USPTO Examiner SZPERKA MICHAEL EDWARD - Art Unit 1641

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19074158PLATELET DERIVATIVE COMPOSITIONS, AND PLURALITIES OF CONTAINERS CONTAINING SAMEMarch 2025April 2025Allow200NoNo
18850224PEPTIDE USEFUL FOR THE TRANSPORT OF MOLECULES THROUGH CELL BARRIERSSeptember 2024June 2025Allow910NoNo
18810381METHODS USING FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR RESTORING HEMOSTASIS IN A SUBJECTAugust 2024February 2025Allow611YesNo
18770102PHOSPHO-TAU ANTIBODIES AND METHODS OF USEJuly 2024March 2025Allow811YesNo
18660156MODIFIED IMMUNOGLOBULINS FOR TARGETING AMYLOID DEPOSITSMay 2024July 2024Allow200NoNo
18660162MODIFIED IMMUNOGLOBULINS FOR TARGETING AMYLOID DEPOSITSMay 2024January 2025Allow920YesNo
18599751PHOSPHO-TAU ANTIBODIES AND METHODS OF USEMarch 2024February 2025Allow1110YesNo
18403419ANTIBODY SPECIFIC TO SPIKE PROTEIN OF SARS-COV-2 AND USES THEREOFJanuary 2024July 2024Allow610YesNo
18486053ANTI-IGE ANTIBODY THERAPY FOR MULTIPLE FOOD ALLERGIESOctober 2023May 2024Allow711YesNo
18451751ANTIBODIES TO TICAGRELOR AND METHODS OF USEAugust 2023April 2025Allow2000NoNo
18450194THERAPEUTIC ANTIBODIES THAT BIND TO THE SERINE PROTEASE DOMAIN OF MASP-2 AND USES THEREOFAugust 2023May 2024Allow921NoNo
18340722ANTI-FcRn ANTIBODY OR ANTIGEN BINDING FRAGMENT THEREOF WITH IMPROVED STABILITYJune 2023January 2024Allow710YesNo
18302033ANTI-COAGULATION FACTOR XI ANTIBODIESApril 2023December 2024Allow2010YesNo
18134430EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONSApril 2023December 2023Allow810YesNo
18182619TISSUE FACTOR PATHWAY INHIBITOR ANTIBODIES AND USES THEREOFMarch 2023August 2024Allow1700NoNo
18181489MODIFIED IMMUNOGLOBULINS FOR TARGETING AMYLOID DEPOSITSMarch 2023March 2024Allow1211YesNo
18171216ANTIBODIES CAPABLE OF BINDING TO THE SPIKE PROTEIN OF CORONAVIRUS SARS-COV-2February 2023February 2024Allow1220YesNo
18151194Antigen Binding Molecules Targeting SARS-CoV-2January 2023February 2024Allow1311NoNo
18087393SICKLED BETA GLOBIN ANTIBODIESDecember 2022November 2024Allow2210NoNo
18050240TISSUE FACTOR-TARGETED ANTIBODY-DRUG CONJUGATEOctober 2022February 2025Allow2721YesNo
18049559ANTI-BK VIRUS ANTIBODY MOLECULESOctober 2022July 2023Allow910YesNo
17958759ANTI-TNF-ALPHA-ANTIBODIES AND FUNCTIONAL FRAGMENTS THEREOFOctober 2022September 2024Allow2310YesNo
17937744ANTIBODY SPECIFIC TO SPIKE PROTEIN OF SARS-COV-2 AND USES THEREOFOctober 2022August 2023Allow1111NoNo
17935134FUSION PROTEINS OF GDF15 AND USE THEREOFSeptember 2022November 2023Allow1421YesNo
17952308MONOCLONAL ANTIBODY FOR SPIKE PROTEIN OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS, AND USE THEREOFSeptember 2022April 2024Allow1910YesNo
17946917Methods For Prevention Of Graft Rejection In XenotransplantationSeptember 2022January 2025Abandon2831NoNo
17821937NEW BINDING AGENT AND ASSAY FOR PIVKAAugust 2022March 2025Allow3121YesNo
17890857ANTI-TNF-ALPHA-ANTIBODIES AND FUNCTIONAL FRAGMENTS THEREOFAugust 2022March 2024Allow1900NoNo
17819006DNASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODSAugust 2022July 2024Abandon2411NoNo
17877853Anti-Tissue Factor Antibodies, Antibody-Drug Conjugates, and Related MethodsJuly 2022September 2024Allow2601YesNo
