USPTO Examiner LEE JIA HAI - Art Unit 1658

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18783556METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1July 2024October 2025Abandon1520NoYes
18783777METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1July 2024September 2025Abandon1421NoNo
18422878COMPOSITIONS OF PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTORJanuary 2024June 2025Allow1711NoNo
18507435MACROMOLECULESNovember 2023February 2026Abandon2711NoNo
18386971PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASESNovember 2023June 2025Abandon1911NoNo
18366130TREATMENT OF PEDIATRIC TYPE 2 DIABETES MELLITUS PATIENTSAugust 2023March 2025Abandon1911NoNo
18338970ULINASTATIN POLYPEPTIDESJune 2023March 2026Allow3310YesNo
18328029METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONSJune 2023November 2025Abandon2911NoNo
18203411HEMOSTATIC COMPOSITIONSMay 2023March 2025Abandon2211NoNo
18195078COMPOSITIONS FROM GASTROINTESTINAL TRACT MUCINS, AND USES THEREOFMay 2023October 2024Abandon1721NoNo
18309359MINIMALLY TOXIC PRODRUGSApril 2023December 2024Abandon1901NoNo
18167010TREATMENT OF FRAGILE X SYNDROMEFebruary 2023October 2024Abandon2010NoNo
18165695THERAPEUTIC MOLECULESFebruary 2023April 2025Abandon2611NoNo
18081969ZINC-CHARGED PEPTIDES FOR THE TREATMENT OF CANCER AND ALZHEIMER'S DISEASEDecember 2022April 2024Allow1621YesNo
18057898PEPTIDES DERIVED FROM FIBRONECTIN WITH IMPROVED BIOACTIVITY AND REDUCED SUSCEPTIBILITY TO NEUTROPHIL ELASTASE DEGRADATIONNovember 2022September 2024Abandon2201NoNo
17986922ZWITTERIONIC POLYPEPTIDE AND DERIVATIVE THEREOF AND NANODRUG BASED THEREONNovember 2022September 2025Abandon3421NoNo
17979531LONG-ACTING CONJUGATES OF GLP-2 DERIVATIVESNovember 2022February 2026Abandon3931YesNo
17976603METHODS AND COMPOSITIONS FOR IMPROVING KIDNEY FUNCTION IN PATIENTS WITH HEPATORENAL SYNDROMEOctober 2022February 2026Abandon3931YesYes
17972348CLEAVABLE LINKER COMPOSITIONS AND METHODSOctober 2022September 2024Abandon2311YesNo
17799552POLYPEPTIDE DRUG FOR PREVENTING AND/OR TREATING NEUROBLASTOMA AND USE THEREOFAugust 2022March 2024Abandon1920NoNo
17814363CATIONIC CELL PENETRATING PEPTIDES AND THE USE THEREOFJuly 2022September 2023Allow1412YesNo
17869348DRUG FOR INHIBITING ADIPOSE CELL DIFFERENTIATION AND INSULIN RESISTANCEJuly 2022September 2025Abandon3851NoNo
17811302OLIGOPEPTIDE WITH ANTI-INFLAMMATORY ACTIVITY, PREPARATION METHOD, AND APPLICATION THEREOFJuly 2022April 2023Allow910NoNo
17855002METHODS FOR INCREASING INTRACELLULAR ACTIVITY OF HSP70June 2022December 2025Abandon4121NoNo
17843866ANTIMICROBIAL NCR13 VARIANT PEPTIDESJune 2022March 2023Allow911YesNo
17838028CYCLIC COMPOUNDS FOR TREATING CANCERJune 2022January 2026Allow4341NoNo
17749713TGFBR2-BASED CHIMERIC PROTEINSMay 2022October 2025Abandon4131NoNo
17749969Alpha-sheet Polypeptides and Their UseMay 2022November 2024Allow3011YesNo
17746474FGF21 COMPOUND / GLP-1R AGONIST COMBINATIONS WITH OPTIMIZED ACTIVITY RATIOMay 2022May 2024Abandon2411NoNo
17737008iRGD-ANALOGS AND RELATED THERAPEUTIC METHODSMay 2022February 2025Abandon3421NoNo
17735371ALBUMIN-BINDING PRODRUG FOR PREVENTING OR TREATING CANCER AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAMEMay 2022January 2025Abandon3341NoNo
17728582ERYTHROPOIETIN COMPOSITIONS AND METHODS OF USEApril 2022July 2024Abandon2721NoNo
