USPTO Examiner DUFFY BRADLEY - Art Unit 1643

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18774123DOSING REGIMEN FOR TREATING INFLAMMATORY BOWEL DISEASEJuly 2024April 2025Allow911YesNo
18067948CHIMERIC POLYPEPTIDE ASSEMBLY AND METHODS OF MAKING AND USING THE SAMEDecember 2022January 2024Allow1201NoNo
17929655COMBINATIONS OF IMMUNOTHERAPIES AND USES THEREOFSeptember 2022March 2025Abandon3130YesNo
17719894FUSION PROTEINS THAT FACILITATE CANCER CELL DESTRUCTIONApril 2022April 2025Allow3601NoNo
17689388CD19 BINDING AGENTS AND USES THEREOFMarch 2022January 2025Abandon3401NoNo
17682633CELL SURFACE COUPLING OF NANOPARTICLESFebruary 2022May 2025Abandon3810NoNo
17680174Anti-CD30 monoclonal antibodies and chimeric antigen receptorsFebruary 2022August 2023Allow1811YesNo
17670718METHOD FOR CONTROLLING AFFINITY OF ANTIBODY FOR ANTIGEN, ANTIBODY WHOSE AFFINITY FOR ANTIGEN HAS BEEN ALTERED, AND ITS PRODUCTION METHODFebruary 2022February 2025Allow3601NoNo
17666018Humanized anti-DKK2 antibody and uses thereofFebruary 2022December 2024Abandon3501NoNo
17645737VACCINEDecember 2021March 2022Allow300YesNo
17645741VACCINEDecember 2021November 2022Allow1120YesNo
17542948Anti-TfR1 Antibody MAb11-22.1 Conjugates for Cancer TreatmentDecember 2021January 2024Allow2611YesNo
17530211GENETICALLY MODIFIED NK-92 CELLS HAVING A SAFETY SWITCHNovember 2021April 2025Allow4021NoNo
17525512HUMAN MONOCLONAL ANTIBODY HUMAN CD134 (OX40) AND METHODS OF MAKING AND USING SAMENovember 2021February 2025Allow3910NoNo
17518123CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA AND METHODS OF USE THEREOFNovember 2021November 2024Allow3710NoNo
17488698METHOD FOR GENERATING AVID-BINDING MULTISPECIFIC ANTIBODIESSeptember 2021July 2025Allow4510YesNo
17405104ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) IMMUNOADHESIN MICROBODYAugust 2021February 2024Allow3001YesNo
17431664Bispecific Fusion Protein Using Orthopoxvirus Major Histocompatibility Complex (MHC) Class I-Like Protein (OMCP) and Tumor-Specific Binding PartnerAugust 2021May 2025Abandon4511NoNo
17383765Anti-Abeta AntibodiesJuly 2021June 2025Allow4631YesNo
17305577FUSION CONSTRUCTS AND METHODS OF USING THEREOFJuly 2021August 2024Allow3821YesNo
17351724Combination Therapy for the Treatment of CancerJune 2021May 2025Abandon4721NoNo
17328118CD70 Binding Molecules and Methods of Use ThereofMay 2021August 2024Allow3911NoNo
17318590CELL SURFACE COUPLING OF NANOPARTICLESMay 2021October 2021Allow500NoNo
17317824AFFINITY ENTITIES COMPRISING A TCR-LIKE ANTIBODY BINDING DOMAIN WITH HIGH AFFINITY AND FINE SPECIFICITY AND USES OF SAMEMay 2021November 2024Allow4201YesNo
17307158COMPOSITIONS AND METHODS FOR TREATING CANCERMay 2021May 2025Abandon4811NoNo
17235805IMMUNOGLOBULIN VARIANTS AND USES THEREOFApril 2021August 2024Abandon4010NoNo
17227536Tetravalent Antibody-Drug Conjugates and Use ThereofApril 2021December 2023Allow3200YesNo
17217839GENETICALLY MODIFIED NK-92 CELLS AND MONOCLONAL ANTIBODIES FOR THE TREATMENT OF CANCERMarch 2021August 2021Allow510NoNo
17210124Antibodies Targeted to Fungal Cell Wall PolysaccharidesMarch 2021November 2024Abandon4401NoNo
17200322EGFR-DIRECTED CAR THERAPY FOR GLIOBLASTOMAMarch 2021August 2024Abandon4101NoNo
17198179ANTI P2X7 RECEPTOR ANTIBODIES AND FRAGMENTS THEREOFMarch 2021June 2024Allow3911NoNo
17176858METHOD FOR ENGINEERING IMMUNOGLOBULINSFebruary 2021June 2024Abandon4010NoNo
17268174CANCER STEM CELL MARKER AND CANCER STEM CELL TARGETING DRUGFebruary 2021April 2025Abandon5111NoNo
17172694BINDING AGENTS BINDING TO PD-L1 AND CD137 AND USE THEREOFFebruary 2021May 2022Allow1521YesNo
17172700BINDING AGENTS BINDING TO PD-L1 AND CD137 AND USE THEREOFFebruary 2021January 2025Allow4811NoNo
