USPTO Examiner HASAN KHALEDA B - Art Unit 1636

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19048826LIPID COMPOSITION TARGETING ANTIGEN-PRESENTING CELLS AND USE THEREOFFebruary 2025September 2025Allow710NoNo
18758151METHODS AND COMPOSITIONS FOR TREATING AND PROTECTING AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUSJune 2024July 2025Allow1320NoNo
18737778IMMUNOCOMPETENT CELL AND EXPRESSION VECTOR EXPRESSING REGULATORY FACTORS OF IMMUNE FUNCTION, AND CHIMERIC ANTIGEN RECEPTORJune 2024December 2025Abandon1821NoNo
18669712ENDONUCLEASE SYSTEMSMay 2024May 2025Allow1111YesNo
18653454BASE EDITING ENZYMESMay 2024August 2025Allow1511YesNo
18702749GENE EDITING METHODS FOR TREATING ALPHA-1 ANTITRYPSIN (AAT) DEFICIENCYApril 2024March 2026Allow2310NoNo
18597673RIBOSWITCH MODULATED GENE THERAPY FOR RETINAL DISEASESMarch 2024December 2024Allow1010YesNo
18477788POLYRIBONUCLEOTIDES CONTAINING REDUCED URACIL CONTENT AND USES THEREOFSeptember 2023September 2025Abandon2410NoNo
18474327Therapeutic EditingSeptember 2023February 2026Abandon2901NoNo
18472824ENGINEERED RETRONS AND METHODS OF USESeptember 2023March 2024Allow600YesNo
18457276ENGINEERED ADENOSINE DEAMINASES AND BASE EDITORS THEREOFAugust 2023August 2024Allow1211YesNo
18447536METHODS AND COMPOSITIONS FOR MODULATING A GENOMEAugust 2023February 2024Allow601YesNo
18447681METHODS AND COMPOSITIONS FOR MODULATING A GENOMEAugust 2023June 2024Allow1011YesNo
18447515METHODS AND COMPOSITIONS FOR MODULATING A GENOMEAugust 2023February 2024Allow601YesNo
18362867Compositions and Methods Comprising a TTR Guide RNA and a Polynucleotide Encoding an RNA-Guided DNA Binding AgentJuly 2023March 2026Allow3141YesNo
18356013METHODS AND COMPOSITIONS FOR MODULATING A GENOMEJuly 2023February 2024Allow701YesNo
18355380COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERSJuly 2023September 2025Allow2620YesNo
18331092ENGINEERING CELL LINES CAPABLE OF PROLIFERATION IN GROWTH FACTOR FREE MEDIA FORMULATIONSJune 2023November 2025Allow3041YesNo
18319042GENE EDITING-BASED METHOD OF ATTENUATING THE BETA-AMYLOID PATHWAYMay 2023August 2025Allow2710NoNo
18127936IMMUNOENGINEERED PLURIPOTENT CELLSMarch 2023September 2024Abandon1800NoNo
18190063CRISPR SYSTEMS WITH ENGINEERED DUAL GUIDE NUCLEIC ACIDSMarch 2023December 2024Allow2121YesNo
18120007USE NOVEL LIGHT SENSITIVE CHANNEL PROTEIN VR 1.0 IN PREPARATION OF RETINAL PHOTORECEPTOR CELL DEGENERATIVE DISEASE DRUGMarch 2023January 2024Allow1010NoNo
18174397COMPOSITIONS, METHODS, MODULES AND INSTRUMENTS FOR AUTOMATED NUCLEIC ACID-GUIDED NUCLEASE EDITING IN MAMMALIAN CELLS USING MICROCARRIERSFebruary 2023September 2025Abandon3120NoNo
18109759Process for extracellular secretion of BrazzeinFebruary 2023December 2025Allow3410NoNo
18161560ENGINEERED MEGANUCLEASES THAT TARGET HUMAN MITOCHONDRIAL GENOMESJanuary 2023August 2023Allow700YesNo
18101867ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS, ENZYMES AND GUIDE SCAFFOLDS OF CAS9 ORTHOLOGS AND VARIANTS FOR SEQUENCE MANIPULATIONJanuary 2023September 2024Allow2010NoNo
18087673ENGINEERED RETRONS AND METHODS OF USEDecember 2022September 2023Allow810YesNo
18049582ALTERNATIVE NUCLEIC ACID MOLECULES CONTAINING REDUCED URACIL CONTENT AND USES THEREOFOctober 2022June 2025Abandon3201NoNo
