USPTO Examiner ZARA JANE J - Art Unit 1635

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18606473MRNA TREATMENT NANOPARTICLESMarch 2024September 2024Allow620NoNo
18408431COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNASJanuary 2024July 2024Allow610NoNo
18342806P21 MRNA TARGET AREAS FOR SILENCINGJune 2023March 2024Allow811NoNo
18316033SYNTHETIC SELF-AMPLIFYING MRNA MOLECULES WITH SECRETION ANTIGEN AND IMMUNOMODULATORMay 2023May 2024Allow1221YesNo
18181199RNAi Agents for Inhibiting Expression of DUX4, Compositions Thereof, And Methods of UseMarch 2023October 2023Allow710NoNo
18160804METHODS FOR USING TRANSCRIPTION-DEPENDENT DIRECTED EVOLUTION OF AAV CAPSIDSJanuary 2023April 2024Allow1421NoNo
18160796METHODS FOR USING TRANSCRIPTION-DEPENDENT DIRECTED EVOLUTION OF AAV CAPSIDSJanuary 2023April 2024Allow1521NoNo
18078821SIGNAL BOOST CASCADE ASSAYDecember 2022July 2023Allow812NoNo
18048390MRNA TREATMENT NANOPARTICLESOctober 2022August 2023Allow1010YesNo
17945842MULTI-CONJUGATE OF SIRNA AND PREPARING METHOD THEREOFSeptember 2022August 2023Allow1120NoNo
17945739CANCER TREATMENT USING siRNA TO MODULATE EXPRESSION OF PRDM2/RIZ PROTEINSeptember 2022February 2024Allow1711YesNo
17823586Methods Of Treating Metabolic Disorders And Cardiovascular Disease With Inhibin Subunit Beta E (INHBE) InhibitorsAugust 2022November 2023Allow1520NoNo
17823839METHOD OF STIMULATING PROLIFERATION OF A CELLAugust 2022September 2024Abandon2511NoNo
17850702LIPID NANOPARTICLE COMPOSITIONS AND METHODS OF FORMULATING THE SAMEJune 2022September 2022Allow310NoNo
17838984USE OF APTAMERS IN PROTEOMICSJune 2022November 2022Allow510YesNo
17826211COMPOSITIONS AND METHODS FOR INHIBITING MITOCHONDRIA AMIDOXIME REDUCING COMPONENT 1 (MARC1) EXPRESSIONMay 2022February 2023Allow901NoNo
17804192COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNASMay 2022December 2022Allow710NoNo
17825376NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF C3 IN A CELLMay 2022April 2023Allow1111NoNo
17747924DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDESMay 2022August 2023Allow1541YesNo
17740792MEDICAMENT USED FOR TREATING CHOLANGIOCARCINOMA WITH KRAS MUTATIONSMay 2022July 2024Abandon2711NoNo
17719580TREATMENT AND DETECTION OF INHERITED NEUROPATHIES AND ASSOCIATED DISORDERSApril 2022May 2024Allow2531YesNo
17711137Methods Of Treating Metabolic Disorders And Cardiovascular Disease With Inhibin Subunit Beta E (INHBE) InhibitorsApril 2022May 2023Allow1321NoNo
17709705Treatment of Liver Diseases With Cell Death Inducing DFFA Like Effector B (CIDEB) InhibitorsMarch 2022May 2023Allow1321NoNo
17709275COMPOSITIONS AND METHODS FOR TREATING SARS-COV-2 INFECTIONMarch 2022June 2023Allow1421NoNo
17709282METHODS FOR TREATING SARS-COV-2 INFECTIONMarch 2022January 2023Allow910NoNo
17671924LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOFFebruary 2022November 2022Allow910NoNo
17568757AGENT FOR USE IN THE TREATMENT OF GLIOMAJanuary 2022February 2024Allow2600NoNo
17560008Treatment of Liver Diseases With Cell Death Inducing DFFA Like Effector B (CIDEB) InhibitorsDecember 2021February 2024Allow2620NoNo
17548241CIRCULAR RNA COMPOSITIONS AND METHODSDecember 2021February 2023Allow1421NoNo
17519546MODIFICATIONS OF MAMMALIAN CELLS USING ARTIFICIAL MICRO-RNA TO ALTER THEIR PROPERTIES AND THE COMPOSITIONS OF THEIR PRODUCTSNovember 2021October 2022Allow1121YesNo
