USPTO Examiner HARTNETT BRIAN - Art Unit 1644

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18999710ANTI-FUNGAL VHH ANTIBODIESDecember 2024May 2025Allow410NoNo
18667995CHIMERIC ANTIGEN RECEPTOR AND CAR-T CELLS THAT BIND BCMAMay 2024March 2025Allow1000NoNo
18508938CONDITIONALLY ACTIVE ANTI-EPCAM ANTIBODIES, ANTIBODY FRAGMENTS, THEIR IMMUNOCONJUGATES AND USES THEREOFNovember 2023June 2025Allow1910NoNo
18508501PD1 BINDING AGENTSNovember 2023February 2025Abandon1510YesNo
18497745METHODS OF ADMINISTERING CHIMERIC ANTIGEN RECEPTOR IMMUNOTHERAPYOctober 2023May 2025Allow1810NoNo
18485680CD3-DELTA/EPSILON HETERODIMER SPECIFIC ANTIBODIESOctober 2023April 2025Abandon1810NoNo
18480825HIGHLY CONCENTRATED LOW VISCOSITY MASP-2 INHIBITORY ANTIBODY FORMULATIONS, KITS, AND METHODS OF TREATING SUBJECTS SUFFERING FROM ATYPICAL HEMOLYTIC SYNDROMEOctober 2023December 2024Abandon1510NoNo
18340600T CELL RECEPTORS THAT BIND TO MIXED LINEAGE LEUKEMIA (MLL)-SPECIFIC PHOSPHOPEPTIDES AND METHODS OF USE THEREOFJune 2023April 2025Allow2210NoNo
18333753COMPOSITIONS AND METHODS FOR IMMUNOTHERAPYJune 2023November 2024Allow1701YesNo
18333096HLA-DR CAR-T COMPOSITIONS AND METHODS OF MAKING AND USING THE SAMEJune 2023May 2025Abandon2310NoNo
18190954T CELL RECEPTORS THAT BIND TO NY-ESO-1 AND METHODS OF USE THEREOFMarch 2023November 2024Abandon1910NoNo
18188318T CELL-ANTIGEN COUPLER WITH Y182T MUTATION AND METHODS OF USES THEREOFMarch 2023December 2023Allow910NoNo
18111179ANTI-PAD2 ANTIBODY FOR TREATING AND EVALUATING AUTOIMMUNE AND INFLAMMATORY DISEASESFebruary 2023March 2025Allow2521NoNo
18020303ENRICHMENT OF T CELLS USING AN ANTI-C� ANTIBODYFebruary 2023August 2024Allow1801NoNo
18005827ANTI-HUMAN MSLN ANTIBODY AND MSLN-TARGETING IMMUNE EFFECTOR CELLJanuary 2023December 2023Allow1120NoNo
18153522ANTI-FC EPSILON-R1 ALPHA (FCER1A) ANTIBODIES, BISPECIFIC ANTIGEN-BINDING MOLECULES THAT BIND FCER1A AND CD3, AND USES THEREOFJanuary 2023June 2025Allow3011NoNo
18062084MESOTHELIN-TARGETTING ANTIBODIES, CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOFDecember 2022October 2023Allow1011YesNo
17929573METHODS FOR DELAYING ONSET OF TYPE 1 DIABETESSeptember 2022May 2025Abandon3351NoNo
17823223RECEPTORS PROVIDING TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPYAugust 2022August 2024Allow2431NoNo
17820805ANTI-TCR ANTIBODY MOLECULES AND USES THEREOFAugust 2022January 2025Allow2922NoNo
17854904ANTIBODIES THAT BIND TO OX40 AND THEIR USESJune 2022December 2024Allow3010NoNo
17807109RECEPTORS PROVIDING TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPYJune 2022July 2023Allow1311NoNo
17784988ANTI-CD19 ANTIBODIES AND MULTI-SPECIFIC BINDING PROTEINSJune 2022July 2025Allow3700NoNo
17829778HETERODIMERIC PROTEINS FOR MODULATING GAMMA DELTA T CELLSJune 2022November 2022Allow511NoNo
17663148LILRB1-BASED CHIMERIC ANTIGEN RECEPTORMay 2022May 2024Allow2431YesNo
17718372AGENTS WHICH INHIBIT GADS DIMERIZATION AND METHODS OF USE THEREOFApril 2022July 2024Abandon2701NoNo
17716737CANCER IMMUNOTHERAPYApril 2022January 2024Abandon2230YesNo
17589088LILRB1-BASED CHIMERIC ANTIGEN RECEPTORJanuary 2022August 2024Allow3010YesNo
