USPTO Examiner ALLEN MICHAEL D - Art Unit 1642

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18738887Cancer TreatmentsJune 2024November 2025Abandon1811NoNo
18429111[3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUNDJanuary 2024June 2025Abandon1621NoNo
18538242ANTIGEN BINDING PROTEINS SPECIFICALLY BINDING MAGE-ADecember 2023December 2024Allow1221YesNo
18498843ENGINEERED SIRPa VARIANTS AND METHODS OF USE THEREOFOctober 2023December 2024Allow1341YesNo
18368138[3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUNDSeptember 2023October 2024Abandon1311NoNo
18244135BISPECIFIC ANTIBODY MOLECULES BINDING TO CD3 AND EGFRvIIISeptember 2023July 2025Allow2240YesNo
18341688ANTI-TCR ANTIBODY MOLECULES AND USES THEREOFJune 2023September 2025Allow2741YesNo
18309488USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMABApril 2023October 2024Abandon1821NoNo
18183878IMMUNITY ENHANCING AGENT FOR CANCER BY ALLERGIN-1 ANTAGONISTMarch 2023June 2025Abandon2701NoNo
18177594PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSMarch 2023November 2025Abandon3311NoNo
18176072NOVEL DDR1 ANTIBODIES AND USES THEREOFFebruary 2023March 2025Allow2421YesNo
18174892ENHANCING ANTI-CANCER ACTIVITY OF IMMUNOMODULATORY FC FUSION PROTEINSFebruary 2023May 2025Abandon2710NoNo
18168930CLINICAL ASSESSMENT OF M-PROTEIN RESPONSE IN MULTIPLE MYELOMAFebruary 2023March 2025Abandon2520YesNo
18163659ANTI-MESOTHELIN ANTIGEN-BINDING MOLECULES AND USES THEREOFFebruary 2023September 2023Allow811YesNo
18163015CANCER TREATMENTSFebruary 2023October 2024Abandon2021NoNo
18161070ANTIBODIES TARGETING THE B-CELL RECEPTOR OF CHRONIC LYMPHOCYTIC LEUKEMIA AND USES THEREOFJanuary 2023January 2024Allow1120YesNo
18157597THERAPEUTIC, DIAGNOSTIC, AND PROGNOSTIC METHODS FOR CANCERJanuary 2023October 2023Abandon900NoNo
18153181ANTIBODY MOLECULES WHICH BIND CD45January 2023June 2024Abandon1701NoNo
18002832ANTI-NME ANTIBODY AND METHOD OF TREATING CANCER OR CANCER METASTASISDecember 2022August 2025Abandon3241YesNo
18052264METHODS FOR MONITORING AND TREATING CANCERNovember 2022August 2025Abandon3330NoNo
18049434MIC Antibodies and Binding Agents and Methods of Using the SameOctober 2022February 2024Allow1621NoNo
17946158Anti-TIGIT AntibodiesSeptember 2022October 2024Abandon2521NoNo
17815367Therapeutic Use of Antibodies Against ENPP3July 2022July 2023Allow1121YesNo
17849016PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSJune 2022January 2023Allow710NoNo
17807465Method of treating solid cancers and/or metastases thereof, medicaments therefore, and a method of predicting the clinical outcome of treating solid cancers and/or metastases thereofJune 2022January 2025Abandon3120YesNo
17825202RECOMBINANT MONOVALENT ANTIBODIES AND METHODS FOR PRODUCTION THEREOFMay 2022November 2024Abandon3001NoNo
17743230THERAPEUTIC, DIAGNOSTIC, AND PROGNOSTIC METHODS FOR CANCERMay 2022April 2023Abandon1100NoNo
17727888ANTI-Eva1 PROTEIN ANTIBODYApril 2022December 2023Abandon2010NoNo
17722724Heterodimeric Bispecific AntibodiesApril 2022February 2025Abandon3411NoNo
17719194Soluble Universal ADCC-Enhancing Synthetic Fusion Gene and Peptide Technology and Its Use ThereofApril 2022October 2025Abandon4240NoNo
17656732USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMABMarch 2022August 2024Abandon2900NoNo
17704057METHOD, ARRAY AND USE THEREOFMarch 2022January 2024Abandon2201NoNo
17685036ANTI-CCR8 MONOCLONAL ANTIBODIES AND USES THEREOFMarch 2022September 2023Allow1821YesNo
17674365MATERIALS AND METHODS FOR TARGETING REGULATORY T CELLS FOR ENHANCING IMMUNE SURVEILLANCEFebruary 2022September 2025Abandon4341YesNo
17582908Multiple-Variable Dosage Regimen for the Treatment of Cancers with High Expression of EGFRJanuary 2022September 2025Abandon4301NoNo
