USPTO Examiner ZOU NIANXIANG - Art Unit 1648

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18411284PREFUSION-STABILIZED HMPV F PROTEINSJanuary 2024April 2024Allow310YesNo
18454526LAMP ConstructsAugust 2023June 2024Allow911NoNo
18335893ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDESJune 2023March 2024Allow910YesNo
18296771PREFUSION-STABILIZED HMPV F PROTEINSApril 2023December 2023Allow810NoNo
18186064POLYOMAVIRUS NEUTRALIZING ANTIBODIESMarch 2023April 2024Allow1300NoNo
18185153METHODS FOR ASSESSING RISK OF DEVELOPING A VIRAL DISEASE USING A GENETIC TESTMarch 2023October 2023Allow710NoNo
18115066CANCER IMMUNOTHERAPY USING VIRUS PARTICLESFebruary 2023April 2024Allow1410NoNo
18108248COMPOSITIONS AND METHODS FOR ORGAN-PROTECTIVE EXPRESSION AND MODULATION OF CODING RIBONUCLEIC ACIDSFebruary 2023January 2024Allow1110YesNo
18100732MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOFJanuary 2023July 2024Abandon1810NoNo
18157534NUCLEOTIDE SEQUENCE EXPRESSING AN EXOSOME-ANCHORING PROTEIN FOR USE AS VACCINEJanuary 2023August 2024Abandon1910NoNo
18069058COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONSDecember 2022June 2024Abandon1810NoNo
18067940ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDESDecember 2022June 2024Allow1810NoNo
18001395RAPID LOW-COST DETECTION OF SARS-COV-2 USING ISOTHERMAL AMPLIFICATION AND SENSING METHODSDecember 2022September 2023Allow910NoNo
18060799RESTRICTIVE INVERTED TERMINAL REPEATS FOR VIRAL VECTORSDecember 2022November 2023Allow1100NoNo
18046817MATERIALS AND METHODS RELATING TO IMMUNOGENIC EPITOPES FROM HUMAN PAPILLOMAVIRUSOctober 2022June 2024Abandon2011NoNo
17894945FORMULATION OF A PEPTIDE VACCINEAugust 2022April 2024Allow2020NoNo
17887545Stable, Spray Dried, Immunogenic, Viral CompositionsAugust 2022July 2024Abandon2320NoNo
17817591COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONSAugust 2022December 2023Abandon1710NoNo
17875298METHODS OF PREDICTING SUSCEPTIBILITY TO INFECTIOUS DISEASE AND RELATED METHODS OF TREATMENTJuly 2022May 2024Abandon2110NoNo
17868144FREEZE DRIED VIRAL NANOPARTICLE CONSTRUCTSJuly 2022December 2023Allow1710NoNo
17812896COMPOSITIONS COMPRISING CURONS AND USES THEREOFJuly 2022April 2024Abandon2101NoNo
17812492Bispecific Molecules That Are Immunoreactive With Immune Effector Cells That Express An Activating Receptor And An Antigen Expressed By A Cell Infected By A Virus And Uses ThereofJuly 2022April 2024Abandon2120NoNo
17838662METHODS OF PREPARING ANTI-HUMAN PAPILLOMAVIRUS ANTIGEN T CELLSJune 2022October 2023Allow1610NoNo
17833133Composition Comprising PIC For Treatment Of CancerJune 2022October 2023Allow1710YesNo
17664717IMMUNOSTIMULATORY METHODMay 2022May 2023Allow1210NoNo
17719779Immunogenic Human Rhinovirus (HRV) CompositionApril 2022March 2024Abandon2410NoNo
17702231E1E2 HCV VACCINES AND METHODS OF USEMarch 2022December 2023Abandon2110NoNo
17694264ASSOCIATION BETWEEN INTEGRATION OF HIGH-RISK HPV GENOMES DETECTED BY MOLECULAR COMBING AND THE SEVERITY AND/OR CLINICAL OUTCOME OF CERVICAL LESIONSMarch 2022December 2023Abandon2110NoNo
17689908COMPOSITIONS AND METHODS FOR ORGAN-PROTECTIVE EXPRESSION AND MODULATION OF CODING RIBONUCLEIC ACIDSMarch 2022January 2023Allow1120YesNo
17687732MHC CLASS IA OPEN CONFORMERSMarch 2022September 2023Allow1810NoNo
17681342RECOMBINANT MVA OR MVADELE3L EXPRESSING HUMAN FLT3L AND USE THEREOF AS IMMUNO-THERAPEUTIC AGENTS AGAINST SOLID TUMORSFebruary 2022March 2024Allow2420NoNo
17680813CANCER IMMUNOTHERAPY USING VIRUS PARTICLESFebruary 2022April 2023Allow1301NoNo
17665285COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE MULTI-TARGETED ANTIGENSFebruary 2022June 2023Allow1610NoNo
