USPTO Examiner WHITEMAN BRIAN A - Art Unit 1635

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17132448SYNTHETIC RIG-I-LIKE RECEPTOR AGONISTSDecember 2020December 2023Allow3621NoNo
17128320APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOFDecember 2020May 2021Allow410NoNo
17127664P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATIONDecember 2020May 2024Allow4110NoNo
17125245METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF COMPLEMENT COMPONENT 5(C5) BY DOUBLE-STRANDED RNADecember 2020April 2023Allow2810NoNo
17116214COMPOSITIONS AND METHODS FOR TARGETING GLYPICAN-2 IN THE TREATMENT OF CANCERDecember 2020January 2023Abandon2601NoNo
17247265Nucleic Acid Molecules and Uses ThereofDecember 2020October 2023Allow3411NoNo
16949980MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHYNovember 2020May 2024Allow4210NoNo
17055888AAV SEROTYPES FOR BRAIN SPECIFIC PAYLOAD DELIVERYNovember 2020April 2024Abandon4101NoNo
17097695METHODS AND COMPOSITIONS FOR INHIBITING NECROPTOSIS IN NEUROVASCULAR AND/OR NEURODEGENERATIVE DISEASES OR DISORDERSNovember 2020November 2023Abandon3621NoNo
17094724NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERYNovember 2020June 2023Abandon3110NoNo
17053193MATERIALS AND METHODS FOR THE DELIVERY OF THERAPEUTIC NUCLEIC ACIDS TO TISSUESNovember 2020September 2022Allow2321NoNo
17052610FUNCTIONAL LIGANDS TO DICAMBANovember 2020January 2023Abandon2701NoNo
17085319GIN RECOMBINASE VARIANTSOctober 2020July 2023Allow3210NoNo
17080771RNAi Constructs for Inhibiting ASGR1 Expression and Methods of Use ThereofOctober 2020March 2023Allow2811NoNo
17049041MICRORNAS AS THERAPEUTIC TARGETS FOR ISCHEMIC STROKEOctober 2020November 2022Allow2521YesNo
17048466tRNA/pre-miRNA Compositions and Methods For Treating Hepatocellular CarcinomaOctober 2020May 2023Allow3010NoNo
17047978MRNA Driven Expression of RNA Editors for Treatment of PathologiesOctober 2020June 2023Allow3221YesNo
17070337FN3 Domain-siRNA Conjugates and Uses ThereofOctober 2020May 2023Allow3111NoNo
17067572MICRORNA REGULATED EXPRESSION VECTORS, METHODS OF MAKING, AND USES THEREOFOctober 2020April 2024Abandon4201NoNo
17046478MIRNAS FOR TREATMENT AND IN VITRO DIAGNOSIS OF DRUG RESISTANT TUMORSOctober 2020July 2022Allow2221YesNo
17063610USE OF FUBP1 INHIBITORS FOR TREATING HEPATITIS B VIRUS INFECTIONOctober 2020March 2023Allow2921NoNo
17043784APTAMERS FOR TARGETED ACTIVATION OF T CELL-MEDIATED IMMUNITYSeptember 2020January 2024Allow4011YesNo
17044028METHODS OF MODULATING NKX6.3September 2020May 2022Abandon2001NoNo
17044237Systems, Methods And Composition of Using RNASE III Mutants to Produce sRNA to Control Host Pathogen InfectionSeptember 2020January 2023Allow2811YesNo
17032259MICRORNA-BASED LOGIC GATES AND USES THEREOFSeptember 2020June 2022Allow2111YesNo
17024100OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNASeptember 2020June 2023Allow3320NoNo
17022984APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOFSeptember 2020October 2022Allow2500NoNo
17019183COMPOSITIONS AND METHODS FOR CHARACTERIZING A MICROBIOMESeptember 2020November 2021Allow1421YesNo
17019154SYSTEMS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIESSeptember 2020February 2024Allow4121YesNo
16979777MICRO-RNA AND OBESITYSeptember 2020April 2023Allow3120NoNo
16978778APPLICATION OF MICRORNA-210 INHIBITOR IN PREPARATION OF DRUGS FOR TREATING INFLAMMATORY SKIN DISEASESSeptember 2020September 2022Allow2511NoNo
