USPTO Examiner LU CHENG - Art Unit 1642

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17254433COMPOSITIONS AND METHODS FOR PROTEIN LABELING, MODIFICATION, ANALYSIS, AND TARGETED DELIVERYDecember 2020September 2024Allow4511YesNo
17252035COMPOSITION FOR DIAGNOSIS OF BONE METASTASIS OF CANCER AND KIT COMPRISING SAMEDecember 2020March 2025Abandon5130NoNo
16972404INHIBITORS OF SHP2December 2020June 2024Abandon4301NoNo
17059995PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING CD300C EXPRESSION INHIBITOR OR ACTIVITY INHIBITORNovember 2020November 2024Abandon4831YesNo
17099547USE OF ANTI-PD-1 ANTIBODY IN COMBINATION WITH ANTI-CD27 ANTIBODY IN CANCER TREATMENTNovember 2020December 2023Allow3711NoNo
17084751ANTI-CD19 THERAPY IN COMBINATION WITH LENALIDOMIDE FOR THE TREATMENT OF LEUKEMIA OR LYMPHOMAOctober 2020September 2024Abandon4740NoNo
17051018FERROCHELATASE INHIBITORS AND METHODS OF USEOctober 2020July 2024Allow4521YesNo
17050832HLA-J AND MEDICAL/DIAGNOSTIC USES THEREOFOctober 2020November 2023Abandon3611NoNo
17050620HIGH AFFINITY MONOCLONAL ANTIBODIES (MABS) AGAINST CELL SURFACE EXPRESSED HUMAN CARBONIC ANHYDRASE IX (HCA-IX), AND USES THEREOFOctober 2020January 2025Allow5121NoNo
17076569METHODS OF TREATING HER2-POSITIVE CANCEROctober 2020December 2023Abandon3701NoNo
17074021METHODS OF INACTIVATING GENE EDITING MACHINERIESOctober 2020April 2025Abandon5421NoNo
17047057METHODS OF CANCER TREATMENT USING TUMOR ANTIGEN-SPECIFIC T CELLSOctober 2020September 2021Allow1110YesNo
17046719METHOD OF MONITORING RESPONSE TO A TREATMENTOctober 2020May 2024Abandon4310NoNo
17063617COMPOSITIONS AND METHODS FOR MODULATING AND DETECTING TISSUE SPECIFIC TH17 CELL PATHOGENICITYOctober 2020September 2024Allow4731YesNo
17040380ANTI-CD137 ANTIBODIES FOR COMBINATION WITH ANTI-PD-L1 ANTIBODIESSeptember 2020March 2024Allow4130YesNo
16982476PERIOSTIN ANTIBODIES AND METHODS OF USING THE SAMESeptember 2020December 2024Allow5121YesNo
16980659BISPECIFIC ANTIBODIES TO MOSPD2 AND T CELL- OR NK CELL-SPECIFIC MOLECULESSeptember 2020January 2023Abandon2811NoNo
16979935ANTI-CD25 FOR TUMOUR SPECIFIC CELL DEPLETIONSeptember 2020February 2023Allow2920YesNo
16993950NIR-CONJUGATED TUMOR-SPECIFIC ANTIBODIES AND USES THEREOFAugust 2020May 2023Abandon3331NoNo
16969119ANTI-HER2 ANTIBODIESAugust 2020November 2023Allow3911YesNo
16969189IgG EPITOPE AND APPLICATIONS THEREOF AS A DRUG TARGETAugust 2020April 2024Allow4441YesNo
16966081ANTI-CD47 ANTIBODY AND USE THEREOFJuly 2020December 2022Allow2910YesNo
16940019ANTIBODIES FOR EPIDERMAL GROWTH FACTOR RECEPTOR 3 (HER3)July 2020October 2023Abandon3801NoNo
16925818ANTIGEN BINDING MOLECULES TO TIGITJuly 2020July 2023Abandon3721NoNo
16956340ENZYME-MEDIATED DEPLETION OF ADENOSINE AND/OR METHYLTHIOADENOSINEJune 2020January 2023Abandon3111YesNo
16956381PREDICTIVE BIOMARKERS FOR TREATMENT OF EYE DISEASESJune 2020April 2023Abandon3401NoNo
16772306Methods and Combination Therapy to Treat CancerJune 2020December 2022Abandon3011NoNo
16771802BIOMARKERS PREDICTIVE OF ANTI-IMMUNE CHECKPOINT RESPONSEJune 2020August 2023Allow3821YesNo
16890155HLA-G Specific Chimeric Antigen Receptor, Nucleic Acid, HLA-G Specific Chimeric Antigen Receptor Expression Plasmid, HLA-G Specific Chimeric Antigen Receptor Expressing Cell, Use Thereof, And Pharmaceutical Composition For Treating CancerJune 2020July 2022Allow2510NoNo