17559965BISPECIFIC ANTIBODY AGAINST CD3 AND CD20 IN COMBINATION THERAPY FOR TREATING DIFFUSE LARGE B-CELL LYMPHOMADecember 2021October 2025Abandon4641NoYes
17554941BISPECIFIC ANTIBODIES AGAINST CEACAM5 AND CD47December 2021April 2023Allow1621YesNo
17543628MULTI-SPECIFIC BINDING PROTEINS THAT BIND BCMA, NKG2D AND CD16, AND METHODS OF USEDecember 2021October 2024Abandon3451YesNo
17529017ANTI-TCR ANTIBODY MOLECULES AND USES THEREOFNovember 2021June 2023Abandon1921YesNo
17527681ANTI-CD98hc ANTIBODYNovember 2021November 2023Abandon2410NoNo
17517869TRIFUNCTIONAL ANTIGEN-BINDING MOLECULENovember 2021June 2024Abandon3120NoNo
17496051RECOMBINANT FUSION PROTEINS TARGETING CD47 AND PD-L1, PREPARATION AND USE THEREOFOctober 2021January 2023Allow1621YesNo
17492299POLYPEPTIDE DIRECTED AGAINST PROTEIN TYROSINE PHOSPHATASE 4A PROTEINS, AND COMPOSITIONS AND METHODS FOR USE THEREOFOctober 2021February 2024Abandon2911NoNo
17474980BISPECIFIC ANTIBODY MOLECULES BINDING TO CD3 AND EGFRvIIISeptember 2021October 2022Allow1321NoNo
17460591ANTIBODIES BINDING HUMAN AND MONKEY CD3 AND USES THEREOFAugust 2021August 2024Allow3541NoNo
17412445RECOMBINANT BI-FUNCTIONAL FUSION PROTEINS BINDING CD47 AND FC GAMMA RECEPTOR, PREPARATION AND USE THEREOFAugust 2021July 2023Abandon2221YesYes
17371954Classification and Treatment of Gastric CancerJuly 2021October 2023Abandon2701NoNo
17418838ANTIBODY FUSION PROTEIN, PREPARATION METHOD THEREFOR AND APPLICATION THEREOFJune 2021April 2024Abandon3401NoNo
17358902PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSJune 2021August 2022Allow1420YesNo
17356174PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST LEUKEMIAS AND OTHER CANCERSJune 2021August 2023Abandon2601NoNo
17327565METHODS FOR ENHANCING PERMEABILITY TO BLOOD-BRAIN BARRIER, AND USES THEREOFMay 2021February 2025Abandon4501NoNo
17316152ANTI-CD47 ANTIBODIES AND USES THEREOFMay 2021October 2023Allow3011YesNo
17228653BISPECIFIC FAB FUSION PROTEINS COMPRISING A CD3-BINDING FAB FRAGMENT WITH N-TERMINAL FUSION TO A BINDING DOMAIN AND METHODS OF USEApril 2021November 2024Abandon4331NoNo
17193804ANTI-C-MET ANTIBODY AND USES THEREOFMarch 2021December 2023Abandon3411NoNo
17271712Kinase Activity In TumorsFebruary 2021March 2025Abandon4911NoNo
17271909HUMANIZED ANTI-VEGFR2 SINGLE-CHAIN ANTIBODY AND USE THEREOFFebruary 2021December 2024Abandon4610NoNo
17153923PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST LEUKEMIAS AND OTHER CANCERSJanuary 2021January 2022Abandon1220YesNo
17154783METHODS OF TREATING CANCER BASED ON IDENTIFYING MUTATIONS IN THE EXTRACELLULAR DOMAIN III OF EPIDERMAL GROWTH FACTOR RECEPTOR GENEJanuary 2021November 2025Abandon5741YesNo
17153922PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSJanuary 2021January 2022Abandon1110NoNo
17259491COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS TARGETED TO CD38January 2021April 2024Abandon3901NoNo
17041559USE OF PROBDNF REGULATOR IN B CELL-RELATED DISEASESDecember 2020January 2025Abandon5211NoNo
17055103CONDITIONALLY ACTIVATED BINDING PROTEIN COMPRISING A STERICALLY OCCLUDED TARGET BINDING DOMAINNovember 2020June 2025Abandon5521NoNo
17095377DOSING REGIMENS FOR TARGETED TGF-B INHIBITION FOR USE IN TREATING CANCER IN TREATMENT NAÏVE SUBJECTSNovember 2020December 2023Abandon3701NoNo
17053558PROTEINS BINDING NKG2D, CD16 AND P-CADHERINNovember 2020January 2024Abandon3801NoNo
17091883ACTIVATABLE BISPECIFIC ANTIBODIESNovember 2020August 2023Abandon3401NoNo
17089103METHOD OF USING PACAP AND VIP PEPTIDES FOR DETECTING SHED OR CIRCULATING TUMOR CELLS IN BIOLOGICAL FLUIDSNovember 2020April 2024Abandon4120NoNo
17052196ANTIBODY SPECIFICALLY BINDING TO C-MET, AND USE THEREOFNovember 2020May 2024Allow4321YesNo
