USPTO Examiner MIDDLETON DANAYA L - Art Unit 1674

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18592746IL-11 ANTIBODIESMarch 2024December 2024Allow921YesNo
18500622ANTI-STEM CELL FACTOR ANTIBODIES AND METHODS OF BLOCKING THE INTERACTION BETWEEN SCF AND c-KITNovember 2023May 2025Allow1810YesNo
16972460MULTI-SPECIFIC BINDING PROTEINS AND METHODS OF USE THEREOFAugust 2023December 2024Allow4811YesNo
17669398COMPLEMENT C3 ANTIGEN BINDING PROTEINSFebruary 2022January 2025Allow3521YesNo
17517236DOSING FOR TREATMENT WITH ANTI-CD20/ANTI-CD3 BISPECIFIC ANTIBODIESNovember 2021February 2025Allow4031NoNo
17453151METHODS AND COMPOSITIONS FOR TREATMENT OF LUPUSNovember 2021February 2025Allow3930YesYes
17513636GLYCOPROTEIN WITH REDUCED ACETYLATION RATE OF SIALIC ACID RESIDUESOctober 2021February 2025Abandon4001NoNo
17412139METHODS AND COMPOSITIONS RELATING TO GLP1R VARIANTSAugust 2021April 2025Allow4421YesNo
17298174Substance for Treating and/or Preventing Intolerance Diseases, and Design Method and Preparation Method thereofMay 2021June 2025Abandon4811NoNo
17298158Substance for Treating and/or Preventing Allergic Diseases, and Design Method and Preparation Method thereofMay 2021March 2025Abandon4521NoNo
17298017SUBSTANCE FOR TREATMENT OR PREVENTION OF DISEASES, METHOD FOR DESIGNING THE SAME, AND METHOD FOR PREPARING THE SAMEMay 2021April 2025Abandon4611NoNo
17328050ANTI-PD-1 ANTIBODIESMay 2021September 2023Allow2831YesNo
17269449HUMAN IL-4R BINDING ANTIBODY, ANTIGEN BINDING FRAGMENT THEREOF, AND MEDICAL USE THEREOFFebruary 2021August 2024Allow4221YesNo
17264594NOVEL TRANSCRIPTION ACTIVATORJanuary 2021January 2025Abandon4811NoNo
17263534ANTI-SIGLEC-5 ANTIBODIES AND METHODS OF USE THEREOFJanuary 2021November 2024Allow4631NoNo
17255378Anti-CD98hc VNARs for Crossing the Blood Brain Barrier and Type IV VNAR LibrariesDecember 2020October 2024Allow4621YesNo
17125533NOVEL BISPECIFIC AGONISTIC 4-1BB ANTIGEN BINDING MOLECULESDecember 2020November 2024Abandon4721NoNo
16973855Novel Immune Checkpoint InhibitorsDecember 2020March 2025Abandon5121NoNo
16952848MULTI-CHAIN CHIMERIC POLYPEPTIDES AND USES THEREOFNovember 2020May 2024Allow4231YesNo
17051272CARBOXYLATED OSTEOCALCIN FOR TREATMENT OF AMYLOIDOSIS OR DISEASES ASSOCIATED WITH ABNORMAL PROTEIN FOLDINGOctober 2020May 2025Abandon5421NoNo
17050009DOWNREGULATION OF SNCA EXPRESSION BY TARGETED EDITING OF DNA-METHYLATIONOctober 2020June 2025Abandon5521NoNo
17045829CHIMERIC NOTCH RECEPTORSOctober 2020April 2025Abandon5421NoNo
17045246RAMUCIRUMAB FOR THE TREATMENT OF CANCERS IN PEDIATRIC PATIENTSOctober 2020January 2025Abandon5141NoNo
17044970TRISPECIFIC BINDING MOLECULES AGAINST CANCERS AND USES THEREOFOctober 2020May 2025Abandon5641YesNo
17041100CD47 BINDING AGENTSSeptember 2020February 2025Allow5312YesNo
16971712CRISPR/Cas9 Systems, and Methods of Use ThereofAugust 2020March 2025Abandon5511NoNo
16970199CANCER LESION TISSUE EVALUATION FOR OPTIMIZING EFFECT OF BORON NEUTRON CAPTURE THERAPYAugust 2020October 2024Abandon5111NoNo
16967888Adhesion Receptor Constructs and Uses Thereof in Natural Killer Cell ImmunotherapyAugust 2020December 2024Abandon5211NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner MIDDLETON, DANAYA L.

Strategic Value of Filing an Appeal

Total Appeal Filings
1
Allowed After Appeal Filing
1
(100.0%)
Not Allowed After Appeal Filing
0
(0.0%)
Filing Benefit Percentile
95.5%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 100.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the top 25% across the USPTO, indicating that filing appeals is particularly effective here. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Strategic Recommendations

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner MIDDLETON, DANAYA L - Prosecution Strategy Guide

Executive Summary

Examiner MIDDLETON, DANAYA L works in Art Unit 1674 and has examined 27 patent applications in our dataset. With an allowance rate of 44.4%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 47 months.

Allowance Patterns

Examiner MIDDLETON, DANAYA L's allowance rate of 44.4% places them in the 5% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by MIDDLETON, DANAYA L receive 1.93 office actions before reaching final disposition. This places the examiner in the 62% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by MIDDLETON, DANAYA L is 47 months. This places the examiner in the 1% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +78.4% benefit to allowance rate for applications examined by MIDDLETON, DANAYA L. This interview benefit is in the 100% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 25.0% of applications are subsequently allowed. This success rate is in the 28% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 66.7% of cases where such amendments are filed. This entry rate is in the 88% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 200.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 93% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences are highly effective with this examiner compared to others. Before filing a full appeal brief, strongly consider requesting a PAC. The PAC provides an opportunity for the examiner and supervisory personnel to reconsider the rejection before the case proceeds to the PTAB.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 86% percentile among all examiners. Of these withdrawals, 100.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 57.1% are granted (fully or in part). This grant rate is in the 72% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 3% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Request pre-appeal conferences: PACs are highly effective with this examiner. Before filing a full appeal brief, request a PAC to potentially resolve issues without full PTAB review.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.