17589093LILRB1-BASED CHIMERIC ANTIGEN RECEPTORJanuary 2022August 2024Allow3010YesNo
17588703NYESO TCRJanuary 2022May 2024Allow2810NoNo
17554180CD8 BINDING AGENTSDecember 2021March 2025Allow3910NoNo
17645004GENETICALLY MODIFIED NATURAL KILLER CELLSDecember 2021June 2025Abandon4221NoNo
17616113CONDITIONALLY ACTIVE ANTI-EPCAM ANTIBODIES, ANTIBODY FRAGMENTS, THEIR IMMUNOCONJUGATES AND USES THEREOFDecember 2021August 2023Allow2121NoNo
17496750Reagents and methods for cancer treatment using Magnetic particleOctober 2021May 2025Abandon4321NoNo
17466968BAFF-R TARGETED CHIMERIC ANTIGEN RECEPTOR-MODIFIED T-CELLS AND USES THEREOFSeptember 2021November 2024Allow3820YesNo
17462987CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORSAugust 2021June 2024Abandon3301NoNo
17404282ENGINEERED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOFAugust 2021January 2023Abandon1721YesNo
17378110HETERODIMERIC PROTEINS FOR MODULATING GAMMA DELTA T CELLSJuly 2021September 2024Allow3811NoNo
17357780T CELL RECEPTORJune 2021April 2025Allow4521YesNo
17353054CHIMERIC ANTIGEN RECEPTOR (CAR) THAT TARGETS CHEMOKINE RECEPTOR CCR4 AND ITS USEJune 2021February 2024Allow3110NoNo
17323993TIL EXPANSION FROM FINE NEEDLE ASPIRATES AND SMALL BIOPSIESMay 2021December 2023Abandon3130NoYes
17288104FUNCTIONALIZED NANOPARTICLE FORMULATIONS FOR ORAL DRUG DELIVERYApril 2021September 2024Abandon4001NoNo
17301884T CELL-ANTIGEN COUPLER WITH Y177 MUTATION AND METHODS OF USES THEREOFApril 2021October 2021Allow611YesNo
17285774LATERAL FLOW ASSAYS FOR DIFFERENTIAL ISOTYPE DETECTIONApril 2021January 2025Abandon4511NoNo
17230637LILRB1-BASED CHIMERIC ANTIGEN RECEPTORApril 2021December 2021Allow811YesNo
17276777CONDITIONALLY ACTIVE RECEPTORSMarch 2021December 2024Abandon4501NoNo
17188011CHIMERIC ANTIGEN RECEPTOR THAT BINDS HLA-DR AND CAR-T CELLMarch 2021December 2023Allow3410NoNo
17141454Remnant Tumor Infiltrating Lymphocytes and Methods of Preparing and Using the SameJanuary 2021December 2021Allow1221YesNo
15734939ANTIBODIES AGAINST AQUACULTURE DISEASE-CAUSING AGENTS AND USES THEREOFDecember 2020November 2024Abandon4821NoNo
16952678PD1 BINDING AGENTSNovember 2020February 2023Allow2700NoNo
17054193Serum BiomarkersNovember 2020June 2024Abandon4301NoNo
17086762PD1 BINDING AGENTSNovember 2020July 2023Allow3301NoNo
17078969CHIMERIC ANTIGEN RECEPTORS AND USES THEREOFOctober 2020April 2024Abandon4221NoNo
16997570CD3/CD25 Antibodies For Neuro-Immune DiseasesAugust 2020May 2021Allow911YesNo
16921400COMPOSITIONS AND METHODS FOR CAR T CELL THERAPYJuly 2020January 2023Allow3131YesNo
16911826PD1 BINDING AGENTSJune 2020September 2020Allow301YesNo
16912023PD1 BINDING AGENTSJune 2020September 2020Allow301YesNo
16958105CD3-DELTA/EPSILON HETERODIMER SPECIFIC ANTIBODIESJune 2020February 2024Abandon4321NoNo
16955608Antibodies To Tumour AntigensJune 2020December 2022Allow3010YesNo
16892651Method for Combination Cold Atmospheric Plasma and CAR-T TherapyJune 2020October 2024Abandon5231NoNo
16891672HETERODIMERIC PROTEINS FOR MODULATING GAMMA DELTA T CELLSJune 2020March 2021Allow921NoNo
16888427DOSING OF BISPECIFIC T CELL ENGAGERMay 2020June 2023Abandon3630NoYes