16768838COMBINATION THERAPY WITH ANTI-IL-8 ANTIBODIES AND ANTI-PD-1 ANTIBODIES FOR TREATING CANCERJune 2020December 2022Allow3021NoNo
16768578ENHANCING T-CELL FUNCTION AND TREATING A T-CELL DYSFUNCTIONAL DISORDER WITH A COMBINATION OF AN LSD INHIBITOR AND A PD-1 BINDING ANTAGONISTMay 2020March 2023Abandon3411NoNo
16886559METHODS OF TREATING CANCERMay 2020December 2022Allow3011YesNo
16879636Engineered Expression of Cell Surface and Secreted Sialidase by CAR T Cells for Increased Efficacy in Solid TumorsMay 2020June 2024Abandon4821NoNo
16764664TRANSFORMED HUMAN CELL AND USE THEREOFMay 2020January 2023Abandon3201NoNo
16763867GP96-BASED CANCER THERAPYMay 2020December 2023Abandon4340NoNo
16761848CANCER BIOMARKERS AND METHODS OF USE THEREOFMay 2020November 2022Abandon3011NoNo
16760776IMMUNOSTIMULATORY AGONISTIC ANTIBODIES FOR USE IN TREATING CANCERApril 2020October 2022Allow3021YesNo
16759371TUMOR SPECIFIC ANTIBODIES AND T-CELL RECEPTORS AND METHODS OF IDENTIFYING THE SAMEApril 2020August 2023Allow4021NoNo
16754852HUMAN PD-L1 ANTIBODIES AND METHODS OF USE THEREFORApril 2020July 2022Allow2810YesNo
16625936Anti-Tumor Immunotherapy EnhancerApril 2020April 2023Allow4021YesNo
16652079ANTI-CD146 ANTIBODIES AND USES THEREOFMarch 2020April 2022Allow2510YesNo
16651959CARS AND BISPECIFIC ANTIBODIES FOR TREATMENT OF MANTLE CELL LYMPHOMAMarch 2020May 2023Allow3810YesNo
16648428CLAUDIN6 ANTIBODIES AND METHODS OF TREATING CANCERMarch 2020October 2022Abandon3101NoNo
16645237CONDITIONALLY ACTIVATED BINDING MOIETIES CONTAINING Fc REGIONSMarch 2020October 2021Abandon2001NoNo
16784021OBINUTUZUMAB TREATMENT OF A DLBCL PATIENT SUBGROUPFebruary 2020October 2022Allow3311YesNo
16636741HSP70 BASED COMBINATION THERAPYFebruary 2020May 2024Allow5241YesYes
16777345HERCEPTIN� ADJUVANT THERAPYJanuary 2020June 2022Abandon2810NoNo
16738535RECOMBINANT VACCINIA VIRUS AND METHODS OF USE THEREOFJanuary 2020August 2022Allow3111YesNo
16625362COMBINATION THERAPIES COMPRISING TARGETED THERAPEUTICSDecember 2019January 2023Abandon3711NoNo
16620694COMBINATION THERAPY WITH ICOS AGONIST AND OX40 AGONIST TO TREAT CANCERDecember 2019April 2022Abandon2810NoNo
16617487CHIMERIC ANTIGEN RECEPTORS TARGETING FLT3November 2019September 2024Allow5821YesNo
16616548LYMPHOCYTE ANTIGEN CD5-LIKE (CD5L) MONOMER, HOMODIMER, AND INTERLEUKIN 12B (P40) HETERODIMER AGONISTS AND METHODS OF USE THEREOFNovember 2019May 2022Abandon3001NoNo
16615112ANTI-PD-L1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOFNovember 2019December 2022Allow3730YesNo
16614237COMBINATION OF AN ERBB-2/ERBB-3 BISPECIFIC ANTIBODY WITH ENDOCRINE THERAPY FOR BREAST CANCERNovember 2019November 2024Allow6041YesYes
16679272METHOD FOR TREATING ANTI-HER2 THERAPY-RESISTANT MUC4+ HER2+ CANCERNovember 2019January 2022Abandon2720NoNo
16610868ANTIBODY VARIABLE DOMAINS AND ANTIBODY CONSTRUCTSNovember 2019September 2022Allow3520NoNo
16610401IMMUNOTHERAPEUTIC TUMOR TREATMENT METHODNovember 2019March 2024Allow5241NoNo
16658047COMBINATION IMMUNOTHERAPY FOR TREATMENT OF TRIPLE-NEGATIVE BREAST CANCEROctober 2019September 2022Allow3520YesNo
