USPTO Examiner MCCOLLUM ANDREA K - Art Unit 1646

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17254098INTERLEUKIN-2 VARIANTS AND METHODS OF USES THEREOFDecember 2020April 2024Abandon3911NoNo
17123349PHARMACEUTICAL USE OF ACTININ-4 INVOLVED IN INDUCTION OF CERVICAL CANCERDecember 2020February 2024Abandon3820NoNo
17107554Combination Therapies and Uses for Treatment of Demyelinating DisordersNovember 2020April 2024Abandon4101NoNo
16950418ANTI-KLK5 ANTIBODIES AND METHODS OF USENovember 2020November 2023Allow3611NoNo
17095882USE OF ANTI-IL-36R ANTIBODIES FOR TREATMENT OF INFLAMMATORY BOWEL DISEASENovember 2020September 2023Abandon3411NoNo
17077049METHODS OF PROGNOSIS AND TREATMENTOctober 2020November 2023Allow3621YesNo
17073498FGFR1 AGONISTS AND METHODS OF USEOctober 2020June 2023Abandon3101NoNo
17068628IL-15 AND IL-15R\ALPHA SUSHI DOMAIN BASED IMMUNOCYTOKINESOctober 2020April 2023Allow3010NoNo
17066410SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOFOctober 2020December 2023Allow3811YesNo
17045148STING LEVELS AS A BIOMARKER FOR CANCER IMMUNOTHERAPYOctober 2020August 2023Allow3521YesNo
17024476METHOD FOR PREDICTING THERAPEUTIC EFFECT OF BIOLOGICAL PREPARATION ON RHEUMATOID ARTHRITISSeptember 2020May 2023Abandon3101NoNo
17024206USE OF PERIPHERAL BLOOD PRO- AND ANTI-INFLAMMATORY CYTOKINE RATIOS AS MARKERS OF IMPLANTATION PRECEDING PREGNANCYSeptember 2020July 2023Abandon3421NoNo
17018915PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND OTHER CANCERSSeptember 2020February 2023Allow2930NoNo
17003847CONJUGATES OF AN IL-2 MOIETY AND A POLYMERAugust 2020November 2023Abandon3811NoNo
17002072MULTIPLE-VARIABLE IL-2 DOSE REGIMEN FOR TREATING IMMUNE DISORDERSAugust 2020May 2023Abandon3310NoNo
16999088METHOD AND PLATFORM FOR DETECTING IMMUNOGENICITY OF TUMOR NEOANTIGENAugust 2020October 2023Allow3821YesNo
16997326METHOD FOR MONITORING DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEMAugust 2020May 2023Abandon3210NoNo
16986473METHODS OF IDENTIFYING AND USING AGENTS FOR TREATING DISEASES ASSOCIATED WITH INTESTINAL BARRIER DYSFUNCTIONAugust 2020April 2023Abandon3221NoNo
16984215Inhibitors Of Lactate Transporters For Use In The Treatment Of Inflammatory DiseasesAugust 2020January 2023Abandon2910NoNo
16931788ANTIBODY AGAINST HUMAN TGF-B LAP DEGRADATE, AND USE THEREOFJuly 2020October 2021Allow1511YesNo
16962566METHOD FOR QUANTITATIVELY DETERMINING A THERAPEUTIC TNF-ALPHA INHIBITORJuly 2020October 2023Allow3921NoNo
16926481ANTI-ACTIVIN A ANTIBODIES AND USES THEREOFJuly 2020March 2023Abandon3211NoNo
16916822ANTI-TRYPTASE ANTIBODIES, COMPOSITIONS THEREOF, AND USES THEREOFJune 2020August 2023Allow3720YesNo
16913840METHODS OF TREATING OR PREVENTING SERIOUS SYMPTOMS FROM COVID-19 INFECTIONJune 2020July 2023Allow3741YesNo
16913067TGF-BETA 3 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOFJune 2020June 2022Allow2410YesNo
16908271SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOFJune 2020February 2023Allow3211YesNo
16889066ANTI-MYOSTATIN ANTIBODIES, POLYPEPTIDES CONTAINING VARIANT FC REGIONS, AND METHODS OF USEJune 2020January 2022Allow2011YesNo
15931213KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONSMay 2020October 2022Abandon2901NoNo
16868293Immune Gene Signatures in CancerMay 2020August 2021Abandon1510NoNo
16755002ANTI-IL-33 THERAPY FOR ATOPIC DERMATITISApril 2020May 2021Abandon1301NoNo
16821593METHODS FOR DOSING AN ACTIVIN-ACTRIIA ANTAGONIST AND MONITORING OF TREATED PATIENTSMarch 2020February 2023Abandon3511NoNo
16819629Method of Treating Psoriasis in Pediatric Subjects with Anti-IL12/IL23 AntibodyMarch 2020March 2023Abandon3620NoYes
16819891MUTANT NGAL PROTEINS AND USES THEREOFMarch 2020March 2023Allow3611YesNo
