USPTO Examiner WILSON MICHAEL C - Art Unit 1638

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18964137PLASMID ENCODING A DNAse-I AND Fc FUSION PROTEINNovember 2024August 2025Allow820NoNo
18964119PLASMID ENCODING A TLR9 AND Fc FUSION PROTEINNovember 2024October 2025Allow1120NoNo
18964155PLASMID ENCODING A NGF AND Fc FUSION PROTEINNovember 2024December 2025Allow1220NoNo
18964162PLASMID ENCODING AN INSULIN PEPTIDE AND Fc FUSION PROTEINNovember 2024December 2025Allow1220NoNo
18633883TRANSGENIC RAINBOW SHARKApril 2024October 2025Allow1811YesNo
18582222PLASMID ENCODING A TLR3 AND Fc FUSION PROTEINFebruary 2024August 2025Allow1732YesNo
18415134COMPUTER-BASED SYSTEMS FOR CONTROLLING AND MONITORING METABOLIC RATE AND ENVIRONMENTAL FACTORS OF AT LEAST ONE BIOREACTOR AND METHODS OF USE THEREOFJanuary 2024December 2025Abandon2311YesNo
18526459GENERATING ATRIAL AND VENTRICULAR CARDIOMYOCYTE LINEAGES FROM HUMAN PLURIPOTENT STEM CELLSDecember 2023July 2025Abandon1901NoNo
18521129Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses ThereofNovember 2023January 2026Abandon2610NoNo
18511290AAV CAPSIDS WITH INCREASED TROPISM TO BRAIN TISSUENovember 2023October 2025Allow2321YesNo
18450896MULTIPOTENT ADULT STEM CELLS: CHARACTERIZATION AND USEAugust 2023November 2025Abandon2721YesNo
18450549HUMAN HEMATOPOIETIC STEM CELL HAVING A MODIFIED BCL11A GENE AND METHODS OF MAKING THE CELLAugust 2023June 2025Abandon2231YesNo
18339917TRAIT SELECTION IN AVIANSJune 2023October 2025Abandon2820NoNo
18316461GENETICALLY MODIFIED MICE HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENEMay 2023March 2026Allow3410NoNo
18309466ETV2 AND USES THEREOFApril 2023December 2024Abandon2010NoNo
18250609Barcoded Cells Engineered With Heterozygous Genetic DiversityApril 2023February 2025Abandon2120NoNo
18192492METHODS FOR IMPROVING THE HEALTH OF PORCINE SPECIES BY TARGETED INACTIVATION OF CD163March 2023March 2025Allow2420NoNo
18246231METHODS FOR TREATING CANCER AND AUTOIMMUNE AND INFLAMMATORY DISEASESMarch 2023December 2025Abandon3341NoNo
17767391NON-HUMAN ALZHEIMER'S DISEASE MODEL ANIMAL AND METHOD FOR PRODUCING SAMEMarch 2023February 2026Abandon4701NoNo
18177718ANTI-IGF-I RECEPTOR ANTIBODYMarch 2023November 2025Abandon3320NoNo
18175010METHOD OF USING A GENETICALLY MODIFIED MOUSE THAT EXPRESSES HUMAN ALBUMINFebruary 2023February 2025Allow2320NoNo
18162850GUIDE RNA FOR REPAIRING A MUTANT HUMAN TITIN GENE USING CRISPR TECHNOLOGYFebruary 2023July 2025Allow2921NoNo
18159414MOUSE MODEL OF DITRA DISEASE AND USES THEREOFJanuary 2023July 2025Allow3020YesNo
18091888WNT PATHWAY STIMULATION IN REPROGRAMMING SOMATIC CELLS WITH NUCLEAR REPROGRAMMING FACTORSDecember 2022March 2026Abandon3920NoYes
18085420METHODS AND COMPOSITIONS FOR NUCLEASE-MEDIATED TARGETED INTEGRATION OF TRANSGENES INTO MAMMALIAN LIVER CELLSDecember 2022July 2024Abandon1901NoNo
18009187POULTRY CELL IN WHICH A GENE ENCODING A PROTEIN OF INTEREST IS KNOCKED-IN AT EGG WHITE PROTEIN GENE, AND METHOD FOR PRODUCING SAID POULTRY CELLDecember 2022March 2026Abandon3910NoNo
17993717METHODS OF CYTOTOXIC GENE THERAPY TO TREAT TUMORSNovember 2022July 2024Abandon2010NoNo
17919278ARTIFICIAL ONCOLYTIC VIRUSES AND RELATED METHODSOctober 2022March 2026Abandon4111NoNo
17800348GENETICALLY MODIFIED MOUSE WITH A DISRUPTION IN AN AANAT GENEAugust 2022November 2025Allow3910NoNo
17884069CELLS USEFUL FOR IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYSAugust 2022November 2024Abandon2811NoNo
17882395PLAKOPHILLIN-2 GENE THERAPY METHODS AND COMPOSITIONSAugust 2022November 2025Abandon4060YesNo
17882314PLAKOPHILLIN-2 GENE THERAPY METHODS AND COMPOSITIONSAugust 2022March 2026Abandon4370YesNo