17703523REDIRECTING DEATH-INDUCING SIGNAL COMPLEX (DISC) BY MODIFYING DEATH RECEPTOR AGONIST TO INDUCE CELL DEATH FOR CANCER TREATMENTMarch 2022February 2025Abandon3531NoNo
17698185BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2March 2022October 2023Allow1911YesNo
17686748PEPTIDES AND PEPTIDE CONJUGATES FOR TREATING MENTAL DISORDERSMarch 2022March 2024Abandon2421NoNo
17586807LIPOSOMES AND USES THEREOFJanuary 2022June 2023Allow1601NoNo
17631019COMPOSITIONS COMPRISING BOVINE ADRENAL MEDULLA 8-22 (BAM8-22) PEPTIDE ANALOGS AND METHODS OF USEJanuary 2022October 2025Abandon4501NoNo
17559430NEUREGULIN-4 COMPOUNDS AND METHODS OF USEDecember 2021June 2024Allow3021YesNo
17551493TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS USING PKC ACTIVATORSDecember 2021March 2025Abandon3941NoNo
17549369PEPTIDES AND USE OF SAME IN THE TREATMENT OF DISEASES, DISRODERS OR CONDITIONS ASSOCIATED WITH A MUTANT P53December 2021April 2024Abandon2811NoNo
17617709An improved process for the preparation of PlecanatideDecember 2021January 2026Allow4911YesNo
17544773ZINC-CHARGED PEPTIDES FOR THE TREATMENT OF CANCER AND ALZHEIMER'S DISEASEDecember 2021March 2023Allow1521YesNo
17543213NANOSPHERES OF SEC14-LIKE PROTEINS AND COGNATE LIGANDSDecember 2021January 2024Abandon2511NoNo
17531538COMPOSITIONS OF PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTORNovember 2021February 2023Allow1501NoNo
17526861FOOD ADDITIVE INCLUDING MANNAN OLIGOSACCHARIDES TO ENHANCE ANIMAL PERFORMANCE AND METHOD OF USING THE SAMENovember 2021May 2024Abandon3021NoNo
17506876Therapeutic moleculesOctober 2021November 2022Allow1311YesNo
17485171MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOFSeptember 2021December 2024Abandon3931YesNo
17475545METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY AND FIBROTIC PULMONARY DISORDERSSeptember 2021April 2025Abandon4311NoNo
17469491Peptide Inhibitors Targeting Methyltransfer Mechanism of SARS-CoV-2September 2021December 2025Allow5251YesNo
17436424PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAMESeptember 2021September 2025Abandon4821NoNo
17459842PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASESAugust 2021December 2023Abandon2711NoNo
17430037A MEMBRANE-BOUND FIT-1 DECOY AND USES THEREOFAugust 2021July 2025Abandon4821YesNo
17398500CLEAVABLE LINKER COMPOSITIONS AND METHODSAugust 2021July 2022Allow1111YesNo
17383675METHODS FOR PREPARING PURIFIED POLYPEPTIDE COMPOSITIONSJuly 2021June 2023Abandon2301NoNo
17350497DEUTERATED COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCERS ASSOCIATED WITH ETBR ACTIVATIONJune 2021April 2024Allow3411YesNo
17341465POLYPEPTIDES WITH PHASE TRANSITION, TRIBLOCK POLYPEPTIDES OF THE POLYPEPTIDE-CALMODULIN-POLYPEPTIDE WITH MULTI-STIMULI RESPONSIVENESS, HYDROGEL OF THE TRIBLOCK POLYPEPTIDES, AND ITS USESJune 2021November 2023Allow2911YesNo
17296679CYCLIC PEPTIDES AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDERSMay 2021September 2024Allow3911NoNo
17329225INTRANASAL ADMINISTRATIONMay 2021August 2023Abandon2611NoNo
17327863COMBINATION THERAPY INCLUDING SAPC-DOPS FOR THE TREATMENT OF PANCREATIC CANCERMay 2021September 2023Abandon2811NoNo
17296369LPL-GPIHBP1 FUSION POLYPEPTIDESMay 2021January 2025Abandon4401NoNo
17309373COMPOUND, USE, PHARMACEUTICAL COMPOSITION, METHOD OF DIAGNOSIS, METHOD OF TREATMENT, AND METHOD OF TRANSPORTATION AND/OR INTERNALIZATION OF A COMPOUND INTO EUKARYOTIC CELLSMay 2021November 2024Allow4221YesNo
