USPTO Examiner QIAN CELINE X - Art Unit 1637

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17254191METHODS OF AAV THERAPYDecember 2020January 2025Allow4911NoNo
17057628BIOMARKERS FOR DIAGNOSING TUBERCULOUS MENINGITISNovember 2020August 2024Allow4511NoNo
17053148COMPOSITIONS AND METHODS FOR CULTURING AND EXPANDING CELLSNovember 2020April 2025Abandon5321NoNo
17090807FURTHER IMPROVED AAV VECTORS PRODUCED IN INSECT CELLSNovember 2020June 2025Allow5651NoNo
17051578IMPROVED BCL11A MICRORNAS FOR TREATING HEMOGLOBINOPATHIESOctober 2020March 2025Allow5221NoNo
16934573MYELIN OLIGODENDROCYTE GLYCOPROTEIN, MYELIN BASIC PROTEIN, AND PROTEOLIPID PROTEIN COMPOSITIONS AND METHODS OF USEJuly 2020June 2025Allow5931NoNo
16480273SYSTEMS AND METHODS FOR IMMUNOMODULATION OF MUCOSAL-ASSOCIATED INVARIANT T CELLSJuly 2019July 2024Allow6031YesNo
16435710METHOD OF EVALUATING NEUTROPHIL ACTIVITYJune 2019June 2025Abandon6061YesNo
16432107POLYPEPTIDES FOR ENGINEERING INTEGRASE CHIMERIC PROTEINS AND THEIR USE IN GENE THERAPYJune 2019April 2025Abandon6061YesNo
16463886AGENTS FOR THE TREATMENT OF PATIENTS WITH NSCLC AND METHODS TO PREDICT RESPONSEMay 2019December 2024Abandon6011NoNo
16415187PROTEIN EXPRESSION STRAINSMay 2019March 2025Allow6041YesNo
16305003PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF GENOME-EDITING MOLECULESNovember 2018January 2025Abandon6032NoNo
16092761MASSIVELY MULTIPLEXED HOMOLOGOUS TEMPLATE REPAIR FOR WHOLE-GENOME REPLACEMENTOctober 2018April 2024Abandon6040NoNo
16144822METHODS FOR PROMOTING OLIGODENDROCYTE REGENERATION AND REMYELINATIONSeptember 2018December 2024Abandon6050NoNo
16011263PLASMA CELL CYTOKINE VEHICLE CONTAINING FUSION PROTEINS FOR TARGETED INTRODUCTION OF SIRNA INTO CELLS AND TISSUESJune 2018July 2019Allow1311NoNo
15909666METHOD FOR SCREENING INDUCED PLURIPOTENT STEM CELLSMarch 2018May 2019Allow1410NoNo
15575325SCREENING METHODS FOR TARGETS FOR CANCER THERAPYNovember 2017July 2020Abandon3281YesYes
15709144HOMOLOGOUS RECOMBINATION IN MULTIPOTENT ADULT PROGENITOR CELLSSeptember 2017October 2019Allow2520NoNo
14909713METHODS FOR THE DETECTION AND TREATMENT OF LEUKEMIAS THAT ARE RESPONSIVE TO DOT1L INHIBITIONFebruary 2016April 2019Allow3921NoNo
14960136DNA MOLECULES AND METHODSDecember 2015September 2019Allow4641NoNo
14655744PGC-1beta-Protein-Function Regulator, Mitochondria-Function Regulator, Anti-Obesity Agent, And Screening Method ThereforAugust 2015May 2017Allow2311NoNo
14669957MIXER FOR REMOVING IMPURITIES FROM GASES AND LIQUIDSMarch 2015June 2015Allow300NoNo
14415064Hypoxia Inducible Factor (HIF) Activity Reporter Cell LineJanuary 2015March 2018Allow3841NoNo
14345745miRNA Biomarkers For Ulcerative ColitisSeptember 2014March 2017Allow3621NoNo
14084030Gene Cluster for Biosynthesis of Cornexistin and HydroxycornexistinNovember 2013June 2017Allow4331NoNo
13944979Enrichment of Stem Cells from Adult TissuesJuly 2013November 2015Allow2710NoNo
13864778METHOD FOR DETERMINING THE NEURODEVELOPMENTAL TOXICITY OF A COMPOUND IN VITROApril 2013June 2017Allow5030NoNo
13800478Promoters Exhibiting Endothelial Cell Specificity and Methods of Using SameMarch 2013June 2014Allow1511NoNo
13572067BIOMARKERS OF CANCER METASTASISAugust 2012January 2014Allow1720YesNo
13476305ANF-RGC IN-GENE KNOCK-OUT ANIMALMay 2012June 2014Allow2541NoNo
13454171PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAMEApril 2012April 2014Allow2430YesNo
13361628CELL CULTURE SYSTEM FOR DETERMINING THE SENSITIZING, ALLERGENIC AND/OR IRRITATING EFFECT OF A SUBSTANCEJanuary 2012July 2015Allow4140NoNo
13328785BIOMARKER DACT1 FOR GASTRIC CANCERDecember 2011June 2015Allow4231YesNo
13122119EXPRESSION VECTOR FOR ESTABLISHING HIGHLY PRODUCTIVE CELL AND THE HIGHLY PRODUCTIVE CELLMarch 2011June 2013Allow2611NoNo
