USPTO Examiner BURKHART MICHAEL D - Art Unit 1638

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18895296IMMUNE CELLS DEFECTIVE FOR SUV39H1September 2024April 2025Allow720YesNo
18773146COMPOSITION FOR REGULATING PRODUCTION OF PROTEINSJuly 2024January 2025Allow610NoNo
18596451VACCINATION WITH mRNA-CODED ANTIGENSMarch 2024May 2024Allow210NoNo
18474533Cross-Species Compatible Adeno-Associated Virus Compositions and Methods of Use ThereofSeptember 2023March 2024Allow510NoNo
18468652CARDIAC CELL REPROGRAMMING WITH MYOCARDIN AND ASCL1September 2023July 2024Allow1011NoNo
18358358MUTATED POLYPEPTIDES, COMPOSITIONS COMPRISING THE SAME, AND USES THEREOFJuly 2023November 2024Allow1610YesNo
18339157METHODS AND COMPOSITIONS FOR MODULATING CAR-T ACTIVITYJune 2023November 2023Allow500NoNo
18318507METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULESMay 2023January 2024Allow810NoNo
18118558ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAMEMarch 2023December 2023Allow910NoNo
18158173ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLSJanuary 2023December 2024Allow2331NoNo
18157421PSEUDOTYPED VIRAL PARTICLES, COMPOSITIONS COMPRISING THE SAME, AND USES THEREOFJanuary 2023August 2023Allow700NoNo
18157052METHODS AND COMPOSITIONS FOR GENOMIC INTEGRATIONJanuary 2023January 2025Allow2421NoNo
18068376METHODS AND COMPOSITIONS FOR MODIFIED FACTOR IX FUSION PROTEINSDecember 2022March 2025Allow2710NoNo
18080811EXPANDABLE CELL POPULATIONS FROM BRAIN BIOPSIES OF LIVING SUBJECTSDecember 2022November 2024Allow2300NoNo
18066175METHODS TO PRODUCE ROD-DERIVED CONE VIABILITY FACTOR (RDCVF)December 2022May 2025Abandon2910NoNo
17974123METHOD OF EXPANDING AND GENERATING A POPULATION OF CYTOKINE-INDUCED KILLER CELLS FROM PERIPHERAL BLOODOctober 2022December 2024Abandon2620NoNo
17971016METHOD AND DEVICE FOR REMOVAL OF CIRCULATING CELL FREE DNAOctober 2022March 2024Allow1712NoNo
17938501Modified Monocytes/Macrophage Expressing Chimeric Antigen Receptors and Uses ThereofOctober 2022April 2025Abandon3010NoNo
17956257Phagemid VectorSeptember 2022February 2025Allow2910NoNo
17823186HUMANIZED IL-4 AND IL-4Ra ANIMALSAugust 2022January 2025Allow2910NoNo
17893052NEW ONCOLYTIC VIRUS PLATFORM TO TREAT CANCERS WITH MYXOMA VIRUSAugust 2022February 2025Allow3010NoNo
17879559MICROORGANISMS PROGRAMMED TO PRODUCE IMMUNE MODULATORS AND ANTI-CANCER THERAPEUTICS IN TUMOR CELLSAugust 2022April 2025Abandon3310NoNo
17871383METHODS AND COMPOSITIONS FOR GENERATING PACEMAKER CELLSJuly 2022April 2025Abandon3310NoNo
17813530RNA-CODED ANTIBODYJuly 2022March 2025Abandon3210NoNo
17792713PREPARATION METHOD AND SYSTEM FOR RECOMBINANT ADENO-ASSOCIATED VIRUS, AND RECOMBINANT BACMIDJuly 2022March 2025Allow3220NoNo
17862666RAPID ASSAY FOR DETECTION OF SARS-CoV-2 ANTIBODIESJuly 2022December 2024Allow2910NoNo
17742042METHOD FOR SELECTING CELLS, METHOD FOR PRODUCING NUCLEIC ACID, METHOD FOR PRODUCING RECOMBINANT CELLS, METHOD FOR PRODUCING TARGET SUBSTANCE, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION, AND REAGENTMay 2022November 2024Allow3010NoNo
17741024VECTORS FOR THE TREATMENT OF FRIEDREICH'S ATAXIAMay 2022March 2025Allow3520NoNo
17724423METHODS OF B CELL EXPANSION FOR USE IN CELL THERAPYApril 2022February 2025Abandon3421NoNo
17659598VECTORS AND METHODS FOR REGENERATIVE THERAPYApril 2022May 2025Allow3720NoNo
17659007METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING LYMPHOCYTES TO EXPRESS POLYPEPTIDES COMPRISING THE INTRACELLULAR DOMAIN OF CD79A AND CD79BApril 2022December 2024Allow3310NoNo
17715710CHIMERIC ANTIGEN RECEPTOR DENDRITIC CELL (CAR-DC) FOR TREATMENT OF CANCERApril 2022October 2023Allow1821NoNo
17701488VECTOR SYSTEM FOR EXPRESSING REGULATORY RNAMarch 2022May 2025Allow3820NoNo
