION FROM ORAL ANTIBIOTICSDecember 2023December 2024Allow1210NoNo
18535652GLYCAN THERAPEUTIC COMPOSITIONS AND RELATED METHODS THEREOFDecember 2023June 2025Allow1810NoNo
18568959A METHOD OF CELL LYSISDecember 2023May 2025Allow1710YesNo
18568297MICROALGAE STRAIN CHLORELLA SP. VADA 2020December 2023August 2025Abandon2010NoNo
18530082ENGINEERED SYNTHASE FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES AND INTRANSIGENT SUBSTRATESDecember 2023April 2025Allow1611YesNo
18526930COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTIONDecember 2023April 2025Allow1611YesNo
18524884MOLECULES AND METHODS FOR ITERATIVE POLYPEPTIDE ANALYSIS AND PROCESSINGNovember 2023August 2025Allow2002YesNo
18519620POLYMERASE ENZYME FROM 9°NNovember 2023March 2025Abandon1610NoNo
18517905Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering ThemNovember 2023January 2026Abandon2611NoNo
18515559Pharmaceutical Composition of a Recombinant Adeno-Associated Virus Vector and its ApplicationNovember 2023May 2025Allow1832NoNo
18514032DIAGNOSTIC AGENT AND MEDICINE COMPRISING ADAMTS13 AS MAIN INGREDIENTNovember 2023August 2025Abandon2120NoNo
18513988Treatment Method and Product for Uterine Fibroids using Purified CollagenaseNovember 2023December 2025Abandon2520NoNo
18513267ACCELERATED DIRECTED EVOLUTION OF MICROBIAL CONSORTIA FOR THE DEVELOPMENT OF DESIRABLE PLANT PHENOTYPIC TRAITSNovember 2023July 2025Allow2020NoNo
18513343HISTOLOGICAL SPECIMEN TREATMENTNovember 2023January 2026Abandon2630NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1651.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
261
Examiner Affirmed
183
(70.1%)
Examiner Reversed
78
(29.9%)
Reversal Percentile
37.1%
Lower than average

What This Means

With a 29.9% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
1445
Allowed After Appeal Filing
316
(21.9%)
Not Allowed After Appeal Filing
1129
(78.1%)
Filing Benefit Percentile
9.6%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 21.9% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

⚠ Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

⚠ Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Art Unit 1651 - Prosecution Statistics Summary

Executive Summary

Art Unit 1651 is part of Group 1650 in Technology Center 1600. This art unit has examined 14,593 patent applications in our dataset, with an overall allowance rate of 52.4%. Applications typically reach final disposition in approximately 35 months.

Comparative Analysis

Art Unit 1651's allowance rate of 52.4% places it in the 8% percentile among all USPTO art units. This art unit has a significantly lower allowance rate than most art units at the USPTO.

Prosecution Patterns

Applications in Art Unit 1651 receive an average of 2.07 office actions before reaching final disposition (in the 65% percentile). The median prosecution time is 35 months (in the 29% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more challenging examination environment compared to the USPTO average.
  • With more office actions than average, plan for relatively streamlined prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.