17168100CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA AND METHODS OF USE THEREOFFebruary 2021October 2021Allow811YesNo
17264735MULTISPECIFIC TREG BINDING MOLECULESJanuary 2021October 2024Abandon4501NoNo
17151911BIOLOGICAL PRODUCTSJanuary 2021December 2023Abandon3410NoNo
17150272B CELL MATURATION ANTIGEN BINDING PROTEINSJanuary 2021January 2024Allow3611NoNo
17148337MULTISPECIFIC TREG BINDING MOLECULESJanuary 2021April 2023Abandon2701NoNo
17121622Polypeptides With Enhanced Anti-Inflammatory And Decreased Cytotoxic Properties And Relating MethodsDecember 2020November 2024Abandon4711NoNo
17104983CHIMERIC ANTIGEN RECEPTORS AND USES THEREOFNovember 2020July 2024Allow4422YesNo
17103190USE OF HEXOKINASE-2 IN DETECTION OF RARE TUMOR CELLS IN BODY FLUID SAMPLE AND KITNovember 2020October 2021Allow1021NoNo
17084156THERAPEUTIC CD47 ANTIBODIESOctober 2020October 2023Abandon3601NoNo
17051731METHODS AND SYSTEMS FOR SELECTION AND TREATMENT OF PATIENTS WITH INFLAMMATORY DISEASESOctober 2020November 2024Allow4811YesNo
17078903TREATMENT OF CANCER USING GFR ALPHA-4 CHIMERIC ANTIGEN RECEPTOROctober 2020January 2024Allow3821YesNo
17048739Switch Molecule And Switchable Chimeric Antigen ReceptorOctober 2020January 2024Allow3941YesNo
17032482DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASISSeptember 2020May 2023Allow3201YesNo
17040426COMBINATION OF NEAR INFRARED PHOTOIMMUNOTHERAPY TARGETING CANCER CELLS AND HOST-IMMUNE ACTIVATIONSeptember 2020January 2025Abandon5231NoNo
16982723FC VARIANT COMPOSITIONS AND METHODS OF USE THEREOFSeptember 2020February 2024Abandon4121NoNo
17025980PRODUCTION OF HETEROMULTIMERIC PROTEINSSeptember 2020June 2023Abandon3210NoNo
17023835Modified Cell with Enhanced Functionality and Cellular Therapy thereofSeptember 2020July 2023Allow3411YesNo
17021423Anti-MET Antibodies and Methods of Use ThereofSeptember 2020September 2023Allow3611NoNo
16980816BISPECIFIC ANTIBODY CAR CELL IMMUNOTHERAPYSeptember 2020May 2024Abandon4401NoNo
16980730MULTIFUNCTIONAL MOLECULES THAT BIND TO CALRETICULIN AND USES THEREOFSeptember 2020June 2024Allow4511YesNo
16994795ANTI-MICA ANTIGEN BINDING FRAGMENTS, FUSION MOLECULES, CELLS WHICH EXPRESS AND METHODS OF USINGAugust 2020August 2023Allow3611NoNo
16992497Inhibitors of the Interaction Between CLEC14A and Multimerin-2 for Inhibition of AngiogenesisAugust 2020October 2023Allow3811YesNo
16943313RECRUITING AGENT FURTHER BINDING AN MHC MOLECULEJuly 2020September 2022Allow2611NoNo
16943320METHODS AND COMPOSITIONS RELATING TO BISPECIFIC ANTI-CHI3L1 ANTIBODY REAGENTS FOR THE TREATMENT OF CANCERJuly 2020January 2023Allow3010NoNo
16940018MODIFIED NK-92 CELLS FOR TREATING CANCERJuly 2020June 2023Allow3411YesNo
16939265METHODS AND COMPOSITIONS RELATING TO ANTI-CHI3L1 ANTIBODY REAGENTS FOR THE TREATMENT OF CANCERJuly 2020January 2023Allow3010NoNo
16938576TROPHOBLAST GLYCOPROTEIN (5T4, TPBG) SPECIFIC CHIMERIC ANTIGEN RECEPTORS FOR CANCER IMMUNOTHERAPYJuly 2020January 2024Allow4220NoNo
16937285Proteins Comprising Kallikrein Related Peptidase 2 Antigen Binding Domains And Their UsesJuly 2020September 2022Allow2611YesNo
16960653COMPOSITIONS AND METHODS FOR TARGETING CLEC12A-EXPRESSING CANCERSJuly 2020January 2024Allow4211YesNo
16959619COMPOSITIONS AND METHODS FOR CANCER IMMUNOTHERAPYJuly 2020April 2024Abandon4501NoNo
16958915PRECISION MOLECULAR ADAPTOR SYSTEM FOR CAR-T IMMUNOTHERAPYJune 2020April 2024Abandon4521NoNo
16903882GENETICALLY MODIFIED NK-92 CELLS AND MONOCLONAL ANTIBOIDES FOR THE TREATMENT OF CANCERJune 2020February 2021Allow821NoNo
16879978Acceptor Framework for CDR GraftingMay 2020March 2023Abandon3401NoNo
16869322Humanized Anti-CD70 Binding Agents and Uses ThereofMay 2020September 2023Abandon4111NoNo