17814791METHODS OF PRODUCING HUMAN FOREGUT ENDODERM CELLS EXPRESSING PDX1 FROM HUMAN DEFINITIVE ENDODERMJuly 2022May 2024Abandon2201NoNo
17814388GENETICALLY MODIFIED T CELL RECEPTOR MICEJuly 2022August 2024Abandon2530YesYes
17812342VIABLE GENETICALLY MODIFIED SHEEP WITH AN INACTIVATED ALPHA-1,3-GALACTOSYLTRANSFERASE (GGTA1) GENEJuly 2022January 2025Allow3141NoNo
17811089NUCLEIC ACIDS COMPRISING A MODIFIED RODENT ACTIVIN A RECEPTOR TYPE 1 (ACVR1) GENEJuly 2022May 2024Allow2210NoNo
17854286Adeno-Associated Virus Factor VIII VectorsJune 2022October 2024Allow2820YesNo
17809219PROCESS FOR USING CRISPR TO TRANSFECT PRIMORDIAL GERM CELLS IN AVIANSJune 2022September 2024Allow2730YesNo
17720369AAV VECTORS FOR VASCULAR GENE THERAPY IN CORONARY HEART DISEASE AND PERIPHERAL ISCHEMIAApril 2022February 2026Allow4631NoNo
17642938ANIMAL MODEL FOR NEURODEGENERATIVE DISORDERSMarch 2022May 2025Abandon3901NoNo
17642406METHOD OF DIFFERENTIATING PLURIPOTENT OR EPIBLAST CELLS INTO IMMATURE OOCYTESMarch 2022November 2025Allow4420NoNo
17639923METHODS FOR GENERATING ANIMAL MODELS FOR NONALCOHOLIC FATTY LIVER DISEASEMarch 2022May 2025Abandon3901NoNo
17633668GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC IL2RAFebruary 2022May 2025Abandon3901NoNo
17587590T CELL MODIFYING COMPOUNDS AND USES THEREOFJanuary 2022October 2024Abandon3321NoNo
17515139PIG WITH A GENETICALLY MODIFIED CD163 GENE RESISTANT TO PRRSVOctober 2021May 2025Allow4331NoNo
17513253MAMMALIAN SOMATIC CELL WITH MODIFIED RNA ENCODING REPROGRAMMING FACTORSOctober 2021March 2024Allow2920NoNo
17505834HUMANIZED C5 ANIMALSOctober 2021April 2025Abandon4110NoNo
17449374Method for controlling expression of a coding sequence of interest within a mammal with an inducible promoter comprising a CARE regulatory sequenceSeptember 2021November 2025Abandon5040NoNo
17459410METHOD OF USING A B4GALNT2 KNOCK OUT PIGAugust 2021June 2025Allow4620NoNo
17432364COMPOSITIONS AND METHODS TO TREAT BIETTI CRYSTALLINE DYSTROPHYAugust 2021February 2025Abandon4201NoNo
17426621METHOD FOR PRODUCING COMPOUND WITH MODIFIED MOTHER NUCLEUSJuly 2021February 2025Abandon4201NoNo
17366638ANTI-TCR ANTIBODY MOLECULES AND USES THEREOFJuly 2021October 2025Abandon5221NoNo
17345773Methods for Cardiac Fibroblast Differentiation of Human Pluripotent Stem CellsJune 2021February 2025Abandon4451YesNo
17298514SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIESMay 2021July 2025Abandon5020NoNo
17296000Food Products Comprising Avian Stem CellsMay 2021July 2025Abandon5021NoNo
17316060MAMMALIAN ALVEOLAR MACROPHAGES DERIVED FROM PLURIPOTENT CELLSMay 2021September 2024Allow4001YesNo
17241763METHODS OF USING HUMANIZED FCyR MICE TO ASSAY Fc REGIONSApril 2021March 2024Allow3420YesNo
17183263MINIMAL VOLUME REPROGRAMMING OF MONONUCLEAR CELLSFebruary 2021November 2024Allow4520NoNo
17269897METHOD OF MAKING EXOSOMES FROM TUMOR CELL/ANTIGEN PRESENTING CELL HYBRID CELLSFebruary 2021November 2024Allow4511NoNo
17168645GENETICALLY MODIFIED MSC AND THERAPEUTIC METHODSFebruary 2021November 2023Allow3310NoNo
17159564GENETICALLY MODIFIED MOUSE WITH A HUMANIZED PNPLA3 GENE AND METHODS OF USEJanuary 2021November 2024Allow4531NoNo
17262443METHOD FOR TREATING TUMOR USING IMMUNE EFFECTOR CELLJanuary 2021August 2024Abandon4210NoNo
17133142PROCESS OF TRANSFECTING PRIMORDIAL GERM CELLS IN AN AVIANDecember 2020October 2024Allow4630YesNo
17131564GENE THERAPY FOR JUVENILE BATTEN DISEASEDecember 2020January 2025Allow4940YesNo
17125368METHOD FOR PREPARING ALZHEIMER'S DISEASE (AD) ANIMAL MODELDecember 2020April 2024Abandon4020YesNo
17110868GENETICALLY MODIFIED MOUSE THAT EXPRESSES HUMANIZED PD1 AND PD-L1 PROTEINSDecember 2020May 2024Allow4121NoNo
