USPTO Examiner BERKE SCHLESSEL DAVID W - Art Unit 1651

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19089650ELECTROPORATION-TARGETED DELIVERY OF RIBOSOME INACTIVATING PROTEIN GELONIN INTO MAMMALIAN CELLSMarch 2025October 2025Allow610NoNo
18820753BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISAugust 2024January 2025Allow510NoNo
18639518BIOCOMPATIBLE CONDITIONED CELL MEDIUM COMPOSITIONS AND USES THEREOFApril 2024February 2026Allow2220NoNo
18631959BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISApril 2024August 2024Allow410NoNo
18626855SYSTEMS AND METHODS FOR GROWTH OF INTESTINAL CELLS IN MICROFLUIDIC DEVICESApril 2024March 2025Allow1100NoNo
18581700ISLET CELL MANUFACTURING COMPOSITIONS AND METHODS OF USEFebruary 2024January 2025Allow1100YesNo
18581245USE OF HSP70 AS A REGULATOR OF ENZYMATIC ACTIVITYFebruary 2024November 2025Allow2111NoNo
18389801METHOD FOR THE PRODUCTION OF THYMOCYTE SUPERNATANTDecember 2023September 2025Allow2110NoNo
18544083BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISDecember 2023April 2024Allow410NoNo
18535652GLYCAN THERAPEUTIC COMPOSITIONS AND RELATED METHODS THEREOFDecember 2023June 2025Allow1810NoNo
18515559Pharmaceutical Composition of a Recombinant Adeno-Associated Virus Vector and its ApplicationNovember 2023May 2025Allow1832NoNo
18497412BIFIDOBACTERIA FOR TREATING CARDIAC CONDITIONSOctober 2023August 2025Abandon2210NoNo
18378133TWO-STAGE PROCESS FOR PRODUCING OIL FROM MICROALGAEOctober 2023June 2025Abandon2010NoNo
18476483METHODS AND COMPOSITIONS FOR PRESERVING BACTERIASeptember 2023July 2025Allow2120YesNo
18454562COMPOSITION FOR PROMOTING THE GROWTH OF LACTIC ACID BACTERIA COMPRISING GROWTH FACTORSAugust 2023October 2024Allow1410NoNo
18230923COMPOSITIONS AND METHODS FOR TREATING RETINAL DISEASESAugust 2023May 2025Allow2110NoNo
18343514BONE MARROW MICROFLUIDIC DEVICES AND METHODS FOR PREPARING AND USING THE SAMEJune 2023August 2024Allow1410NoNo
18338437Quality Assurance of ChondrocytesJune 2023November 2024Allow1710NoNo
18337292STEM CELL CULTURE SYSTEMS FOR COLUMNAR EPITHELIAL STEM CELLS, AND USES RELATED THERETOJune 2023March 2025Allow2111NoNo
18334098ACTIVATION OF IMMUNE CELLSJune 2023September 2024Abandon1610NoNo
18039848METHOD OF ENCAPSULATING SINGLE CELLS UTILIZING AN ALTERNATING CURRENT ELECTROSPRAYJune 2023September 2025Allow2700NoNo
18202419STABILIZATION OF THROMBOCYTES AT AMBIENT TEMPERATURESMay 2023June 2024Allow1310NoNo
18300427Scheduled FeedApril 2023April 2024Allow1210YesNo
18127958METHODS AND MATERIALS FOR USING FIBRIN SUPPORTS FOR RETINAL PIGMENT EPITHELIUM TRANSPLANTATIONMarch 2023August 2024Allow1610YesNo
18043405HYDROGELS FOR CELL CULTUREFebruary 2023February 2026Abandon3501NoNo
18175417QUANTIFYING CELL-DERIVED CHANGES IN COLLAGEN SYNTHESIS, ALIGNMENT, AND MECHANICS IN A 3D CONNECTIVE TISSUE MODELFebruary 2023June 2025Allow2810YesNo
18175433METHODS AND COMPOSITIONS FOR INCREASING SUSCEPTIBILITY TO RADIATION TREATMENT BY INHIBITING SUPPRESSION OF NUMERICAL CHROMOSOMAL INSTABILITY OF CANCER CELLSFebruary 2023June 2024Allow1610NoNo
18167728DISORDERS IMPLICATING PUFA OXIDATIONFebruary 2023July 2024Allow1710NoNo
18101727METHODS OF MANUFACTURE OF THERAPEUTIC PRODUCTS COMPRISING VITALIZED PLACENTAL DISPERSIONSJanuary 2023January 2025Allow2410NoNo
18100671Ex vivo tumour immune microenvironment model, a method for preserving a tumour-specific immune cell profile in an ex vivo tumour immune microenvironment model and use of nanofibrillar celluloseJanuary 2023March 2026Abandon3810NoNo
18155311METHOD FOR THE RAPID DETECTION OF BACTERIAL SPORES IN AN INDUSTRIAL PROCESSJanuary 2023August 2025Allow3130NoNo
18097414DENTAL DEVICE FOR TOOTH WHITENINGJanuary 2023March 2025Allow2630NoNo
18015972METHODS FOR EVALUATING CARDIAC SAFETY OF DRUG USING CARDIOMYOCYTES DERIVED FROM HUMAN STEM CELLSJanuary 2023November 2025Allow3410NoNo