16862042Tetravalent Antibody-Drug Conjugates and Use ThereofApril 2020February 2021Allow1011YesNo
16755093TARGETED GENE INTEGRATION OF CRS INHIBITOR GENES FOR IMPROVED IMMUNE CELLS THERAPYApril 2020December 2024Allow5631YesNo
16845030COMPOSITIONS AND METHODS OF USE FOR AUGMENTED IMMUNE RESPONSE AND CANCER THERAPYApril 2020March 2023Abandon3501NoNo
16820504COMBINATION THERAPY OF ANTI-CD20/ANTI-CD3 BISPECIFIC ANTIBODIES AND 4-1BB (CD137) AGONISTSMarch 2020March 2023Allow3611YesNo
16645785ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLSMarch 2020June 2024Abandon5221NoNo
16498223ANTI-PD-L1/ANTI-PD-1 NATURAL ANTIBODY STRUCTURE-LIKE HETERODIMERIC BISPECIFIC ANTIBODY AND PREPARATION THEREOFFebruary 2020December 2022Allow3911YesNo
16798104NUCLEIC ACID MOLECULES ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING G-PROTEIN COUPLED RECEPTORFebruary 2020August 2023Allow4211NoNo
16798151METHODS OF TREATMENTS USING CHIMERIC ANTIGEN RECEPTORS TARGETING G-PROTEIN COUPLED RECEPTORFebruary 2020October 2020Allow810YesNo
16798059CHIMERIC ANTIGEN RECEPTORS TARGETING G-PROTEIN COUPLED RECEPTOR AND USES THEREOFFebruary 2020July 2023Allow4111YesNo
16794119METHODS OF TREATING HEMATOLOGICAL DISORDERS, SOLID TUMORS, OR INFECTIOUS DISEASES USING NATURAL KILLER CELLSFebruary 2020January 2024Abandon4721NoNo
16779011BINDING AGENTS BINDING TO PD-L1 AND CD137 AND USE THEREOFJanuary 2020December 2020Allow1011NoNo
16776349Fn14 Binding Proteins and Uses ThereofJanuary 2020March 2023Abandon3810NoNo
16752231TREATMENT USING BRUTON'S TYROSINE KINASE INHIBITORS AND IMMUNOTHERAPYJanuary 2020January 2023Abandon3601NoNo
16742434Glycan-Interacting Compounds and Methods of UseJanuary 2020March 2023Abandon3801NoNo
16733376MEANS AND METHODS FOR COUNTERACTING MYELOPROLIFERATIVE OR LYMPHOPROLIFERATIVE DISORDERSJanuary 2020November 2022Allow3511NoNo
16730778PREDICTING CANCER PROGRESSIONDecember 2019December 2023Allow4821YesNo
16728609CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODYDecember 2019February 2024Abandon4921NoNo
16718729PD-L1 ANTIBODIES BINDING CANINE PD-L1December 2019May 2022Allow2901NoNo
16704781POLYPEPTIDE-POLYNUCLEOTIDE-COMPLEX AND ITS USE IN TARGETED EFFECTOR MOIETY DELIVERYDecember 2019November 2022Allow3511YesNo
16688173ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATIONNovember 2019March 2025Abandon6041NoNo
16613343A CELL COMPRISING A CHIMERIC ANTIGEN RECEPTOR (CAR)November 2019July 2023Abandon4411NoNo
16675861CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Ra2November 2019January 2023Allow3911YesNo
16671395VACCINES WITH HIGHER CARBOHYDRATE ANTIGEN DENSITY AND NOVEL SAPONIN ADJUVANTNovember 2019September 2022Allow3511YesNo
16655646Antibodies Against Human NKG2D and Uses ThereofOctober 2019February 2022Abandon2801NoNo
16590358PGAM1 Inhibitors and Methods Related TheretoOctober 2019April 2023Abandon4311NoNo
16496144BIOMARKERS AND CAR T CELL THERAPIES WITH ENHANCED EFFICACYSeptember 2019June 2025Abandon6031NoNo
16568638CD20-BINDING IMMUNOTOXINS FOR INDUCING CELLULAR INTERNALIZATION AND METHODS USING SAMESeptember 2019April 2022Abandon3101NoNo
16546787ANTI-GPC3 ANTIBODYAugust 2019March 2020Allow721NoNo
16541847GENETICALLY MODIFIED NK-92 CELLS AND MONOCLONAL ANTIBOIDES FOR THE TREATMENT OF CANCERAugust 2019April 2020Allow811YesNo
16515870BCMA CHIMERIC ANTIGEN RECEPTORSJuly 2019October 2023Allow5131NoNo
16511600ANTI-IFNAR1 ANTIBODIES WITH REDUCED FC LIGAND AFFINITYJuly 2019May 2023Abandon4631NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner DUFFY, BRADLEY.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
7
Examiner Affirmed
4
(57.1%)
Examiner Reversed
3
(42.9%)
Reversal Percentile
64.0%
Higher than average