17587953COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONSJanuary 2022August 2023Abandon1910NoNo
17581655ENGINEERED HEPATITIS B CORE POLYPEPTIDEJanuary 2022September 2023Abandon2011YesNo
17559391Desmoglein 2 (DSG2) Binding Proteins and Uses ThereforDecember 2021June 2023Allow1811NoNo
17557886IMMUNOSWITCH NANOPARTICLES FOR REPROGRAMMED T CELL RESPONSESDecember 2021January 2024Allow2520NoNo
17556816COMPOSITIONS OF INFLUENZA HEMAGGLUTININ WITH HETEROLOGOUS EPITOPES AND/OR ALTERED MATURATION CLEAVAGE SITES AND METHODS OF USE THEREOFDecember 2021August 2023Abandon2010YesNo
17550272VACCINES AGAINST GENITAL HERPES SIMPLEX INFECTIONSDecember 2021July 2023Abandon2010NoNo
17596061COMBINATION OF HEPATITIS B VIRUS (HBV) VACCINES AND SMALL MOLECULE PDL1 OR PD1 INHIBITORDecember 2021April 2024Abandon2820YesNo
17532177HPV VACCINENovember 2021April 2024Allow2930NoNo
17521196METHODS OF IDENTIFYING PATIENTS AS HAVING AN INCREASED LIKELIHOOD OF HAVING A HUMAN PAPILLOMA VIRUS (HPV)-ASSOCIATED CANCER OR RECURRENCE OF AN HPV-ASSOCIATED CANCERNovember 2021June 2023Allow1910YesNo
17514857LAMP ConstructsOctober 2021June 2023Allow2011NoNo
17514724METHODS FOR GENERATING THERAPEUTIC DELIVERY PLATFORMSOctober 2021October 2023Allow2411NoNo
17502910Polyomavirus Neutralizing AntibodiesOctober 2021December 2022Allow1400NoNo
17492238IN VITRO HBV CORE PROTEIN ASSAYOctober 2021January 2024Abandon2810NoNo
17484476ATTB CELL LINE, TRANSGENIC CELL LINES DERIVED THEREFROM, AND METHODS OF MAKING THE SAMESeptember 2021January 2024Allow2821NoNo
17472003MERS-CoV VaccineSeptember 2021June 2023Allow2110NoNo
17435687METHOD FOR SEQUENCING A DIRECT REPEATSeptember 2021August 2022Allow1120YesNo
17410453MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOFAugust 2021May 2023Abandon2010NoNo
17430474Method for Extracting Hepatitis A Virus (HAV) Antigen from Cell CultureAugust 2021June 2022Allow1010NoNo
17399821COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS THROUGH STIMULATED INNATE IMMUNITY IN COMBINATION WITH ANTIVIRAL COMPOUNDSAugust 2021May 2023Abandon2110NoNo
17396579SPATIAL SEQUENCINGAugust 2021July 2022Allow1130NoNo
17384589HPV-SPECIFIC BINDING MOLECULESJuly 2021June 2023Allow2210YesNo
17372927METHODS OF PREPARING ANTI-HUMAN PAPILLOMAVIRUS ANTIGEN T CELLSJuly 2021February 2022Allow810NoNo
17373093METHODS OF PREPARING ANTI-HUMAN PAPILLOMAVIRUS ANTIGEN T CELLSJuly 2021January 2022Allow610NoNo
17373130METHODS OF PREPARING ANTI-HUMAN PAPILLOMAVIRUS ANTIGEN T CELLSJuly 2021January 2022Allow610NoNo
17303063ULTRA-SENSITIVE, FAST, PLASMONIC-FLUOR ENHANCED ASSAY FOR SARS-COV-2 IMMUNE RESPONSEMay 2021May 2023Abandon2401NoNo
17320944Vaccines For Recurrent Respiratory Papillomatosis And Methods Of Using The SameMay 2021April 2023Allow2310NoNo
17319081NEUTRALIZING ANTIBODY TESTING AND TREATMENTMay 2021June 2023Allow2511YesNo
17240991METHODS OF PREDICTING SUSCEPTIBILITY TO INFECTIOUS DISEASE AND RELATED METHODS OF TREATMENTApril 2021April 2022Allow1121YesNo
17236561METHODS FOR GENERATING THERAPEUTIC DELIVERY PLATFORMSApril 2021September 2021Allow510NoNo
17301626IMMUNE COMPLEXApril 2021February 2023Allow2210NoNo
17275967METHOD FOR PRODUCING AN ANTITUMORAL ARENAVIRUS AS WELL AS ARENAVIRUS MUTANTSMarch 2021June 2024Allow3910NoNo
17194779NOVEL VACCINES AGAINST HPV AND HPV-RELATED DISEASESMarch 2021March 2023Allow2410NoNo
17168461GENERATING HPV ANTIGEN-SPECIFIC CELLS FROM A NAIVE T CELL POPULATIONFebruary 2021January 2024Allow3621NoNo
17156908METHODS AND COMPOSITIONS OF CHEMICALLY MODIFIED PHAGE LIBRARIESJanuary 2021March 2023Allow2611YesNo