13025897METHODS AND COMPOSITIONS FOR IDENTIFYING INHIBITORS OF MUTS-alpha OR MUTS-beta INTERACTION WITH MUTL-alphaFebruary 2011September 2013Allow3121NoNo
13002502METHODS AND NUCLEIC ACIDS FOR ANALYSES OF CELL PROLIFERATIVE DISORDERSFebruary 2011January 2017Allow6051YesYes
12987601TRAP VECTORS AND GENE TRAPPING METHOD BY USING THE SAMEJanuary 2011December 2013Allow3531NoNo
12974890COMPOSITIONS AND METHODS FOR TRANSFECTION OF RNA AND CONTROLLED STABILIZATION OF TRANSFECTED RNADecember 2010July 2013Allow3021NoNo
12746410IDENTIFICATION OF TOXIN LIGANDSSeptember 2010July 2013Allow3721NoNo
12842754ENRICHMENT OF STEM CELLS FROM ADULT TISSUESJuly 2010April 2013Allow3221NoNo
12778938INTEGRATION-FREE HUMAN INDUCED PLURIPOTENT STEM CELLS FROM BLOODMay 2010August 2011Allow1520YesNo
12726099RECOMBINANT CONSTRUCT FOR DETECTION OF HALOGENATED AROMATIC HYDROCARBONSMarch 2010April 2012Allow2521NoNo
12450939CONSTRUCTS FOR ENHANCEMENT OF GENE EXPRESSION IN MUSCLEMarch 2010August 2015Allow6040NoNo
12714257SCDs As Modifiers of the p53 Pathway and Methods of UseFebruary 2010March 2014Allow4930NoNo
12706683BIDIRECTIONAL PROMOTERS IN NANNOCHLOROPSISFebruary 2010July 2012Allow2921NoNo
12699180COMPOSITIONS AND METHODS FOR REGULATING RNA TRANSLATION VIA CD154 CA-DINUCLEOTIDE REPEATFebruary 2010June 2012Allow2921NoNo
12693167SYSTEM AND METHOD FOR IDENTIFYING ERYTHROPOIETIN-RESPONSIVE GENESJanuary 2010September 2012Allow3230NoNo
12643149METHODS FOR THE PREPARATION OF FIBROBLASTSDecember 2009February 2015Allow6031NoNo
12457200Promoters exhibiting endothelial cell specificity and methods of using sameJune 2009March 2014Allow5841YesNo
12410748PCRYPTORNAIMarch 2009January 2012Allow3320YesNo
12441806Facs- and Reporter Protein-Based System for High Throughput Development of Therapeutic ProteinsMarch 2009March 2025Abandon60161YesYes
12374472ASSAY AND KIT FOR PREDICTING IMPLANTATION SUCCESS IN ASSISTED FERTILISATIONJanuary 2009March 2012Allow3711YesNo
12338728sVEGFR-2 AND ITS ROLE IN LYMPHANGIOGENESIS MODULATIONDecember 2008May 2014Allow6021NoNo
12316581COMPOSITIONS AND METHODS RELATED TO MRNA TRANSLATIONAL ENHANCER ELEMENTSDecember 2008August 2012Allow4522NoNo
11573035PROCESS AND GENES FOR EXPRESSION AND OVEREXPRESSION OF ACTIVE [FeFe] HYDROGENASESNovember 2008April 2014Allow6021NoNo
12263272IMMUNOGLOBULIN DISPLAY VECTORSOctober 2008January 2011Allow2711NoNo
12225355EXPRESSION AUGMENTING DNA FRAGMENTS, USE THEREOF, AND METHODS FOR FINDING THEREOFSeptember 2008April 2011Allow3021YesNo
12233836RECOMBINATIONAL CLONING USING NUCLEIC ACIDS HAVING RECOMBINATION SITESSeptember 2008February 2010Allow1610NoNo
12195647PROMOTER FOR INTRODUCING A GENE INTO A LYMPHOCYTE OR BLOOD CELL AND APPLICATION THEREOFAugust 2008May 2011Allow3321YesNo
12195665PROMOTER FOR INTRODUCING A GENE INTO A LYMPHOCYTE OR BLOOD CELL AND APPLICATION THEREOFAugust 2008May 2011Allow3321YesNo
10574333COMPOSITIONS AND METHODS FOR GENE EXPRESSIONJuly 2008March 2012Allow6031YesNo
12161677METHOD OF IMPROVING CELL PROLIFERATION OF PANCREATIC PROGENITOR CELLS IN A PANCREATIC CELL CULTUREJuly 2008April 2017Allow6051NoNo
11991637PROMOTER FOR INTRODUCING A GENE INTO A LYMPHOCYTE OR BLOOD CELL AND APPLICATION THEREOFJuly 2008April 2011Allow3730YesNo
12156936COMBINATORIAL DNA LIBRARY FOR PRODUCING MODIFIED N-GLYCANS IN LOWER EUKARYOTESJune 2008June 2010Allow2410NoNo
12057014PSEUDO-TISSUE FOR ACCURACY CONTROL, METHOD FOR CONTROLLING ACCURACY BY USING THE SAME, AND METHOD FOR MANUFACTURING THE SAMEMarch 2008March 2015Allow6041NoNo
12052268USE OF THERAPEUTICALLY EFFECTIVE LIPIDS AND METHOD FOR PRODUCING ORGAN-/TISSUE-SPECIFIC THERAPEUTICALLY EFFECTIVE LIPIDSMarch 2008July 2014Allow6041NoNo
