USPTO Examiner DENT ALANA HARRIS - Art Unit 1643

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17133489TREATMENT OF CD47+ DISEASE CELLS WITH SIRP ALPHA-FC FUSIONSDecember 2020March 2024Allow3911NoNo
17092043SLC45A2 PEPTIDES FOR IMMUNOTHERAPYNovember 2020June 2023Abandon3110NoNo
17026447PD-1 Peptide InhibitorsSeptember 2020December 2023Abandon3911NoNo
17017358PEPTIDES AND T CELLS FOR USE IN IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERSSeptember 2020March 2021Allow610YesNo
17017117NK CELL-DIRECTED CHIMERIC PROTEINSSeptember 2020July 2022Abandon2231NoNo
17015658PD-1 Peptide InhibitorsSeptember 2020March 2023Allow3101YesNo
16979146A METHOD OF DETECTING MAGEA4September 2020March 2024Abandon4210NoNo
17003750PLASMA MEMBRANE CITRATE TRANSPORTER FOR USE IN THE DIAGNOSIS AND TREATMENT OF CANCERAugust 2020November 2024Allow5040YesNo
16984615METHODS AND KITS FOR ANALYSIS OF HMGB1 ISOFORMSAugust 2020July 2023Abandon3611NoNo
16928293METHODS FOR DETECTING AND FOR TREATING PANCREATIC CANCERJuly 2020April 2024Allow4530YesNo
16915772NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSJune 2020October 2020Allow410YesNo
16915420METHOD OF TREATING WITH A PEPTIDEJune 2020October 2020Allow310YesNo
16899907PLASMA BIOMARKER FOR OVARIAN CANCERJune 2020May 2023Abandon3511YesNo
16900194METHODS AND COMPOSITIONS FOR ASSESSING GERMLINE RISK OF CANCERJune 2020January 2023Allow3121NoNo
16895395R-Spondin Translocations and Methods Using the SameJune 2020May 2023Abandon3501NoNo
16887765METHOD OF TREATING WITH A PEPTIDEMay 2020November 2020Allow510YesNo
16768001METHOD FOR CLASSIFYING CANCER PATIENTS INTO APPROPRIATE HEPATOCELLULAR CARCINOMA TREATMENT GROUPS AND COMPOUNDS FOR TREATING THE PATIENTMay 2020December 2024Allow5431YesNo
16814532NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSMarch 2020May 2021Allow1410NoNo
16644106METHODS FOR IDENTIFYING MYELOMA TUMOR-INITIATING CELLS AND TARGETED THERAPYMarch 2020July 2024Abandon5331YesNo
16773192INHIBITOR OF SUV39H1 HISTONE METHYLTRANSFERASE FOR USE IN CANCER COMBINATION THERAPYJanuary 2020October 2022Abandon3341YesYes
16752537COMBINATION THERAPY WITH A BET INHIBITOR, A BCL-2 INHIBITOR AND AN ANTI-CD20 ANTIBODYJanuary 2020August 2022Abandon3001NoNo
16751145METHODS OF IDENTIFYING INDIVIDUALS AT INCREASED RISK OF LUNG CANCERJanuary 2020April 2022Abandon2710NoNo
16632402METHODS AND KITS FOR PREDICTING THE SENSITIVITY OF A SUBJECT SUFFERING OF RENAL CANCER TO SUNITINIBJanuary 2020May 2023Abandon3910NoNo
16727777SHON AS A PROGNOSTIC BIOMARKER FOR CANCER AND AS A PREDICTOR OF RESPONSE TO ENDOCRINE THERAPYDecember 2019March 2025Abandon6051YesYes
16625697BIOMARKER FOR DETECTING COLORECTAL CANCERDecember 2019November 2024Abandon5931NoNo
16615423COMBINATION OF MARKERS FOR DIAGNOSING CANCERNovember 2019March 2023Allow4021NoYes
16686390IMMUNOGENIC MODULATION BY ENDOCRINE DEPRIVATION THERAPY IMPROVES SENSITIVITY OF TUMOR CELLS TO IMMUNE MEDIATED LYSISNovember 2019December 2022Abandon3711NoNo
16612485METHODS AND COMPOSITIONS OF USE OF CD8+ TUMOR INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOFNovember 2019October 2024Allow5961YesNo
16673619METHOD OF TREATING WITH A PEPTIDENovember 2019March 2020Allow410YesNo
16609721USE OF DIANHYDROGALACTITOL OR ANALOGS AND DERIVATIVES IN COMBINATION WITH VEGF INHIBITORS TO TREAT CANCEROctober 2019February 2024Abandon5250NoNo
16664543YEAST-BASED IMMUNOTHERAPY FOR CHORDOMAOctober 2019October 2022Abandon3521NoNo
16662399Anti-CD28 Humanized Antibodies Formulated for Administration to HumansOctober 2019March 2022Abandon2901NoNo
16607662DETECTION AND TARGETING OF TUMOR-PROMOTING NEUTROPHILSOctober 2019February 2023Abandon4031NoNo
16653268DIAGNOSTIC METHODS FOR LIVER DISORDERSOctober 2019January 2024Abandon5140YesNo
