USPTO Examiner ROARK JESSICA HOPE - Art Unit 1643

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18432567METHOD OF MODIFYING ISOELECTRIC POINT OF ANTIBODY VIA AMINO ACID SUBSTITUTION IN CDRFebruary 2024August 2024Allow710NoNo
18425859METHOD OF MODIFYING ISOELECTRIC POINT OF ANTIBODY VIA AMINO ACID SUBSTITUTION IN CDRJanuary 2024August 2024Allow610YesNo
18575650ANTIGEN-BINDING POLYPEPTIDE TARGETING B7H3 AND APPLICATION THEREOFDecember 2023August 2024Allow810NoNo
18396466METHODS OF MANUFACTURING DIMERIC ANTIBODIESDecember 2023July 2024Allow710NoNo
18396418DIMERIC ANTIBODIESDecember 2023July 2024Allow710NoNo
18503245PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-HUMAN TSLP RECEPTOR ANTIBODIES AND METHODS OF USING THE SAMENovember 2023July 2024Allow810NoNo
18314091Antigen Binding Molecules Targeting SARS-CoV-2May 2023October 2023Abandon610NoNo
18313306Antigen Binding Molecules Targeting SARS-CoV-2May 2023December 2023Allow710NoNo
18061533ANTIGEN-BINDING PROTEIN AND USE THEREOFDecember 2022March 2023Allow300NoNo
17821182LYMPHOCYTES-ANTIGEN PRESENTING CELLS CO-STIMULATORS AND USES THEREOFAugust 2022March 2023Allow701YesNo
17809409COMPOSITIONS AND METHODS FOR TREATING HER2 POSITIVE CANCERSJune 2022April 2023Allow910NoNo
17834497ANTI-LAG-3 ANTIBODIES AND COMPOSITIONSJune 2022July 2023Allow1310YesNo
17499687ANTI TRBC1 ANTIGEN BINDING DOMAINSOctober 2021April 2022Allow610NoNo
17484452IMMUNOTHERAPY WITH B*08 RESTRICTED PEPTIDES AND COMBINATION OF PEPTIDES AGAINST CANCERS AND RELATED METHODSSeptember 2021May 2022Allow710NoNo
17478370COMBINATION THERAPIES COMPRISING ANTIBODY MOLECULES TO TIM-3September 2021February 2025Abandon4101NoNo
17477889ANTI-PD-1 ANTIBODIES AND USES THEREOFSeptember 2021February 2025Abandon4110NoNo
17471271D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOFSeptember 2021February 2022Allow500YesNo
17471206D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOFSeptember 2021August 2022Allow1110NoNo
17402300LYM-1 AND LYM-2 ANTIBODY COMPOSITIONS AND IMPROVED CAR CONSTRUCTSAugust 2021March 2022Allow700YesNo
17391888CD47 ANTIBODIES AND METHODS OF USE THEREOFAugust 2021January 2025Abandon4120NoNo
17353087ANTIBODIESJune 2021December 2023Allow3000YesNo
17352652CELL INJURY INDUCING THERAPEUTIC DRUG FOR USE IN CANCER THERAPYJune 2021February 2025Abandon4401NoNo
17311591METHODS OF USING TUMOR INFILTRATING LYMPHOCYTES IN DOUBLE-REFRACTORY MELANOMAJune 2021February 2025Abandon4401NoNo
17327170ANTI-AP2 ANTIBODIES AND ANTIGEN BINDING AGENTS TO TREAT METABOLIC DISORDERSMay 2021November 2024Allow4110NoNo
17309252HUMANIZED ANTI-HUMAN PD-L1 MONOCLONAL ANTIBODY AND PREPARATION METHOD THEREFOR AND USE THEREOFMay 2021July 2024Allow3811NoNo
17306241Antigen-Binding Constructs Targeting HER2May 2021October 2024Allow4111NoNo
17289244NOVEL METHOD FOR PRODUCING ANTIBODIESApril 2021February 2025Abandon4601NoNo
17288845T CELLS WITH SUICIDE SWITCHApril 2021February 2025Abandon4601NoNo
17287828MULTIVALENT IgM- AND IgA-Fc-BASED BINDING MOLECULESApril 2021January 2025Abandon4501NoNo
17228023ANTIBODIESApril 2021July 2021Allow310NoNo
17225273CYTOTOXICITY-INDUCING THERAPEUTIC AGENTApril 2021November 2024Abandon4301NoNo
17223935Multi-Specific MoleculesApril 2021February 2022Allow1020YesNo
17203291CANNABINOID RECEPTOR TYPE 1 (CB1) BINDING PROTEINS AND USES THEREOFMarch 2021November 2021Allow810YesNo
17199258ANTIBODIES TARGETING A COMPLEX COMPRISING NON-CLASSICAL HLA-I AND NEOANTIGEN AND THEIR METHODS OF USEMarch 2021December 2023Allow3410NoNo