15734535TRANSGENIC CHICKEN HAVING AN ENDOGENOUS IMMUNOGLOBULIN HEAVY CHAIN GENE IN WHICH THE IGY CH1 CODING SEQUENCE IS FUNCTIONALLY DELETEDDecember 2020November 2025Allow5941YesYes
17055003PRODUCTS FOR THERAPY OF A MUSCULOSKELETAL CONDITION AND METHODS FOR THEIR PRODUCTIONNovember 2020April 2024Abandon4101NoNo
17081470GENETICALLY MODIFIED T CELL RECEPTOR MICEOctober 2020November 2025Allow6041YesYes
17070276GENETICALLY MODIFIED CHICKEN WITH AN INACTIVATED OVOMUCOID GENEOctober 2020June 2024Abandon4430YesNo
17008506NATURAL KILLER CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR THAT BINDS CD38August 2020October 2025Allow6051NoNo
16976720CONJUGATES COMPRISING AAVs AND CAS9 POLYPEPTIDESAugust 2020April 2025Allow5641YesNo
16975422NUCLEOTIDE SEQUENCES ENCODING PEPTIDE LINKERSAugust 2020February 2024Abandon4201NoNo
16970350PLASMID ENCODING A C-TERMINAL FRAGMENT OF PARASPECKLE COMPONENT 1 FOR TREATING TUMORSAugust 2020December 2024Allow5221YesNo
16939871Universal Human Induced Pluripotent Stem Cells And Method Of Forming The SameJuly 2020April 2024Abandon4531NoNo
16938661CRISPR-RELATED METHODS AND COMPOSITIONSJuly 2020April 2024Abandon4401NoNo
16961195TRANSGENIC RAINBOW SHARKJuly 2020March 2024Allow4541YesNo
16912400REPROGRAMMING CELLSJune 2020July 2025Abandon6041NoNo
16956798PLACENTA-DERIVED CELL-CONDITIONED MEDIUM FOR INDUCING DEDIFFERENTIATION INTO INDUCED PLURIPOTENT STEM CELLS FROM SOMATIC CELLS AND METHOD FOR INDUCING DEDIFFERENTIATION USING THE SAMEJune 2020March 2024Abandon4431YesNo
16955716GAMETOGENESISJune 2020November 2025Abandon6051YesNo
16771541GENETICALLY MODIFIED RAT THAT EXPRESSES AN F54L TXN1 MUTANTJune 2020December 2023Allow4230YesNo
16759352PROCESS FOR CONTINUOUS CELL CULTURE OF GPSCSApril 2020October 2024Abandon5421YesNo
16842309METHODS AND COMPOSITIONS FOR REGENERATING HAIR CELLS AND/OR SUPPORTING CELLSApril 2020July 2024Allow5141YesNo
16835144HIGHLY FUNCTIONAL MANUFACTURED STEM CELLSMarch 2020November 2024Abandon5641NoNo
16651862FISH AND METHOD FOR PRODUCING FISHMarch 2020February 2024Abandon4740YesNo
16647474GENOME-EDITED BIRDSMarch 2020March 2026Abandon6071YesNo
16816826LOSS OF FUNCTION RODENT MODEL OF SOLUTE CARRIER 39 MEMBER 5March 2020March 2025Abandon6030YesYes
16778558METHOD OF ENHANCING VIRAL-MEDIATED GENE DELIVERYJanuary 2020April 2025Abandon6051YesNo
16634432VECTOR WITH AN ENDOTHELIAL-SPECIFIC PROMOTER FOR TREATING FACTOR V, VII, VIII, OR IX DEFICIENCYJanuary 2020July 2025Allow6041YesYes
16625999TRANSGENIC MOUSE MODEL OF NEUROFIBROMATOSIS TYPE 1December 2019March 2024Allow5131YesNo
16617787TRANSGENIC CHICKEN THAT EXPRESSES A FLUORESCENT PROTEIN AND SIAT1November 2019August 2025Allow6061YesNo
16612675MEASURING FREQUENCY OF VARIOUS SUBSETS OF PATHOGEN-SPECIFIC T CELLS IN PERIPHERAL BLOOD AS ESTABLISHED BY VARIOUS PATTERNS OF TCR-INDUCED CA2+ SIGNALINGNovember 2019May 2025Abandon6040NoNo
16607074METHOD FOR GENERATING A GENETICALLY MODIFIED PIG WITH INACTIVATED PORCINE ENDOGENOUS RETROVIRUS (PERV) ELEMENTSOctober 2019September 2023Allow4730NoNo
16600117AGENT FOR ACCELERATING MATURATION OR AGING OF CELLSOctober 2019October 2024Allow6061YesNo
16499636TRANSGENIC RAINBOW SHARKSeptember 2019June 2024Abandon5621NoYes
16530452TRANSGENIC C57BL6-BTBR MOUSE WITH A HUMANIZED MHC II GENE THAT EXPRESSES GAD65August 2019March 2024Allow5541YesNo
16476891METHOD OF TRANSDIFFERENTIATING HAIR FOLLICLE STEM CELLS INTO SPERM STEM CELLSJuly 2019October 2024Allow6080YesNo
16465006HUMANIZED MOUSE MODEL WITH IMPROVED HUMAN INNATE IMMUNE CELL DEVELOPMENTMay 2019October 2025Abandon6081NoNo
16461533METHOD OF ISOLATING MYOGENIC PROGENITORS USING CD54May 2019October 2025Allow6090YesNo
16361873TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN GENESMarch 2019March 2025Abandon6061YesYes

