USPTO Examiner KONOPKA CATHERINE ANNE - Art Unit 1635

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19054630COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSIONFebruary 2025April 2025Allow200YesNo
19027181Compositions for Inducing Modifications of Target Endogenous Nucleic Acid Sequences in Nucleuses of Eukaryotic CellsJanuary 2025November 2025Allow1010YesNo
19023934Compositions for Inducing Modifications of Target Endogenous Nucleic Acid Sequences in Nucleuses of Eukaryotic CellsJanuary 2025March 2026Allow1410YesNo
19007236COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSIONDecember 2024March 2025Allow300YesNo
19002832Compositions for Inducing Modifications of Target Endogenous Nucleic Acid Sequences in Nucleuses of Eukaryotic CellsDecember 2024October 2025Allow1010YesNo
18970575BASE EDITOR AND THE USE THEREOFDecember 2024December 2025Allow1220YesNo
18932745COMPOSITIONS FOR INDUCING MODIFICATIONS OF TARGET ENDOGENOUS NUCLEIC ACID SEQUENCES IN NUCLEUSES OF EUKARYOTIC CELLSOctober 2024August 2025Allow1020YesNo
18820460CRISPR-CAS SYSTEMS AND USES THEREOFAugust 2024July 2025Allow1120YesNo
18755750CRISPR-CAS13 SYSTEM AND USE THEREOFJune 2024January 2025Allow710YesNo
18607210GUIDED MICROBIAL REMODELING, A PLATFORM FOR THE RATIONAL IMPROVEMENT OF MICROBIAL SPECIES FOR AGRICULTUREMarch 2024November 2025Allow2011YesNo
18408504Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene CorrectionJanuary 2024January 2026Abandon2510NoNo
18406053COMBINATORIAL TARGETED THERAPY METHODSJanuary 2024February 2025Allow1320YesNo
18543827MODIFIED NUCLEIC ACIDS, HYBRID GUIDE RNAS, AND USES THEREOFDecember 2023February 2025Allow1410YesNo
18537662Allosteric Conditional Guide RNAs for Cell-Selective Regulation of CRISPR/CasDecember 2023April 2025Allow1610YesNo
18520878SYSTEMS AND METHODS FOR TARGETED INTEGRATION AND GENOME EDITING AND DETECTION THEREOF USING INTEGRATED PRIMING SITESNovember 2023March 2025Abandon1601NoNo
18488109MODULAR DNA-BINDING DOMAINS AND METHODS OF USEOctober 2023October 2025Allow2411YesNo
18374673METHODS FOR IMPROVED HOMOLOGOUS RECOMBINATION AND COMPOSITIONS THEREOFSeptember 2023October 2025Allow2521YesNo
18477291COMPOSITIONS FOR GENOME EDITINGSeptember 2023December 2025Allow2621YesNo
18552549AAV-IDS VECTORS FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS IISeptember 2023March 2026Allow2900YesNo
18467297METHOD FOR PRODUCING DNA-EDITED EUKARYOTIC CELL, AND KIT USED IN THE SAMESeptember 2023April 2025Allow1920NoNo
18467356METHOD FOR PRODUCING DNA-EDITED EUKARYOTIC CELL, AND KIT USED IN THE SAMESeptember 2023October 2025Abandon2520NoNo
18460058gRNA STABILIZATION IN NUCLEIC ACID-GUIDED NICKASE EDITINGSeptember 2023October 2025Abandon2521NoNo
18452508COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VIRUS THROUGH TARGETED GENE REPRESSIONAugust 2023November 2024Allow1520YesNo
18219524BIOCONTAINMENT/BIOCONTROL SYSTEM AND METHODSJuly 2023May 2025Allow2200YesNo
18345653GENE EDITINGJune 2023June 2025Abandon2410NoNo
18334046TYPE VI CRISPR ORTHOLOGS AND SYSTEMSJune 2023December 2025Allow3040YesNo
18332029COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITINGJune 2023October 2025Allow2921YesNo
18127853CRISPR-CAS BASED SYSTEM FOR TARGETING SINGLE-STRANDED SEQUENCESMarch 2023August 2025Abandon2910NoNo
18114112ADMINISTRATION REGIMEFebruary 2023July 2025Abandon2910NoNo
18166746A HTP PLATFORM FOR THE GENETIC ENGINEERING OF CHINESE HAMSTER OVARY CELLSFebruary 2023June 2025Abandon2810NoNo
18104640METHODS AND KITS FOR IDENTIFYING CANCER TREATMENT TARGETSFebruary 2023December 2024Allow2310NoNo
18068061DNA EDITING USING SINGLE-STRANDED DNADecember 2022September 2025Abandon3321NoNo
