USPTO Examiner BELYAVSKYI MICHAIL A - Art Unit 1644

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18984595PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYDecember 2024July 2025Allow620NoNo
18957327PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYNovember 2024July 2025Allow820NoNo
18906588TEMPERATURE-RESPONSIVE VIRUS STORAGE SYSTEMOctober 2024April 2025Allow610NoNo
18903162PREPARATION OF A THERAPEUTIC COMPOSITION FOR TREATING AUTOIMMUNE DISEASESOctober 2024December 2025Allow1441YesNo
18742215METHOD FOR MAKING PLURIPOTENT STEM CELLSJune 2024September 2024Allow300NoNo
18734664MESENCHYMAL STEM CELLS TREATED BY AT LEAST TWO OF CYTOKINES IL4, IL21, AND IL27, EXOSOMES AND USES THEREOFJune 2024October 2025Abandon1621NoNo
18649790Adenoviral Vector Transduced Apheresis ProductApril 2024January 2025Allow921YesNo
18405885SELECTIVE IMMUNODEPLETION OF ENDOGENOUS STEM CELL NICHE FOR ENGRAFTMENTJanuary 2024November 2025Abandon2310NoNo
18386373ARTIFICIAL ANTIGEN-PRESENTING CELLS AND METHODS FOR PRODUCING AND USING THE SAMENovember 2023July 2025Allow2110NoNo
18381782TEMPERATURE-RESPONSIVE VIRUS STORAGE SYSTEMOctober 2023November 2025Allow2531YesYes
18358659GENETICALLY MODIFIED STEM CELLSJuly 2023May 2025Allow2110NoNo
18315782USING REPROGRAMMED, PERSONALIZED CANCER STEM CELLS AS A TRIPLE-KILLER CANCER TREATMENTMay 2023February 2025Abandon2121NoNo
18316198MODIFIED B CELLS AND METHODS OF USE THEREOFMay 2023March 2024Allow1021NoNo
18314778MODIFIED B CELLS AND METHODS OF USE THEREOFMay 2023October 2025Abandon3001NoNo
18309489CELL CULTURE METHOD USING AMINO ACID-ENRICHED MEDIUMApril 2023January 2026Abandon3311YesNo
18125691GLYCOSYLATED ANTIBODIESMarch 2023October 2025Allow3101NoNo
18246083TARGETED ANTIGEN DELIVERY SYSTEM AND USES THEREOFMarch 2023January 2026Allow3441YesNo
18174565COMPOSITIONS AND METHODS OF CELLULAR IMMUNOTHERAPYFebruary 2023September 2025Abandon3010YesNo
18166700Activatable Cytokine Polypeptides and Methods of Use ThereofFebruary 2023April 2024Allow1421YesNo
18106906REGULATORY B CELLS AND THEIR USESFebruary 2023September 2025Abandon3110NoNo
18087618SELECTIVE IMMUNODEPLETION OF ENDOGENOUS STEM CELL NICHE FOR ENGRAFTMENTDecember 2022October 2023Allow1010NoNo
18069421Peptide for Inducing Regeneration of Tissue and Use ThereofDecember 2022September 2025Abandon3301NoNo
18002109CHIMERIC ANTIGEN RECEPTOR TARGETING BCMA AND USE THEREOFDecember 2022February 2026Allow3801NoNo
18000096NOVEL CONJUGATE OF IMMUNE-STIMULATING IL-2 ANALOG AND PREPARATION METHOD THEREOFNovember 2022December 2025Allow3620YesNo
17999370METHOD FOR THE TREATMENT OF VIRUS INFECTION WITH IVIG AND CONVALESCENT PLASMANovember 2022March 2026Abandon3910NoNo
18057098STRATEGIES TO ASSESS AND/OR PRODUCE CELL POPULATIONS WITH PREDICTIVE ENGRAFTMENT POTENTIALNovember 2022December 2025Abandon3711NoNo
17926542Ferritin Heavy Chain Subunit-Based Conjugates and Application ThereofNovember 2022February 2026Abandon3910NoNo
17923732ANTI-CANCER PROTEINSNovember 2022March 2026Abandon4001NoNo
17921837ANTI-CANCER VACCINES AND RELATED THERAPYOctober 2022March 2026Allow4011YesNo
18050336Human Antibodies that Bind Lymphocyte Activation Gene-3 (LAG-3), and Uses ThereofOctober 2022September 2025Abandon3410NoNo
18047357MAMMALIAN CELLS COMPRISING INTEGRATED CAS9 GENES TO PRODUCE STABLE INTEGRATION SITES, AND MAMMALIAN CELLS COMPRISING STABLE INTEGRATION SITES AND OTHER SITESOctober 2022February 2026Allow4011NoNo
17919130Apoptosis inducing peptide (SSTP1)October 2022February 2026Allow4011NoNo
17938182PLASMID COMBINATION AND APPLICATION THEREOF IN PREPARING MODIFIED IMMUNE CELLSOctober 2022August 2025Allow3411YesNo
17936811EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT GAMMA DELTA T CELLS AND USES OF THESE CELLSSeptember 2022July 2025Allow3411YesNo
17934811ACTIVATABLE CYTOKINE POLYPEPTIDES AND METHODS OF USE THEREOFSeptember 2022April 2024Allow1921NoNo
17913751COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CORONAVIRUSESSeptember 2022January 2026Abandon4001NoNo
17948313ALLELE EDITING AND APPLICATIONS THEREOFSeptember 2022March 2025Allow3010NoNo
17931576CELLULAR TARGETED ACTIVE INGREDIENT DELIVERY SYSTEMSeptember 2022April 2024Allow1920NoNo
17910967METHODS AND USE OF CHIMERIC PROTEINSSeptember 2022November 2025Allow3810YesNo
17930231IMMUNOLOGICAL DETECTION OF ALTERED CELLSSeptember 2022March 2026Abandon4221NoNo
17823448PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022February 2024Allow1730YesNo
17823445PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022January 2024Allow1720NoNo
17823454PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022February 2024Allow1730NoNo
17823419PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022July 2024Allow2250NoNo
17821703NK CELLS OR T CELLS EXPRESSING HEMATOPOIETIC GROWTH FACTOR RECEPTORS AND METHODS OF USEAugust 2022May 2024Abandon2921NoNo
17817751HUMAN MONOCLONAL ANTIBODIES TO FUCOSYL-GM1 AND METHODS FOR USING ANTI-FUCOSYL-GM1 ANTIBODIESAugust 2022May 2025Allow3311NoNo
17817885COMPOSITION FOR DETERMINATION OF CELL-MEDIATED IMMUNE RESPONSIVENESSAugust 2022April 2025Abandon3210NoNo
17817217PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022May 2023Allow930NoNo
17817239PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022May 2023Allow930NoNo
17817247PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022June 2023Allow1020NoNo
17817279PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022October 2022Allow210NoNo
17817232PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022February 2023Allow630YesNo
