USPTO Examiner POLIAKOVA GEORGAN EKATERINA - Art Unit 1637

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19214546METHODS AND COMPOSITIONS FOR TREATING A PROPROTEIN CONVERTASE SUBTILISIN KEXIN (PCSK9) GENE-ASSOCIATED DISORDERMay 2025January 2026Allow820NoNo
19034336COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACIDJanuary 2025December 2025Allow1120NoNo
18752290MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNASJune 2024January 2025Allow701NoNo
18657650NOVEL COMPOUND AND APPLICATION THEREOFMay 2024August 2025Allow1630YesNo
18640905INHIBITORS OF EXPRESSION AND/OR FUNCTIONApril 2024March 2025Allow1110NoNo
18621742RNase InhibitorsMarch 2024October 2025Allow1810NoNo
18317177OLIGONUCLEOTIDE AND USE THEREOF AGAINST HEPATITIS B VIRUS AND HEPATITIS D VIRUSMarch 2024December 2024Abandon2010NoNo
18582279COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACIDFebruary 2024February 2025Allow1220NoNo
18443300ANTISENSE OLIGONUCLEOTIDES TARGETING SCN2A FOR THE TREATMENT OF SCN1A ENCEPHALOPATHIESFebruary 2024January 2026Allow2310NoNo
18441001COMPOSITIONS AND METHODS FOR INHIBITING TRANSMEMBRANE SERINE PROTEASE 6 (TMPRSS6) EXPRESSIONFebruary 2024November 2025Allow2111NoNo
18523743DIAGNOSTIC KIT FOR METASTASIS AND INVASION OF BREAST CANCER AND USE OF shRNA MOLECULE FOR SILENCING EXPRESSION OF HUMAN LINC01614November 2023March 2025Allow1520NoNo
18523746Compounds and Methods for Reducing LRRK2 ExpressionNovember 2023August 2024Allow900NoNo
18509899RNase InhibitorsNovember 2023October 2025Allow2310NoNo
18507175METHODS AND COMPOSITIONS FOR TREATING A PROPROTEIN CONVERTASE SUBTILISIN KEXIN (PCSK9) GENE-ASSOCIATED DISORDERNovember 2023May 2025Abandon1801NoNo
18503748MICELLAR NANOPARTICLES AND USES THEREOFNovember 2023March 2026Abandon2821NoNo
18383073ANGIOTENSINOGEN (AGT) iRNA COMPOSITIONS AND METHODS OF USE THEREOFOctober 2023November 2025Allow2521NoNo
18484291PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOFOctober 2023May 2025Abandon2001NoNo
18374166COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TMPRSS6 GENESeptember 2023October 2025Allow2511NoNo
18473936ANTISENSE OLIGONUCLEOTIDE AND COMPOSITION FOR PREVENTION OR TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE IASeptember 2023December 2025Abandon2610NoNo
18346686NUCLEIC ACIDS ENCODING CRISPR-ASSOCIATED PROTEINS AND USES THEREOFJuly 2023March 2025Allow2001NoNo
18345407THERAPEUTIC OLIGONUCLEOTIDESJune 2023April 2025Allow2111NoNo
18333007Selective Antisense Compounds and Uses ThereofJune 2023March 2025Abandon2101NoNo
18321996REGULATION OF GENE EXPRESSION THROUGH APTAMER-MODULATED POLYADENYLATIONMay 2023October 2025Allow2911NoNo
18314258RNA-Editing Oligonucleotides and Uses ThereofMay 2023August 2024Allow1521NoNo
18130278METHODS AND COMPOSITIONS FOR TREATING A PREMATURE STOP CODON-MEDIATED DISORDERApril 2023December 2024Abandon2110NoNo
18187524METHODS FOR INTRACELLULAR DELIVERY AND ENHANCED GENE TARGETINGMarch 2023September 2025Abandon3010NoNo
18178206ANTI-C9ORF72 OLIGONUCLEOTIDES AND RELATED METHODSMarch 2023March 2025Allow2421NoNo
18156231Novel Replicase Cycling Reaction (RCR) and the Related SamRNA Designs ThereofJanuary 2023March 2026Allow3811NoNo
18146840Adeno-Associated Virus Vector Delivery of Muscle Specific Micro-Dystrophin to Treat Muscular DystrophyDecember 2022April 2025Abandon2810NoNo
18001853COMPOUNDS AND METHODS FOR REDUCING KCNT1 EXPRESSIONDecember 2022August 2025Allow3200NoNo
18061371COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDSDecember 2022March 2026Abandon4010NoNo
18059606REGULATION OF GENE EXPRESSION VIA APTAMER-MEDIATED CONTROL OF SELF-CLEAVING RIBOZYMESNovember 2022March 2025Allow2811NoNo
18058664COMPLEMENT FACTOR B-MODULATING COMPOSITIONS AND METHODS OF USE THEREOFNovember 2022February 2026Allow3920YesNo
18054813DNA COMPOSITIONS AND RELATED METHODSNovember 2022January 2025Allow2641YesNo
