USPTO Examiner HECK BRYAN WILLIAM - Art Unit 1643

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19284312ANTIGEN-BINDING PROTEINS AND RELATED METHODS OF USEJuly 2025February 2026Allow710YesNo
19081458PROTEASE-CLEAVABLE SUBSTRATES AND METHODS OF USE THEREOFMarch 2025October 2025Allow710NoNo
18989801Anti-PD-1 Antibodies and Fusion ProteinsDecember 2024November 2025Allow1011YesNo
18807097METHODS OF MANUFACTURING DIMERIC ANTIBODIESAugust 2024February 2025Allow610NoNo
18154761ANTI-CCR8 ANTIBODIESJanuary 2023March 2026Allow3800YesNo
18011878Anti-PD-1 Antibodies and Fusion ProteinsDecember 2022October 2025Abandon3410NoNo
18060135CD38 MODULATING ANTIBODYNovember 2022January 2025Allow2610NoNo
18053868CD20-PD1 BINDING MOLECULES AND METHODS OF USE THEREOFNovember 2022October 2025Allow3521YesNo
17953930LUNG-TARGETING SINGLE-DOMAIN ANTIBODIES AND PURIFICATION METHODSSeptember 2022June 2025Allow3221YesNo
17933954HETERODIMERIC Fc FOR MAKING FUSION PROTEINS AND BISPECIFIC ANTIBODIESSeptember 2022May 2025Allow3111YesNo
17906718GPC3 CAR- T CELL COMPOSITIONS AND METHODS OF MAKING AND USING THE SAMESeptember 2022December 2025Allow3910NoNo
17932178METHOD FOR IMPROVING AFFINITY OF ANTI-CYTOKINE ANTIBODY FOR ANTIGEN, METHOD FOR PRODUCING ANTI-CYTOKINE ANTIBODY, AND ANTI-CYTOKINE ANTIBODYSeptember 2022July 2025Abandon3411NoNo
17904057CHIMERIC ANTIGEN RECEPTOR TARGETING B-CELL MATURATION ANTIGEN AND USE THEREOFAugust 2022March 2026Abandon4310NoNo
17861179SYNTHETIC IL-7 AND IL-7 IMMUNOCYTOKINESJuly 2022September 2025Abandon3811NoNo
17698889CHIMERIC CELLS COMPRISING DENDRITIC CELLS AND ENDOTHELIAL CELLS RESEMBLING TUMOR ENDOTHELIUMMarch 2022April 2025Abandon3710NoNo
17686261Dimeric Antigen Receptors (DAR) that Bind BCMAMarch 2022February 2026Abandon4701NoNo
17676654TREATING MYELOMASFebruary 2022February 2026Abandon4810NoNo
17588086BISPECIFIC ANTI LRRC15 AND CD3EPSILON ANTIBODIESJanuary 2022March 2026Abandon4910NoNo
17631075T CELL RECEPTOR FOR RECOGNIZING SSX2 ANTIGEN SHORT PEPTIDEJanuary 2022January 2026Allow4810NoNo
17586652ENGINEERED HIGH-AFFINITY HUMAN T CELL RECEPTORSJanuary 2022November 2025Abandon4610NoNo
17618747COMPOSITIONS AND METHODS FOR TREATING CANCERDecember 2021February 2026Abandon5010NoNo
17536663CCL20 AS A PREDICTOR OF CLINICAL RESPONSE TO IL23-ANTAGONISTSNovember 2021January 2026Abandon4910NoNo
17613632METHOD OF PROVIDING SAFE ADMINISTRATION OF AN ANTI-CD40 ANTIBODYNovember 2021December 2025Abandon4910NoNo
17611551ANTIBODY AGAINST CLAUDIN 18A2 AND USE THEREOFNovember 2021July 2025Allow4420YesNo
17611231METHOD TO TREAT TYPE 2 INFLAMMATION OR MAST-CELL DEPENDENT DISEASENovember 2021December 2025Abandon4910NoNo
17611054EPCAM BINDING PROTEINS AND METHODS OF USENovember 2021April 2025Allow4200YesNo
17608738CLL-1 TARGETED IMMUNOTHERAPIESNovember 2021May 2025Allow4310NoNo
17512961COMBINATION THERAPIESOctober 2021August 2025Abandon4610NoNo
17606103Rank Pathway Inhibitors in Combination with CDK InhibitorsOctober 2021August 2025Abandon4610NoNo
17507531ANTHRACYCLINE ANTIBODY-DRUG CONJUGATES AND USES THEREOFOctober 2021May 2025Abandon4301NoNo
17605290ENGINEERED CELLS AND USES THEREOFOctober 2021September 2025Abandon4711NoNo
17594532ANTIBODY FORMULATIONOctober 2021October 2025Abandon4810NoNo
17604555ANTI-PD-1 ANTIBODIES AND USES THEREOFOctober 2021May 2025Allow4310NoNo
17604505BIOASSAY FOR T-CELL CO-STIMULATORY PROTEINS CONTAINING FC DOMAINSOctober 2021November 2025Abandon4911NoNo
17603761ANTI AQP3 MONOCLONAL ANTIBODY SPECIFICALLY BINDING TO EXTRACELLULAR DOMAIN OF AQUAPORIN 3 (AQP3) AND USE THEREOFOctober 2021May 2025Abandon4301NoNo
17603444DAF-MCP CHIMERIC PROTEINS, PROCESS TO MANUFACTURE THE SAME AND USE OF THE CHIMERIC PROTEIN FOR TREATING PATHOLOGICAL CONDITIONS INVOLVING THE COMPLEMENT SYSTEMOctober 2021February 2026Allow5220YesNo
17600893HIV/HCV CROSS-REACTIVE ANTIBODIES AND USES THEREOFOctober 2021September 2025Allow4811NoNo
17600095METHODS AND COMPOSITIONS INVOLVING CHIMERIC BINDING POLYPEPTIDESSeptember 2021September 2025Abandon4811NoNo
17599377Engineered Variant Antibodies that Bind CD38September 2021June 2025Abandon4510NoNo
17441519GLYPICAN-3 (GPC-3) ANTIBODIESSeptember 2021April 2025Allow4320YesNo
17439974FUSION PROTEIN COMPRISING ANTI-MESOTHELIN ANTIBODY, ANTI-CD3 ANTIBODY OR ANTI-EGFR ANTIBODY, BISPECIFIC OR TRISPECIFIC ANTIBODY COMPRISING SAME, AND USES THEREOFSeptember 2021September 2025Allow4811YesNo
17436936T CELL RECEPTORS AND METHODS OF USE THEREOFSeptember 2021October 2025Allow5001YesNo
17310957ANTI-FXI/FXIA ANTIBODY AND USE THEREOFSeptember 2021December 2024Allow4001YesNo
17298817ANTI-HUMAN TIM-3 MONOCLONAL ANTIBODY AND APPLICATION THEREOFAugust 2021September 2025Abandon5210NoNo
17403406ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOFAugust 2021March 2025Allow4311NoNo
17430540CANCER IMMUNOTHERAPY USING COMBINATIONS OF CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTORS AND MONOCLONAL ANTIBODIESAugust 2021January 2026Abandon5321NoNo
17399729Activatable Anti-CTLA-4 Antibodies and Uses ThereofAugust 2021June 2025Allow4611NoNo
17429672ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) INHIBITORY ANTIBODY AND USES THEREOFAugust 2021February 2025Allow4310YesNo
17331768Chimeric antigen receptor with a spacer comprising C2-set Ig-like domainsMay 2021March 2025Allow4610YesNo
17058889POLYPEPTIDE COMPRISING IL-1R1 BINDING DOMAIN AND CARRYING MOIETYNovember 2020September 2025Abandon5821NoNo
16867296COMBINATION TUMOR IMMUNOTHERAPYMay 2020December 2025Abandon6050NoNo