16977152COMPOSITIONS AND METHODS FOR INHIBITING GYS2 EXPRESSIONSeptember 2020September 2022Allow2521YesNo
17006003Methods of Treating Wounds Using Cathepsin K InhibitorsAugust 2020June 2023Allow3320NoNo
16971893SHORT/SMALL HAIRPIN RNA MOLECULESAugust 2020April 2024Allow4451YesNo
16999948IMMUNOTHERAPEUTIC CONSTRUCTS AND METHODS OF THEIR USEAugust 2020September 2021Allow1321YesNo
16996616METHODS FOR TREATING BRAIN INJURYAugust 2020January 2023Allow2910NoNo
16995586MICRO-RNA PROFILING, COMPOSITIONS, AND METHODS OF TREATING DISEASESAugust 2020April 2022Allow2010NoNo
16988391MODIFIED OLIGONUCLEOTIDES TARGETING SNPsAugust 2020October 2023Allow3821YesYes
16966132THERAPEUTIC AGENT FOR GLYCOGEN STORAGE DISEASE TYPE IAJuly 2020July 2023Allow3621YesNo
16941028TREATMENT OF PRIMARY CILIARY DYSKINESIA WITH SYNTHETIC MESSENGER RNAJuly 2020November 2022Allow2710YesNo
16963914METHODS OF TREATING SPINAL MUSCULAR ATROPHYJuly 2020June 2022Allow2311NoNo
16963772Method to enhance the transcription regulation of SUPT4H on genes containing repetitive nucleotide sequencesJuly 2020September 2023Allow3831YesNo
16963315HIGH EFFICIENCY APTAMER COMPLEX COMPRISING BRANCHED DNA AND APTAMER, AND USE THEREOFJuly 2020June 2022Allow2311NoNo
16961062METHODS FOR PREVENTING GRAFT ISCHEMIA REPERFUSION INJURY DURING EX VIVO MACHINE PERFUSION PRESERVATIONJuly 2020February 2024Allow4311NoNo
16631954miRNA AS BIOMARKER FOR PARKINSON'S DISEASE AND DIAGNOSTIC KIT USING SAMEJune 2020May 2022Allow2821YesNo
16910237SYSTEMIC DELIVERY OF MYOSTATIN SHORT INTERFERING NUCLEIC ACIDS (SINA) CONJUGATED TO A LIPOPHILIC MOIETYJune 2020May 2022Allow2310NoNo
16908798AAV-BASED TREATMENT OF CHOLESTEROL-RELATED DISORDERSJune 2020April 2022Allow2210NoNo
16908313METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASYMMETRIC DOUBLE-STRANDED RNAJune 2020May 2022Allow2321NoNo
16956092NUCLEIC ACID CONSTRUCT FOR IN VITRO AND IN VIVO GENE EXPRESSIONJune 2020October 2022Allow2820NoNo
16902316METHODS RELATING TO CIRCULATING TUMOR CELL CLUSTERS AND THE TREATMENT OF CANCERJune 2020April 2022Allow2221NoNo
16898849ApoCIII and the Treatment and Diagnosis of DiabetesJune 2020December 2021Abandon1811NoNo
16897549COMPOSITIONS AND METHODS FOR XI CHROMOSOME REACTIVATIONJune 2020October 2021Allow1721NoNo
16897976OLIGONUCLEOTIDE PROBES AND USES THEREOFJune 2020January 2022Allow1910NoNo
16770478SENILE DEMENTIA TREATMENT FORMULATION AND APPLICATION THEREOFJune 2020July 2022Allow2521YesNo
16890436GLOBIN GENE THERAPY FOR TREATING HEMOGLOBINOPATHIESJune 2020April 2023Allow3411NoNo
16889372METHOD FOR DETERMINING DECREASE IN FUNCTIONS OF HIPPOCAMPUS BY USING CORRELATION BETWEEN MICRO RNA AND NMDA RECEPTOR, METHOD FOR INHIBITING DECREASE IN FUNCTIONS, AND METHOD FOR SCREENING FOR INHIBITORS OF DECREASE IN FUNCTIONSJune 2020March 2022Allow2220YesNo
16889470MODULATION OF TRANSTHYRETIN EXPRESSIONJune 2020August 2022Allow2711NoNo
16764640KISSPEPTIN 1 (KISS1) IRNA COMPOSITIONS AND METHODS OF USE THEREOFMay 2020August 2022Abandon2711NoNo
16764307NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOFMay 2020March 2022Allow2211NoNo
16763880RUNX1 INHIBITION FOR TREATMENT OF PROLIFERATIVE VITREORETINOPATHY AND CONDITIONS ASSOCIATED WITH EPITHELIAL TO MESENCHYMAL TRANSITIONMay 2020April 2023Allow3521NoNo
15930377RNA INTERFERENCE IN OCULAR INDICATIONSMay 2020October 2022Allow2910NoNo