18064011METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA DIRECTED MODULATION OF TRANSCRIPTIONDecember 2022December 2024Abandon2401NoNo
17999341HDR ENHANCERSNovember 2022March 2026Abandon4010NoNo
17926208USE OF A DEFICIENT FUSION PROTEIN FOR NUCLEASE ACTIVITY SO AS TO INDUCE MEIOTIC RECOMBINATIONSNovember 2022February 2026Allow3910YesNo
18054538METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONNovember 2022December 2024Abandon2501NoNo
17911646FNCPF1 MUTANT FOR BROAD-SPECTRUM IDENTIFICATION ON PAM SEQUENCE ANS USE THEREOFSeptember 2022November 2025Allow3810YesNo
17931018RNA GUIDED COMPOSITIONS FOR PREVENTING AND TREATING HEPATITIS B VIRUS INFECTIONSSeptember 2022March 2025Abandon3010NoNo
17930079In Vitro Cleavage of DNA Using ArgonauteSeptember 2022July 2025Allow3421YesNo
17823076MIR-149-3P AND METHOD FOR TREATING METABOLIC DISEASE USING THE SAMEAugust 2022November 2025Abandon3901NoNo
17794263CONSTRUCTION OF HIGH-FIDELITY CRISPR/ASCPF1 MUTANT AND USES THEREOFJuly 2022December 2025Allow4010YesNo
17757289LONG NON-CODING RNA LETN SERVING AS TUMOR MARKER AND THERAPEUTIC TARGET POINTJune 2022December 2025Allow4211YesNo
17750116ALTERING MICROBIAL POPULATIONS & MODIFYING MICROBIOTAMay 2022April 2025Abandon3540YesYes
17749017RNA-GUIDED NUCLEIC ACID MODIFYING ENZYMES AND METHODS OF USE THEREOFMay 2022November 2024Allow3010YesNo
17744475COMPOSITIONS AND METHODS OF TREATMENT FOR LYTIC AND LYSOGENIC VIRUSESMay 2022May 2025Abandon3611NoNo
17775490SELECTION MARKER FREE METHODS FOR MODIFYING THE GENOME OF BACILLUS AND COMPOSITIONS THEREOFMay 2022November 2025Allow4210YesNo
17770512LIGHT-INDUCIBLE CRISPR/CAS9 SYSTEM FOR GENOME EDITINGApril 2022November 2025Allow4310YesNo
17762591A PROMOTER SPECIFIC FOR NON-PIGMENTED CILIARY EPITHELIAL CELLSMarch 2022October 2025Allow4310YesNo
17639043MODIFIED BACTERIAL RETROELEMENT WITH ENHANCED DNA PRODUCTIONFebruary 2022January 2025Abandon3410NoNo
17588289YAP1 Gene-Modified Mesenchymal Stem Cell and Preparation Method ThereofJanuary 2022December 2025Abandon4610NoNo
17559860METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONDecember 2021November 2024Allow3410NoNo
17514919METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021August 2025Abandon4501NoNo
17514936METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021November 2025Abandon4901NoNo
17514929METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021October 2025Abandon4801NoNo
17514893METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021June 2025Abandon4401NoNo
17514908METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021July 2025Abandon4401NoNo
17514883METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021July 2025Abandon4401NoNo
17514940METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONOctober 2021November 2025Abandon4901NoNo
17436208HIGH-THROUGHPUT GENE-EDITING TECHNIQUEOctober 2021December 2025Abandon5220NoNo
17605214TAILORED HYPOIMMUNE NANOVESICULAR DELIVERY SYSTEMS FOR CANCER TUMORSOctober 2021March 2025Allow4110YesNo
17604119HIGH-THROUGHPUT METHODS FOR ISOLATING AND CHARACTERIZING AMMONIUM-EXCRETING MUTANT LIBRARIES GENERATED BY CHEMICAL MUTAGENESISOctober 2021October 2025Allow4821NoNo
17481056TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USESeptember 2021September 2025Abandon4801NoNo
17593556GENETIC RISK ANALYSIS FOR POST-TRAUMATIC STRESS DISORDERS AND BEHAVIORAL MANAGEMENT THEREOFSeptember 2021November 2025Abandon4901NoNo
17436510ENHANCED HUMAN OPSIN PROMOTER FOR ROD SPECIFIC EXPRESSIONSeptember 2021December 2025Allow5230YesNo
17433927COMPOSITIONS AND METHODS FOR TREATING LAMINOPATHIESAugust 2021April 2025Allow4310YesNo
17407928COMPOSITIONS AND METHODS OF NUCLEIC ACID-TARGETING NUCLEIC ACIDSAugust 2021December 2025Allow5150YesNo