17152149GENERATING HPV ANTIGEN-SPECIFIC CELLS FROM A NAIVE T CELL POPULATIONJanuary 2021January 2023Allow2410NoNo
17142486ANTI-HUMAN PAPILLOMAVIRUS 16 E6 T CELL RECEPTORSJanuary 2021February 2023Allow2610NoNo
17141704Vaccines For Human Papilloma Virus And Methods For Using The SameJanuary 2021May 2023Allow2810YesNo
17113570METHODS OF PREPARING ANTI-HUMAN PAPILLOMAVIRUS ANTIGEN T CELLSDecember 2020June 2021Allow610YesNo
15734715Mutant of L1 Protein of Human Papillomavirus Type 39December 2020April 2022Allow1610YesNo
15734750Mutant of L1 Protein of Human Papillomavirus Type 66December 2020May 2022Allow1710NoNo
17057153COMPOSITIONS AND METHODS FOR TREATING RSV-INFECTIONSNovember 2020October 2023Allow3500YesNo
16953109RESTRICTIVE INVERTED TERMINAL REPEATS FOR VIRAL VECTORSNovember 2020September 2022Allow2200NoNo
17099633COMPOSITIONS OF AND METHODS FOR IN VITRO VIRAL GENOME ENGINEERINGNovember 2020October 2023Allow3520YesNo
17055416COMPOSITIONS AND METHODS FOR DELIVERY OF AAVNovember 2020March 2024Abandon4010NoNo
17084841CHIMERIC VSV VIRUS COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF CANCEROctober 2020January 2024Abandon3921NoNo
16949331CANCER THERAPY WITH A PARVOVIRUS COMBINED WITH BEVACIZUMABOctober 2020March 2023Abandon2820NoNo
17074358RECOMBINANT VIRAL VECTORSOctober 2020September 2023Allow3520YesNo
17068087METHOD AND COMPOSITION FOR TREATING CANCER OR SKIN LESION USING A VACCINEOctober 2020August 2023Allow3421YesNo
17045753HETEROLOGOUS COMBINATION PRIME:BOOST THERAPY AND METHODS OF TREATMENTOctober 2020February 2023Abandon2811NoNo
17061146ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDESOctober 2020September 2022Allow2410NoNo
17060944RSV F Protein MutantsOctober 2020April 2023Abandon3120NoNo
17030737Attenuated Strains of Oncolytic Rhabdovirus and Uses Thereof in Tumor TreatmentSeptember 2020May 2023Allow3211YesNo
17020670Methods of Neoplasm Treatment Utilizing Complementary Oncolytic Viruses and CAR T-CellsSeptember 2020July 2023Abandon3411YesNo
17015955SEROLOGIC TEST FOR THERAPY CONTROL OF HPV16 POSITIVE CARCINOMASeptember 2020July 2022Allow2210YesNo
17016264TREATMENT AND PREVENTION OF PLANTAR WARTSSeptember 2020July 2023Abandon3511NoNo
16978570HEPATITIS B VACCINES AND USES OF THE SAMESeptember 2020August 2022Allow2411NoNo
17011990BROAD RANGE GENE AND GENOTYPE PAPILLOMAVIRUS TRANSCRIPTOME AS A BIOMARKER OF PAPILLOMAVIRUS-ASSOCIATED CANCER STAGESSeptember 2020August 2022Allow2310NoNo
16975602SPLIT-IMMUNOTOXINS FOR BOOSTING ONCOLYTIC VIRUS TOXICITYAugust 2020March 2024Allow4210YesNo
16996433VACCINE COMPOSITIONAugust 2020August 2022Abandon2410NoNo
16995647SYSTEMS AND METHODS FOR GENERATING IMMUNE RESPONSES IN SUBJECTS USING MICROCHANNEL DELIVERY DEVICESAugust 2020August 2021Allow1220YesNo
16988659VLP Stabilized Vaccine CompositionsAugust 2020December 2023Allow4050YesNo
16966387Compositions and Methods for Promoting Immune Responses to Human Immunodeficiency VirusJuly 2020October 2022Allow2720NoNo
16931291IMMUNOGENIC RSV POLYPEPTIDESJuly 2020June 2022Allow2311NoNo
16961238IMMUNOGENIC COMPOSITIONJuly 2020August 2022Allow2520YesNo
16921253COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONSJuly 2020June 2022Abandon2310NoNo
16921899DUCK HEPATITIS A VIRUS TYPE 3 MUTANT CH-P60-117C AND CONSTRUCTION THEREOFJuly 2020April 2021Allow910YesNo
16919356Stable, Spray Dried, Immunogenic, Viral CompositionsJuly 2020May 2022Allow2220YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner ZOU, NIANXIANG.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
7
Examiner Affirmed
4
(57.1%)
Examiner Reversed
3
(42.9%)
Reversal Percentile
64.0%
Higher than average