16870766CMV VECTORS COMPRISING MICRORNA RECOGNITION ELEMENTSMay 2020November 2022Abandon3020NoNo
16867587DETECTION OF MICROBIAL ENDOTOXINS IN ORAL SAMPLES USING APTAMERSMay 2020January 2023Allow3211NoNo
16761880APTAMER FOR ADAMTS5 AND USE FOR APTAMER FOR ADAMTS5May 2020July 2022Allow2610NoNo
16867763FMRP and Cancer TreatmentMay 2020May 2022Allow2521NoNo
16761009METHODS AND COMPOSITIONS RELATED TO INCREASED ROTAVIRUS PRODUCTIONMay 2020June 2023Abandon3811NoNo
16761112COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHYMay 2020April 2023Abandon3621NoNo
16756988METHODS OF EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE CONE PHOTORECEPTORS OF A SUBJECT COMPRISING THE SUBRETINAL DELIVERY OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A RECOMBINANT AAV9-DERIVED VECTORApril 2020March 2023Allow3511NoNo
16850355APTAMERS BINDING TO LEGIONELLA PNEUMOPHILAApril 2020February 2022Allow2210NoNo
16850555MODIFIED RNAi AGENTSApril 2020March 2022Allow2320NoNo
16756298CONTROL OF PLANT PESTS USING RNA MOLECULESApril 2020August 2021Allow1621YesNo
16756232CONTROL OF PLANT PESTS USING RNA MOLECULESApril 2020February 2024Allow4651YesNo
16848273CD133 RELATED TO ANTICANCER AGENT RESISTANCE IN COLON CANCER AND USE THEREOFApril 2020December 2022Allow3211NoNo
16842157ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSISApril 2020November 2021Allow1910NoNo
16840249OLIGONUCLEOTIDES FOR MODULATING ATXN2 EXPRESSIONApril 2020November 2021Allow1910YesNo
16650496CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRANSCRIPTIONMarch 2020July 2023Allow4021NoNo
16649244COMPOSITIONS AND METHODS OF TREATING HUNTINGTON'S DISEASEMarch 2020July 2022Allow2800NoNo
16825918Thiomorpholino Oligonucleotides For The Treatment of Muscular DystrophyMarch 2020August 2022Allow2911NoNo
16825284DNA APTAMERS, METHOD FOR INHIBITING HUMAN GALECTIN-1 AND METHOD OF TREATING A MAMMAL IN NEED THEREOFMarch 2020January 2023Allow3411NoNo
16648822SPLICE INHIBITING OLIGONUCLEOTIDESMarch 2020April 2021Allow1311NoNo
16814398PREDICTING RESPONSE TO ALVOCIDIB BY MITOCHONDRIAL PROFILINGMarch 2020January 2022Abandon2210NoNo
16811504COMPOSITIONS AND PROCESSES FOR TARGETED DELIVERY, EXPRESSION AND MODULATION OF CODING RIBONUCLEIC ACIDS IN TISSUEMarch 2020May 2022Allow2631YesYes
16810771POLYNUCLEOTIDE CONJUGATES AND USES THEREOFMarch 2020August 2022Abandon3011NoNo
16807577TARGETED RNA EDITINGMarch 2020March 2023Allow3620NoNo
16643293AN INHIBITOR FOR USE FOR PREVENTING AND/OR TREATING AN INFECTION WITH HEPATITIS B VIRUSFebruary 2020August 2022Allow3030NoNo
16798314FUNCTIONAL LIGANDS TO COLISTINFebruary 2020November 2022Allow3311NoNo
16640856METHODS OF CHANGING TRANSCRIPTIONAL OUTPUTFebruary 2020July 2022Abandon2901NoNo
16640213MODIFIED POLYNUCLEOTIDEFebruary 2020September 2021Allow1921YesNo
16794066COMPOSITIONS AND METHODS FOR TREATING HEPATIC FIBROSISFebruary 2020October 2021Allow2021YesNo
16789483METHOD FOR DETERMINING DESIRED CELL TYPE USING EXPRESSION OF miRNA AS INDICATORFebruary 2020December 2021Abandon2210NoNo
16786709RNA CONTAINING COMPOSITIONS AND METHODS OF THEIR USEFebruary 2020January 2024Abandon4730NoNo
16636255TUNABLE REVERSIR TM COMPOUNDSFebruary 2020March 2022Abandon2501NoNo
16778582RNAI AGENTS FOR INHIBITING EXPRESSION OF ALPHA-ENAC AND METHODS OF USEJanuary 2020August 2021Allow1911NoNo
16778188RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)January 2020August 2021Allow1911NoNo