15931685Methods and Compositions for Preventing Type 1 DiabetesMay 2020July 2022Allow2630YesNo
16847059COMPOSITIONS AND METHODS FOR IMMUNOTHERAPYApril 2020March 2023Allow3501YesNo
16753577T CELL-ANTIGEN COUPLER WITH Y182T MUTATION AND METHODS AND USES THEREOFApril 2020January 2023Allow3310YesNo
16827302ENGINEERED PHAGOCYTIC RECEPTOR COMPOSITIONS AND METHODS OF USE THEREOFMarch 2020March 2021Allow1211YesNo
16827381ENGINEERED PHAGOCYTIC RECEPTOR COMPOSITIONS AND METHODS OF USE THEREOFMarch 2020March 2021Allow1211YesNo
16807742T CELL RECEPTORS THAT BIND TO MIXED LINEAGE LEUKEMIA (MLL)-SPECIFIC PHOSPHOPEPTIDES AND METHODS OF USE THEREOFMarch 2020March 2023Allow3611NoNo
16634325CD8 BINDING AGENTSJanuary 2020August 2022Allow3111YesNo
16632088RECOMBINANT CD123-BINDING ANTIBODIESJanuary 2020August 2022Allow3111YesNo
16741146HETERODIMERIC PROTEINS FOR MODULATING GAMMA DELTA T CELLSJanuary 2020June 2021Allow1721YesNo
16626233CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOFDecember 2019December 2024Allow5931NoNo
16715462CHIMERIC ANTIGEN RECEPTOR THAT BINDS HLA-DR AND CAR-T CELLDecember 2019April 2021Allow1611YesNo
16622791COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINSDecember 2019March 2024Abandon5131NoNo
16620530HUMANIZED DR4 ANTIBODY GENE HAVING APOPTOSIS-INDUCING ACTIVITY AND DUAL-ACTING CHIMERIC ANTIGEN RECEPTOR T CELL OR NATURAL KILLER CELL THERAPEUTIC AGENT USING SAMEDecember 2019January 2023Allow3721YesNo
16619212ANTIGEN-BINDING PROTEIN THAT RECOGNIZES MAGE-A4-DERIVED PEPTIDEDecember 2019August 2022Allow3310YesNo
16615411AGENTS WHICH INHIBIT GADS DIMERIZATION AND METHODS OF USE THEREOFNovember 2019July 2022Abandon3231NoNo
16615360CIRCULATING TUMOR CELL ENRICHMENT USING NEOEPITOPESNovember 2019May 2024Allow5441YesNo
16677207ANTI-PTK7 IMMUNE CELL CANCER THERAPYNovember 2019July 2024Allow5641YesNo
16497682Stimulatory Cell Lines For Ex Vivo Expansion And Activation Of Natural Killer CellsSeptember 2019September 2023Allow4831NoNo
16556524PLASMA KALLIKREIN INHIBITORS AND USES THEREOF FOR TREATING HEREDITARY ANGIOEDEMA ATTACKAugust 2019June 2022Abandon3330NoNo
16555198MODULATION OF CELL FUNCTION FOR IMMUNOTHERAPYAugust 2019February 2023Allow4211YesNo
16547910ANTI-FC EPSILON-R1 ALPHA (FCER1A) ANTIBODIES, BISPECIFIC ANTIGEN-BINDING MOLECULES THAT BIND FCER1A AND CD3, AND USES THEREOFAugust 2019October 2022Allow3811NoNo
16487335PREDICTION AND TREATMENT OF IMMUNOTHERAPEUTIC TOXICITYAugust 2019March 2023Allow4331YesNo
16543472METHODS FOR IN VIVO EXPANSION OF CD8+ T CELLS AND PREVENTION OR TREATMENT OF GVHDAugust 2019October 2024Abandon6051NoNo
16485598HLA-DR CAR-T COMPOSITIONS AND METHODS OF MAKING AND USING THE SAMEAugust 2019September 2023Abandon4921YesNo
16481976TREATMENT OF CANCER USING CHIMERIC T CELL RECEPTOR PROTEINS HAVING MULTIPLE SPECIFICITIESJuly 2019September 2023Abandon4921NoNo
16480987NYESO TCRJuly 2019October 2021Allow2700YesNo
16512031T CELL RECEPTORS THAT BIND TO NY-ESO-1 AND METHODS OF USE THEREOFJuly 2019November 2022Allow4011YesNo
16503984NATURAL KILLER CELL EXPRESSING ANTI-COTININE CHIMERIC ANTIGEN RECEPTORJuly 2019March 2023Allow4431YesNo