17187074CHIMERIC ANTIGEN RECEPTORS AND METHODS OF MAKINGFebruary 2021April 2024Allow3710NoNo
17250725PEPTIDE VACCINESFebruary 2021February 2023Allow2300YesNo
17170854NON-PLATELET DEPLETING AND NON-RED BLOOD CELL DEPLETING CD47 ANTIBODIES AND METHODS OF USE THEREOFFebruary 2021November 2023Abandon3410NoNo
17248367TREATMENT OF LUNG CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND ANOTHER ANTI-CANCER AGENTJanuary 2021December 2024Abandon4620NoNo
17150884ANTIBODY THERAPEUTICS THAT BIND CD123January 2021April 2023Allow2700NoNo
17148450Antigen Binding Proteins that Bind PD-L1January 2021October 2023Allow3300NoNo
17260213HEAVY CHAIN ANTIBODIES BINDING TO CD19January 2021September 2024Allow4420NoNo
17116822Subcutaneous Formulations Of Anti-CD38 Antibodies And Their UsesDecember 2020May 2023Allow2910YesNo
17116835Subcutaneous Formulations Of Anti-CD38 Antibodies And Their UsesDecember 2020May 2023Allow2910YesNo
17107302CHIMERIC RECEPTORS AND METHODS OF USE THEREOFNovember 2020February 2024Abandon3910NoNo
17059745CAR T CELLS THAT TARGET B-CELL ANTIGENSNovember 2020March 2024Allow4011NoNo
17058794Biomarkers for determining the effectiveness of immune checkpoint inhibitorsNovember 2020July 2024Allow4421NoNo
17100428Sialylated GlycoproteinsNovember 2020September 2023Abandon3410NoNo
17098180COMBINATION OF IMMUNOTHERAPY WITH LOCAL CHEMOTHERAPY FOR THE TREATMENT OF MALIGNANCIESNovember 2020June 2023Allow3110YesNo
17054994NOVEL LEUCINE-RICH REPEAT NEURONAL PROTEIN 1 (LRRN1) ANTIBODIES AND USES THEREOFNovember 2020April 2024Abandon4110NoNo
17054670CHIMERIC ANTIGEN RECEPTORNovember 2020December 2023Allow3710NoNo
17092817VISTA Antagonist and Methods of UseNovember 2020January 2024Abandon3811NoNo
17088765ANTI-CD37 ANTIBODIESNovember 2020November 2023Abandon3710NoNo
17077376ANTIBODIESOctober 2020January 2021Allow300NoNo
17033452Sialylated GlycoproteinsSeptember 2020September 2023Abandon3610NoNo
17032994Sialylated GlycoproteinsSeptember 2020September 2023Abandon3610NoNo
16997757METHOD FOR DECREASING IMMUNOGENICITYAugust 2020February 2024Abandon4201NoNo
16994065MATERIALS AND METHODS FOR IMPROVED SINGLE CHAIN VARIABLE FRAGMENTSAugust 2020June 2023Allow3411YesNo
16986913CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE THEREOFAugust 2020September 2024Allow4930YesNo
16986214Anti-CD38 Antibodies for Treatment of Light Chain Amyloidosis and Other CD38-Positive Hematological MalignanciesAugust 2020June 2024Allow4630YesNo
16942531THERAPEUTIC CD47 ANTIBODIESJuly 2020June 2023Abandon3510NoNo
16965287COMBINATION THERAPY USING ADOPTIVE CELL THERAPY AND CHECKPOINT INHIBITORJuly 2020February 2025Abandon5521YesNo
16963091ANTI-CD73 ANTI-PD-L1 BISPECIFIC ANTIBODIESJuly 2020February 2021Allow720NoNo
16962755Regulatory T Cell Expressing a Chimeric Antigen ReceptorJuly 2020August 2024Allow4921NoNo
16927339Antibodies Directed Against Programmed Death-1(PD-1)July 2020August 2023Abandon3701NoNo
16927947Subcutaneous Formulations Of Anti-CD38 Antibodies And Their UsesJuly 2020June 2023Allow3510YesNo
16927675TREATMENT OF BRAIN CANCERS USING CENTRAL NERVOUS SYSTEM MEDIATED GENE TRANSFER OF MONOCLONAL ANTIBODIESJuly 2020June 2024Allow4741YesNo
16926355ANTIBODIES TARGETING A COMPLEX COMPRISING NON-CLASSICAL HLA-I AND NEOANTIGEN AND THEIR METHODS OF USEJuly 2020January 2021Allow601YesNo
16925980ANTIBODY MOLECULES TO PD-1 AND USES THEREOFJuly 2020July 2023Allow3610NoNo
16919846ANTI-PD-1 ANTIBODIES AND USES THEREOFJuly 2020April 2021Allow1011NoNo