17320907NANOPARTICLE COMPOSITIONS AND USES THEREOFMay 2021July 2025Abandon5131NoNo
17320760STORAGE STABLE SOMATOSTATIN-DOPAMINE CHIMERIC COMPOUNDS AND SALT FORMS THEREOFMay 2021March 2022Abandon1010NoNo
17226996THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASEApril 2021May 2025Abandon4922NoNo
17212951METHODS FOR REGULATING TRANSCRIPTION OF MULTIPLE GENES AND EXPRESSION OF MULTIPLE TARGETSMarch 2021March 2023Allow2410YesNo
17207222FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHODS OF USEMarch 2021April 2024Abandon3750NoYes
17184745HYDROGEL COMPOSITION AND ASSOCIATED METHOD OF USEFebruary 2021September 2025Abandon5551NoNo
17141876Methods and Compositions for Treating a Disease Condition in a SubjectJanuary 2021February 2025Abandon5042NoNo
17129303TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER EYE DISEASES WITH APOLIPOPROTEIN MIMETICSDecember 2020April 2023Abandon2701NoNo
17254617SUSTAINED-RELEASE DRUG DELIVERY SYSTEMS COMPRISING AN INTRAOCULAR PRESSURE LOWERING AGENT, A CNP COMPOUND, AN NPR-B COMPOUND, A TIE-2 AGONIST, OR NEUROTROPHIC AGENT FOR USE FOR TREATING GLAUCOMA OR OCULAR HYPERTENSIONDecember 2020August 2025Abandon5641NoNo
17102427SELECTIVE MCL-1 BINDING PEPTIDESNovember 2020April 2023Abandon2801NoNo
17083409METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1 AND LOW MEAN ARTERIAL PRESSUREOctober 2020January 2023Abandon2630NoNo
17047258COMPOSITIONS AND METHODS FOR THE TREATMENT OF SENESCENT TUMOR CELLSOctober 2020November 2023Abandon3721YesNo
17031583PEPTIDE PHARMACEUTICALSSeptember 2020August 2023Abandon3531NoNo
17028400TREATMENT OF PEDIATRIC TYPE 2 DIABETES MELLITUS PATIENTSSeptember 2020December 2023Abandon3921NoNo
17016168PEPTIDE INHIBITORS OF PHOSPHOGLYCERATE MUTASE AND METHODS OF USESeptember 2020September 2022Abandon2401NoNo
16970894GEL-FORMING POLYPEPTIDESAugust 2020May 2025Abandon5722NoNo
16993814FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHODS OF USEAugust 2020July 2021Abandon1110NoNo
16988398SELECTIVE DRUG DELIVERY COMPOSITIONS AND METHODS OF USEAugust 2020September 2022Abandon2501NoNo
16986706COMPOSITION AND METHOD FOR TREATING A PATIENT HAVING LIVER CIRRHOSISAugust 2020November 2022Abandon2731YesYes
16933908GDF11 VARIANTS AND USES THEREOFJuly 2020March 2023Allow3211YesNo
16961345TREATMENT OF FRAGILE X SYNDROMEJuly 2020February 2023Abandon3111NoNo
16925464MACROMOLECULESJuly 2020January 2024Abandon4221NoNo
16858505PROTECTIVE METALLOTHIONEIN ANALOG COMPOUNDS, THEIR COMPOSITIONS AND USE THEREOF IN THE TREATMENT OF PATHOGENIC DISEASESApril 2020March 2023Abandon3531NoNo
16754944COMBINATION THERAPY FOR TREATMENT OF BONE DISORDERSApril 2020September 2023Abandon4141NoNo
16838348ACTIVATABLE MEMBRANE-INTERACTING PEPTIDES AND METHODS OF USEApril 2020January 2023Allow3421YesNo
16835787NEUREGULIN-4 COMPOUNDS AND METHODS OF USEMarch 2020September 2021Allow1821NoNo
16832634LONG-ACTING CONJUGATES OF GLP-2 DERIVATIVESMarch 2020August 2022Allow2850YesNo
16828674METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1March 2020November 2022Abandon3220NoNo
16828681METHOD OF TREATING PATIENTS WITH HEPATORENAL SYNDROME TYPE 1March 2020January 2023Abandon3420NoNo
16826208IMPROVED PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCEMarch 2020February 2026Abandon6061NoYes
