USPTO Examiner PUTTLITZ KARL J - Art Unit 1642

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17133388CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODSDecember 2020April 2024Allow4040YesNo
17128241NEUTRALIZATION OF INHIBITORY PATHWAYS IN LYMPHOCYTESDecember 2020September 2023Abandon3320NoNo
17127697COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD79b ANTIBODY-DRUG CONJUGATEDecember 2020October 2023Abandon3420NoNo
17124972B7-H3 DIRECTED ANTIBODY DRUG CONJUGATESDecember 2020September 2022Allow2100YesNo
17251147CONJUGATES WITH INTERNAL AND TERMINAL-END HEPAROSAN LINKAGESDecember 2020April 2024Abandon4010NoNo
15734116COMPOSITIONS AND METHODS FOR TARGETED IMMUNOTHERAPYDecember 2020April 2024Abandon4110NoNo
17105402ANTI-CD71 ACTIVATABLE ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOFNovember 2020October 2021Abandon1010YesNo
17103866COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD117+ CELLSNovember 2020August 2023Allow3310YesYes
17057486MOLECULAR ADJUVANTNovember 2020June 2024Abandon4301NoNo
16950522ANTI-CD117 ANTIBODIES AND CONJUGATESNovember 2020September 2022Allow2200YesNo
17089227Saccharide Derivative of a Toxic Payload and Antibody Conjugates ThereofNovember 2020August 2023Abandon3301NoNo
17078467THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOFOctober 2020December 2022Allow2600YesNo
17074387SITE-SPECIFIC QUANTITATION OF DRUG CONJUGATIONSOctober 2020May 2023Allow3111NoNo
17036138COMPOSITIONS AND METHODS FOR TREATING LYSOSOMAL DISORDERSSeptember 2020February 2024Allow4111YesNo
17037370Drug-Conjugates With a Targeting Molecule and Two Different DrugsSeptember 2020January 2024Allow3920NoYes
17006926IMMUNOMODULATING TREATMENTS OF BODY CAVITIESAugust 2020March 2023Abandon3010NoNo
17006954COMPOSITIONS, ARTICLES OF MANUFACTURE AND METHODS FOR TREATING CANCERAugust 2020March 2023Abandon3010NoNo
17006881CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODSAugust 2020July 2024Abandon4701NoNo
16996780FORMULATIONS OF TESTOSTERONE AND METHODS OF TREATMENT THEREWITHAugust 2020August 2023Allow3520NoNo
16992453Anti-STEAP2 Antibodies, Antibody-Drug Conjugates, and Bispecific Antigen-Binding Molecules that Bind STEAP2 and CD3, and Uses ThereofAugust 2020December 2022Allow2800YesNo
16990330ANTI-GPR20 ANTIBODY AND ANTI-GPR20 ANTIBODY-DRUG CONJUGATEAugust 2020September 2020Allow100YesNo
16945069GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOFJuly 2020February 2023Abandon3010NoNo
16934955ACTIVATABLE ANTI-CD166 ANTIBODIES AND METHODS OF USE THEREOFJuly 2020November 2023Abandon4020NoNo
16958463PRO-CYCLIC DINUCLEOTIDES AND PRO-CYCLIC DINUCLEOTIDE CONJUGATES FOR CYTOKINE INDUCTIONJune 2020April 2023Allow3321NoNo
16914112ANTI-CD8 ANTIBODIES AND USES THEREOFJune 2020July 2022Allow2500YesNo
16910921INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODSJune 2020March 2023Abandon3220NoNo
15733309ONE-POT PROCESS FOR PREPARING INTERMEDIATE OF ANTIBODY-DRUG CONJUGATEJune 2020May 2023Allow3420YesYes
16906985LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDSJune 2020December 2022Allow3010NoNo
16955477COMBINATION OF AN ANTI-PD-L1 ANTIBODY AND IDO1 INHIBITOR FOR THE TREATMENT OF CANCERJune 2020September 2023Abandon3911NoNo
16896930MUTANT ANTIBODIES AND CONJUGATION THEREOFJune 2020May 2023Allow3501YesNo