17513047Noninvasive Medical Procedure for Destruction of Cancer and Precancerous CellsOctober 2021August 2022Allow1011YesNo
17508786LIPID NANOPARTICLE COMPOSITIONS AND METHODS OF FORMULATING THE SAMEOctober 2021June 2022Allow711YesNo
17503208CIRCULAR RNA COMPOSITIONS AND METHODSOctober 2021January 2023Allow1521NoNo
17500410RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INDUCING DUX4 EXON SKIPPINGOctober 2021May 2024Allow3110YesNo
17450008MATERIALS AND METHODS FOR DELIVERING NUCLEIC ACIDS TO COCHLEAR AND VESTIBULAR CELLSOctober 2021May 2024Allow3210NoNo
17466448Usb1 Directed Regulation Of Mirnas Related Hematopoietic Differentiation And Affected In Multiple Forms Of LeukemiaSeptember 2021May 2024Allow3221NoNo
17466454Dosage Form for Treating Severe AsthmaSeptember 2021May 2024Allow3210NoNo
17461876METHODS FOR IDENTIFICATION OF GENETIC MODIFIERS AND FOR TREATING NUCLEOTIDE REPEAT DISORDERAugust 2021August 2023Abandon2301NoNo
17404249Compositions of DNA Molecules, Methods of Making Therefor, and Methods of Use ThereofAugust 2021August 2022Allow1211NoNo
17392170COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNASAugust 2021May 2022Allow910NoNo
17381024BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID SYNTHESISJuly 2021January 2024Allow3011YesNo
17417764Cell line with METTL3 gene knocked out, its construction method and interference vectorJune 2021January 2022Allow700NoNo
17348125METHODS OF TREATING BREAST CANCERJune 2021July 2024Abandon3801NoNo
17413387METHODS FOR IMPROVING EXERCISE TOLERANCE IN MYALGIC ENCEPHALOMYELITIS PATIENTSJune 2021August 2023Allow2610NoNo
17344920METHODS AND COMPOSITIONS FOR SYNTHESIS OF TWO-PHOTON CLEAVABLE PHOSPHORAMIDITE MOLECULES FOR OLIGONUCLEOTIDE CONJUGATIONJune 2021December 2023Allow3011NoNo
17337341METHODS FOR USING TRANSCRIPTION-DEPENDENT DIRECTED EVOLUTION OF AAV CAPSIDSJune 2021May 2022Allow1211YesNo
17325883RNA POLYMERASE VARIANTS FOR CO-TRANSCRIPTIONAL CAPPINGMay 2021April 2022Allow1120NoNo
17307846COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENEMay 2021August 2024Abandon4001NoNo
17243503iRNA AGENTS WITH BIOCLEAVABLE TETHERSApril 2021July 2024Abandon3910NoNo
17241920COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITYApril 2021February 2022Allow911NoNo
17225594RIG-I Agonists and Methods of Using SameApril 2021October 2022Abandon1930NoNo
17222772USE OF APTAMERS IN PROTEOMICSApril 2021May 2024Allow3810NoNo
17219000KIT, DEVICE, AND METHOD FOR DETECTING OVARIAN TUMORMarch 2021May 2024Allow3821YesNo
17279206ANTISENSE RNA TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH 1A DISEASEMarch 2021November 2023Allow3211NoNo
17202223CIRCULAR RNA COMPOSITIONS AND METHODSMarch 2021November 2022Allow2041YesNo
17188532COMPOUNDS AND THERAPEUTIC USES THEREOFMarch 2021June 2024Abandon3921YesNo
17181921COMPOSITIONS AND METHODS OF MODULATING HIF-2A TO IMPROVE MUSCLE GENERATION AND REPAIRFebruary 2021January 2024Allow3501NoNo
17172002GNAQ Targeted dsRNA Compositions and Methods for Inhibiting ExpressionFebruary 2021February 2024Allow3620NoNo
17170648COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENEFebruary 2021July 2024Abandon4111NoNo
17166985MICROSPHERE-BASED DELIVERY AND EX VIVO MANIPULATION OF DENDRITIC CELLS FOR AUTOIMMUNE THERAPIESFebruary 2021December 2023Abandon3510NoNo