16494223DETECTION, QUANTIFICATION AND/OR ISOLATION OF CIRCULATING TUMOR CELLS BASED ON THE EXPRESSION OF CD321 MARKERSeptember 2019June 2024Allow5741YesNo
16563740NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSSeptember 2019February 2020Allow510NoNo
16563704NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSSeptember 2019February 2020Allow610YesNo
16558455MEST AS BIOMARKER FOR CANCER DIAGNOSIS AND PROGNOSIS AND METHOD FOR USING THEREOFSeptember 2019April 2025Abandon6041NoNo
16557234IMMUNOTHERAPY AGAINST MELANOMA AND OTHER CANCERSAugust 2019May 2023Abandon4510NoNo
16552836METHOD OF TREATING BREAST CANCERAugust 2019August 2024Allow6051YesNo
16488083ASSAY FOR DETECTION OF EARLY STAGE PANCREATIC CANCERAugust 2019February 2023Allow4221YesNo
16535855ANTI-CD22 ANTIGEN BINDING MOLECULES TO TREAT LUNG CANCER AND PROSTATE CANCERAugust 2019July 2023Abandon4730YesNo
16527770PROTECTION AGAINST STRESS-MEDIATED DAMAGE FROM IONIZING RADIATIONJuly 2019September 2021Allow2610NoNo
16523096DETECTION OF HISTONE MODIFICATION IN CELL-FREE NUCLEOSOMESJuly 2019May 2022Abandon3310NoNo
16520746PANCREATIC CANCER TARGETS AND USES THEREOFJuly 2019August 2022Abandon3711NoNo
16511935SAPOSIN-A DERIVED PEPTIDES AND USES THEREOFJuly 2019October 2022Allow3911NoNo
16503901IMMUNOTHERAPY AGAINST MELANOMA AND OTHER CANCERSJuly 2019September 2019Allow200YesNo
16503882IMMUNOTHERAPY AGAINST MELANOMA AND OTHER CANCERSJuly 2019August 2019Allow200YesNo
16446526METHOD FOR DISCRIMINATING BETWEEN PROSTATE CANCER AND A BENIGN PROSTATE DISEASEJune 2019August 2022Abandon3820NoNo
16443517RECOMBINANT POLYPEPTIDES AND METHODS OF USE THEREOFJune 2019June 2020Abandon1210NoNo
16465729METHODS AND COMPOSITIONS FOR DIAGNOSING RENAL CELL CARCINOMAMay 2019October 2022Abandon4121NoNo
16425607NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSMay 2019July 2019Allow200NoNo
16408510BINDING PROTEINS AND CHIMERIC ANTIGEN RECEPTOR T CELLS TARGETING GASP-I GRANULES AND USES THEREOFMay 2019June 2024Allow6051YesNo
16344985IMPROVEMENTS IN CD47 BLOCKADE THERAPY BY HDAC INHIBITORSApril 2019August 2023Allow5121NoYes
16387300METHOD FOR BLOCKING STRESS-INDUCED TUMOR PROGRESSIONApril 2019January 2022Allow3311YesNo
16384428METHODS OF TREATING AND PREVENTING MELANOMA WITH S-EQUOLApril 2019October 2022Abandon4221YesNo
16070828NOVEL SPECIFIC MONOCLONAL ANTIBODY TO ACETYLATED MOUSE BUBR1 AND PREPARATION METHOD THEREFORMarch 2019August 2021Allow3710YesNo
16356582ANALYSIS OF RESPONSE TO THERAPEUTICS IN CANCERMarch 2019November 2023Abandon5641NoNo
16354689CD80 EXTRACELLULAR DOMAIN POLYPEPTIDES AND THEIR USE IN CANCER TREATMENTMarch 2019April 2021Allow2500NoNo
16333590CELL DEATH BIOMARKERMarch 2019May 2023Allow5031YesNo
16331197Methods and Compositions for Treating Cancers by Inhibiting Estrogen Signaling in Myeloid-Derived Suppressor CellsMarch 2019July 2023Abandon5331NoNo
16295978CD80 EXTRACELLULAR DOMAIN POLYPEPTIDES AND THEIR USE IN CANCER TREATMENTMarch 2019February 2022Allow3511YesNo
16292054SYNTHETIC PEPTIDE, RELATIVE ARTIFICIAL ANTIGEN, RELATIVE ANTI-EHD2 ANTIBODY AND PREPARATION METHOD THEREOF AND USE THEREOFMarch 2019December 2021Allow3421YesNo
16275111METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CANCERFebruary 2019June 2022Allow4021YesNo
16271235TREATMENT OF CANCER WITH ANTI-IL-1 ALPHA ANTIBODIESFebruary 2019February 2024Abandon6020NoYes
16323807Method Relating to Evaluation of Tumor Tissue of Experimental AnimalFebruary 2019February 2022Abandon3701NoNo
16267647NOVEL PEPTIDES, COMBINATION OF PEPTIDES AS TARGETS AND FOR USE IN IMMUNOTHERAPY AGAINST GALLBLADDER CANCER AND CHOLANGIOCARCINOMA AND OTHER CANCERSFebruary 2019May 2019Allow310NoNo