16657828ABITUZUMAB FOR THE TREATMENT OF COLORECTAL CANCEROctober 2019August 2024Allow5841YesNo
16500051NK CELL-ACTIVATING FUSION PROTEIN, NK CELL, AND PHARMACEUTICAL COMPOSITION INCLUDING SAMEOctober 2019January 2023Allow3920YesNo
16499393COMPOSITIONS AND METHODS FOR TREATING OVARIAN TUMORSSeptember 2019December 2023Allow5031YesNo
16499623COMPOSITIONS AND METHODS FOR TARGETING AND KILLING ALPHA-V BETA-3-POSITIVE CANCER STEM CELLS (CSCS) AND TREATING DRUG RESISTANT CANCERSSeptember 2019April 2024Abandon5550YesNo
16498505ANTIBODY BINDING SPECIFICALLY TO N-TERMINAL REGION OF LYSYL-TRNA SYNTHETASE EXPOSED ON CELL MEMBRANESeptember 2019February 2023Allow4121YesNo
16499095BIOMARKERS FOR CANCER THERAPEUTICSSeptember 2019April 2024Allow5531NoYes
16498577COMPOSITIONS AND METHODS FOR TREATING LUNG CANCERSeptember 2019November 2022Allow3711YesNo
16497937Compositions and Methods for the Treatment of CancerSeptember 2019March 2022Abandon2910NoNo
16495874PRODUCTION OF RNA BY YEASTS WITH RECOMBINANT PSEUDO-VIRAL PARTICLESSeptember 2019January 2024Allow5221YesNo
16576734THERAPEUTIC APOPTOTIC CELLS FOR CANCER THERAPYSeptember 2019December 2023Allow5151YesNo
16494102METHOD FOR THE TREATMENT OF PATIENTS WITH CARCINOMASSeptember 2019February 2024Allow5360YesNo
16489088Dosing schedule for a combination of Ceritinib and an anti-PD-1 antibody moleculeAugust 2019November 2021Abandon2710YesNo
16488025BISPECIFIC BINDING MOLECULES THAT ARE CAPABLE OF BINDING CD137 AND TUMOR ANTIGENS, AND USES THEREOFAugust 2019May 2022Allow3331YesNo
16487272FREQUENT EGFR AND NTRK SOMATIC MUTATIONS IN COLORECTAL CANCER (CRC) WITH MICROSATELLITE INSTABILITY (MSI)August 2019May 2024Allow5721YesNo
16486741CO-USE OF ANTI-BCMA ANTIBODY AND ANTIBODY-COUPLED T CELL RECEPTOR (ACTR) IN CANCER THERAPY AND B CELL DISORDERSAugust 2019December 2021Abandon2801NoNo
16486688ANTI-PD-1 ANTIBODIES FOR TREATMENT OF LUNG CANCERAugust 2019November 2021Allow2710YesNo
16486150ANTI-PROGRAMMED DEATH-LIGAND 1 (PD-L1) ANTIBODIES AND THERAPEUTIC USES THEREOFAugust 2019January 2022Allow2920YesNo
16485039METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCERS ASSOCIATED WITH ACTIVATION OF THE MAPK PATHWAYAugust 2019June 2022Allow3430YesNo
16535075RECOMBINANT BIFUNCTIONAL PROTEIN TARGETING CD47 AND HER2August 2019May 2022Allow3321YesNo
16483943METHODS FOR PREDICTING RESPONSIVENESS OF A CANCER TO AN IMMUNOTHERAPEUTIC AGENT AND METHODS OF TREATING CANCERAugust 2019September 2022Allow3821YesNo
16482048INHIBITORS OF EPHRIN B1 FOR TUMOR TREATMENTJuly 2019June 2022Allow3421YesNo
16482163METHOD OF INDIRECT IMMUNIZATION OF HUMAN OVARIAN CANCER PATIENTS THROUGH SELECTION OF XENOGENEIC IMMUNOGLOBULIN FC PORTIONSJuly 2019October 2021Abandon2610NoNo
16526694BIOMARKERS FOR DISEASE PROGRESSION IN MELANOMAJuly 2019October 2021Abandon2710NoNo
16479143Combinations of Cabozantinib and Atezolizumab to Treat CancerJuly 2019August 2021Allow2510NoNo
16516223NOVEL ANTIBODIES AND METHODS FOR MAKING AND USING THE SAMEJuly 2019June 2022Allow3521YesNo
16475770ERBB2 ANTIBODIES AND USES THEREFOREJuly 2019February 2022Allow3211YesNo
16457045MULTIFUNCTIONAL PROTEIN MOLECULES COMPRISING DECORIN AND USE THEREOFJune 2019February 2022Allow3211YesNo