17814075ANTIBODIES TO FELINE MCDONOUGH SARCOMA (FMS)-LIKE TYROSINE KINASE 3 RECEPTOR LIGAND (FLT3L) AND USES THEREOF FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASESJuly 2022September 2024Allow2610YesNo
17838426ANTIBODIES TO LILRB2June 2022September 2024Abandon2801NoNo
17711517TREATMENT OF ALLERGIC DISEASES WITH CHIMERIC PROTEINApril 2022July 2024Allow2711NoNo
17699460FACTOR VII (FVII(A))/TREM-LIKE TRANSCRIPT 1 (TLT-1) BISPECIFIC ANTIBODIESMarch 2022July 2024Allow2810NoNo
17655503HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)March 2022September 2024Allow3011NoNo
17681435METHODS OF REDUCING IMMUNOGENICITY AGAINST FACTOR VIII IN INDIVIDUALS UNDERGOING FACTOR VIII THERAPYFebruary 2022March 2025Allow3721NoNo
17674438IgM-MEDIATED RECEPTOR CLUSTERING AND CELL MODULATIONFebruary 2022September 2024Abandon3101NoNo
17579517ANTI-PD-L1 ANTIBODYJanuary 2022February 2025Allow3730YesNo
17627503FACTOR H POTENTIATING ANTIBODIES AND USES THEREOFJanuary 2022July 2023Allow1810YesNo
17571075ANTIBODIES THAT RECOGNIZE RED BLOOD CELL ANTIGENSJanuary 2022February 2024Allow2510NoNo
17541932ANTI-IgE ANTIBODIESDecember 2021March 2024Allow2810NoNo
17519719FACTOR VIII CHIMERIC PROTEINS AND USES THEREOFNovember 2021January 2025Allow3821NoYes
17498112METHOD OF TREATING ATHEROSCLEROSISOctober 2021September 2024Abandon3511NoNo
17450423COAGULATION FACTOR BINDING PROTEINS AND USES THEREOFOctober 2021October 2024Abandon3601NoNo
17450122FACTOR XI ANTIBODIES AND METHODS OF USEOctober 2021February 2024Allow2811NoNo
16462878BISPECIFIC ANTIBODIES BINDING TO COAGULATION FACTOR IX AND COAGULATION FACTOR XSeptember 2021February 2025Allow6011NoNo
17459395COMPOSITIONS AND METHODS FOR EVALUATING ANTICOAGULANT THERAPEUTIC EFFICACYAugust 2021April 2025Allow4310NoNo
17407040COMPOSITIONS FOR TREATING PATHOLOGICAL CALCIFICATION CONDITIONS, AND METHODS USING SAMEAugust 2021December 2023Abandon2801NoNo
17378200METHODS OF USING FIX POLYPEPTIDESJuly 2021October 2024Abandon3910NoNo
17355530ANTIBODIES TO COAGULATION FACTOR XIA AND USES THEREOFJune 2021January 2024Abandon3101NoNo
17339021METHODS OF TREATING COMPLEMENT MEDIATED DISEASES WITH FUSION PROTEIN CONSTRUCTS COMPRISING ANTI-C3d ANTIBODY AND A COMPLEMENT MODULATORJune 2021April 2023Allow2201NoNo
17244159Method of Treating Asthma with a Complement C5 InhibitorApril 2021December 2023Allow3111YesNo
17239208CLOTTING FACTOR-FC CHIMERIC PROTEINS TO TREAT HEMOPHILIAApril 2021April 2024Abandon3601NoNo
17235198COMBINATION THERAPY WITH COAGULATION FACTORS AND MULTISPECIFIC ANTIBODIESApril 2021March 2024Abandon3501NoNo
17227029COMPOSITIONS CONTAINING ACTIVATABLE ANTIBODIESApril 2021June 2025Allow5031YesNo
17282368BI-SPECIFIC BINDING AGENTS TARGETING SYNDECAN-1 AND FIBROBLAST GROWTH FACTOR RECEPTORApril 2021November 2024Abandon4401NoNo
17277572VACCINE AND ANTIBODY AGAINST CLOSTRIDIOIDES DIFFICILE TOXINMarch 2021August 2024Abandon4101NoNo
17198199HUMAN ANTIBODY DRUG CONJUGATES AGAINST TISSUE FACTORMarch 2021February 2024Abandon3511NoNo
17274783METHODS FOR TREATING PANCREATITISMarch 2021March 2025Allow4821NoNo
17196197ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAMEMarch 2021October 2024Abandon4320NoNo
17196172PREPARATION OF FACTOR XA DERIVATIVESMarch 2021August 2023Allow2910NoNo
17271896Immunoconjugates Targeting EGFRFebruary 2021November 2024Abandon4501NoNo