16771124GENERATION-DEPENDENT SUPRAMOLECULAR ASSEMBLIES OF PROTEIN-DENDRON CONJUGATESJune 2020May 2023Allow3522YesNo
16894602ENEDIYNE CONJUGATESJune 2020August 2022Allow2710YesNo
16769993INTRACELLULAR DELIVERY OF BIOMOLECULES TO MODULATE ANTIBODY PRODUCTIONJune 2020October 2023Abandon4121NoNo
16892529CD48 ANTIBODIES AND CONJUGATES THEREOFJune 2020December 2022Abandon3110NoNo
16892467Methods of Treating or Preventing an Attention Disorder, Cognitive Disorder, and/or Dementia Associated with a Neurodegenerative DisorderJune 2020April 2023Allow3511NoNo
16767804FUSION PROTEIN COMPRISING GLUTATHIONE-S-TRANSFERASE AND PROTEIN HAVING BINDING AFFINITY TARGET CELL OR TARGET PROTEIN, AND USE THEREOFMay 2020July 2023Allow3820YesNo
16763814PYRROLOBENZODIAZEPINE CONJUGATESMay 2020September 2022Allow2800YesNo
16763776MULTIFUNCTIONAL IMMUNE CELL THERAPIESMay 2020March 2023Allow3401YesNo
16870853COMBINATION THERAPY WITH NOTCH AND PD-1 OR PD-L1 INHIBITORSMay 2020July 2023Allow3840NoNo
16868365METHODS FOR TREATING HYPERSOMNIAMay 2020December 2022Abandon3110NoNo
16867412METHOD OF TREATING HAND-FOOT SYNDROME AND SYMPTOMS ASSOCIATED THEREWITHMay 2020September 2023Abandon4020YesNo
16853619COMPOSITIONS AND METHODS FOR THE DEPLETION OF CELLSApril 2020November 2023Abandon4302NoNo
16849311Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate FormulationsApril 2020May 2024Allow4931NoNo
16311084KILLER CELL CAPABLE OF EFFICIENTLY AND STABLY EXPRESSING ANTIBODY, AND USES THEREOFMarch 2020March 2024Allow6013YesNo
16828279ANTIBODY-DRUG CONJUGATEMarch 2020December 2022Allow3210NoNo
16650226ANTIBODY-DRUG CONJUGATES AND USES THEREOFMarch 2020November 2022Allow3111YesNo
16649083THERAPEUTIC AGENTS SPECIFICALLY DELIVERED BY EXOSOMES FOR CANCER TREATMENTMarch 2020August 2022Allow2910NoNo
16803931CENICRIVIROC COMBINATION THERAPY FOR THE TREATMENT OF FIBROSISFebruary 2020July 2023Abandon4011NoNo
16642277NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATEFebruary 2020December 2021Allow2210NoNo
16796422NK-3 RECEPTOR ANTAGONISTS FOR THERAPEUTIC TREATMENT OF LEPTIN-RELATED DISEASEFebruary 2020June 2022Allow2800YesNo
16793843CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOFFebruary 2020April 2022Allow2600YesNo
16784069HUMANIZED ANTIBODIES TO LIV-1 AND USE OF SAME TO TREAT CANCERFebruary 2020September 2023Abandon4311NoNo
16777513Use of Ureidomustine (BO-1055) in Cancer TreatmentJanuary 2020October 2022Abandon3210NoNo
16776395SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOFJanuary 2020September 2022Allow3210YesNo
16774829POLYMER LINKERS AND THEIR USESJanuary 2020August 2022Allow3010YesNo
16740570Use of Paeoniflorin-6'-O-benzenesulfonate in treatment of Sj�gren's syndromeJanuary 2020November 2023Abandon4640NoNo
167400236-SUBSTITUTED AND 7-SUBSTITUTED MORPHINAN ANALOGS AND THE USE THEREOFJanuary 2020September 2023Abandon4421NoNo
16740312BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USESJanuary 2020January 2022Allow2400YesNo
16629046CHIMERIC ANTIGEN RECEPTORS WITH MUTATED CD28 COSTIMULATORY DOMAINSJanuary 2020May 2024Allow5222YesYes
16696455PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOFNovember 2019February 2023Allow3911YesNo
