USPTO Art Unit 1678 Prosecution Statistics

Art Unit Information

Art Unit: 1678
Group: 1670
Tech Center: 1600
Total Cases: 4,226
Last Active: October 2024

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18923470BIOMOLECULE DETECTION METHOD USING DIFFUSION ORDERED SPECTROSCOPYOctober 2024April 2025Allow510YesNo
18789799RAPID DETECTION METHOD FOR RICIN TOXINJuly 2024December 2024Allow510YesNo
18769708ASSAY METHOD OF ANTIBODYJuly 2024March 2025Allow810NoNo
18752739METHOD FOR DETECTING AFLATOXIN B1 CONTENT USING FLUORESCENCE ANALYSIS BASED ON OPTICAL SECTIONINGJune 2024September 2024Allow200YesNo
18722997MAGNETIC CHEMILUMINESCENCE IMMUNOASSAY KIT BASED ON BIFUNCTIONAL FUSION PROTEIN FOR MYCOTOXINS, AND USE THEREOFJune 2024March 2025Allow911YesNo
18679192COMPOSITION COMPRISING AFLIBERCEPT AND A VARIANT THEREOF, AND RELATED METHODS AND USESMay 2024November 2024Allow501YesNo
18674179Bead-based analysis of a sampleMay 2024January 2025Allow810YesNo
18661576TUBERCULOSIS DETECTION KITMay 2024January 2025Allow820YesNo
18642104ULTRA-SENSITIVE DETECTION OF MOLECULES OR PARTICLES USING BEADS OR OTHER CAPTURE OBJECTSApril 2024September 2024Allow501NoNo
18621418Means and Methods for the Determination of the Biological Activity of Neurotoxin Polypeptides in CellsMarch 2024February 2025Allow1100YesNo
18616550DETECTION OF ANTI-p53 ANTIBODIESMarch 2024January 2025Allow1010NoNo
18585679METHOD OF DETERMINING AN IMMUNOGENIC RESPONSE CHARACTERISTIC OF A CHEMICAL SUBSTANCEFebruary 2024March 2025Allow1320YesNo
18437439NON-INVASIVE CANCER DETECTION AND ANALYSIS BY SINGLE-MOLECULE IMAGINGFebruary 2024March 2025Allow1400NoNo
18438105SPACING LINKER GROUP DESIGN FOR BRIGHTNESS ENHANCEMENT IN DIMERIC OR POLYMERIC DYESFebruary 2024July 2025Allow1721YesNo
18436594ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPSFebruary 2024April 2025Allow1420YesNo
18434947LATERAL FLOW TESTINGFebruary 2024May 2025Allow1511NoNo
18432995MARKERS FOR RENAL DISEASEFebruary 2024November 2024Allow910YesNo
18414438Compositions and Methods for Identifying and Modulating Metabolic HealthJanuary 2024June 2025Abandon1701NoNo
18414339KITS AND METHODS TO DISTINGUISH FALSE LABOR AND TRUE LABORJanuary 2024December 2024Allow1120NoNo
18412596METHOD FOR ACCURATE DIAGNOSIS OF A DISEASE TARGETING BIOMARKERS IN LIQUID BIOPSYJanuary 2024January 2025Allow1310YesNo
18406399METHODS FOR DIAGNOSING SYSTEMIC LUPUS ERYTHEMATOSUSJanuary 2024April 2025Allow1520YesNo
18405536Bed Bugs Detection DeviceJanuary 2024August 2024Allow700YesNo
18401919REPORTER PROTEIN FUSED ANTIBODIESJanuary 2024June 2025Abandon1701NoNo
18392925IMMUNO-BASED RETARGETED ENDOPEPTIDASE ACTIVITY ASSAYSDecember 2023April 2025Abandon1510NoNo
18544491METHOD FOR STABILIZING EXTRACELLULAR VESICLESDecember 2023March 2025Allow1511YesNo
18526139THERAPEUTIC PROTEIN SELECTION IN SIMULATED IN VIVO CONDITIONSDecember 2023May 2025Abandon1711NoNo
18514615BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATESNovember 2023February 2025Abandon1510NoNo
18486086ANTIBODIES TO TIGITOctober 2023May 2025Allow1911YesNo
184855751,1 '-[[(SUBSTITUTED ALKYL)IMINO]BIS(ALKYLENE)]BIS-FERROCENES AND THEIR USE IN ELECTROCHEMICAL ASSAYS BY LABELLING SUBSTRATES OF INTERESTOctober 2023June 2024Allow800YesNo
18482286KITS AND METHODS FOR PREDICTION AND TREATMENT OF PREECLAMPSIAOctober 2023November 2024Allow1410YesNo
18467302ADRENOMEDULLIN ASSAYS AND METHODS FOR DETERMINING MATURE ANDRENDOMEDULLINSeptember 2023November 2024Allow1410YesNo
18367986HEALTH TEST FOR A BROAD SPECTRUM OF HEALTH PROBLEMSSeptember 2023March 2025Allow1820YesNo
18367823METHODS FOR DIAGNOSING SYSTEMIC LUPUS ERYTHEMATOSUSSeptember 2023October 2023Allow110NoNo