16813780Humanized anti-CCR7 receptor antibodiesMarch 2020October 2021Allow1911NoNo
16645191METHODS AND KITS FOR DIAGNOSIS OF FAMILIAL MEDITERRANEAN FEVERMarch 2020April 2023Abandon3710NoNo
16809606ANTI-IL-36R ANTIBODY FORMULATIONSMarch 2020December 2022Allow3321YesNo
16807129COMBINATION IL-2 IMMUNOCONJUGATE THERAPYMarch 2020September 2022Abandon3101NoNo
16798247UNTARGETED AND TARGETED IL-10 FC-FUSION PROTEINSFebruary 2020February 2024Allow4741NoNo
16798088METHOD OF PREDICTING AND DETERMINING THERAPEUTIC EFFECT ON RHEUMATOID ARTHRITIS DUE TO BIOLOGICAL FORMULATIONFebruary 2020October 2021Abandon2001NoNo
16640378DETECTION OF INSULIN IN SALIVA AND METHODS OF USE THEREOFFebruary 2020March 2024Abandon4821NoNo
16796608METHODS FOR TREATING HAIR LOSS DISORDERSFebruary 2020October 2020Allow810YesNo
16782486Novel Treatment Method for Cockayne SyndromeFebruary 2020August 2021Allow1811YesNo
16633728TUMOR VACCINEJanuary 2020November 2022Abandon3410NoNo
16735833METHODS FOR DOSING AN ACTRIIB ANTAGONIST AND MONITORING OF TREATED PATIENTSJanuary 2020July 2021Abandon1810NoNo
16626844METHODS OF DELAYING AND PREVENTING ACUTE MYELOID LEUKEMIA RELAPSEDecember 2019May 2021Abandon1710NoNo
16722133ANTI-IL-36R ANTIBODIES FOR TREATMENT OF PALMOPLANTAR PUSTULOSISDecember 2019November 2022Abandon3521NoNo
16712800Method of Treating Cancer with a Cancer Therapy in Combination with Another Therapeutic AgentDecember 2019April 2024Allow5231NoNo
16712167TELOMERASE POLYPEPTIDE VACCINE FOR TREATING CANCERDecember 2019January 2024Allow5051NoNo
16709810PHARMACEUTICAL PREPARATION COMPRISING RECOMBINANT HCGDecember 2019November 2021Allow2411YesNo
16704830Methods for Producing Enteroendocrine Cells That Make and Secrete InsulinDecember 2019November 2021Abandon2311NoNo
16619140Immunoassay for Human ErythroferroneDecember 2019October 2021Allow2311YesNo
16692574COMPOSITION AND METHODS FOR DETECTING CANCERNovember 2019September 2023Allow4521NoNo
16614570DIAGNOSTICS OF GINGIVITIS BASED ON SALIVARY IL-1BETA AND HGFNovember 2019January 2024Abandon5021NoNo
16614454MIC-1 COMPOUNDS AND USES THEREOFNovember 2019March 2023Abandon4011NoNo
16686373METHOD OF TREATING PUSTULAR PSORIASIS WITH ANTIBODIES DIRECTED AGAINST INTERLEUKIN 36 RECEPTOR (IL-36R)November 2019May 2021Allow1811NoNo
16613968BIOMARKERS AND METHODS FOR DETECTION OF SEIZURES AND EPILEPSYNovember 2019September 2023Allow4621YesNo
16683124METHODS FOR USE OF PROINSULIN TRANSFERRIN FUSION PROTEINS AS PRODRUGSNovember 2019December 2022Abandon3720NoNo
16660038METHOD FOR REDUCING FLU-LIKE SYMPTOMS ASSOCIATED WITH INTRAMUSCULAR ADMINISTRATION OF INTERFERON USING A FAST TITRATION ESCALATING DOSING REGIMENOctober 2019March 2023Abandon4110NoNo
16605356IL4/IL13 Receptor Molecule for Veterinary UseOctober 2019December 2023Allow5041NoNo
16500429Cytokine CombinationOctober 2019August 2022Allow3421YesNo
16500194BIOLOGIC FOR THE TREATMENT OF CANCEROctober 2019February 2024Allow5231YesNo
16499780SYSTEMS AND METHODS FOR MANUFACTURING BIOLOGICALLY-PRODUCED PRODUCTSSeptember 2019April 2022Abandon3011NoNo
16586698COMPOSITIONS AND METHODS USEFUL FOR STABILIZING PROTEIN-CONTAINING FORMULATIONSSeptember 2019March 2022Abandon2920NoNo
16496397FUSION PROTEIN, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN PREPARING OPHTHALMIC DISEASE TREATMENT,ANTI-INFLAMMATION AND ANTI-TUMOR MEDICAMENTSeptember 2019October 2022Allow3721YesNo
16492666IL-37 FUSION PROTEIN AND METHODS OF MAKING AND USING SAMESeptember 2019July 2022Allow3421YesNo
16492555SYNTHEKINE COMPOSITIONS AND METHODS OF USESeptember 2019February 2024Abandon5321NoNo
16544421ANTI-TRYPTASE ANTIBODIES, COMPOSITIONS THEREOF, AND USES THEREOFAugust 2019April 2020Allow810NoNo
