USPTO Examiner LI RUIXIANG - Art Unit 1674

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18929510METHODS FOR THE TREATMENT OF THYROID EYE DISEASEOctober 2024February 2025Allow410YesNo
18804738INTERLEUKIN 21 VARIANTSAugust 2024January 2025Allow510NoNo
18790955ANTI-GPRC5D ANTIBODIES AND COMPOSITIONSJuly 2024December 2024Allow401NoNo
18671801TREATMENT OF INFLAMMATORY CONDITIONS BY DELIVERY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST FUSION PROTEINMay 2024October 2024Allow510NoNo
18656092ANTI-SLC34A2 MONOCLONAL ANTIBODIES AND USES THEREOFMay 2024September 2024Allow501NoNo
18656236IL23R BINDING MOLECULES AND METHODS OF USEMay 2024March 2025Abandon1001NoNo
18583481ERBB-2 AND ERBB-3 BINDING BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF CELLS THAT HAVE AN NRG1 FUSION GENEFebruary 2024November 2024Allow820NoNo
18431767METHODS OF USING IMMUNOTHERAPEUTICS THAT BIND FOLATE RECEPTOR ALPHAFebruary 2024February 2025Allow1211NoNo
18426199HOMODIMERIC ANTIBODIES FOR USE IN TREATING CANCERS AND METHODS OF USEJanuary 2024January 2025Allow1211NoNo
18402604COMPOSITIONS AND METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHYJanuary 2024August 2024Allow720NoNo
18556606ANTI-CLDN4/ANTI-CD137 BISPECIFIC ANTIBODYOctober 2023October 2024Allow1211NoNo
18555338HYPERIMMUNIZED EGG PRODUCT FOR TREATING OR PREVENTING ALCOHOLIC LIVER DISEASE AND GRAFT-VERSUS-HOST DISEASEOctober 2023May 2025Allow1921NoNo
18331422PHARMACEUTICAL COMPOSITION COMPRISING ANTI-HUMAN TSLP RECEPTOR ANTIBODYJune 2023June 2025Allow2510NoNo
18327091TRANSFERRIN BINDING ANTIBODIES AND USE THEREOFJune 2023July 2024Allow1311YesNo
18193030Artificial Cell Death Polypeptide For Chimeric Antigen Receptor And Uses ThereofMarch 2023August 2024Allow1622NoNo
18189065ANTI-FLT-1 ANTIBODIES FOR TREATING DUCHENNE MUSCULAR DYSTROPHYMarch 2023June 2025Allow2611NoNo
18068237Anti-MARCO Antibodies and Uses ThereofDecember 2022April 2025Allow2710NoNo
18058239THERAPEUTIC ANTIBODIES AGAINST ROR-1 PROTEIN AND METHODS FOR USE OF SAMENovember 2022September 2024Allow2200NoNo
18047988CHIMERIC ANTIGEN RECEPTORS AGAINST MULTIPLE HLA-G ISOFORMSOctober 2022January 2025Allow2710NoNo
18046082COMPOSITIONS FOR INCREASING HALF-LIFE OF A THERAPEUTIC AGENT IN FELINES AND METHODS OF USEOctober 2022February 2025Allow2811NoNo
17933709TARGETING CELL TROPISM RECEPTORS TO INHIBIT CYTOMEGALOVIRUS INFECTIONSeptember 2022December 2024Allow2610NoNo
17942695TGF-BETA SUPERFAMILY TYPE I AND TYPE II RECEPTOR HETEROMULTIMERS AND USES THEREOFSeptember 2022May 2025Allow3220NoNo
17929572TREATMENT OF INFLAMMATORY CONDITIONS BY DELIVERY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST FUSION PROTEINSeptember 2022March 2025Abandon3010NoNo
17819161ANTI-IL-22R ANTIBODIESAugust 2022March 2025Abandon3110NoNo
17817295COMBINATION THERAPIES AND PATIENT STRATIFICATION WITH BISPECIFIC ANTI-EGFR/C-MET ANTIBODIESAugust 2022September 2024Allow2600NoNo
17814434COMPOSITIONS AND METHODS FOR TREATING CEACAM POSITIVE CANCERSJuly 2022March 2025Allow3211NoNo
17812256ANTI-GITR ANTIBODIES AND USES THEREOFJuly 2022March 2025Abandon3201NoNo
17847380TARGETED MODIFIED TNF FAMILY MEMBERSJune 2022October 2024Allow2810NoNo
17846845APPARATUS AND METHOD FOR OOCYTE RESCUE IN VITRO POST STIMULATIONJune 2022February 2024Abandon1911NoNo
17808248ANTI-GITR ANTIBODIES AND METHODS OF USE THEREOFJune 2022November 2024Abandon2801NoNo
17831254DIAGNOSTIC ASSAYS AND KITS FOR DETECTION OF FOLATE RECEPTOR 1June 2022March 2025Abandon3311NoNo
17752074METHOD FOR THE PRODUCTION OF A GLYCOSYLATED IMMUNOGLOBULINMay 2022March 2025Abandon3401NoNo