17963889CRISPR SYSTEMS WITH ENGINEERED DUAL GUIDE NUCLEIC ACIDSOctober 2022November 2025Abandon3721NoNo
17931535Guide RNAs with Chemical Modification for Prime EditingSeptember 2022September 2023Allow1220YesNo
17848330ENGINEERED TARGET SPECIFIC NUCLEASESJune 2022January 2026Abandon4301NoNo
17781877Therapeutic EditingJune 2022August 2023Allow1410YesNo
17825665CODON OPTIMIZED RPGRORF15 GENES AND USES THEREOFMay 2022June 2023Abandon1310NoNo
17751195Adeno-Associated Virus Vector Delivery of a Fragment of Micro-Dystrophin to Treat Muscular DystrophyMay 2022October 2023Allow1730YesNo
17748889Immunocompetent Cell and Expression Vector Expressing Regulatory Factors of Immune FunctionMay 2022November 2023Allow1820YesNo
17738585NOVEL METHODS FOR EARLY IDENTIFICATION OF BONE HEALING ABILITY IN INJURED PATIENTSMay 2022February 2026Allow4521YesNo
17710464COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS TARGETING TRIM7March 2022May 2024Allow2611NoNo
17654300ADENO-ASSOCIATED VIRUS COMPOSITIONS FOR RESTORING F8 GENE FUNCTION AND METHODS OF USE THEREOFMarch 2022July 2023Allow1610YesNo
17580228ADENO-ASSOCIATED VIRUS VECTOR DELIVERY OF B-SARCOGLYCAN AND MICRORNA-29 AND THE TREATMENT OF MUSCULAR DYSTROPHYJanuary 2022October 2023Allow2120YesNo
17529936RECOMBINASE-RECOGNITION SITE PAIRS AND METHODS OF USENovember 2021July 2025Abandon4411NoNo
17525283METHOD FOR CONSTRUCTING TREHALOSE MULTI-ENZYME COMPLEX IN VITRO MEDIATED BY ARTIFICIAL SCAFFOLD PROTEINNovember 2021May 2024Allow3011YesNo
17523821ELECTROPORATION MODULES AND INSTRUMENTATIONNovember 2021January 2023Allow1510NoNo
17453702GENE THERAPY METHODSNovember 2021August 2025Abandon4601NoNo
17506419METHODS AND COMPOSITIONS FOR DIRECTED GENOME EDITINGOctober 2021February 2025Abandon4021NoNo
17506572CRISPR SYSTEMS WITH ENGINEERED DUAL GUIDE NUCLEIC ACIDSOctober 2021October 2025Allow4821NoNo
17494457Gene Editing-Based Method of Attenuating the Beta-Amyloid PathwayOctober 2021February 2023Allow1710YesNo
17490416HUMAN PAH EXPRESSION CASSETTE FOR TREATMENT OF PKU BY LIVER-DIRECTED GENE REPLACEMENT THERAPYSeptember 2021July 2024Allow3411YesNo
17486735Compositions and Methods Comprising a TTR Guide RNA and a Polynucleotide Encoding an RNA-Guided DNA Binding AgentSeptember 2021April 2025Abandon4211NoNo
17468086SYSTEMIC DELIVERY OF ADENO-ASSOCIATED VIRUS VECTOR EXPRESSING GAMMA-SARCOGLYCAN AND THE TREATMENT OF MUSCULAR DYSTROPHYSeptember 2021January 2024Allow2821NoNo
17461716CODON OPTIMIZED RPGRORF15 GENES AND USES THEREOFAugust 2021January 2022Allow500YesNo
17428401RECOMBINANT VECTORS SUITABLE FOR THE TREATMENT OF IPEX SYNDROMEAugust 2021November 2025Abandon5120YesNo
17368216BUDDING YEAST WITH HUMAN CHROMATINJuly 2021June 2023Allow2311YesNo
17365846SYNTHETIC DNA VECTORS AND METHODS OF USEJuly 2021February 2023Allow2021YesNo
17299024USE OF ACYL COENZYME A: CHOLESTEROL ACYLTRANSFERASE-1 IN DIAGNOSIS AND TREATMENT OF LIVER CANCERJune 2021October 2025Allow5221NoNo
17335500Programmable Cleavage of Double-Stranded DNAJune 2021March 2026Abandon5731NoYes
17244574GENE THERAPY VECTOR FOR TREATING RETINITIS PIGMENTOSA DISEASEApril 2021August 2023Allow2710YesNo
17289015USE OF NW_006883358.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEINApril 2021March 2026Abandon5820NoNo
17239540COMPOSITIONS, METHODS, MODULES AND INSTRUMENTS FOR AUTOMATED NUCLEIC ACID-GUIDED NUCLEASE EDITING IN MAMMALIAN CELLS USING MICROCARRIERSApril 2021October 2022Allow1831YesNo