16473576T-CELL MODULATORY MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOFJune 2019August 2023Allow5021YesNo
16447067Methods for Treating Cancer with Bispecific Anti-CD3xMUC16 Antibodies and Anti-PD-1 AntibodiesJune 2019October 2021Allow2820YesNo
16434232AMHRII-BINDING COMPOUNDS FOR PREVENTING OR TREATING CANCERSJune 2019February 2022Abandon3211NoNo
16465601COMBINATION THERAPYMay 2019February 2022Abandon3311NoNo
16465349COMBINATION THERAPYMay 2019November 2022Abandon4221NoNo
16417889MONOSPECIFIC AND MULTISPECIFC ANTI-TMEFF2 ANTIBODIES AND THEIR USESMay 2019May 2023Allow4741NoNo
16417863ANTIBODIES SPECIFIC FOR GUCY2C AND USES THEREOFMay 2019July 2022Allow3811YesNo
16348135ANTI-CD46 ANTIBODIES AND METHODS OF USEMay 2019April 2022Allow3521YesNo
16347397IMMUNE MODULATORS FOR REDUCING IMMUNE-RESISTANCE IN MELANOMA AND OTHER PROLIFERATIVE DISEASESMay 2019August 2024Abandon6051YesYes
16347005BETA-ALETHINE, IMMUNE MODULATORS, AND USES THEREOFMay 2019February 2023Allow4531YesNo
16345422BIOMARKERS AND TREATMENTS FOR METASTATIC CANCERApril 2019June 2022Abandon3721NoNo
16380493ANTI-PD-L1 ANTIBODIES AND VARIANTSApril 2019October 2021Allow3011YesNo
16371589THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCERApril 2019September 2021Allow2911YesNo
16333993THE NOVEL MONOCLONAL ANTIBODIES TO PROGRAMMED DEATH 1 (PD-1)March 2019March 2022Allow3621YesNo
16331786FUSION PROTEIN AND APPLICATIONS THEREOFMarch 2019May 2023Abandon5131NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner LU, CHENG.

Strategic Value of Filing an Appeal

Total Appeal Filings
4
Allowed After Appeal Filing
0
(0.0%)
Not Allowed After Appeal Filing
4
(100.0%)
Filing Benefit Percentile
0.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 0.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner LU, CHENG - Prosecution Strategy Guide

Executive Summary

Examiner LU, CHENG works in Art Unit 1642 and has examined 123 patent applications in our dataset. With an allowance rate of 60.2%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 37 months.

Allowance Patterns

Examiner LU, CHENG's allowance rate of 60.2% places them in the 22% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by LU, CHENG receive 1.91 office actions before reaching final disposition. This places the examiner in the 43% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by LU, CHENG is 37 months. This places the examiner in the 31% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +69.6% benefit to allowance rate for applications examined by LU, CHENG. This interview benefit is in the 98% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 29.6% of applications are subsequently allowed. This success rate is in the 59% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 51.1% of cases where such amendments are filed. This entry rate is in the 78% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 86% percentile among all examiners. Of these withdrawals, 66.7% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 129.4% are granted (fully or in part). This grant rate is in the 95% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 2% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 21.6% of allowed cases (in the 95% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.