18153320NASAL FOAM VIA CRIBRIFORM PLATE FOR MEDICATION DELIVERY TO THE BRAIN AND/OR BODY AND FOR NASAL MOISTURIZATION AND HYGIENEJanuary 2023December 2024Abandon2320NoNo
18094883COMPOSITION WITH A TIME RELEASE MATERIAL FOR REMOVING HALOGENATED HYDROCARBONS FROM CONTAMINATED ENVIRONMENTSJanuary 2023February 2024Allow1310NoNo
18147948PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF PROBIOTIC AND PREBIOTIC TO TREAT STUNTINGDecember 2022November 2025Abandon3420NoYes
18147939CELL CULTURE SUBSTRATE, CANCER CELL AGGREGATE AND METHOD FOR MANUFACTURING SAME USING SAID SUBSTRATE, AND DRUG SCREENING METHOD USING SAID CANCER CELL AGGREGATEDecember 2022February 2026Abandon3701NoNo
18146108METHOD OF SCREENING FOR A SUBSTANCE THAT ACTS ON A CELL MASSDecember 2022September 2023Allow800NoNo
18065480METHODS, CULTURE MEDIAS AND DEVICES FOR GENERATING EMBRYOS IN VITRO FROM STEM CELLSDecember 2022December 2025Allow3610YesNo
17926102Preparation and Purification of Hypersialylated IGGNovember 2022February 2026Allow3911NoNo
17925943DETERMINING DRUG EFFECTS USING COMBINATION OF MEASUREMENTSNovember 2022December 2025Abandon3710NoNo
17925998STABLY-INVERTED ORGANOIDS AND METHODS OF PRODUCING AND USING THE SAMENovember 2022November 2025Allow3610NoNo
17924646A HEPATITIS C NUCLEIC ACID VACCINE COMPRISING A VARIABLE DOMAIN DELETED E2 POLYPEPTIDENovember 2022February 2026Abandon4010NoNo
17921888CONFORMAL COATING OF CELLS FOR IMMUNOISOLATIONOctober 2022November 2025Allow3610NoNo
17973909HUMAN ORIGIN PROBIOTIC LACTOBACILIUS RHAMNOSUS HL-200 TO REDUCE LEAKY GUT BY METABOLIZING ETHANOLAMINEOctober 2022June 2025Allow3141NoNo
17971686METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONOctober 2022May 2024Abandon1910NoNo
17996611ADENO-ASSOCIATED VIRUS WITH ENGINEERED CAPSIDOctober 2022June 2025Allow3200NoNo
17961276METHOD FOR TARGETED REGULATION OF SOIL MICROBES TO SYNCHRONIZE HEAVY METAL/METALLOID TRANSFORMATION AND GREENHOUSE GAS EMISSION REDUCTION AND USEOctober 2022August 2023Allow1010NoNo
17995543PCR BASED DIAGNOSTIC KIT, COMPOSITIONS AND METHODS FOR AMPLIFICATION AND DETECTION OF SARS-COV-2October 2022February 2026Abandon4010NoNo
17916369CORONAVIRUS VACCINESSeptember 2022November 2025Allow3810NoNo
17914319METHODS, OLIGONUCLEOTIDES, AND KITS FOR DETECTION AND TREATMENT OF CORONAVIRUSSeptember 2022January 2026Allow4011NoNo
17934460STIMULATION OF MESENCHYMAL STEM CELL THERAPEUTIC ACTIVITIES BY T REGULATORY CELLSSeptember 2022May 2024Allow1910NoNo
17950446Nerve Guidance Conduit Comprising Neural Crest Stem-Like Cells and/or Schwann Cell Precursor-Like Cells and Methods of Making and Using the SameSeptember 2022January 2026Allow4011NoNo
17906645HEART TISSUE MODELSeptember 2022February 2026Allow4111YesNo
17905873RAPID SCREEN FOR ANTIBIOTIC RESISTANCE AND TREATMENT REGIMENSeptember 2022January 2026Allow4020NoNo
17822860METHODS AND COMPOSITIONS FOR PRESERVING BACTERIAAugust 2022June 2023Allow1000NoNo
17886274BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITISAugust 2022January 2024Allow1710NoNo
17798824METHOD AND DRUG FOR TREATING VIRAL PNEUMONIAAugust 2022February 2026Abandon4211NoNo
17861912METHODS FOR TREATING INFLAMMATORY CONDITIONS OF THE LUNGSJuly 2022October 2025Abandon3910NoNo
17861764PROCESS FOR PRODUCING PLATELET-RICH FIBRIN MATRIX FROM PLATELET-RICH PLASMAJuly 2022July 2025Abandon3610NoNo
17856121NON-PROTEIN CLOSTRIDIAL TOXIN COMPOSITIONSJuly 2022March 2024Abandon2110NoNo
17788514COMPOSITION CONTAINING SESAMIN AND PQQJune 2022July 2025Allow3610NoNo
17842610METHODS AND COMPOSITIONS TO PROMOTING RETINAL REGENERATION USING PROX1 MIGRATION INHIBITOR AS ACTIVE INGREDIENTJune 2022January 2026Allow4320NoNo
17786256LON PROTEASE, ALPHA-HEMOLYSIN, CK1-ALPHA-1; C-MYB INHIBITOR OR A CEBP-DELTA INHIBITOR AS THERAPEUTICSJune 2022November 2025Abandon4111NoNo
17778328ARCHAEAL PEPTIDE RECOMBINASE - A NOVEL PEPTIDE LIGATING ENZYMEMay 2022December 2025Allow4331YesNo
17747322ANTIBODY CONJUGATED NANOPARTICLE ASSAY AND TREATMENT FOR SARS-CoV-2May 2022May 2025Abandon3601NoNo