16323482CAMKK2 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAMEFebruary 2019August 2024Allow6061YesNo
16256065METHODS OF INHIBITING METASTASIS IN CANCERJanuary 2019October 2021Abandon3311NoNo
16319948METHODS OF TREATEMENT OF CANCER DISEASE BY TARGETTING TUMOR ASSOCIATED MACROPHAGEJanuary 2019May 2021Abandon2801NoNo
16240474METHODS FOR TREATING COLORECTAL AND METASTATIC COLORECTAL CANCERSJanuary 2019December 2022Abandon4731YesNo
16315275VINFLUNINE AND PD1 AND/OR PDL1 INHIBITOR AS PHARMACEUTICAL COMBINATIONJanuary 2019February 2022Abandon3821YesNo
16312716METHODS AND COMPOSITIONS FOR TREATING CANCER WITH SIGLEC-9 ACTIVITY MODULATORSDecember 2018August 2021Abandon3211YesNo
16223470COMPOSITIONS AND METHODS COMPRISING DIGITAL SIGNATURES TO PREDICT RESPONSE AND RESISTANCE TO TARGETED THERAPY AND IMMUNOTHERAPYDecember 2018July 2022Allow4321YesNo
16223091SYSTEM AND METHOD FOR THE TREATMENT OF DISEASE USING A HYPERSPECIFIC MODIFIED PROTEIN SYSTEMDecember 2018May 2025Abandon6071YesNo
16207758ABT-165 IN COMBINATION WITH FOLINIC ACID, 5-FLUOROURACIL, AND IRINOTECAN FOR THE TREATMENT OF CANCERSDecember 2018September 2021Abandon3411NoNo
16306380ANTI-PD-1 ANTIBODY FOR USE IN A METHOD OF TREATING A TUMORNovember 2018August 2022Abandon4530YesNo
16301019Methods for Predicting the Usefulness of Proteins or Protein Fragments for ImmunotherapyNovember 2018July 2024Allow6061YesNo
16186245TREATMENT OF THERAPY-RESISTANT HER-2 POSITIVE BREAST CANCERNovember 2018November 2022Abandon4821NoNo
16180385DISCOVERY AND VALIDATION OF CANCER BIOMARKERS USING A PROTEIN ANALYSIS METHODOLOGY TO ANALYZE SPECIMENSNovember 2018July 2023Abandon5621NoNo
16167656Immunotherapy against melanoma and other cancersOctober 2018May 2019Allow710NoNo
16165121Immunotherapy against melanoma and other cancersOctober 2018June 2019Allow810NoNo
16165275Immunotherapy against melanoma and other cancersOctober 2018May 2019Allow710NoNo
16165116Immunotherapy against melanoma and other cancersOctober 2018June 2019Allow810NoNo
16162333IMMUNOTHERAPY AGAINST MELANOMA AND OTHER CANCERSOctober 2018January 2020Allow1530YesNo
16093180PROGNOSIS OF SEROUS OVARIAN CANCER USING BIOMARKERSOctober 2018September 2021Abandon3511NoNo
16092798COMPOSITIONS AND METHODS FOR SCREENING, MONITORING AND TREATING GASTROINTESTINAL DISEASESOctober 2018December 2021Abandon3821YesNo
16092168MACROPHAGE STIMULATION IN CD47 BLOCKADE THERAPYOctober 2018December 2022Abandon5041YesNo
16090855METHODS AND KITS FOR PREDICTING THE SENSITIVITY OF A SUBJECT SUFFERING OF RENAL CANCER TO CANCER TREATMENTOctober 2018June 2022Abandon4531YesNo
16141911ANTI-BAG3 ANTIBODIES FOR THERAPEUTIC USESeptember 2018June 2021Allow3220YesNo
16138224RECOMBINANT POLYPEPTIDES AND METHODS OF USE THEREOFSeptember 2018May 2019Allow811YesNo
16138212RECOMBINANT POLYPEPTIDES AND METHODS OF USE THEREOFSeptember 2018May 2019Allow811NoNo
16138204RECOMBINANT POLYPEPTIDES AND METHODS OF USE THEREOFSeptember 2018April 2019Allow711NoNo
16138219RECOMBINANT POLYPEPTIDES AND METHODS OF USE THEREOFSeptember 2018March 2019Allow501YesNo
16132339THERAPEUTIC COMBINATION AND METHOD FOR TREATING CANCERSeptember 2018January 2022Abandon4021NoNo
16085486Nanoliposomal Targeting of Ephrin Receptor A2 (Epha2) and Related DiagnosticsSeptember 2018February 2021Abandon2901NoNo
16118038COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL CANCERS TARGETING THE SIRPALPHA CD47 INTERACTIONAugust 2018January 2024Abandon6041NoNo
16080617THE USE OF GLUCOCORTICOID RECEPTOR MODULATORS TO POTENTIATE CHECKPOINT INHIBITORSAugust 2018February 2021Allow3040YesNo
16111894A METHOD OF TREATING AN NME7 EXPRESSING CANCER WITH A PEPTIDEAugust 2018April 2023Allow5541YesYes
16111862ANTI-NME ANTIBODYAugust 2018November 2022Abandon5031NoYes