17157803METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GLYCOLATE OXIDASE (HAO1) BY DOUBLE-STRANDED RNAJanuary 2021August 2023Allow3110NoNo
17263090NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF TMPRSS6 AND IRON CHELATORSJanuary 2021April 2024Allow3821YesNo
17155743SYNP161, A PROMOTER FOR THE EXPRESSION OF GENESJanuary 2021August 2023Allow3110NoNo
17147215COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSIONJanuary 2021January 2022Abandon1210NoNo
17145118FIDGETIN-LIKE 2 AS A TARGET TO ENHANCE WOUND HEALINGJanuary 2021February 2024Abandon3710NoNo
17142192OLIGONUCLEOTIDE CONSTRUCTS AND USES THEREOFJanuary 2021November 2023Abandon3501NoNo
17120973Modification of 3' Terminal Ends of Nucleic Acids by DNA Polymerase ThetaDecember 2020January 2024Allow3710NoNo
17252126CIRCULATING MIRNAS AS BIOMARKERS FOR DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT AND ALZHEIMERS DISEASEDecember 2020March 2024Allow3901NoNo
17103544MICRORNA PROFILING FOR DIAGNOSIS OF DYSPLASTIC NEVI AND MELANOMANovember 2020December 2023Allow3610NoNo
17095059NOVEL PHARMACEUTICAL COMPOSITION COMPRISING PARTICLES AND METHODS OF MAKING SAMENovember 2020September 2023Allow3410NoNo
17091422COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNASNovember 2020September 2023Allow3410NoNo
17084995METHODS OF MAKING NOVEL PHARMACEUTICAL COMPOSITIONSOctober 2020September 2023Allow3510NoNo
17084217COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND MIPOMERSEN AND METHODS OF USE THEREOFOctober 2020July 2023Allow3310NoNo
17080333METHOD FOR MODULATING GENE EXPRESSION BY MODIFYING THE CPG CONTENTOctober 2020July 2024Abandon4511NoNo
17080205Bicistronic AAV Vector for RNA Interference in ALSOctober 2020September 2023Allow3510NoNo
17075738METHOD OF TARGETING SENESCENT CELLSOctober 2020October 2023Allow3610NoNo
17027710Nucleic Acid Nanocapsules for Drug Delivery and Targeted Gene KnockdownSeptember 2020June 2023Allow3310NoNo
17012787BRANCHED OLIGONUCLEOTIDESSeptember 2020September 2023Allow3711NoNo
16978106NUCLEIC ACID MOLECULES AND METHODS OF USING THE SAMESeptember 2020September 2022Allow2431NoNo
17006588DEVELOPMENT OF POLYLYSINE:EPIGALLOCATECHIN-3-O-GALLATE AND DSRNA POLYPLEXES FOR CONTROL OF MOSQUITOESAugust 2020June 2023Allow3420NoNo
17003254TRANSGENIC MICROALGAE AND USE THEREOF AS A FEED FOR DELIVERY OF INTERFERING RNA MOLECULESAugust 2020October 2023Abandon3811NoNo
17000215CORONAVIRUS RNA VACCINESAugust 2020May 2021Allow911NoNo
16970845Targeting Cancer-Associated Long Non-Coding RNAsAugust 2020January 2023Allow2910NoNo
16995477NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEXAugust 2020February 2024Allow4211NoNo
16991192MEDICINE FOR TREATING DISORDERS OF GLUCOSE AND/OR LIPID METABOLISM AND A METHOD OF TREATING GLUCOSE AND/OR LIPID METABOLIC DISORDERSAugust 2020March 2023Allow3111NoNo
16968334Peptide Nucleic Acid Complex Having Endosomal Escape Capacity, And Use ThereofAugust 2020March 2023Abandon3211NoNo
16988395METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTSAugust 2020August 2022Allow2411NoNo
16983129USE OF SINGLE-STRANDED ANTISENSE OLIGONUCLEOTIDE IN PREVENTION OR TREATMENT OF GENETIC DISEASES INVOLVING A TRINUCLEOTIDE REPEAT EXPANSIONAugust 2020August 2023Abandon3601NoNo
16938474DNA GRIDIRON COMPOSITIONS AND METHODSJuly 2020April 2023Allow3310NoNo
16937386METHODS FOR REDUCING C9ORF72 EXPRESSIONJuly 2020May 2023Abandon3310NoNo