17430665COMPOSITIONS AND METHODS FOR TREATING ALPHA-1 ANTITRYPSIN DEFICIENCYAugust 2021November 2025Allow5121YesNo
17430298COMPOSITIONS AND METHODS FOR TREATING HEMOGLOBINOPATHIESAugust 2021July 2025Allow4811YesNo
17427410NUCLEOBASE EDITORS HAVING REDUCED NON-TARGET DEAMINATION AND ASSAYS FOR CHARACTERIZING NUCLEOBASE EDITORSJuly 2021August 2025Allow4920NoNo
17388321TYPE V CRISPR/CAS EFFECTOR PROTEINS FOR CLEAVING SSDNAS AND DETECTING TARGET DNASJuly 2021February 2025Allow4220NoNo
17425876MITOCHONDRIAL GENOME EDITING METHODSJuly 2021July 2025Allow4820YesNo
17348619METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONJune 2021August 2024Allow3810YesNo
17348596METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTIONJune 2021August 2024Allow3810YesNo
17294175CRISPR/CAS12J ENZYME AND SYSTEMMay 2021June 2025Allow4911YesNo
17246081CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING CYSTIC FIBROSISApril 2021February 2025Abandon4611NoNo
17284660METHODS AND KITS FOR IDENTIFYING CANCER TREATMENT TARGETSApril 2021February 2025Allow4611YesNo
17269958BIOMARKER FOR MYALGIC ENCEPHALOMYELITIS/CHRONIC FATIGUE SYNDROME (ME/CFS)February 2021February 2025Abandon4820NoNo
17262782BIOSENSORS FOR DETECTING ARRESTIN SIGNALINGJanuary 2021August 2025Allow5421YesNo
17054938MIRI26-5P FOR TREATING MOTOR NEURON DISEASESNovember 2020March 2026Allow6041YesNo
16999649CLEAVAGE-RESISTANT DONOR NUCLEIC ACIDS AND METHODS OF USEAugust 2020November 2024Abandon5141NoNo
16992815EXTRACHROMOSOMAL DNA LABELINGAugust 2020December 2025Allow6041YesYes
16913299RNA-GUIDED DNA INTEGRATION USING TN7-LIKE TRANSPOSONSJune 2020February 2025Allow5510YesNo
16865129COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCESMay 2020March 2025Abandon5961YesNo
16644445METHODS FOR IMPROVED HOMOLOGOUS RECOMBINATION AND COMPOSITIONS THEREOFMarch 2020February 2025Abandon5921NoNo
16698276METHODS AND COMPOSITIONS FOR MODIFYING A SINGLE STRANDED TARGET NUCLEIC ACIDNovember 2019December 2024Abandon6030YesNo
16463883GENOME EDITING METHODOctober 2019January 2025Abandon6060NoNo
16603377Compounds for Increasing Genome Editing EfficiencyOctober 2019August 2024Allow5841YesNo
16499889Method of Recording Multiplexed Biological Information into a CRISPR Array Using a RetronOctober 2019August 2025Abandon6040NoNo
16486799GENE EDITING THERAPY FOR HIV INFECTION VIA DUAL TARGETING OF HIV GENOME AND CCR5August 2019April 2025Abandon6042NoYes
16482294Methods for Increasing Efficiency of Gene Editing in CellsJuly 2019April 2025Allow6061YesNo
16469098COMPOSITIONS AND METHODS FOR CRISPR-BASED SCREENINGJune 2019March 2025Abandon6021NoNo
16417499Methods for mitochondria and organelle genome editingMay 2019February 2025Abandon6041NoNo
16343987MODULAR EXTRACELLULAR SENSOR ARCHITECTURE FOR REGULATING GENESApril 2019May 2025Allow6061YesNo
16341025NANOPARTICLES FUNCTIONALIZED WITH GENE EDITING TOOLS AND RELATED METHODSApril 2019November 2024Abandon6041NoNo
16326908SINGLE GUIDE RNA/CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOFFebruary 2019November 2024Abandon6031NoNo
16100040METHODS AND COMPOSITIONS FOR ATTENUATING GENE EXPRESSION MODULATING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSESAugust 2018January 2025Abandon6031NoYes
16040204METHYLENE-TETRAHYDROFOLATE REDUCTASE ISOFORM-BASED BIOMARKER AND METHOD OF USE THEREOFJuly 2018September 2024Allow6051YesNo
15769180EXPRESSION IN MAMMALIAN CELLS WITH GAUSSIA LUCIFERASE SIGNAL PEPTIDEApril 2018August 2024Allow6081YesNo
15335139NUCLEIC ACID ENRICHMENT USING CAS9October 2016May 2025Abandon6091NoYes
14897213ANALYSIS OF POLYNUCLEOTIDESDecember 2015June 2025Allow60101YesYes