16817490THERAPEUTIC AGENT PREPARATIONS AND METHODS FOR DRUG DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICEMarch 2020May 2025Abandon6061YesNo
16500177MULTIBLOCK COPOLYPEPTIDES OF ELASTIN-BASED POLYPEPTIDES AND MUSSEL FOOT PROTEINS WITH STIMULI-RESPONSIVENESS AND SURFACE-ADHESIVE, METHODS OF PREPARING THEREOF AND USE THEREOFMarch 2020June 2024Allow5631YesNo
16798141PURIFICATION OF POLYPEPTIDES USING DUAL STAGE TANGENTIAL-FLOW ULTRAFILTRATIONFebruary 2020October 2022Abandon3120NoNo
16641013MODIFIED HEAT SHOCK PROTEINSFebruary 2020June 2025Abandon6031YesNo
16640468E-POLY-L-LYSINE DERIVATIVES HAVING FUNCTIONAL GROUP FOR CLICK CHEMISTRY, METHOD FOR PRODUCING THE SAME, AND USE THEREOFFebruary 2020March 2026Abandon6061YesNo
16751581FGF21 COMPOUND / GLP-1R AGONIST COMBINATIONS WITH OPTIMIZED ACTIVITY RATIOJanuary 2020June 2022Abandon2911NoNo
16751668MINIMALLY TOXIC PRODRUGSJanuary 2020May 2023Abandon3930YesNo
16632684CLUSTERIN FOR USE IN THE TREATMENT OF THROMBOTIC MICROANGIOPATHIESJanuary 2020August 2024Allow5561YesYes
16631315STABILIZED ANTI-MICROBIAL PEPTIDES FOR THE TREATMENT OF ANTIBIOTIC-RESISTANT BACTERIAL INFECTIONSJanuary 2020January 2022Allow2411NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner LEE, JIA-HAI.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
5
Examiner Affirmed
2
(40.0%)
Examiner Reversed
3
(60.0%)
Reversal Percentile
83.0%
Higher than average

What This Means

With a 60.0% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
42
Allowed After Appeal Filing
6
(14.3%)
Not Allowed After Appeal Filing
36
(85.7%)
Filing Benefit Percentile
16.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 14.3% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner LEE, JIA-HAI - Prosecution Strategy Guide

Executive Summary

Examiner LEE, JIA-HAI works in Art Unit 1658 and has examined 248 patent applications in our dataset. With an allowance rate of 44.4%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 31 months.

Allowance Patterns

Examiner LEE, JIA-HAI's allowance rate of 44.4% places them in the 9% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by LEE, JIA-HAI receive 2.48 office actions before reaching final disposition. This places the examiner in the 72% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by LEE, JIA-HAI is 31 months. This places the examiner in the 54% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +34.5% benefit to allowance rate for applications examined by LEE, JIA-HAI. This interview benefit is in the 82% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 7.7% of applications are subsequently allowed. This success rate is in the 3% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 25.6% of cases where such amendments are filed. This entry rate is in the 35% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 57.1% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 48% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 75.0% of appeals filed. This is in the 63% percentile among all examiners. Of these withdrawals, 73.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 86.3% are granted (fully or in part). This grant rate is in the 87% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 1.2% of allowed cases (in the 69% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.