18054113COMPLEMENT COMPONENT C1R INHIBITORS FOR TREATING A NEUROLOGICAL DISEASE, AND RELATED COMPOSITIONS, SYSTEMS AND METHODS OF USING SAMENovember 2022February 2026Abandon3901NoNo
17924063Methods and Compositions for the ADAR-Mediated Editing of ABCA4November 2022February 2026Abandon4001NoNo
18052785METHODS AND COMPOSITIONS FOR MACROPHAGE POLARIZATIONNovember 2022November 2025Allow3641NoNo
17919611PD-1-specific antisense oligonucleotide and its use in therapyOctober 2022February 2026Abandon4010NoNo
17918877METHOD AND DRUG FOR TREATING HURLER SYNDROMEOctober 2022February 2026Abandon4001NoNo
18046235ANTISENSE THERAPEUTICS FOR THE TREATMENT OF CORONAVIRUSOctober 2022February 2026Abandon4010NoNo
18045109OLIGONUCLEOTIDES FOR REDUCTION OF PD-L1 EXPRESSIONOctober 2022September 2025Allow3621NoNo
17960090OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOFOctober 2022March 2025Abandon2911NoNo
17907189Aptamers That Bind Thiamine Analogs and DerivativesSeptember 2022November 2025Allow3701YesNo
17912510GENE SILENCING AGENTS FOR TARGETING CORONAVIRUS GENES AND USES THEREOFSeptember 2022February 2026Abandon4110NoNo
17906500TREATMENT OF COVID-19 WITH REVERSE MICELLE SYSTEM COMPRISING UNMODIFIED OLIGONUCLEOTIDESSeptember 2022February 2026Abandon4110NoNo
17911665COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSISSeptember 2022February 2026Abandon4110NoNo
17911343COMPOSITIONS FOR THE TREATMENT OF NASH AND ASSOCIATED DISORDERS AND METHODS OF USING SAMESeptember 2022February 2026Abandon4110NoNo
17821693TREATMENT OF THYMIC STROMAL LYMPHOPOIETIN (TSLP) RELATED DISEASES BY INHIBITION OF LONG-FORM TSLP TRANSCRIPTSAugust 2022July 2025Abandon3511NoNo
17818858RIBONUCLEIC ACIDS WITH 4'-THIO-MODIFIED NUCLEOTIDES AND RELATED METHODSAugust 2022November 2024Allow2721NoNo
17760343MIRNA-485 INHIBITOR FOR GENE UPREGULATIONAugust 2022February 2026Abandon4210NoNo
17817874RNA-Editing Oligonucleotides and Uses ThereofAugust 2022May 2025Allow3311NoNo
17811961siRNA based on RNA sequence of SARS-CoV-2 and use thereofJuly 2022September 2024Allow2621NoNo
17851227Materials and Methods for Treatment of Myotonic Dystrophy Type 1 (DM) and Other Related DisordersJune 2022August 2025Abandon3721YesNo
17846457INHIBITION OF POLYOMAVIRUS REPLICATIONJune 2022July 2025Allow3720YesNo
17784878Allele-Specific Silencing of Transforming Growth Factor Beta Induced Gene with R124H Mutation Using Short Interfering RNAJune 2022March 2026Abandon4501NoNo
17829801Treatment Of Cerebrovascular Disease With Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) AgentsJune 2022September 2024Allow2751NoNo
17748961MODULATORS OF GROWTH HORMONE RECEPTORMay 2022March 2026Abandon4610NoNo
17732757TREATMENT METHODS FOR MUSCULAR DYSTROPHYApril 2022January 2025Allow3210NoNo
17768914SOLUTE CARRIER FAMILY MEMBER IRNA COMPOSITIONS AND METHODS OF USE THEREOFApril 2022August 2025Allow4001NoNo
17688754COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSIONMarch 2022February 2026Abandon4810NoNo
17680940Treatment Of Liver Disease With Mitochondrial Glycerol-3-Phosphate Acyltransferase (GPAM) InhibitorsFebruary 2022September 2024Allow3131NoNo
17648340Novel RNA Composition and Production Method for Use in iPS Cell GenerationJanuary 2022December 2025Abandon4701NoNo
17570714MICRORNAS FOR CARDIAC REGENERATION THROUGH INDUCTION OF CARDIAC MYOCYTE PROLIFERATIONJanuary 2022April 2025Allow3931NoNo
17623569NOVEL COMPOUND AND APPLICATION THEREOFDecember 2021April 2025Allow3921YesNo
17621449ANTISENSE OLIGONUCLEOTIDE CAPABLE OF ALTERING SPLICING OF DUX4 pre-mRNADecember 2021October 2025Abandon4601NoNo
17548995COMPOSITION FOR DELIVERY OF GENETIC MATERIALDecember 2021November 2025Abandon4731NoNo
17544984SERUM AMYLOID P COMPONENT (APCS) iRNA COMPOSITIONS AND METHODS OF USE THEREOFDecember 2021December 2024Abandon3611NoNo
17529119Compound for treatment of heart failureNovember 2021December 2025Allow4951NoNo