18242804Highly Sensitive System and Method for Analysis of TroponinSeptember 2023June 2025Allow2210NoNo
18243045SYSTEMS AND METHODS FOR TESTING AND SCREENING USING COMPOUND BOUND SUBSTRATESSeptember 2023November 2024Allow1521YesNo
18460944IL-7 Binding Proteins and Their Use in Medical TherapySeptember 2023May 2024Allow900NoNo
18459908METHODS FOR ASSESSING MUCOSAL HEALING IN INFLAMMATORY BOWEL DISEASE PATIENTSSeptember 2023May 2025Allow2130YesNo
18453745TARGET-BINDING ACTIVATED SPLIT REPORTER SYSTEMS FOR ANALYTE DETECTION AND RELATED COMPONENTS AND METHODSAugust 2023November 2024Allow1510NoNo
18452504METHODS AND COMPOSITIONS FOR SYNTHETIC BIOMARKERSAugust 2023June 2025Allow2241YesNo
18364392SUBSTANCE LABELING PATCH, METHOD AND APPARATUS FOR TISSUE DIAGNOSIS USING THE SAMEAugust 2023August 2024Allow1210YesNo
18227151ELISA FOR DIAGNOSIS OF HAEMONCHUS LONGISTIPES INFECTION IN CAMELSJuly 2023February 2024Allow620YesNo
18227030ELISA FOR DIAGNOSIS OF HAEMONCHUS LONGISTIPES INFECTION IN CAMELSJuly 2023December 2023Allow520YesNo
18353683COMPOSITIONS AND METHODS FOR ASSAYING PLATELET REACTIVITY AND TREATMENT SELECTIONJuly 2023December 2024Allow1710YesNo
18351796CONTACT-TYPE PATCH, STAINING METHOD USING THE SAME, AND MANUFACTURING METHOD THEREOFJuly 2023September 2024Allow1410YesNo
18350764SERUM METABOLIC BIOMARKERS FOR DETECTING TUBERCULOSIS AND TUBERCULOSIS DETECTION KITJuly 2023February 2025Allow1911YesNo
18348201NUCLEIC ACID-TAGGED COMPOSITIONS AND METHODS FOR MULTIPLEXED PROTEIN-PROTEIN INTERACTION PROFILINGJuly 2023August 2024Allow1420YesNo
18341440METHOD FOR DETECTION OF ANALYTES VIA POLYMER COMPLEXESJune 2023February 2025Allow2020NoNo
18340791IMMUNOASSAY CONTROLS AND THE USE THEREOFJune 2023June 2024Allow1210YesNo
18340235ADRENOMEDULLIN ASSAYS AND METHODS FOR DETERMINING MATURE ANDRENDOMEDULLINJune 2023October 2024Allow1610YesNo
18339066DIAGNOSTIC METHODS FOR CARDIOVASCULAR DISEASESJune 2023July 2024Allow1310YesNo
18335477ANTI-GPC3 ANTIBODYJune 2023June 2024Allow1210YesNo
18209814REAGENT COMPOSITION FOR DETECTION OF NON-HEMATOPOIETIC TUMOR AND USE THEREOFJune 2023July 2024Allow1311YesNo
18330550METHODS OF DETECTING ANTI-LEPTIN NEUTRALIZING ANTIBODIESJune 2023May 2025Abandon2310YesNo
18204311COMPOSITIONS AND METHODS FOR PLASMAPHERESISMay 2023March 2025Allow2131YesNo
18200301Bead-based analysis of a sampleMay 2023February 2024Allow910YesNo
18317488ULTRA-FAST AND HIGHLY-SENSITIVE CHEMILUMINESCENT IMMUNOASSAY METHOD FOR DETECTING THYROID STIMULATING HORMONEMay 2023April 2024Allow1120NoNo
18315230SYSTEMS AND METHODS TO IDENTIFY AND TREAT SUBJECTS AT RISK FOR OBSTETRICAL COMPLICATIONSMay 2023January 2025Allow2011NoNo
18311856IMMUNE CELLS HAVING CO-EXPRESSED SHRNAS AND LOGIC GATE SYSTEMSMay 2023March 2024Allow1111YesNo
18141767METHODS OF POLYPEPTIDE IDENTIFICATION AND COMPOSITIONS THEREFORMay 2023May 2025Abandon2410NoNo
18308219SELECTIVE OPTICAL DETECTION OF ORGANIC ANALYTES IN LIQUIDSApril 2023October 2023Allow510NoNo
18139242MAGNETIC REMOVAL OR IDENTIFICATION OF DAMAGED OR COMPROMISED CELLS OR CELLULAR STRUCTURESApril 2023February 2025Allow2210NoNo
18304934NOVEL BIOMARKER OF ACUTE CORONARY SYNDROMESApril 2023November 2024Abandon1911NoNo
18127933Methods, Devices, and Systems for Detecting AnalytesMarch 2023August 2024Allow1610YesNo
18187421METHODS FOR PREDICTING RESPONSE TO TREATMENTMarch 2023July 2024Allow1620YesNo
18124224METHOD FOR LABELING INTRACELLULAR AND EXTRACELLULAR TARGETS OF LEUKOCYTESMarch 2023May 2025Allow2611YesNo
18123777DIGITAL AFFINITY LINKAGE ASSAYMarch 2023January 2025Allow2210NoNo
18186899ANTIBODIES TO METHOTREXATE AND USES THEREOFMarch 2023July 2024Allow1621YesNo
18120887SYSTEM AND METHOD FOR SAMPLE PRESERVATIONMarch 2023August 2024Allow1711YesNo