16695239TETRAZOLONE-SUBSTITUTED DIHYDROPYRIDINONE MGAT2 INHIBITORSNovember 2019June 2022Allow3110NoNo
16689286PYRROLOBENZODIAZEPINE PRODRUGS AND ANTIBODY CONJUGATES THEREOFNovember 2019October 2022Allow3511NoNo
16684130NOVEL ANTI-HUMAN MUC1 ANTIBODY FAB FRAGMENTNovember 2019July 2022Abandon3210NoNo
16683667CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTSNovember 2019January 2022Allow2600YesNo
16681306NOVEL ANTI-HUMAN MUC1 ANTIBODY FAB FRAGMENTNovember 2019October 2022Allow3520NoNo
16679379METHOD OF TREATING COCAINE ADDICTIONNovember 2019February 2022Allow2710NoNo
16674381METHOD OF TREATING POST-TRAUMATIC STRESS DISORDERNovember 2019July 2023Allow4501YesNo
16484290NON-PEPTIDIC POLYMERIC LINKER COMPOUND, CONJUGATE COMPRISING SAME LINKER COMPOUND, AND METHODS FOR PREPARING SAME LINKER COMPOUND AND CONJUGATEOctober 2019November 2023Allow5111NoNo
16658245MODULATORS OF RESISTANT ANDROGEN RECEPTOROctober 2019April 2023Allow4211YesNo
16656273Methods of Reducing Mammographic Breast Density and/or Breast Cancer RiskOctober 2019June 2022Abandon3210NoNo
16605710COMBINATION THERAPY WITH AN ANTI-PSMA ANTIBODY-DRUG CONJUGATEOctober 2019April 2022Abandon3010NoNo
16605708COMBINATION THERAPY WITH AN ANTI-CD25 ANTIBODY-DRUG CONJUGATEOctober 2019July 2022Allow3310NoNo
16605238MODIFIED CYTOMEGALOVIRUS PROTEINS AND STABILIZED COMPLEXESOctober 2019June 2024Abandon5611NoNo
16594728ANTI-HER2 BIPARATOPIC ANTIBODY-DRUG CONJUGATES AND METHODS OF USEOctober 2019February 2021Allow1620YesNo
16590967COMBINATION THERAPY USING ANTI-SSEA-4 ANTIBODY IN COMBINATION WITH THERAPEUTIC ONCOLOGY AGENTSOctober 2019March 2024Abandon5340NoNo
16587720DELTA-OPIOID RECEPTOR TARGETED AGENT FOR MOLECULAR IMAGING AND IMMUNOTHERAPY OF CANCERSeptember 2019June 2022Abandon3210NoNo
16586546CYCLOPHOSPHAMIDE ANALOGS FOR USE AS IMMUNOGENS AND ASSAY CONJUGATES FOR AN IMMUNOASSAY OF CYCLOPHOSPHAMIDE AND IFOSFAMIDESeptember 2019April 2022Allow3010YesNo
16584272BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2September 2019May 2022Abandon3210NoNo
16582295DOCETAXEL ALBUMIN NANOPARTICLE PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOFSeptember 2019April 2022Allow3110YesNo
16580178COMBINATION OF IMMUNOTHERAPEUTICS AND BISFLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS FOR TREATING LYMPHOMASSeptember 2019November 2022Abandon3821NoNo
16580505PHARMACEUTICAL COMBINATIONSSeptember 2019February 2022Allow2910NoNo
16576395COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF SCHISTOSOMIASISSeptember 2019February 2023Abandon4020NoNo
16574500AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASESeptember 2019November 2019Allow200YesNo
16491875CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAMESeptember 2019August 2022Abandon3510NoNo
16563507BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the SameSeptember 2019June 2022Abandon3310NoNo
16489455COMPOSITIONS AND METHODS FOR CAR T CELL THERAPYAugust 2019July 2023Allow4721YesNo
16487419THERAPEUTIC COMPOSITIONS AND RELATED METHODS FOR PHOTOIMMUNOTHERAPYAugust 2019March 2023Abandon4330YesNo
165372443-ALKYL PYRIDINIUM COMPOUND FROM RED SEA SPONGE WITH POTENT ANTIVIRAL ACTIVITYAugust 2019August 2022Abandon3641YesNo
16534903BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOFAugust 2019March 2023Abandon4311NoNo