17817273PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022June 2024Allow2240YesNo
17817276PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022October 2022Allow270NoNo
17817281PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022October 2022Allow210NoNo
17817226PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022November 2022Allow320NoNo
17817207PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYAugust 2022November 2022Allow430NoNo
17872741COMBINED ORGAN AND HEMATOPOIETIC CELLS FOR TRANSPLANTATION TOLERANCE OF GRAFTSJuly 2022February 2025Allow3010NoNo
17758947GENETICALLY ENGINEERED T CELLS EXPRESSING BCMA-SPECIFIC CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF IN CANCER THERAPYJuly 2022January 2026Abandon4201NoNo
17861534METHODS AND COMPOSITION FOR PRODUCING AND USING IMMUNE CELLS AND STEM CELLS FOR CELL-BASED THERAPIESJuly 2022July 2025Allow3611NoNo
17791137MULTISPECIFIC ANTI-CLAUDIN-18.2 CONSTRUCTS AND USES THEREOFJuly 2022January 2026Abandon4201NoNo
17856997GENERATING CIK NKT CELLS FROM CORD BLOODJuly 2022October 2023Allow1621YesNo
17856800PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022August 2022Allow210NoNo
17856793PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022April 2023Allow940NoNo
17856806PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022June 2023Allow1240YesNo
17810482CLOSED PROCESS FOR EXPANSION AND GENE EDITING OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022February 2023Allow820NoNo
17810540CLOSED PROCESS FOR EXPANSION AND GENE EDITING OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022March 2023Allow840YesNo
17810542CLOSED PROCESS FOR EXPANSION AND GENE EDITING OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022June 2023Allow1220YesNo
17810537CLOSED PROCESS FOR EXPANSION AND GENE EDITING OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYJuly 2022March 2023Allow820YesNo
17848590USE OF PRE T ALPHA OR FUNCTIONAL VARIANT THEREOF FOR EXPANDING TCR ALPHA DEFICIENT T CELLSJune 2022November 2025Allow4121YesNo
17786039LAG3 ANTAGONIST CELL BASED POTENCY ASSAYJune 2022December 2025Abandon4201NoNo
17842212SYSTEMS AND METHODS FOR CELL CULTURINGJune 2022January 2025Allow3110NoNo
17827089PREPARATION OF A THERAPEUTIC COMPOSITION FOR TREATING AUTOIMMUNE DISEASESMay 2022March 2025Abandon3371YesNo
17804239GENERATION OF CTL LINES WITH SPECIFICITY AGAINST MULTIPLE TUMOR ANTIGENS OR MULTIPLE VIRUSESMay 2022June 2025Allow3611NoNo
17825175METHODS OF DETERMINING PROGNOSIS OF SEPSIS AND TREATING SAMEMay 2022December 2025Abandon4311NoNo
17746097ANTIBODY PRODUCING MICROFLUIDIC DEVICESMay 2022December 2025Abandon4311NoNo
17734907Optimization of Antibodies that Bind Lymphocyte Activation Gene-3 (LAG-3), and Uses ThereofMay 2022March 2025Abandon3501NoNo
17769467MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING MYOTONIC DYSTROPHYApril 2022December 2025Abandon4401NoNo
17698920METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATIONMarch 2022March 2025Abandon3601NoNo
17691477METHODS FOR STEM CELL TRANSPLANTATIONMarch 2022March 2026Allow4820NoYes
17681665DEVELOPING AN EFFICIENT HYBRIDOMA PLATFORM FOR THERAPEUTIC ANTIBODY DISCOVERYFebruary 2022July 2025Allow4121NoNo
17669891ANTI-LAG3 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTSFebruary 2022May 2024Allow2700NoNo
17586698PROCESS FOR T CELL EXPANSIONJanuary 2022July 2025Allow4211NoNo
17628032COMPOSITION AND METHOD FOR ADOPTIVE IMMUNOTHERAPYJanuary 2022October 2025Allow4511NoNo
17578172SELECTIVE EXPANSION OF DIFFERENT SUBPOPULATIONS OF T CELLS BY THE ALTERATION OF CELL SURFACING SIGNALS AND SIGNAL RATIOJanuary 2022December 2024Allow3410NoNo
17574483TUMOR-ACTIVATED ALLOREACTIVE AND XENOREACTIVE T CELLS AND THEIR USE IN IMMUNOTHERAPY AGAINST CANCERJanuary 2022February 2026Allow4911NoNo
17569943CULTURE CONTAINER, METHOD FOR CULTURING LYMPHOCYTES, CULTURE-CONTAINER PRODUCTION METHOD, AND SOLID-PHASING APPARATUSJanuary 2022December 2024Allow3520YesNo
17567470BISPECIFIC ANTIBODIES FOR USE IN STEM CELL TRANSPLANTATIONJanuary 2022December 2024Abandon3510NoNo
17544542Human Antibodies that Bind Lymphocyte Activation Gene-3 (LAG-3), and Uses ThereofDecember 2021July 2022Allow810NoNo
17544534Human Antibodies that Bind Lymphocyte Activation Gene-3 (LAG-3), and Uses ThereofDecember 2021July 2022Allow710NoNo
17531983METHOD FOR DETECTING TARGET MOLECULENovember 2021August 2025Allow4511NoNo
17525714METHODS AND COMPOSITIONS FOR INFUSION OF TRANSIENTLY ENGRAFTING, SELECTED POPULATIONS OF ALLOGENEIC LYMPHOCYTES TO TREAT CANCERNovember 2021March 2025Allow4011NoNo
17522538GENETICALLY MODIFIED STEM CELLSNovember 2021April 2023Allow1720NoNo
17504656CONDITIONING AGENTS FOR USE IN ALLOGENEIC HEMATOPOETIC STEM CELL TRANSPLANTATIONOctober 2021August 2025Allow4631YesNo
17494633T CELL MANUFACTURING COMPOSITIONS AND METHODSOctober 2021November 2024Allow3711NoNo
17493411STEM CELL FACTOR INHIBITOROctober 2021December 2024Abandon3801NoNo
17490691ACTIVATION OF MARROW INFILTRATING LYMPHOCYTES IN HYPOXIC ALTERNATING WITH NORMOXIC CONDITIONSSeptember 2021November 2024Allow3710NoNo
17480525PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYSeptember 2021February 2022Allow410NoNo
17480596PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYSeptember 2021April 2022Allow710NoNo
17480587PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPYSeptember 2021February 2022Allow510NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner BELYAVSKYI, MICHAIL A.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
34
Examiner Affirmed
19
(55.9%)
Examiner Reversed
15
(44.1%)
Reversal Percentile
66.9%
Higher than average