Appeals Overview

No appeal data available for this record. This may indicate that no appeals have been filed or decided for applications in this dataset.

Examiner HECK, BRYAN WILLIAM - Prosecution Strategy Guide

Executive Summary

Examiner HECK, BRYAN WILLIAM works in Art Unit 1643 and has examined 31 patent applications in our dataset. With an allowance rate of 45.2%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 47 months.

Allowance Patterns

Examiner HECK, BRYAN WILLIAM's allowance rate of 45.2% places them in the 9% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by HECK, BRYAN WILLIAM receive 1.13 office actions before reaching final disposition. This places the examiner in the 12% percentile for office actions issued. This examiner issues significantly fewer office actions than most examiners.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by HECK, BRYAN WILLIAM is 47 months. This places the examiner in the 9% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +77.3% benefit to allowance rate for applications examined by HECK, BRYAN WILLIAM. This interview benefit is in the 99% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 40.0% of applications are subsequently allowed. This success rate is in the 90% percentile among all examiners. Strategic Insight: RCEs are highly effective with this examiner compared to others. If you receive a final rejection, filing an RCE with substantive amendments or arguments has a strong likelihood of success.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 100.0% of cases where such amendments are filed. This entry rate is in the 98% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Petition Practice

When applicants file petitions regarding this examiner's actions, 85.7% are granted (fully or in part). This grant rate is in the 86% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 14.3% of allowed cases (in the 91% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • RCEs are effective: This examiner has a high allowance rate after RCE compared to others. If you receive a final rejection and have substantive amendments or arguments, an RCE is likely to be successful.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.