17079640Lectin Assay For Assessing Glycoforms As An Early Marker In DiseaseOctober 2020June 2024Abandon4320YesNo
16958625CHIMERIC PROMOTER WITH HIGH TRANSCRIPTIONAL ACTIVITY IN T-CELLSOctober 2020April 2025Abandon5821NoNo
17067691PROTEINS MODIFIED WITH (AMINO) MONOSACCHARIDE-BIOTIN ADDUCTOctober 2020October 2023Abandon3611NoNo
17046560SYNERGISTIC DRUG COMBINATIONS PREDICTED FROM GENOMIC FEATURES AND SINGLE-AGENT RESPONSE PROFILESOctober 2020November 2025Abandon6031YesNo
17025729PD-L1-BINDING MOLECULES COMPRISING SHIGA TOXIN A SUBUNIT SCAFFOLDSSeptember 2020November 2023Allow3821YesNo
16978278METHODS AND KITS FOR DIAGNOSING AND/OR TREATING PERIPHERAL NEUROPATHYSeptember 2020November 2024Allow5021NoNo
16996534Multispecific Antigens Binding Fragments and Multspecific AntibodiesAugust 2020March 2025Allow5540YesNo
16996510Multispecific Antigens Binding Fragments and Multspecific AntibodiesAugust 2020November 2023Allow3920YesNo
16994950USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMABAugust 2020November 2021Abandon1521NoNo
16992966USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMABAugust 2020July 2021Abandon1111NoNo
16943779ANTIGEN BINDING PROTEINS SPECIFICALLY BINDING MAGE-AJuly 2020July 2023Allow3621NoNo
16964828ANTI-CD47 ANTIBODIES THAT DO NOT CAUSE SIGNIFICANT RED BLOOD CELL AGLLUTINATIONJuly 2020September 2023Abandon3811NoNo
16962180BISPECIFIC ANTIBODY THAT BINDS CD3 AND ANOTHER TARGETJuly 2020June 2023Abandon3501NoNo
16961545ANTIBODIES AGAINST TIM3 AND USES THEREOFJuly 2020June 2024Allow4721YesNo
16916217PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSJune 2020April 2021Abandon1010NoNo
16915797PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSJune 2020April 2021Abandon910YesNo
16907820RECOMBINANT POLYPEPTIDES AND METHODS FOR USE IN THE TREATMENT OF CANCERJune 2020March 2022Abandon2131YesNo
16905262NOVEL RECOMBINANT BI-FUNCTIONAL FUSION PROTEIN TARGETING CD47 AND FCyR, PREPARATION,AND USE THEROF.June 2020January 2024Abandon4321YesNo
16904090HUMANIZED ANTIBODY MOLECULES TO CD138 AND USES THEREOFJune 2020February 2025Allow5641NoNo
16772512MELANOMA CHECKPOINT INHIBITOR DETECTION AND TREATMENTJune 2020January 2024Abandon4301NoNo
16877878CD19 BINDING MOLECULES AND USES THEREOFMay 2020January 2024Allow4421YesNo
16806658ANTI-TIGIT ANTIBODIESMay 2020May 2024Allow5031YesNo
16872974Fc Variants and Methods for their ProductionMay 2020October 2023Allow4121YesNo
16759713PREDICTING TUMOR SPECIFICITY OF TARGETED THERAPEUTICS USING ATOMIC FORCE MICROSCOPY (AFM)April 2020October 2022Abandon3001NoNo
16754604MULTISPECIFIC ANTIBODY COMPRISING CD137 BINDING DOMAIN AND PDL1 BINDING DOMAINApril 2020July 2024Allow5121NoNo
16805351PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST LEUKEMIAS AND OTHER CANCERSFebruary 2020February 2021Abandon1110NoNo
16799380PEPTIDES AND COMBINATION THEREOF FOR USE IN THE IMMUNOTHERAPY AGAINST CANCERSFebruary 2020June 2021Abandon1620NoNo
16796163USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMABFebruary 2020April 2022Abandon2631YesNo
16788442USE OF HE4 AND OTHER BIOCHEMICAL MARKERS FOR ASSESSMENT OF OVARIAN CANCERSFebruary 2020November 2023Abandon4520NoYes
16786563VARIANTS OF CD38 ANTIBODY AND USES THEREOFFebruary 2020December 2024Abandon5841YesYes
16737745ENHANCING ANTI-CANCER ACTIVITY OF IMMUNOMODULATORY FC FUSION PROTEINSJanuary 2020May 2023Abandon4020NoNo
16721254BISPECIFIC ANTIBODY MOLECULES BINDING TO CD3 AND TYRP-1December 2019January 2023Allow3731NoNo
16621314CD38 MODULATING ANTIBODY AGENTSDecember 2019December 2023Allow4841YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner ALLEN, MICHAEL D.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
12
Examiner Affirmed
9
(75.0%)
Examiner Reversed
3
(25.0%)
Reversal Percentile
37.8%
Lower than average