17747764GPCR BINDING PROTEINS AND SYNTHESIS THEREOFMay 2022March 2025Abandon3411NoNo
17733026FUSOKINES INVOLVING CYTOKINES WITH STRONGLY REDUCED RECEPTOR BINDING AFFINITIESApril 2022May 2025Allow3621NoNo
17687934VARIANT ACTRIIB PROTEINS AND USES THEREOFMarch 2022October 2024Allow3111NoNo
17666705ALK4:ACTRIIB HETEROMULTIMERS AND USES THEREOFFebruary 2022November 2024Allow3320NoNo
17632107RELAXIN ANALOGS AND METHODS OF USING THE SAMEFebruary 2022January 2025Allow3611NoNo
17579345ADAMTS Binding ImmunoglobulinsJanuary 2022September 2024Allow3220NoNo
17561448AGONISTIC ANTI-TUMOR NECROSIS FACTOR RECEPTOR 2 ANTIBODIESDecember 2021December 2024Allow3511NoNo
17561496COMPOSITIONS AND METHODS FOR TARGETING ACTIVIN SIGNALING TO TREAT CANCERDecember 2021January 2025Allow3711YesNo
17531365METHODS FOR THE TREATMENT OF THYROID EYE DISEASENovember 2021September 2024Allow3420NoNo
17531368METHODS FOR THE TREATMENT OF THYROID EYE DISEASENovember 2021November 2024Allow3611NoNo
17524883THERAPIES WITH LANTHIONINE C-LIKE PROTEIN 2 LIGANDS AND CELLS PREPARED THEREWITHNovember 2021July 2024Allow3210NoNo
17523226SINGLE-ARM TYPE I AND TYPE II RECEPTOR FUSION PROTEINS AND USES THEREOFNovember 2021November 2024Allow3621NoNo
17522600MONOCLONAL ANTI-IL-1RACP ANTIBODIESNovember 2021October 2024Allow3511NoNo
17517370Senescent Cell BiomarkersNovember 2021January 2025Allow3921YesNo
17474718IL1-R1 DERIVED INHIBITOR OF IL-1b AND USE THEREOFSeptember 2021January 2024Abandon2801NoNo
17398294Bispecific EGFR/C-Met AntibodiesAugust 2021November 2023Abandon2730NoNo
17358788METHODS AND COMPOSITIONS FOR INHIBITION OF EGF/EGFR PATHWAY IN COMBINATION WITH TYROSINE KINASE INHIBITORSJune 2021December 2024Allow4131YesNo
17303970EXPRESSION OF NOVEL CELL TAGSJune 2021August 2024Allow3831YesNo
17282249CHIMERIC ANTIGEN WITH ENHANCED MULTI-IMMUNE FUNCTION THROUGH SPECIFIC BINDING TO TARGET CELL, AND USE THEREOFApril 2021June 2025Abandon5011NoNo
17198229ANTIBODIES TO GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR AND USES THEREOFMarch 2021February 2025Allow4721NoNo
17256547Vaccine Composition for Preventing or Treating Diseases Caused by Severe Fever with Thrombocytopenia Syndrome (SFTS) Viral InfectionDecember 2020May 2025Abandon5311NoNo
17254762HEPATITIS B AND/OR HEPATITIS D-PERMISSIVE CELLS AND ANIMALSDecember 2020March 2025Abandon5111NoNo
17253811TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITORDecember 2020March 2025Abandon5111NoNo
17059583NOVEL INTERLEUKIN-2 AND USE THEREOFNovember 2020December 2024Allow4811NoNo
17058130Endogenous Labelling of Extracellular VesiclesNovember 2020January 2025Abandon5001NoNo
17056632TREATMENT OF CIDPNovember 2020February 2025Allow5120NoNo
17053230EPITOPE RESTRICTION FOR ANTIBODY SELECTIONNovember 2020January 2025Allow5021YesNo
17052783NOVEL BINDERS OF TGFBeta-SUPERFAMILY LIGANDS AND USES THEREOFNovember 2020July 2024Allow4421YesNo
16977265METHODS AND COMPOSITIONS FOR TREATING NATALIZUMAB-ASSOCIATED PROGRESSIVE MULTIFOCAL ENCEPHALOPATHYSeptember 2020November 2024Abandon5011NoNo
16976983TECHNIQUES FOR GENERATING CELL-BASED THERAPEUTICS USING RECOMBINANT T CELL RECEPTOR GENESAugust 2020August 2024Allow4811NoNo
16855883COMPOSITIONS AND METHODS USEFUL IN PROMOTING MILK PRODUCTIONApril 2020July 2024Allow5121NoYes
16627266COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCERDecember 2019May 2024Allow5341NoNo
16534230METHODS AND COMPOSITIONS FOR INHIBITION OF EGF/EGFR PATHWAY IN COMBINATION WITH ANAPLASTIC LYMPHOMA KINASE INHIBITORSAugust 2019November 2024Allow6071NoNo
16218287SOLUBLE MEDIATORDecember 2018May 2019Allow510NoNo