17176939INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR XA DERIVATIVESFebruary 2021May 2024Abandon3910NoNo
17166648METHODS OF TREATING ACQUIRED HEMOPHILIA WITH ANTI-FIBRINOLYTIC LOADED PLATELETSFebruary 2021February 2024Abandon3710NoNo
17162982COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING LUPUSJanuary 2021January 2024Abandon3510NoNo
17257705FX ACTIVATION PROCESS AND ITS USE IN THE PREPARATION OF A FXA COMPOSITIONJanuary 2021December 2024Allow4711YesNo
17137707Antibody-based blockage of SARS-CoV-2-specific furin cleavage siteDecember 2020April 2024Abandon3911NoNo
17112280FACTOR VIII CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOFDecember 2020August 2024Allow4521NoYes
17096458ANTI-GPIIB/IIIA ANTIBODIES AND USES THEREOFNovember 2020November 2023Abandon3611NoNo
17092539ENDOSTATIN FRAGMENTS AND VARIANTS FOR USE IN TREATING FIBROSISNovember 2020October 2023Allow3531NoNo
17085128IMMUNOGLOBULINS AND USES THEREOFOctober 2020June 2024Allow4411NoNo
17076042COMPLEMENT FACTOR H ANTIBODIESOctober 2020May 2024Abandon4230YesNo
17046395ANTI-COMPLEMENT COMPONENT ANTIBODIES AND METHODS OF USEOctober 2020November 2023Abandon3711NoNo
17063905FIXaxFX Bispecific Antibody with Common Light ChainOctober 2020June 2023Allow3210NoNo
17041291METHODS OF TREATING CHRONIC SPONTANEOUS URTICARIA USING LIGELIZUMABSeptember 2020December 2023Abandon3920NoYes
16995173LYOPHILIZED FACTOR IX FORMULATIONSAugust 2020June 2024Allow4620YesYes
16994573MODIFIED FACTOR VII POLYPEPTIDES FOR SUBCUTANEOUS ADMINISTRATION AND ON-DEMAND TREATMENTAugust 2020August 2024Abandon4821NoNo
16993979FACTOR VIII POLYPEPTIDE FORMULATIONSAugust 2020April 2025Allow5631YesYes
16969788NOVEL HUMANIZED ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR, ITS NUCLEIC ACID SEQUENCE AND ITS PREPARATIONAugust 2020February 2025Allow5411YesNo
16967514METHODS OF TREATING INITIAL EPISODE OF TTP WITH IMMUNOGLOBULIN SINGLE VARIABLE DOMAINSAugust 2020January 2024Allow4231NoNo
16967294ISOLATED CHIMERIC ANTIGEN RECEPTOR, MODIFIED T CELL COMPRISING SAME AND USE THEREOFAugust 2020June 2024Abandon4601NoNo
16959652Anti-Tissue Factor Antibodies, Antibody-Drug Conjugates, and Related MethodsJuly 2020August 2024Abandon4931YesNo
16907985FACTOR IX POLYPEPTIDES AND METHODS OF USE THEREOFJune 2020October 2023Abandon3910NoNo
16771700METHODS FOR PREPARING AND USING HIGHLY ACTIVE BLOOD COAGULATION FACTOR XI MUTANT AND GENE THERAPY/EDITING VECTOR AND RECOMBINANT/FUSION PROTEIN THEREOFJune 2020December 2023Allow4210YesNo
16881911EVALUATION, ASSAYS AND TREATMENT OF PKAL-MEDIATED DISORDERSMay 2020September 2023Allow4021NoNo
16766327COMPOSITIONS FOR INTERFERON BLOCKADE AND METHODS OF USING SAMEMay 2020March 2024Allow4531NoNo
16763524FORCE SENSOR CLEAVAGE DOMAIN CONTAINING CHIMERIC POLYPEPTIDES AND METHODS OF USE THEREOFMay 2020April 2024Allow4711NoNo
16869117ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAMEMay 2020July 2023Allow3911NoNo
16761769METHOD FOR DETERMINING FACTOR XA INHIBITOR DOSAGEMay 2020November 2023Allow4221NoNo
16644355AQUEOUS PHARMACEUTICAL COMPOSITIONMarch 2020November 2023Allow4421NoNo
16643942DELIVERY OF PAYLOADS TO STEM CELLSMarch 2020February 2025Abandon6031NoNo
16630768RAPID ELICITATION OF BROADLY NEUTRALIZING ANTIBODIES TO HIV ENVJanuary 2020June 2023Allow4121NoNo