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner WILSON, MICHAEL C.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
12
Examiner Affirmed
6
(50.0%)
Examiner Reversed
6
(50.0%)
Reversal Percentile
69.9%
Higher than average

What This Means

With a 50.0% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
57
Allowed After Appeal Filing
19
(33.3%)
Not Allowed After Appeal Filing
38
(66.7%)
Filing Benefit Percentile
50.6%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 33.3% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner WILSON, MICHAEL C - Prosecution Strategy Guide

Executive Summary

Examiner WILSON, MICHAEL C works in Art Unit 1638 and has examined 194 patent applications in our dataset. With an allowance rate of 79.4%, this examiner has a below-average tendency to allow applications. Applications typically reach final disposition in approximately 45 months.

Allowance Patterns

Examiner WILSON, MICHAEL C's allowance rate of 79.4% places them in the 48% percentile among all USPTO examiners. This examiner has a below-average tendency to allow applications.

Office Action Patterns

On average, applications examined by WILSON, MICHAEL C receive 3.07 office actions before reaching final disposition. This places the examiner in the 88% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by WILSON, MICHAEL C is 45 months. This places the examiner in the 12% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a -1.5% benefit to allowance rate for applications examined by WILSON, MICHAEL C. This interview benefit is in the 10% percentile among all examiners. Note: Interviews show limited statistical benefit with this examiner compared to others, though they may still be valuable for clarifying issues.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 16.7% of applications are subsequently allowed. This success rate is in the 13% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 43.5% of cases where such amendments are filed. This entry rate is in the 66% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 75.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 60% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 73.3% of appeals filed. This is in the 62% percentile among all examiners. Of these withdrawals, 45.5% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 90.2% are granted (fully or in part). This grant rate is in the 88% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 17.5% of allowed cases (in the 97% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 2.6% of allowed cases (in the 71% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.