12052674AMBULATORY PATIENT MONITORING APPARATUS, SYSTEM AND METHODMarch 2008September 2014Allow6021YesNo
12048599MULTIPLE PROMOTERS AND THE USE THEREOF FOR GENE EXPRESSIONMarch 2008February 2011Allow3520YesNo
12037117EXPRESSION VECTOR, A TRANSFORMANT CARRYING THE SAME AND A METHOD FOR PRODUCING HETEROLOGOUS PROTEINFebruary 2008April 2010Allow2510NoNo
12036722BIASING OF CELLS TOWARD RETINAL, CORNEAL OR LENS DEVELOPMENTFebruary 2008September 2015Allow6081YesYes
11995398REPORTER VECTOR FOR USE IN EVALUATION OF CYP1A2 INDUCTIONFebruary 2008November 2010Allow3420NoNo
11949306MODULATORS OF THE ORPHAN G PROTEIN-COUPLED RECEPTORS GPR78 AND GPR26December 2007September 2010Allow3411NoNo
11926203METHYL-CPG ISLAND-ASSOCIATED GENOME SIGNATURE TAGSOctober 2007March 2014Allow6031NoNo
11874838JAB1 AS A PROGNOSTIC MARKER AND A THERAPEUTIC TARGET FOR HUMAN CANCEROctober 2007December 2013Allow6020NoYes
11840903IDENTIFICATION OF GENESAugust 2007June 2010Allow3421NoNo
11890842Epididymal lipocalin gene and uses thereofAugust 2007July 2013Allow6021YesNo
11801641UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOFMay 2007December 2010Allow4321NoNo
11726388TELOMERASE EXPRESSION REPRESSOR PROTEINS AND METHODS OF USING THE SAMEMarch 2007April 2010Allow3720NoNo
11578476Transgenomic Mitochondria, Transmitochondrial Cells and Organisms, and Methods of Making and UsingOctober 2006January 2013Allow6051NoNo
11494363METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESISJuly 2006December 2009Allow4131YesNo
10585149Transactivation system for mammalian cellsJune 2006October 2012Allow6041NoNo
10933874MULTI-ANTIGEN VECTORS OF MELANOMASeptember 2004August 2009Abandon5941NoNo
10893235RECOMBINATIONAL CLONING USING NUCLEIC ACIDS HAVING RECOMBINATION SITESJuly 2004March 2008Allow4812NoNo
10858271COMPOSITIONS AND METHODS FOR SENSITIZING AND INHIBITING GROWTH OF HUMAN TUMOR CELLSJune 2004September 2008Allow5232NoNo
10806515METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING MALE ERECTILE DYSFUNCTIONMarch 2004August 2008Allow5321NoNo
10741509CHOLESTEROL REDUCTION SIGNATUREDecember 2003July 2008Allow5531NoNo
10731739HIGH BONE MASS GENE OF 11Q13.3December 2003June 2007Allow4321NoNo
10702319COMPOSITIONS AND METHODS FOR THE MODIFICATION OF GENE EXPRESSIONNovember 2003December 2010Allow6061YesYes
10696708MUTATIONS IN AND GENOMIC STRUCTURE OF HERG - A LONG QT SYNDROME GENEOctober 2003June 2007Allow4420NoNo
10467104METHODS AND KITS FOR IDENTIFYING SCAVENGERS OF REACTIVE OXYGEN SPECIES (ROS)August 2003February 2008Allow5460YesYes
10603387METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESISJune 2003April 2006Allow3411NoNo
10457604MUTATED HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASES AND USES THEREOFJune 2003August 2005Allow2610NoNo
10239595ESTABLISHMENT OF CELLULAR MANIPULATIONS WHICH ENHANCE OLIGO-MEDIATED GENE TARGETINGMarch 2003September 2007Allow6030YesNo
10371877COMBINATORIAL DNA LIBRARY FOR PRODUCING MODIFIED N-GLYCANS IN LOWER EUKARYOTESFebruary 2003February 2008Allow6031NoNo
10204884CORNEODESMOSIN BASED TEST AND MODEL FOR INFLAMMATORY DISEASEJanuary 2003August 2007Allow6021YesYes
10347718MAMMARY GLAND TISSUE-SPECIFIC EXPRESSION SYSTEM USING BETA-CASEIN PROMOTER SITE OF KOREAN NATIVE GOATJanuary 2003December 2005Allow3511NoNo
10338691ISOLATED HUMAN DRUG-METABOLIZING PROTEINS, NUCLEIC ACID MOLECULES ENCODING HUMAN DRUG-METABOLIZING PROTEINS, AND USES THEREOFJanuary 2003December 2004Allow2301NoNo
10336091UPSTREAM CONTROL ELEMENTS OF THE PROOPIOMELANOCORTIN GENE AND THEIR USEJanuary 2003May 2006Allow4021NoNo
10319564ADULT T CELL LEUKEMIA MODEL ANIMALDecember 2002May 2006Allow4110NoNo
10181545MYOSTATIN AND MIMETICS THEREOFNovember 2002September 2007Allow6051NoYes