16962427NFAT BINDING POLYNUCLEOTIDESJuly 2020March 2022Abandon2011NoNo
16925545Aptamer Conjugates with N-Heterocyclic Carbene Metal Complexes for Targeted Drug DeliveryJuly 2020October 2023Allow3920NoNo
16923408USE OF LEUCINE-ZIPPER PROTEIN FOR DIAGNOSIS OR TREATMENT OF FATTY LIVERJuly 2020May 2022Allow2210NoNo
16959944SERUM RESPONSE FACTOR REGENERATES SENESCENT CELLSJuly 2020March 2024Allow4420NoNo
16958371ONCOLYTIC VIRAL DELIVERY OF THERAPEUTIC POLYPEPTIDESJune 2020August 2023Allow3811NoNo
16907678Treatment Of Decreased Bone Mineral Density With Zinc And Ring Finger 3 (ZNRF3) InhibitorsJune 2020March 2023Allow3311NoNo
16902717MATERIAL AND METHOD FOR COLORIMETRIC DETECTION OF SMALL-MOLECULE TARGETSJune 2020January 2021Allow710NoNo
16771323Modulation of Extracellular Vesicles with Electrical StimulationJune 2020February 2024Allow4431YesNo
16893253COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENEJune 2020February 2024Abandon4411NoNo
16888344DECREASING LACTATE LEVEL AND INCREASING POLYPEPTIDE PRODUCTION BY DOWNREGULATING THE EXPRESSION OF LACTATE DEHYDROGENASE AND PYRUVATE DEHYDROGENASE KINASEMay 2020March 2021Allow910YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner ZARA, JANE J.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
4
Examiner Affirmed
4
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.4%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
34
Allowed After Appeal Filing
7
(20.6%)
Not Allowed After Appeal Filing
27
(79.4%)
Filing Benefit Percentile
23.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 20.6% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner ZARA, JANE J - Prosecution Strategy Guide

Executive Summary

Examiner ZARA, JANE J works in Art Unit 1635 and has examined 765 patent applications in our dataset. With an allowance rate of 52.8%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 32 months.

Allowance Patterns

Examiner ZARA, JANE J's allowance rate of 52.8% places them in the 9% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by ZARA, JANE J receive 1.57 office actions before reaching final disposition. This places the examiner in the 41% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by ZARA, JANE J is 32 months. This places the examiner in the 30% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +21.4% benefit to allowance rate for applications examined by ZARA, JANE J. This interview benefit is in the 70% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 20.6% of applications are subsequently allowed. This success rate is in the 14% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 71.0% of cases where such amendments are filed. This entry rate is in the 91% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 66.7% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 50% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 75.0% of appeals filed. This is in the 59% percentile among all examiners. Of these withdrawals, 91.7% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 49.0% are granted (fully or in part). This grant rate is in the 58% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 5.0% of allowed cases (in the 89% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 3.5% of allowed cases (in the 74% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.