16726411STRATEGIES TO PREVENT AND/OR TREAT IMMUNE RESPONSES TO SOLUBLE ALLOFACTORSDecember 2019February 2024Abandon5021NoNo
16625109BISPECIFIC ANTIBODIES FOR FACTOR IX AND FACTOR XDecember 2019June 2023Allow4221NoYes
16622064Binding Molecule Activating FXIIDecember 2019August 2023Allow4421NoNo
16617846POLYPEPTIDES BINDING ADAMTS5, MMP13 AND AGGRECANNovember 2019July 2023Allow4341NoNo
16612476GLYCOSYLATION OF VARIABLE IMMUNOGLOBULIN DOMAINSNovember 2019September 2023Allow4631NoNo
16666886THERAPY USING A FACTOR XII INHIBITOR IN A NEUROTRAUMATIC DISORDEROctober 2019April 2024Allow5331NoNo
16494177METHODS AND COMPOSITIONS RELATED TO A TISSUE FACTOR-TARGETING IGG3 IMMUNOCONJUGATESSeptember 2019August 2023Allow4721YesNo
16537427ANTI-COAGULATION FACTOR XI ANTIBODYAugust 2019December 2023Allow5241YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner SZPERKA, MICHAEL EDWARD.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
1
Examiner Affirmed
1
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.5%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
31
Allowed After Appeal Filing
13
(41.9%)
Not Allowed After Appeal Filing
18
(58.1%)
Filing Benefit Percentile
67.2%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 41.9% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner SZPERKA, MICHAEL EDWARD - Prosecution Strategy Guide

Executive Summary

Examiner SZPERKA, MICHAEL EDWARD works in Art Unit 1641 and has examined 264 patent applications in our dataset. With an allowance rate of 86.7%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 34 months.

Allowance Patterns

Examiner SZPERKA, MICHAEL EDWARD's allowance rate of 86.7% places them in the 60% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by SZPERKA, MICHAEL EDWARD receive 1.92 office actions before reaching final disposition. This places the examiner in the 61% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by SZPERKA, MICHAEL EDWARD is 34 months. This places the examiner in the 22% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +18.9% benefit to allowance rate for applications examined by SZPERKA, MICHAEL EDWARD. This interview benefit is in the 65% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 30.5% of applications are subsequently allowed. This success rate is in the 52% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 62.5% of cases where such amendments are filed. This entry rate is in the 84% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 100.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 68% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 95.8% of appeals filed. This is in the 84% percentile among all examiners. Of these withdrawals, 91.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 37.0% are granted (fully or in part). This grant rate is in the 33% percentile among all examiners. Strategic Note: Petitions show below-average success regarding this examiner's actions. Ensure you have a strong procedural basis before filing.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 8.0% of allowed cases (in the 94% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 6.1% of allowed cases (in the 82% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.