16015988COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF INFLAMMATORY BOWEL DISEASEJune 2018June 2019Allow1211NoNo
15983688ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOFMay 2018November 2018Allow600NoNo
15975591Soluble MediatorMay 2018February 2019Allow910NoNo
15958977NSP4 INHIBITORS AND METHODS OF USEApril 2018November 2018Allow700NoNo
15943137FGFR3 Binding MoleculesApril 2018March 2020Allow2411NoNo
15704917DIAGNOSTIC AND SCREENING METHODS FOR ATOPIC DERMATITISSeptember 2017October 2018Allow1411NoNo
15453451GITR Antibodies, Methods, and UsesMarch 2017June 2019Allow2711NoNo
15506266METHODS FOR IDENTIFYING A RECEPTOR FOR A LIGAND AND USES THEREOFFebruary 2017June 2019Allow2821YesNo
15328997MEMORY INVARIANT NKT CELL MARKERJanuary 2017April 2019Allow2711NoNo
15387095DOSAGE AND ADMINISTRATION OF ANTI-EGFR THERAPEUTICSDecember 2016October 2017Allow1010NoNo
15221832CANCER TARGETING BY ANTI-EGFR PEPTIDES AND APPLICATIONS THEREOFJuly 2016May 2019Allow3421NoNo
15094843NSP4 INHIBITORS AND METHODS OF USEApril 2016February 2018Allow2311NoNo
14811967TFEB VARIANTS AND USES THEREOFJuly 2015August 2015Allow100NoNo
14642776LRRC8 PROTEINS AND PROTEIN COMPLEXES AND METHODS FOR IDENTIFICATION OF CHANNEL MODULATORSMarch 2015November 2017Allow3211NoNo
14418684HISTOLOGICAL MARKERS FOR IDENTIFYING NON-SMALL CELL LUNG CARCINOMA PATIENTS FOR TREATMENT WITH AN ENTI-EGFR DRUGJanuary 2015November 2017Allow3331YesNo
14535853GLUCAGON/GLP-1 RECEPTOR CO-AGONISTSNovember 2014May 2016Allow1811NoNo
14375334CELL BASED SENSOROctober 2014March 2017Allow3211NoNo
14513716COMBINATION THERAPY FOR BREAST CANCEROctober 2014March 2015Allow501NoNo
14500000DIAGNOSTIC AND SCREENING METHODS FOR ATOPIC DERMATITISSeptember 2014June 2017Allow3321YesYes
14312191METHOD FOR ASSESSMENT OF POTENTIAL FOR DEVELOPMENT OF DRAVET SYNDROME AND USE THEREOFJune 2014October 2014Allow301NoNo
14305263RENAL CELL CARCINOMA BIOMARKERSJune 2014May 2015Allow1121NoNo
14364888ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOFJune 2014February 2018Allow4431NoNo
14363346METHODS OF IDENTIFYING AND USING MDM2 INHIBITORSJune 2014November 2017Allow6041YesNo
14178384USE OF LXR ANTAGONISTS FOR TREATMENT OF SIDE EFFECTS OF ELEVATED GLUCOCORTICOID LEVELSFebruary 2014May 2016Allow2721YesNo
14235274NOVEL ANTI-CXCR4 ANTIBODY AND ITS USE FOR THE DETECTION AND DIAGNOSIS OF CANCERJanuary 2014August 2016Allow3021NoNo
14163158Kv1.3 Antagonists and Methods of UseJanuary 2014January 2018Allow4851NoYes
14007683Inhibitors of Metastasis, Methods of Generating Such Inhibitors and Their Therapeutic ApplicationsJanuary 2014May 2017Allow4441NoNo
14007932Compositions And Methods For Treating, Diagnosing And Monitoring DiseaseJanuary 2014June 2017Allow4541YesNo
14116186ANTIBODIES AGAINST TROPOMYOSIN-RELATED KINASE B RECEPTORSDecember 2013March 2015Allow1620YesNo
14003505TFEB VARIANTS AND USES THEREOFOctober 2013April 2015Allow2011NoNo
13947603ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR ANTIBODIES FOR DIAGNOSTIC AND CLINICAL APPLICATIONSJuly 2013November 2014Allow1621NoNo
13933789ANTI SYSTEM ASC AMINO ACID TRANSPORTER 2 (ASCT2) ANTIBODYJuly 2013October 2013Allow400NoNo
13997489BIOASSAY METHOD FOR DETECTING PHYSIOLOGICALLY ACTIVE SUBSTANCEJune 2013December 2015Allow2921YesNo
13888716ANTI-VEGFR-3 ANTIBODY COMPOSITIONSMay 2013April 2014Allow1121NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner LI, RUIXIANG.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
3
Examiner Affirmed
1
(33.3%)
Examiner Reversed
2
(66.7%)
Reversal Percentile
85.5%
Higher than average