16472751ENGINEERED T CELLS FOR THE TREATMENT OF CANCERJune 2019August 2024Abandon6031YesNo
16467003METHODS AND COMPOSITIONS FOR VACCINATING AND BOOSTING CANCER PATIENTSJune 2019January 2022Abandon3141YesNo
16465141METHODS FOR DETERMINING CAR-T CELLS DOSINGMay 2019June 2025Abandon6061YesNo
16348378HIGH AFFINITY MERKEL CELL POLYOMAVIRUS T ANTIGEN-SPECIFIC TCRS AND USES THEREOFMay 2019February 2022Allow3301YesNo
16347743CD38-NAD+ REGULATED METABOLIC AXIS IN ANTI-TUMOR IMMUNOTHERAPYMay 2019September 2023Allow5331YesNo
16346226ARTIFICIAL ANTIGEN PRESENTING CELLS FOR EXPANDING IMMUNE CELLS FOR IMMUNOTHERAPYApril 2019July 2024Abandon6041NoNo
16343709SECRETABLE VARIANT IMMUNOMODULATORY PROTEINS AND ENGINEERED CELL THERAPYApril 2019November 2021Abandon3101NoNo
16388245ANTIGEN-BINDING PROTEINS TARGETING MELANOMA DIFFERENTIATION ANTIGENS AND USES THEREOFApril 2019December 2023Abandon5531NoNo
16339077Methods and Kits for Cell ActivationApril 2019July 2022Allow4011NoNo
16372506VHH ANTIBODYApril 2019November 2020Allow1911NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner HARTNETT, BRIAN.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
1
Examiner Affirmed
1
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.6%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
6
Allowed After Appeal Filing
2
(33.3%)
Not Allowed After Appeal Filing
4
(66.7%)
Filing Benefit Percentile
48.0%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 33.3% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner HARTNETT, BRIAN - Prosecution Strategy Guide

Executive Summary

Examiner HARTNETT, BRIAN works in Art Unit 1644 and has examined 145 patent applications in our dataset. With an allowance rate of 60.0%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 35 months.

Allowance Patterns

Examiner HARTNETT, BRIAN's allowance rate of 60.0% places them in the 13% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by HARTNETT, BRIAN receive 1.90 office actions before reaching final disposition. This places the examiner in the 60% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by HARTNETT, BRIAN is 35 months. This places the examiner in the 19% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +33.8% benefit to allowance rate for applications examined by HARTNETT, BRIAN. This interview benefit is in the 84% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 16.9% of applications are subsequently allowed. This success rate is in the 8% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 45.9% of cases where such amendments are filed. This entry rate is in the 64% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 66.7% of appeals filed. This is in the 42% percentile among all examiners. Of these withdrawals, 50.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 37.7% are granted (fully or in part). This grant rate is in the 35% percentile among all examiners. Strategic Note: Petitions show below-average success regarding this examiner's actions. Ensure you have a strong procedural basis before filing.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.