What This Means

With a 42.9% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
66
Allowed After Appeal Filing
16
(24.2%)
Not Allowed After Appeal Filing
50
(75.8%)
Filing Benefit Percentile
29.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 24.2% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner DUFFY, BRADLEY - Prosecution Strategy Guide

Executive Summary

Examiner DUFFY, BRADLEY works in Art Unit 1643 and has examined 878 patent applications in our dataset. With an allowance rate of 53.4%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 37 months.

Allowance Patterns

Examiner DUFFY, BRADLEY's allowance rate of 53.4% places them in the 9% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by DUFFY, BRADLEY receive 1.75 office actions before reaching final disposition. This places the examiner in the 52% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by DUFFY, BRADLEY is 37 months. This places the examiner in the 13% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +54.6% benefit to allowance rate for applications examined by DUFFY, BRADLEY. This interview benefit is in the 96% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 18.7% of applications are subsequently allowed. This success rate is in the 11% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 38.7% of cases where such amendments are filed. This entry rate is in the 51% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 66.7% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 50% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 80.6% of appeals filed. This is in the 70% percentile among all examiners. Of these withdrawals, 62.1% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 59.3% are granted (fully or in part). This grant rate is in the 76% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 6.5% of allowed cases (in the 92% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 3.4% of allowed cases (in the 73% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.