16919020THYMIC STROMAL LYMPHOPOIETIN (TSLP)-BINDING MOLECULES AND METHODS OF USING THE MOLECULESJuly 2020November 2022Allow2900NoNo
16956807ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF THAT SPECIFICALLY RECOGNIZES B CELL MALIGNANCIES, CHIMERIC ANTIGEN RECEPTOR COMPRISING SAME, AND USES THEREOFJune 2020May 2023Allow3410NoNo
16770019METHODS FOR ENHANCING AND MAINTAINING CAR-T CELL EFFICACYJune 2020June 2024Abandon4911NoNo
16769867T-CELLS COMPRISING TWO DIFFERENT CHIMERIC ANTIGEN RECEPTORS AND USES THEREOFJune 2020July 2024Allow4921NoNo
16768575METHODS FOR DOSING AND FOR MODULATION OF GENETICALLY ENGINEERED CELLSMay 2020October 2023Abandon4110NoNo
16767470ANTI-CD33 AND ANTI-CD7 COMBINATION TREATMENTMay 2020June 2023Allow3721YesNo
16877150BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULESMay 2020November 2022Abandon3010NoNo
16763784D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOFMay 2020March 2022Allow2201NoNo
16872158ANTI-PD-L1 ANTIBODIES AND DIAGNOSTIC USES THEREOFMay 2020August 2022Allow2710NoNo
16759490MOLECULAR SWITCH-MEDIATED CONTROL OF ENGINEERED CELLSApril 2020September 2023Allow4121NoNo
16851691ANTIBODIES AGAINST 4G7-DERIVED CHIMERIC ANTIGEN RECEPTORSApril 2020March 2023Allow3510NoNo
16844759NUCLEIC ACID MOLECULES ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING B-CELL MATURATION ANTIGEN AND USES THEREOFApril 2020June 2020Allow200NoNo
16840153Subcutaneous Formulations Of Anti-CD38 Antibodies And Their UsesApril 2020December 2022Allow3220YesNo
16821551CHIMERIC ANTIGEN RECEPTORS FOR PHAGOCYTOSISMarch 2020March 2021Allow1200YesNo
16819778COMPOSITIONS AND METHODS FOR TREATING DISEASESMarch 2020August 2022Abandon2910NoNo
16813167ANTIBODIESMarch 2020January 2025Abandon5951NoYes
16645290UNIVERSAL CHIMERIC ANTIGEN RECEPTOR T-CELL PREPARATION TECHNIQUEMarch 2020April 2024Allow4911NoNo
16787931METHODS OF TREATING CEA-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-CEA/ANTI-CD3 BISPECIFIC ANTIBODIESFebruary 2020September 2023Abandon4410NoNo
16784170CHIMERIC ANTIGEN RECEPTOR COMPOSITIONSFebruary 2020June 2023Abandon4010NoNo
16777053HETERODIMERIC ANTIBODY FC-CONTAINING PROTEINS AND METHODS FOR PRODUCTION THEREOFJanuary 2020August 2023Allow4210NoNo
16773927BISPECIFIC ANTIBODIES AGAINST CD3EPSILON AND ROR1January 2020October 2022Abandon3310NoNo
16632091CHIMERIC ANTIGEN RECEPTORS WITH ENHANCED NFKB SIGNALINGJanuary 2020July 2022Allow3020NoNo
16622636COMPOSITIONS AND METHODS TARGETING COMPLEMENT COMPONENT 3 FOR INHIBITING TUMOR GROWTHDecember 2019September 2023Allow4521NoNo
16620370ANTI TRBC1 ANTIGEN BINDING DOMAINSDecember 2019April 2022Allow2810NoNo
16703484THERAPEUTIC CD47 ANTIBODIESDecember 2019October 2022Allow3520NoNo
16611772METHODS TO AUGMENT OR ALTER SIGNAL TRANSDUCTIONNovember 2019April 2024Abandon5311NoNo
16608362CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTORS AND SECONDARY EFFECTORS AND USES THEREOFOctober 2019September 2022Abandon3501NoNo
16663583ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOFOctober 2019June 2023Allow4321NoYes
16608336CHIMERIC ANTIBODY/T-CELL RECEPTOR CONSTRUCTS AND USES THEREOFOctober 2019December 2022Allow3711NoNo
16659797ANTI-TIGIT ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOFOctober 2019October 2022Allow3611NoNo
16658480CHIMERIC RECEPTORS AND METHODS OF USE THEREOFOctober 2019June 2023Abandon4420NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner ROARK, JESSICA HOPE.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
6
Examiner Affirmed
5
(83.3%)
Examiner Reversed
1
(16.7%)
Reversal Percentile
26.3%
Lower than average