16482836DOSING SCHEDULE OF A WNT INHIBITOR AND AN ANTI-PD-1 ANTIBODY MOLECULE IN COMBINATIONAugust 2019March 2022Allow3220NoNo
16475809COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONSJuly 2019January 2024Abandon5410NoNo
16456177DUOCARMYCIN ADCS SHOWING IMPROVED IN VIVO ANTITUMOR ACTIVITYJune 2019May 2022Allow3420NoYes
16470950AMANITIN ANTIBODY CONJUGATESJune 2019February 2022Allow3210NoNo
16469768HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOFJune 2019September 2021Allow2711YesNo
16437624Diagnostic System and Process for Rapid Bacterial Infection DiagnosisJune 2019March 2020Abandon910NoNo
16467450CYSTEINE PEPTIDE-ENABLED ANTIBODIESJune 2019March 2024Abandon5731NoNo
16432244PRESERVATION OF IMMUNE RESPONSE DURING CHEMOTHERAPY REGIMENSJune 2019August 2022Allow3811NoNo
16423976NEUROACTIVE STEROID SOLUTIONS AND THEIR METHODS OF USEMay 2019January 2023Abandon4320NoNo
16419971ANTIPROLIFERATIVE COMPOUNDS AND BISPECIFIC ANTIBODY AGAINST BCMA AND CD3 FOR COMBINED USEMay 2019April 2022Allow3520NoNo
16414895NOVEL ANTI-HUMAN MUC1 ANTIBODY FAB FRAGMENTMay 2019August 2019Allow301YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner PUTTLITZ, KARL J.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
3
Examiner Affirmed
1
(33.3%)
Examiner Reversed
2
(66.7%)
Reversal Percentile
85.4%
Higher than average

What This Means

With a 66.7% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
34
Allowed After Appeal Filing
8
(23.5%)
Not Allowed After Appeal Filing
26
(76.5%)
Filing Benefit Percentile
32.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 23.5% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner PUTTLITZ, KARL J - Prosecution Strategy Guide

Executive Summary

Examiner PUTTLITZ, KARL J works in Art Unit 1642 and has examined 375 patent applications in our dataset. With an allowance rate of 61.3%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 32 months.

Allowance Patterns

Examiner PUTTLITZ, KARL J's allowance rate of 61.3% places them in the 23% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by PUTTLITZ, KARL J receive 2.20 office actions before reaching final disposition. This places the examiner in the 56% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by PUTTLITZ, KARL J is 32 months. This places the examiner in the 49% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +43.4% benefit to allowance rate for applications examined by PUTTLITZ, KARL J. This interview benefit is in the 89% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 20.5% of applications are subsequently allowed. This success rate is in the 25% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 27.1% of cases where such amendments are filed. This entry rate is in the 39% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 46.2% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 42% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 87.5% of appeals filed. This is in the 80% percentile among all examiners. Of these withdrawals, 71.4% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 59.8% are granted (fully or in part). This grant rate is in the 61% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 5.2% of allowed cases (in the 83% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.