17522754COMPOSITIONS FOR DELIVERY OF CODON-OPTIMIZED MRNANovember 2021November 2025Allow4841YesNo
17594740OLIGOMERIC NUCLEIC ACID MOLECULE, AND APPLICATION THEREOF IN AN ACUTE INTERMITTENT PORPHYRIA TREATMENTOctober 2021December 2025Allow5011NoNo
17607102APTAMER NUCLEIC ACID MOLECULE, AND COMPLEX AND APPLICATION THEREOFOctober 2021January 2026Allow5101NoNo
17605908DOUBLE-STRANDED NUCLEIC ACID INHIBITOR MOLECULES WITH SHORTENED SENSE STRANDSOctober 2021October 2025Allow4821NoNo
17604510METHODS FOR THE TREATMENT AND PROGNOSIS OF CANCEROctober 2021July 2025Abandon4501NoNo
17489357NOVEL MRNA COMPOSITION AND PRODUCTION METHOD FOR USE IN ANTI-VIRAL AND ANTI-CANCER VACCINESSeptember 2021November 2025Allow5050NoNo
17471719GAPMER ANTISENSE OLIGONUCLEOTIDES TARGETING SARS-COV-2 FOR TREATING COVID 19September 2021July 2024Allow3431NoNo
17437507COMPOUNDS AND METHODS FOR REDUCING KCNT1 EXPRESSIONSeptember 2021November 2024Allow3800NoNo
17437123NON-VIRAL DNA VECTORS AND USES THEREOF FOR EXPRESSING FVIII THERAPEUTICSSeptember 2021February 2025Allow4101NoNo
173719355'-CAP COMPOUNDS AND THEIR USES IN STABILIZING RNA, EXPRESSING PROTEINS AND IN THERAPYJuly 2021December 2024Abandon4161YesYes
17372173MODULATION OF APOLIPOPROTEIN C-III (APOCIII) EXPRESSION IN LIPOPROTEIN LIPASE DEFICIENT (LPLD) POPULATIONSJuly 2021March 2024Allow3360NoNo
17420460RNAi Agents for Inhibiting Expression of HIF-2 alpha (EPAS1), Compositions Thereof, and Methods of UseJuly 2021August 2024Allow3800NoNo
17339366P-ETHOXY NUCLEIC ACIDS FOR STAT3 INHIBITIONJune 2021January 2025Allow4440NoNo
17319391CCR7 APTAMERS AND USES THEREOFMay 2021August 2024Allow4020NoNo
17314962SYSTEMS AND METHODS FOR USE OF ADENOSINE TRIPHOSPHATE (ATP) TO RELIEVE SYMPTOMS OF COVID-19 AND RELATED INFECTIONSMay 2021March 2025Allow4630YesNo
17239461DISEASE STRATIFICATION OF LIVER DISEASE AND RELATED METHODSApril 2021November 2024Abandon4201NoNo
16606433P-ETHOXY NUCLEIC ACIDS FOR IGF-1R INHIBITIONApril 2021December 2025Abandon6030YesNo
17211622NUCLEIC ACIDS FOR CELL RECOGNITION AND INTEGRATIONMarch 2021June 2025Allow5111NoNo
17268590Inducing Proliferation of Cardiomyocytes and Therapeutic Uses Related TheretoFebruary 2021January 2025Allow4721YesNo
17175156OLIGONUCLEOTIDES TARGETING FRATAXIN AND RELATED METHODSFebruary 2021January 2025Allow4731YesYes
17258544METHODS FOR TARGETING PAIN DIRECTED AT METABOLIC PATHWAYSJanuary 2021July 2024Allow4201NoNo
16973464EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHYDecember 2020May 2025Abandon5311NoNo
17048236GENE THERAPY FOR DISEASES CAUSED BY UNBALANCED NUCLEOTIDE POOLS INCLUDING MITOCHONDRIAL DNA DEPLETION SYNDROMESOctober 2020June 2025Allow5621NoNo
17023003COMPOSITION FOR TEMPERATURE SENSORS INCLUDING GRAPHENE OXIDE, DNAZYME AND PNA AND TEMPERATURE SENSING METHOD USING THE SAMESeptember 2020September 2024Allow4811NoNo
169803005'-CAP-TRINUCLEOTIDE- OR HIGHER OLIGONUCLEOTIDE COMPOUNDS AND THEIR USE IN STABILIZING RNA, EXPRESSING PROTEINS IN THERAPYSeptember 2020January 2025Allow5231YesNo
16971626CANCER THERAPEUTIC TARGETING USING MUTANT P53-SPECIFIC SIRNASAugust 2020August 2025Allow6021NoNo
16969897POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDESAugust 2020September 2025Allow6050YesYes
16963583METHOD OF INTRODUCING AN mRNA MOLECULE INTO A CELLJuly 2020November 2024Allow5221YesNo
16960508IMMUNE-ENHANCING RNAS FOR COMBINATION WITH CHIMERIC ANTIGEN RECEPTOR THERAPYJuly 2020September 2025Allow6031YesNo
16896811METHODS OF IMPROVING ADENO-ASSOCIATED VIRAL TRANSDUCTIONJune 2020September 2024Allow5250YesNo
16626395ANTISENSE OLIGONUCLEOTIDES FOR MODULATING THE FUNCTION OF A T CELLDecember 2019August 2024Allow5641NoNo
15974941TRANSCRIPTOMIC INDEX FOR CHARACTERIZING THE CELLULAR REPAIR RESPONSE AFTER SOFT TISSUE INJURY IN DIARTHRODIAL JOINTSMay 2018January 2025Allow6050NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner POLIAKOVA-GEORGAN, EKATERINA.