What This Means

With a 42.9% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
42
Allowed After Appeal Filing
7
(16.7%)
Not Allowed After Appeal Filing
35
(83.3%)
Filing Benefit Percentile
16.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 16.7% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner ZOU, NIANXIANG - Prosecution Strategy Guide

Executive Summary

Examiner ZOU, NIANXIANG works in Art Unit 1648 and has examined 643 patent applications in our dataset. With an allowance rate of 63.0%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 25 months.

Allowance Patterns

Examiner ZOU, NIANXIANG's allowance rate of 63.0% places them in the 16% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by ZOU, NIANXIANG receive 2.06 office actions before reaching final disposition. This places the examiner in the 68% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by ZOU, NIANXIANG is 25 months. This places the examiner in the 65% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +27.3% benefit to allowance rate for applications examined by ZOU, NIANXIANG. This interview benefit is in the 78% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 22.3% of applications are subsequently allowed. This success rate is in the 19% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 29.2% of cases where such amendments are filed. This entry rate is in the 33% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 100.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 68% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 68.2% of appeals filed. This is in the 48% percentile among all examiners. Of these withdrawals, 60.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 69.2% are granted (fully or in part). This grant rate is in the 86% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.3% of allowed cases (in the 54% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.5% of allowed cases (in the 61% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.