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner QIAN, CELINE X.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
2
Examiner Affirmed
1
(50.0%)
Examiner Reversed
1
(50.0%)
Reversal Percentile
69.9%
Higher than average

What This Means

With a 50.0% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is above the USPTO average, indicating that appeals have better success here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
21
Allowed After Appeal Filing
7
(33.3%)
Not Allowed After Appeal Filing
14
(66.7%)
Filing Benefit Percentile
51.3%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 33.3% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner QIAN, CELINE X - Prosecution Strategy Guide

Executive Summary

Examiner QIAN, CELINE X works in Art Unit 1637 and has examined 143 patent applications in our dataset. With an allowance rate of 92.3%, this examiner allows applications at a higher rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 40 months.

Allowance Patterns

Examiner QIAN, CELINE X's allowance rate of 92.3% places them in the 78% percentile among all USPTO examiners. This examiner is more likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by QIAN, CELINE X receive 2.69 office actions before reaching final disposition. This places the examiner in the 75% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by QIAN, CELINE X is 40 months. This places the examiner in the 23% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a -4.6% benefit to allowance rate for applications examined by QIAN, CELINE X. This interview benefit is in the 7% percentile among all examiners. Note: Interviews show limited statistical benefit with this examiner compared to others, though they may still be valuable for clarifying issues.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 25.4% of applications are subsequently allowed. This success rate is in the 43% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 51.4% of cases where such amendments are filed. This entry rate is in the 78% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 50.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 43% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 86.7% of appeals filed. This is in the 80% percentile among all examiners. Of these withdrawals, 92.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 76.6% are granted (fully or in part). This grant rate is in the 81% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 15.4% of allowed cases (in the 97% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 3.0% of allowed cases (in the 76% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.