16544648ANTI-ANGIOGENESIS FUSION PROTEIN AND USES THEREOFAugust 2019August 2022Allow3521YesNo
16482778Methods and Compositions for Diagnosis and Prognosis of Renal Injury and Renal FailureAugust 2019March 2024Abandon5521NoNo
16482869TGFBETA AND ACTRII ANTAGONISTS FOR USE IN INCREASING IMMUNE ACTIVITYAugust 2019February 2024Abandon5431NoNo
16512886ANTI-IL36R ANTIBODIESJuly 2019October 2021Allow2711YesNo
16478108SYSTEMS AND METHODS FOR PRODUCTION OF RECOMBINANT IL-11 IN YEASTJuly 2019January 2023Allow4220YesNo
16512271Biomarkers for Systemic Lupus Erythematosus Disease Activity, and Intensity and FlareJuly 2019September 2022Allow3821YesNo
16509161PREVENTIVE OR THERAPEUTIC AGENT FOR KIDNEY DISEASEJuly 2019November 2021Allow2931NoNo
16476380PREFERRED PAIRING OF ANTIBODY DOMAINSJuly 2019May 2024Abandon5841YesNo
16473245ANTI-PCSK9 ANTIBODY AND USE THEREOFJune 2019June 2022Allow3611YesNo
16471756MYOSTATIN, ACTIVIN OR ACTIVIN RECEPTOR ANTAGONISTS FOR USE IN TREATING OBESITY AND RELATED CONDITIONSJune 2019May 2021Abandon2310NoNo
16471509IMMUNOCYTOKINES WITH PROGRESSIVE ACTIVATION MECHANISMJune 2019March 2021Abandon2101NoNo
16471431ANTIBODIES TO IL-37June 2019September 2021Abandon2701NoNo
16469173COMBINATION OF ANT-CD303 AND ANTI-AMHRII ANTIBODIESJune 2019January 2022Abandon3111NoNo
16466566POLYMERIC NANOPARTICLES PROVIDING NUCLEIC ACIDS ENCODING TNF-aJune 2019October 2021Allow2821YesNo
16466110TREATMENT OF OBESITY AND EATING DISORDERSJune 2019August 2024Abandon6051NoNo
16501750Lateral flow immunoassay (LFIA) system for measuring reombinant bovine somatotrophin (rBST) in whole milk and other dairy productsJune 2019October 2023Abandon5220YesNo
16424693RECOMBINANT CHICKEN INTERLEUKIN-1 BETA PROTEIN FOR PRODUCING ANTIBODY EARLY AND RETAINING FOR A LONGER PERIOD OF TIME AND APPLICATION THEREOFMay 2019February 2021Abandon2101NoNo
16422256TUMOR NECROSIS FACTOR-LIKE LIGAND 1A SPECIFIC ANTIBODIES AND COMPOSITIONS AND USES THEREOFMay 2019April 2022Allow3511YesNo
16422212Methods For Treating Chronic Obstructive Pulmonary Disease Using BenralizumabMay 2019September 2022Abandon4030NoNo
16415231Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 AntibodyMay 2019September 2021Allow2811YesNo
16461747ENGINEERED TGF-BETA MONOMERS AND THEIR USE FOR INHIBITING TGF-BETA SIGNALINGMay 2019April 2021Allow2310YesNo
16414601FGFR1 AGONISTS AND METHODS OF USEMay 2019February 2021Abandon2101NoNo
16412543IL-17 ANTAGONISTIC ANTIBODIESMay 2019August 2022Abandon3921NoYes
16393615SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOFApril 2019February 2021Allow2110YesNo
16393619SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOFApril 2019February 2021Abandon2210NoNo
16342176ANTI-IL1-RAP ANTIBODIESApril 2019February 2022Allow3421YesNo
16342275ANTI-EDB ANTIBODIES AND ANTIBODY-DRUG CONJUGATESApril 2019October 2023Abandon5431NoNo
16342462ASSAY FOR C5B-9 DEPOSITION IN COMPLEMENT-ASSOCIATED DISORDERSApril 2019August 2023Abandon5230YesNo
16341034SINGLE-DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST CTLA-4April 2019July 2022Allow3921YesNo
16334767Novel Anti-PCSK9 AntibodiesMarch 2019April 2021Allow2511YesNo
16352619ANTI-KLK5 ANTIBODIES AND METHODS OF USEMarch 2019January 2021Abandon2201NoNo
16299382METHODS FOR TREATING HAIR LOSS DISORDERSMarch 2019November 2021Allow3321NoNo
16296582USE OF ANTI-IL-36R ANTIBODIES FOR TREATMENT OF INFLAMMATORY BOWEL DISEASEMarch 2019December 2020Abandon2110NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner MCCOLLUM, ANDREA K.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
3
Examiner Affirmed
2
(66.7%)
Examiner Reversed
1
(33.3%)
Reversal Percentile
50.2%
Higher than average