17727323BIOCOMPATIBLE CONDITIONED CELL MEDIUM COMPOSITIONS AND USES THEREOFApril 2022January 2024Allow2110NoNo
17770451METHODS AND SYSTEMS FOR PERFORMING PERFUSION CELL CULTUREApril 2022July 2025Allow3911NoNo
17721604CROSSLINKED SOFT TISSUE GRAFT AND METHODS OF USE THEREOFApril 2022March 2024Allow2310NoNo
17659021Soluble Intein Fusion Proteins And Methods For Purifying BiomoleculesApril 2022January 2024Allow2220NoNo
17763171METHOD FOR CULTURING HAEMATOCOCCUS PLUVIALIS TO PRODUCE ASTAXANTHINMarch 2022December 2024Allow3321NoNo
17688189USE OF HSP70 AS A REGULATOR OF ENZYMATIC ACTIVITYMarch 2022December 2023Allow2110NoNo
17678634MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTIONFebruary 2022October 2023Allow2010NoNo
17678485SYSTEMS AND METHODS FOR GROWTH OF INTESTINAL CELLS IN MICROFLUIDIC DEVICESFebruary 2022November 2023Allow2120NoNo
17677727TUMORICIDAL AND ANTIMICROBIAL COMPOSITIONS AND METHODSFebruary 2022April 2024Allow2621NoNo
17672443ASSAYS FOR IMPROVING AUTOMATED ANTIMICROBIAL SUSCEPTIBILITY TESTING ACCURACYFebruary 2022July 2023Allow1710NoNo
17634876YEAST HAVING IMPROVEMENT OF LACTIC ACID TOLERANCE AND USE THEREOFFebruary 2022February 2024Allow2420NoNo
17666034BIFIDOBACTERIA FOR TREATING CARDIAC CONDITIONSFebruary 2022November 2023Abandon2110NoNo
17310418THREE-DIMENSIONAL CULTURE METHOD FOR LARGE-SCALE PREPARATION OF STEM CELLSFebruary 2022April 2025Allow4511YesNo
1758966721-Hydroxylation of SteroidsJanuary 2022December 2023Allow2320NoNo
17576349Methods for Preparing Data from Tissue Sections for Machine Learning Using Both Brightfield and Fluorescent ImagingJanuary 2022September 2025Abandon4410NoNo
17645423NOVEL CAMPYLOBACTER BACTERIOPHAGES AND USES THEREOFDecember 2021May 2025Allow4131YesNo
17556650COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VIRAL INFECTIONSDecember 2021June 2025Abandon4210NoNo
17619722METHOD FOR STABILIZING INTRACELLULAR RNADecember 2021September 2025Allow4511NoNo
17542551METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONDecember 2021June 2022Allow620NoNo
17542568METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONDecember 2021April 2022Allow410NoNo
17542552METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONDecember 2021March 2022Allow410NoNo
17542599METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONDecember 2021May 2022Allow610NoNo
17542570METHODS AND SYSTEMS FOR IN-VITRO MILK PRODUCTIONDecember 2021May 2022Allow610NoNo
17539155TUMORICIDAL AND ANTIMICROBIAL COMPOSITIONS AND METHODSNovember 2021January 2024Allow2610NoNo
17534977ISOLATED HUMAN LUNG PROGENITOR CELLS AND USES THEREOFNovember 2021January 2024Allow2620NoNo
17610129METHOD FOR EXTRACTING USEFUL SUBSTANCES FROM SHRIMP SHELLSNovember 2021January 2025Allow3810NoNo
17594570Genetically Encoded Tyrosine Sulfation of Proteins in EukaryotesOctober 2021July 2025Allow4521NoNo
17602271LABEL-FREE DETECTION OF MYCOBACTERIA USING SURFACE ENHANCED RAMAN SPECTROSCOPYOctober 2021March 2025Abandon4110NoNo
17495411XENO-FREE GENERATION OF TISSUE-SPECIFIC PROGENITOR CELLSOctober 2021September 2024Allow3520YesYes
17472737METHOD FOR PURIFYING AND QUANTIFYING THROMBIN AND ITS DEGRADATION POLYPEPTIDESSeptember 2021March 2025Allow4220NoNo
17436148ANTIBACTERIAL COMPOSITION AGAINST DRUG-RESISTANT BACTERIA OR PRO-INFLAMMATORY BACTERIASeptember 2021May 2025Abandon4511NoNo
17461347VEHICLES FOR APPLYING BACTERIA TO SKIN, SCALP, AND HAIRAugust 2021April 2025Allow4320YesNo
17434885BIOLOGICAL WATER-QUALITY DETECTION METHOD USING OBSTRUCTIVE MULTI-MODULE BIOLOGICAL WATER-QUALITY DETECTION DEVICEAugust 2021October 2024Allow3710NoNo
17445975FEED AND FOODAugust 2021November 2024Allow3810YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner BERKE-SCHLESSEL, DAVID W.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
17
Examiner Affirmed
8
(47.1%)
Examiner Reversed
9
(52.9%)
Reversal Percentile
80.3%
Higher than average