What This Means

With a 44.1% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
210
Allowed After Appeal Filing
40
(19.0%)
Not Allowed After Appeal Filing
170
(81.0%)
Filing Benefit Percentile
23.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 19.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner BELYAVSKYI, MICHAIL A - Prosecution Strategy Guide

Executive Summary

Examiner BELYAVSKYI, MICHAIL A works in Art Unit 1644 and has examined 1,454 patent applications in our dataset. With an allowance rate of 55.7%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 35 months.

Allowance Patterns

Examiner BELYAVSKYI, MICHAIL A's allowance rate of 55.7% places them in the 16% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by BELYAVSKYI, MICHAIL A receive 1.84 office actions before reaching final disposition. This places the examiner in the 43% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by BELYAVSKYI, MICHAIL A is 35 months. This places the examiner in the 38% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +37.0% benefit to allowance rate for applications examined by BELYAVSKYI, MICHAIL A. This interview benefit is in the 85% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 22.4% of applications are subsequently allowed. This success rate is in the 28% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 33.7% of cases where such amendments are filed. This entry rate is in the 50% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 26.7% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 30% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 73.0% of appeals filed. This is in the 61% percentile among all examiners. Of these withdrawals, 73.9% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 50.0% are granted (fully or in part). This grant rate is in the 46% percentile among all examiners. Strategic Note: Petitions show below-average success regarding this examiner's actions. Ensure you have a strong procedural basis before filing.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 5.0% of allowed cases (in the 86% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.5% of allowed cases (in the 55% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.