17591227BACTERIA ENGINEERED TO TREAT DISORDERS IN WHICH OXALATE IS DETRIMENTALFebruary 2022October 2024Allow3210NoNo
17571325CD19-DIRECTED CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF IN IMMUNOTHERAPYJanuary 2022February 2025Allow3730NoNo
17570352Novel Codon-Optimized CFTR MRNAJanuary 2022June 2024Abandon3010NoNo
17561659METHODS AND COMPOSITIONS FOR MODULATING CAR-T ACTIVITYDecember 2021February 2024Allow2620NoNo
17558977COMPOSITIONS FOR MODULATING AN XBP1 PATHWAY IN A KERATINOCYTE AND METHODS OF USEDecember 2021September 2024Allow3320NoNo
17528550HIGH THROUGHPUT CLONING OF PAIRED BIPARTITE IMMUNORECEPTOR POLYNUCLEOTIDES AND APPLICATIONS THEREOFNovember 2021June 2024Allow3120NoNo
17521509DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVONovember 2021April 2024Allow3010NoNo
17514711MODIFIED AAV CAPSIDS AND USES THEREOFOctober 2021February 2024Allow2810NoNo
17475116SIGLEC TRANSGENIC MICE AND METHODS OF USE THEREOFSeptember 2021March 2024Allow3010NoNo
17394492HUMANIZED IL-4 AND IL-4Ra ANIMALSAugust 2021November 2023Allow2810NoNo
17387892CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICSJuly 2021August 2024Allow3710NoNo
17383052GENE THERAPY FOR RETINITIS PIGMENTOSAJuly 2021September 2024Allow3810NoNo
17376484Co-Expression of Magnetotactic Bacterial Genes and Genes Encoding Iron Handling Proteins in CellsJuly 2021February 2024Abandon3110NoNo
17374147RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITION OF EXPRESSION OF MYOTILINJuly 2021February 2025Allow4321NoNo
17366827METHODS FOR GENERATION OF PODOCYTES FROM PLURIPOTENT STEM CELLS AND CELLS PRODUCED BY THE SAMEJuly 2021January 2024Allow3010NoNo
17332853CHIMERIC ANTIGEN RECEPTORS TARGETING FC RECEPTOR-LIKE 5 AND USES THEREOFMay 2021June 2024Allow3701NoNo
17295588Methods and Compositions for Treating OsteoarthritisMay 2021April 2025Allow4621NoNo
17306376AADC POLYNUCLEOTIDES FOR THE TREATMENT OF PARKINSON'S DISEASEMay 2021January 2024Allow3210NoNo
17211559CARDIAC CELL REPROGRAMMING WITH MYOCARDIN AND ASCL1March 2021November 2023Allow3210NoNo
17275832METHODS AND COMPOSITIONS FOR TREATING CANCER USING MRNA THERAPEUTICSMarch 2021April 2025Abandon4901NoNo
17270606BLOOD-BRAIN BARRIER PERMEABLE APTAMER AND APPLICATION THEREOFFebruary 2021April 2025Abandon4901NoNo
17250561VIRAL VECTORS ENCODING CANCER/TESTIS ANTIGENS FOR USE IN A METHOD OF PREVENTION OR TREATMENT OF CANCERFebruary 2021October 2024Allow4410NoNo
17115565CHIMERIC ANTIGEN RECEPTOR AND METHODS OF USE THEREOFDecember 2020March 2025Allow5230NoNo
17067614VACCINATION WITH mRNA-CODED ANTIGENSOctober 2020February 2024Abandon4120NoYes
17066134SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOSTIMULATORY AGENTS FOR PROPHYLACTIC AND THERAPEUTIC USEOctober 2020May 2025Abandon5630NoYes
17065003TREATMENT OF RETINITIS PIGMENTOSAOctober 2020January 2025Abandon5201NoNo
16989686METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPYAugust 2020July 2024Abandon4720NoYes
16987835Mutant IDH1 Specific T Cell ReceptorAugust 2020November 2024Abandon5101NoNo
16934925METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULESJuly 2020May 2023Allow3420NoNo
16934606ELIMINATION OF CD19-POSITIVE LYMPHOID MALIGNANCIES BY CD19-CAR EXPRESSING NK CELLSJuly 2020March 2025Allow5631NoNo
16767497Reprogrammed T Cell-Like NK CellsMay 2020March 2025Allow5721NoNo
16757263VECTORS FOR THE TREATMENT OF FRIEDREICH'S ATAXIAApril 2020May 2024Allow4910NoNo
16832321HLA G-MODIFIED CELLS AND METHODSMarch 2020March 2025Abandon6021NoNo
16643251DOUBLE SELECTION HDR CRISPR-BASED EDITINGFebruary 2020September 2024Abandon5431YesNo
16744296METHOD FOR UTILIZING ENGINEERED DENDRITIC CELLS TO INDUCE GUT-HOMING REGULATORY T CELLS AND TREAT GUT INFLAMMATIONJanuary 2020December 2024Allow5940NoYes