18182199Conjugation Reagents and Methods Using 1,2-CyclohexanedionesMarch 2023May 2025Allow2600YesNo
18115264Glycan Analysis and ProfilingFebruary 2023April 2024Abandon1300NoNo
18114130METHOD AND SYSTEM FOR BUOYANT-PARTICLE-ASSISTED CELL THERAPYFebruary 2023November 2024Allow2111YesNo
18173604Type X Collagen Assays and Methods of Use ThereofFebruary 2023October 2024Abandon2010NoNo
18170852Methods for isolating target cells from bloodFebruary 2023February 2025Abandon2410NoNo
18170481QUANTITATION OF FUNCTIONAL GROUPS ON SOLID SUPPORTSFebruary 2023October 2024Allow2021YesNo
18110229METHODS FOR DIAGNOSING SYSTEMIC LUPUS ERYTHEMATOSUSFebruary 2023July 2023Allow510NoNo
18167557INDICATOR-BASED ANALYSIS OF A SAMPLEFebruary 2023June 2024Allow1621YesNo
18164058HIGHLY SENSITIVE PARTICLE ENHANCED ASSAY FOR THE QUANTIFICATION OF NT-PROBNPFebruary 2023November 2024Abandon2210NoNo
18164275IMMUNOASSAYS FOR HIGH POSITIVELY CHARGED PROTEINSFebruary 2023June 2025Allow2910YesNo
18105582COMPOSITIONS AND METHODS FOR PASSIVE OPTICAL BARCODING FOR MULTIPLEXED ASSAYSFebruary 2023March 2025Allow2510YesNo
18102088METHODS OF DIAGNOSING AND TREATING LUNG CANCERJanuary 2023January 2025Allow2420NoNo
18158753PRETREATMENT AGENT IN NON-AGGLUTINATION ASSAYSJanuary 2023July 2024Allow1810NoNo
18099177Tagged Compounds for Detection and Assay of Small MoleculesJanuary 2023April 2024Abandon1521NoNo
18098193BDNF QUANTITATIVE IMMUNOCHROMATOGRAPHIC TEST STRIP AND PREPARATION METHOD THEREOFJanuary 2023November 2024Abandon2220NoNo
18069456RABIES VIRUS MONOCLONAL ANTIBODY 2F2 AND UNIVERSAL RABIES VIRUS ANTIBODY RAPID DETECTION TEST PAPERDecember 2022September 2024Allow2010NoNo
18068047Detection and Quantification of AKT-mTOR Pathway ProteinsDecember 2022October 2024Allow2211YesNo
18067622BIOMARKERS FOR DIAGNOSING IMPLANT RELATED RISK OF IMPLANT REVISION DUE TO ASEPTIC LOOSENINGDecember 2022July 2024Allow1910YesNo
18079986KINETIC IMMUNOASSAY SYSTEMS AND METHODSDecember 2022June 2023Allow610NoNo
18077673ANTI-DRUG ANTIBODY ASSAYDecember 2022May 2025Abandon2921NoNo
18076940SYSTEMS AND METHODS FOR CELL CULTURE DEVICE INTERCONNECTION AND FLUIDIC DEVICE INTERCONNECTIONDecember 2022January 2024Abandon1310NoNo
18072304CONJUGATED POLYMERS AND METHODS OF USENovember 2022May 2025Allow3001YesNo
17994029MARKER AND PRODUCT FOR AUXILIARY DIAGNOSIS OF VALVULAR HEART DISEASE (VHD)November 2022April 2024Abandon1721YesNo
18058683MICROVESICLE HISTONE H2AX AS A BIOMARKER FOR GENOTOXIC STRESSNovember 2022May 2025Abandon3020NoNo
17992664Analyte Test Strip Assays, and Test Strips and Kits for Use in Practicing the SameNovember 2022February 2025Abandon2711NoNo
17989895MONOCLONAL ANTIBODIES WITH SPECIFICITY FOR FETAL ERYTHROID CELLSNovember 2022March 2025Abandon2820NoNo
17998361ASSAYS FOR THE DETECTION OF A BLOCKING ANALYTENovember 2022November 2024Abandon2401NoNo
18053028Immunoassay for Detecting Zika Virus InfectionNovember 2022September 2024Abandon2210NoNo
18052661FLOW CYTOMETRY EVALUATION OF BIOLOGICAL MATERIAL FOR UNASSOCIATED VIRUS-SIZE PARTICLESNovember 2022November 2024Allow2411YesNo
18050640APPLICATION OF THBS1 PROTEIN AND THBS3 PROTEIN AS BIOMARKERS FOR DETECTING ACUTE MYOCARDIAL INFARCTIONOctober 2022February 2025Abandon2731NoNo
18049773DETECTION OF PAR IN THE CSF OF PATIENTS WITH PARKINSON'S DISEASEOctober 2022December 2024Allow2621YesNo
18049490Methods and Compositions for Diagnosis and Prognosis of Renal Injury and Renal FailureOctober 2022March 2024Abandon1710NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for art-unit 1678.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
47
Examiner Affirmed
40
(85.1%)
Examiner Reversed
7
(14.9%)
Reversal Percentile
0.7%
Lower than average