What This Means

With a 16.7% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
44
Allowed After Appeal Filing
6
(13.6%)
Not Allowed After Appeal Filing
38
(86.4%)
Filing Benefit Percentile
13.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 13.6% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner ROARK, JESSICA HOPE - Prosecution Strategy Guide

Executive Summary

Examiner ROARK, JESSICA HOPE works in Art Unit 1643 and has examined 652 patent applications in our dataset. With an allowance rate of 60.0%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 31 months.

Allowance Patterns

Examiner ROARK, JESSICA HOPE's allowance rate of 60.0% places them in the 13% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by ROARK, JESSICA HOPE receive 1.83 office actions before reaching final disposition. This places the examiner in the 56% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by ROARK, JESSICA HOPE is 31 months. This places the examiner in the 34% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +32.7% benefit to allowance rate for applications examined by ROARK, JESSICA HOPE. This interview benefit is in the 84% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 21.0% of applications are subsequently allowed. This success rate is in the 16% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 46.3% of cases where such amendments are filed. This entry rate is in the 65% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 71.4% of appeals filed. This is in the 53% percentile among all examiners. Of these withdrawals, 73.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 68.4% are granted (fully or in part). This grant rate is in the 86% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.2% of allowed cases (in the 48% percentile). This examiner makes examiner's amendments less often than average. You may need to make most claim amendments yourself.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.0% of allowed cases (in the 56% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.