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner KONOPKA, CATHERINE ANNE.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
1
Examiner Affirmed
1
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.5%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
6
Allowed After Appeal Filing
0
(0.0%)
Not Allowed After Appeal Filing
6
(100.0%)
Filing Benefit Percentile
0.5%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 0.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner KONOPKA, CATHERINE ANNE - Prosecution Strategy Guide

Executive Summary

Examiner KONOPKA, CATHERINE ANNE works in Art Unit 1635 and has examined 50 patent applications in our dataset. With an allowance rate of 50.0%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 51 months.

Allowance Patterns

Examiner KONOPKA, CATHERINE ANNE's allowance rate of 50.0% places them in the 12% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by KONOPKA, CATHERINE ANNE receive 2.70 office actions before reaching final disposition. This places the examiner in the 79% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by KONOPKA, CATHERINE ANNE is 51 months. This places the examiner in the 4% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +76.5% benefit to allowance rate for applications examined by KONOPKA, CATHERINE ANNE. This interview benefit is in the 99% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 14.0% of applications are subsequently allowed. This success rate is in the 9% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 22.2% of cases where such amendments are filed. This entry rate is in the 28% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 66.7% of appeals filed. This is in the 47% percentile among all examiners. Of these withdrawals, 100.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows below-average willingness to reconsider rejections during appeals. Be prepared to fully prosecute appeals if filed.

Petition Practice

When applicants file petitions regarding this examiner's actions, 50.0% are granted (fully or in part). This grant rate is in the 46% percentile among all examiners. Strategic Note: Petitions show below-average success regarding this examiner's actions. Ensure you have a strong procedural basis before filing.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 1% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 8.0% of allowed cases (in the 86% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.