What This Means

With a 14.9% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
309
Allowed After Appeal Filing
68
(22.0%)
Not Allowed After Appeal Filing
241
(78.0%)
Filing Benefit Percentile
9.0%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 22.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

⚠ Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

⚠ Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Art Unit 1678 - Prosecution Statistics Summary

Executive Summary

Art Unit 1678 is part of Group 1670 in Technology Center 1600. This art unit has examined 4,226 patent applications in our dataset, with an overall allowance rate of 64.4%. Applications typically reach final disposition in approximately 36 months.

Comparative Analysis

Art Unit 1678's allowance rate of 64.4% places it in the 19% percentile among all USPTO art units. This art unit has a significantly lower allowance rate than most art units at the USPTO.

Prosecution Patterns

Applications in Art Unit 1678 receive an average of 2.08 office actions before reaching final disposition (in the 72% percentile). The median prosecution time is 36 months (in the 16% percentile).

Strategic Considerations

When prosecuting applications in this art unit, consider the following:

  • The art unit's allowance rate suggests a more challenging examination environment compared to the USPTO average.
  • With more office actions than average, plan for relatively streamlined prosecution.
  • The median prosecution time is longer than average and should be factored into your continuation and client communication strategies.
  • Review individual examiner statistics within this art unit to identify examiners with particularly favorable or challenging prosecution patterns.

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.