What This Means

With a 25.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
63
Allowed After Appeal Filing
8
(12.7%)
Not Allowed After Appeal Filing
55
(87.3%)
Filing Benefit Percentile
15.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 12.7% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner ALLEN, MICHAEL D - Prosecution Strategy Guide

Executive Summary

Examiner ALLEN, MICHAEL D works in Art Unit 1642 and has examined 488 patent applications in our dataset. With an allowance rate of 26.8%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 38 months.

Allowance Patterns

Examiner ALLEN, MICHAEL D's allowance rate of 26.8% places them in the 3% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by ALLEN, MICHAEL D receive 2.66 office actions before reaching final disposition. This places the examiner in the 78% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by ALLEN, MICHAEL D is 38 months. This places the examiner in the 28% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +52.4% benefit to allowance rate for applications examined by ALLEN, MICHAEL D. This interview benefit is in the 94% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 7.9% of applications are subsequently allowed. This success rate is in the 3% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 26.5% of cases where such amendments are filed. This entry rate is in the 37% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 60.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 50% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 58.6% of appeals filed. This is in the 33% percentile among all examiners. Of these withdrawals, 70.6% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 77.9% are granted (fully or in part). This grant rate is in the 83% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.4% of allowed cases (in the 58% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.5% of allowed cases (in the 65% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.