Strategic Value of Filing an Appeal

Total Appeal Filings
5
Allowed After Appeal Filing
2
(40.0%)
Not Allowed After Appeal Filing
3
(60.0%)
Filing Benefit Percentile
64.9%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 40.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is above the USPTO average, suggesting that filing an appeal can be an effective strategy for prompting reconsideration.

Strategic Recommendations

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner POLIAKOVA-GEORGAN, EKATERINA - Prosecution Strategy Guide

Executive Summary

Examiner POLIAKOVA-GEORGAN, EKATERINA works in Art Unit 1637 and has examined 54 patent applications in our dataset. With an allowance rate of 85.2%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 46 months.

Allowance Patterns

Examiner POLIAKOVA-GEORGAN, EKATERINA's allowance rate of 85.2% places them in the 61% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by POLIAKOVA-GEORGAN, EKATERINA receive 2.33 office actions before reaching final disposition. This places the examiner in the 66% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by POLIAKOVA-GEORGAN, EKATERINA is 46 months. This places the examiner in the 10% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +4.5% benefit to allowance rate for applications examined by POLIAKOVA-GEORGAN, EKATERINA. This interview benefit is in the 28% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 22.7% of applications are subsequently allowed. This success rate is in the 29% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 33.3% of cases where such amendments are filed. This entry rate is in the 49% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 100.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 69% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 86% percentile among all examiners. Of these withdrawals, 100.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 57.1% are granted (fully or in part). This grant rate is in the 59% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 1.9% of allowed cases (in the 74% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.