What This Means

With a 66.7% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
34
Allowed After Appeal Filing
16
(47.1%)
Not Allowed After Appeal Filing
18
(52.9%)
Filing Benefit Percentile
73.8%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 47.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner LI, RUIXIANG - Prosecution Strategy Guide

Executive Summary

Examiner LI, RUIXIANG works in Art Unit 1674 and has examined 253 patent applications in our dataset. With an allowance rate of 93.7%, this examiner allows applications at a higher rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 32 months.

Allowance Patterns

Examiner LI, RUIXIANG's allowance rate of 93.7% places them in the 81% percentile among all USPTO examiners. This examiner is more likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by LI, RUIXIANG receive 1.96 office actions before reaching final disposition. This places the examiner in the 63% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by LI, RUIXIANG is 32 months. This places the examiner in the 30% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +8.4% benefit to allowance rate for applications examined by LI, RUIXIANG. This interview benefit is in the 41% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 31.8% of applications are subsequently allowed. This success rate is in the 58% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 59.3% of cases where such amendments are filed. This entry rate is in the 82% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 91.7% of appeals filed. This is in the 82% percentile among all examiners. Of these withdrawals, 63.6% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 62.3% are granted (fully or in part). This grant rate is in the 79% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 37.5% of allowed cases (in the 100% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.8% of allowed cases (in the 54% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.