16616099USE OF THE IL-15/IL-15RA COMPLEX IN THE GENERATION OF ANTIGEN-SPECIFIC T CELLS FOR ADOPTIVE IMMUNOTHERAPYNovember 2019February 2025Allow6021NoNo
16613187BICISTRONIC CHIMERIC ANTIGEN RECEPTORS AND THEIR USESNovember 2019January 2024Allow5010NoNo
16474554BIFUNCTIONAL MOLECULE AND USE THEREOFNovember 2019October 2024Allow6021NoNo
16612632Systemic Delivery of PolypeptidesNovember 2019October 2024Abandon5941NoNo
16679127COMPOSITIONS AND METHODS FOR TREATMENT OF CANCERNovember 2019May 2024Abandon5401NoNo
16516286IL-31 Improves Efficacy of Macrophage-Based Adoptive Cell Therapy for CancerJuly 2019February 2024Allow5511NoNo
16516060Chimeric Antigen Receptors with BCMA Specificity and Uses ThereofJuly 2019February 2024Allow5511NoNo
16510818MENINGEAL REPAIR USING HUMAN UMBILICAL CORD PATCHESJuly 2019May 2025Allow6030NoNo
16322285TREATMENT OF CANCER USING A CHIMERIC ANTIGEN RECEPTOR IN COMBINATION WITH AN INHIBITOR OF A PRO-M2 MACROPHAGE MOLECULEJanuary 2019August 2024Abandon6021NoNo
16244909RAPID METHOD FOR CLONING AND EXPRESSION OF COGNATE ANTIBODY VARIABLE GENE SEGMENTSJanuary 2019February 2024Allow6080NoYes
16092946SALVAGE CHIMERIC ANTIGEN RECEPTOR SYSTEMSOctober 2018December 2023Allow6021NoNo
16112282Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles And Uses Thereof In Autoimmune DiseasesAugust 2018October 2024Abandon6041NoNo
16069727Genome Editing for Treating GlioblastomaJuly 2018March 2024Allow6021NoNo
15770171METHODS FOR CULTURING CELLS AND KITS AND APPARATUS FOR SAMEApril 2018October 2023Allow6031NoYes
15769241METHODS FOR GENERATING ENGINEERED HUMAN PRIMARY BLOOD DENDRITIC CELL LINESApril 2018October 2023Allow6031NoNo
15756937GENETICALLY ENGINEERED DRUG RESISTANT T CELLS AND METHODS OF USING THE SAMEMarch 2018February 2024Allow6031NoNo
15798619METHODS AND COMPOSITIONS FOR GENERATING PACEMAKER CELLSOctober 2017February 2024Allow6041YesYes
15664142METHODS AND COMPOSITIONS RELATING TO IMPROVED LENTIVIRAL VECTORS AND THEIR APPLICATIONSJuly 2017October 2018Allow1510NoNo
15650073HUMAN ARCAP TRANSGENIC MOUSEJuly 2017March 2019Allow2020NoNo
15452658VACCINATION WITH mRNA-CODED ANTIGENSMarch 2017February 2024Allow6061NoYes
15306682Gene TherapyOctober 2016April 2019Allow2930NoNo
15080020Antibody Glycosylation Variants Having Increased Antibody-Dependent Cellular CytotoxicityMarch 2016December 2016Allow1310NoNo
15015458VACCINATION IN ELDERLY PATIENTSFebruary 2016August 2024Abandon6080NoYes
14899601COVALENTLY CLOSED NON-CODING IMMUNOMODULATORY DNA CONSTRUCTDecember 2015November 2018Allow3520NoNo
14796909Glycosylation Engineering of Antibodies for Improving Antibody-Dependent Cellular CytotoxicityJuly 2015March 2017Allow2120NoNo
14665191Antibody Glycosylation Variants Having Increased Antibody-Dependent Cellular CytotoxicityMarch 2015December 2015Allow910NoNo
14489304Method of Treating Patients with a Mucinous Glycoprotein (MUC-1) VaccineSeptember 2014April 2015Allow710NoNo
14179951Bovine Adeno-Associated Viral (BAAV) Vector and Uses ThereofFebruary 2014July 2015Allow1720NoNo
14116539WDR13 AS A NOVEL BIOMARKER USEFUL FOR TREATING DIABETES AND CANCERFebruary 2014October 2015Allow2310NoNo
14136076HIGH-THROUGHPUT ANTIBODY HUMANIZATIONDecember 2013September 2016Allow3311NoNo
14022121METHODS AND COMPOSITIONS RELATING TO IMPROVED LENTIVIRAL VECTORS AND THEIR APPLICATIONSSeptember 2013January 2015Allow1610NoNo
13933382AAV4 VECTOR AND USES THEREOFJuly 2013March 2014Allow910NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner BURKHART, MICHAEL D.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
8
Examiner Affirmed
4
(50.0%)
Examiner Reversed
4
(50.0%)
Reversal Percentile
69.3%
Higher than average