16777742MULTI-TARGET MODULATION FOR TREATING FIBROSIS AND INFLAMMATORY CONDITIONSJanuary 2020October 2021Abandon2011NoNo
16750083RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)January 2020January 2022Allow2311NoNo
16749293MODULATORY POLYNUCLEOTIDESJanuary 2020August 2021Allow1810NoNo
16746555DYNAMIC PHARMACOKINETIC-MODIFYING ANCHORSJanuary 2020June 2022Allow2931NoNo
16631866PRESYMPTOMATIC MICRO RNA TARGETS FOR TREATMENT OF NEURODEGENERATION PATHOLOGYJanuary 2020March 2021Allow1421YesNo
16742741COMPOSITIONS AND METHODS FOR INHIBITING FACTOR DJanuary 2020December 2021Allow2310NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner WHITEMAN, BRIAN A.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
7
Examiner Affirmed
7
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.6%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
70
Allowed After Appeal Filing
3
(4.3%)
Not Allowed After Appeal Filing
67
(95.7%)
Filing Benefit Percentile
11.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 4.3% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner WHITEMAN, BRIAN A - Prosecution Strategy Guide

Executive Summary

Examiner WHITEMAN, BRIAN A works in Art Unit 1635 and has examined 783 patent applications in our dataset. With an allowance rate of 52.7%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 30 months.

Allowance Patterns

Examiner WHITEMAN, BRIAN A's allowance rate of 52.7% places them in the 16% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by WHITEMAN, BRIAN A receive 1.72 office actions before reaching final disposition. This places the examiner in the 34% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by WHITEMAN, BRIAN A is 30 months. This places the examiner in the 58% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +23.2% benefit to allowance rate for applications examined by WHITEMAN, BRIAN A. This interview benefit is in the 68% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 28.3% of applications are subsequently allowed. This success rate is in the 54% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 56.8% of cases where such amendments are filed. This entry rate is in the 84% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 200.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 93% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences are highly effective with this examiner compared to others. Before filing a full appeal brief, strongly consider requesting a PAC. The PAC provides an opportunity for the examiner and supervisory personnel to reconsider the rejection before the case proceeds to the PTAB.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 74.1% of appeals filed. This is in the 63% percentile among all examiners. Of these withdrawals, 95.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 66.4% are granted (fully or in part). This grant rate is in the 70% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 4.9% of allowed cases (in the 86% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 3.9% of allowed cases (in the 79% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Request pre-appeal conferences: PACs are highly effective with this examiner. Before filing a full appeal brief, request a PAC to potentially resolve issues without full PTAB review.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.