17236556GENETIC DATA COMPRESSION AND METHODS OF USEApril 2021March 2025Allow4731YesNo
17230484COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERSApril 2021April 2023Allow2410NoNo
17279271METHOD FOR PROMOTING N-ACETYLGLUCOSAMINE SYNTHESIS BY USING GLCN6P RESPONSIVE ELEMENTMarch 2021December 2024Allow4510NoNo
17206522METHODS AND COMPOSITIONS FOR DIRECTED GENOME EDITINGMarch 2021October 2021Allow721YesNo
17273805COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEART DISEASEMarch 2021February 2026Abandon6021YesNo
17180741GENETIC TOOLBOX FOR METABOLIC ENGINEERING OF NON-CONVENTIONAL YEASTFebruary 2021June 2024Allow3920YesNo
17178737COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDESFebruary 2021January 2022Allow1121YesNo
17173137INCREASED NUCLEIC-ACID GUIDED CELL EDITING IN YEASTFebruary 2021October 2023Abandon3301NoNo
17158488ELECTROPORATION MODULES AND INSTRUMENTATIONJanuary 2021November 2021Allow921YesNo
17132694IDENTIFICATION OF SPATIAL BIOMARKERS OF HEART DISORDERS AND METHODS OF USING THE SAMEDecember 2020September 2024Abandon4521YesNo
16973894MATERIALS AND METHODS FOR MODULATING INTRAOCULAR AND INTRACRANIAL PRESSUREDecember 2020January 2026Abandon6021NoNo
17101299COMPOUNDS AND METHODS FOR MODULATING ANGIOTENSINOGEN EXPRESSIONNovember 2020October 2025Allow5911YesNo
17039575Cell-Free Expression System Having Novel Inorganic Polyphosphate-Based Energy RegenerationSeptember 2020November 2024Allow5031NoNo
17032657MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOFSeptember 2020September 2024Abandon4811NoNo
17040058CRISPR ASSOCIATED PROTEIN REACTIVE T CELL IMMUNITYSeptember 2020July 2025Abandon5821NoNo
16966682DRUG FOR CHRONIC INFLAMMATORY DISEASE AND METHOD FOR EVALUATING SUSCEPTIBILITY TO CHRONIC INFLAMMATORY DISEASEJuly 2020March 2024Abandon4411NoNo
16934970SYNTHETIC GENETIC ELEMENTS FOR BIOMANUFACTUREJuly 2020January 2024Allow4211NoNo
16933780CAPSID-MODIFIED RAAV VECTORS AND METHODS OF USEJuly 2020April 2025Abandon5720NoNo
16920051MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINSJuly 2020January 2024Abandon4310NoNo
16769522ENGINEERED UBIQUITOUS CHROMATIN OPENING ELEMENTS AND USES THEREOFJune 2020October 2023Abandon4010NoNo
16881871MODULATING EXPRESSION OF POLYPEPTIDES VIA NEW GENE SWITCH EXPRESSION SYSTEMSMay 2020October 2023Allow4120YesNo
16871736EXPRESSION CONSTRUCTS, HOST CELLS, AND METHODS FOR PRODUCING INSULINMay 2020April 2025Abandon5931NoNo
16756756METHODS AND COMPOSITIONS FOR TREATING AND PROTECTING AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUSApril 2020March 2024Allow4712YesNo
16846325Compositions and Methods for Inducing an Enhanced Immune Response Using Poxvirus VectorsApril 2020January 2026Allow6040YesNo
16842679AAV CAPSID DESIGNSApril 2020January 2025Abandon5750NoNo
16651779PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF HEART FAILUREMarch 2020September 2024Allow5421YesNo
16623052Demethylation of Reticuline and Derivatives Thereof with Fungal Cytochrome P450December 2019May 2023Allow4111YesNo
16685565PURIFICATION AND IDENTIFICATION OF A PROTEIN COMPLEX CONTAINING B-CELL LYMPHOMA PROTEIN (BCL10)November 2019November 2023Allow4821YesNo