What This Means

With a 50.0% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
24
Allowed After Appeal Filing
6
(25.0%)
Not Allowed After Appeal Filing
18
(75.0%)
Filing Benefit Percentile
30.3%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 25.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner BURKHART, MICHAEL D - Prosecution Strategy Guide

Executive Summary

Examiner BURKHART, MICHAEL D works in Art Unit 1638 and has examined 198 patent applications in our dataset. With an allowance rate of 86.9%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 40 months.

Allowance Patterns

Examiner BURKHART, MICHAEL D's allowance rate of 86.9% places them in the 61% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by BURKHART, MICHAEL D receive 2.09 office actions before reaching final disposition. This places the examiner in the 70% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by BURKHART, MICHAEL D is 40 months. This places the examiner in the 7% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +10.2% benefit to allowance rate for applications examined by BURKHART, MICHAEL D. This interview benefit is in the 46% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 24.8% of applications are subsequently allowed. This success rate is in the 28% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 46.9% of cases where such amendments are filed. This entry rate is in the 66% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 33.3% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 30% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 70.4% of appeals filed. This is in the 52% percentile among all examiners. Of these withdrawals, 63.2% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 53.1% are granted (fully or in part). This grant rate is in the 66% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 21.7% of allowed cases (in the 99% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.2% of allowed cases (in the 58% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.