What This Means

With a 33.3% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
27
Allowed After Appeal Filing
5
(18.5%)
Not Allowed After Appeal Filing
22
(81.5%)
Filing Benefit Percentile
23.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 18.5% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner MCCOLLUM, ANDREA K - Prosecution Strategy Guide

Executive Summary

Examiner MCCOLLUM, ANDREA K works in Art Unit 1646 and has examined 524 patent applications in our dataset. With an allowance rate of 50.6%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 30 months.

Allowance Patterns

Examiner MCCOLLUM, ANDREA K's allowance rate of 50.6% places them in the 14% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by MCCOLLUM, ANDREA K receive 1.83 office actions before reaching final disposition. This places the examiner in the 39% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by MCCOLLUM, ANDREA K is 30 months. This places the examiner in the 58% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +47.4% benefit to allowance rate for applications examined by MCCOLLUM, ANDREA K. This interview benefit is in the 91% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 27.2% of applications are subsequently allowed. This success rate is in the 49% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 47.8% of cases where such amendments are filed. This entry rate is in the 73% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 80.0% of appeals filed. This is in the 71% percentile among all examiners. Of these withdrawals, 75.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 71.1% are granted (fully or in part). This grant rate is in the 77% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.6% of allowed cases (in the 61% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 3.8% of allowed cases (in the 79% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.