What This Means

With a 52.9% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
62
Allowed After Appeal Filing
12
(19.4%)
Not Allowed After Appeal Filing
50
(80.6%)
Filing Benefit Percentile
23.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 19.4% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner BERKE-SCHLESSEL, DAVID W - Prosecution Strategy Guide

Executive Summary

Examiner BERKE-SCHLESSEL, DAVID W works in Art Unit 1651 and has examined 696 patent applications in our dataset. With an allowance rate of 65.2%, this examiner has a below-average tendency to allow applications. Applications typically reach final disposition in approximately 31 months.

Allowance Patterns

Examiner BERKE-SCHLESSEL, DAVID W's allowance rate of 65.2% places them in the 26% percentile among all USPTO examiners. This examiner has a below-average tendency to allow applications.

Office Action Patterns

On average, applications examined by BERKE-SCHLESSEL, DAVID W receive 1.99 office actions before reaching final disposition. This places the examiner in the 50% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by BERKE-SCHLESSEL, DAVID W is 31 months. This places the examiner in the 54% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +37.0% benefit to allowance rate for applications examined by BERKE-SCHLESSEL, DAVID W. This interview benefit is in the 85% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 30.2% of applications are subsequently allowed. This success rate is in the 59% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 35.3% of cases where such amendments are filed. This entry rate is in the 53% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 87.5% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 66% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 66.7% of appeals filed. This is in the 47% percentile among all examiners. Of these withdrawals, 58.8% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 70.5% are granted (fully or in part). This grant rate is in the 77% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.3% of allowed cases (in the 55% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.