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner DENT, ALANA HARRIS.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
22
Examiner Affirmed
10
(45.5%)
Examiner Reversed
12
(54.5%)
Reversal Percentile
80.9%
Higher than average

What This Means

With a 54.5% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
146
Allowed After Appeal Filing
39
(26.7%)
Not Allowed After Appeal Filing
107
(73.3%)
Filing Benefit Percentile
40.0%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 26.7% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner DENT, ALANA HARRIS - Prosecution Strategy Guide

Executive Summary

Examiner DENT, ALANA HARRIS works in Art Unit 1643 and has examined 884 patent applications in our dataset. With an allowance rate of 40.5%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 41 months.

Allowance Patterns

Examiner DENT, ALANA HARRIS's allowance rate of 40.5% places them in the 8% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by DENT, ALANA HARRIS receive 2.32 office actions before reaching final disposition. This places the examiner in the 61% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by DENT, ALANA HARRIS is 41 months. This places the examiner in the 20% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +40.6% benefit to allowance rate for applications examined by DENT, ALANA HARRIS. This interview benefit is in the 87% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 13.5% of applications are subsequently allowed. This success rate is in the 10% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 32.5% of cases where such amendments are filed. This entry rate is in the 49% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 55.6% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 48% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 75.0% of appeals filed. This is in the 63% percentile among all examiners. Of these withdrawals, 54.5% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 72.9% are granted (fully or in part). This grant rate is in the 78% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 2.9% of allowed cases (in the 80% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 2.8% of allowed cases (in the 75% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.