16494645ADENO-ASSOCIATED VIRUS VECTOR DELIVERY OF A FRAGMENT OF MICRO-DYSTROPHIN TO TREAT MUSCULAR DYSTROPHYSeptember 2019January 2022Allow2810YesNo
16492878RIBOSWITCH MODULATED GENE THERAPY FOR RETINAL DISEASESSeptember 2019January 2024Allow5211YesNo
16563573UNIVERSAL DONOR CELLSSeptember 2019March 2025Allow6021YesNo
16512482Expression Constructs and Methods for Expressing Polypeptides in Eukaryotic CellsJuly 2019December 2024Abandon6011NoNo
16457528COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDESJune 2019July 2023Allow4921YesNo
16453260METHOD TO BUILD FUNGAL PRODUCTION STRAINS USING AUTOMATED STEPS FOR GENETIC MANIPULATION AND STRAIN PURIFICATIONJune 2019October 2022Abandon4041YesYes
16472793ADENO ASSOCIATED VIRAL VECTORSJune 2019March 2025Allow6011NoNo
16341504AAV CAPSID DESIGNSApril 2019September 2022Allow4221YesNo
16279688ADENO-ASSOCIATED VIRUS COMPOSITIONS FOR RESTORING F8 GENE FUNCTION AND METHODS OF USE THEREOFFebruary 2019December 2021Allow3411YesNo
16270198CONSTRUCTS AND METHODS FOR SIGNAL AMPLIFICATIONFebruary 2019August 2021Abandon3120NoNo
16322518Method for Producing Recombinant ProteinFebruary 2019February 2025Abandon6060YesNo
16320280BCL11A HOMING ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USEJanuary 2019June 2022Abandon4010NoNo
16252934NOVEL SACCHAROMYCES CEREVISIAE EXPRESSION SYSTEM AND CONSTRUCTION METHOD THEREOFJanuary 2019February 2022Abandon3721NoNo
16251970Gene Editing-based Method of Attenuating the Beta-Amyloid PathwayJanuary 2019July 2021Allow2920YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner HASAN, KHALEDA B.

Strategic Value of Filing an Appeal

Total Appeal Filings
5
Allowed After Appeal Filing
0
(0.0%)
Not Allowed After Appeal Filing
5
(100.0%)
Filing Benefit Percentile
0.6%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 0.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner HASAN, KHALEDA B - Prosecution Strategy Guide

Executive Summary

Examiner HASAN, KHALEDA B works in Art Unit 1636 and has examined 94 patent applications in our dataset. With an allowance rate of 54.3%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 48 months.

Allowance Patterns

Examiner HASAN, KHALEDA B's allowance rate of 54.3% places them in the 15% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by HASAN, KHALEDA B receive 2.26 office actions before reaching final disposition. This places the examiner in the 63% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by HASAN, KHALEDA B is 48 months. This places the examiner in the 7% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +57.2% benefit to allowance rate for applications examined by HASAN, KHALEDA B. This interview benefit is in the 96% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 16.0% of applications are subsequently allowed. This success rate is in the 12% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 51.4% of cases where such amendments are filed. This entry rate is in the 77% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Petition Practice

When applicants file petitions regarding this examiner's actions, 61.1% are granted (fully or in part). This grant rate is in the 65% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 1% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 7.8% of allowed cases (in the 86% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.