USPTO Examiner LEAVITT MARIA GOMEZ - Art Unit 1633

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17254157ENERGETIC CANCER STEM CELLS (E-CSCS): A NEW HYPER-METABOLIC AND PROLIFERATIVE TUMOR CELL PHENOTYPE, DRIVEN BY MITOCHONDRIAL ENERGYDecember 2020April 2022Allow1620YesNo
17009410GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC LAG3September 2020September 2022Allow2440YesNo
17003081MODIFIED CELLS AND METHODS OF THERAPYAugust 2020January 2023Allow2870YesNo
16996103ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAMEAugust 2020April 2021Allow811YesNo
16983937Antigen Discovery for T Cell Receptors Isolated from Patient Tumors Recognizing Wild-Type Antigens and Potent Peptide MimotopesAugust 2020October 2021Abandon1420NoNo
16924950ENGINEERED REGULATORY T CELLSJuly 2020July 2021Allow1321YesNo
16958649ENHANCED IMMUNE CELLS USING DUAL SHRNA AND COMPOSITION INCLUDING THE SAMEJune 2020February 2023Allow3131YesNo
16904451T CELL-ANTIGEN COUPLER WITH VARIOUS CONSTRUCT OPTIMIZATIONSJune 2020June 2021Allow1221YesNo
16881668BCMA-TARGETED CHIMERIC ANTIGEN RECEPTOR AS WELL AS PREPARATION METHOD THEREFOR AND APPLICATION THEREOFMay 2020July 2021Allow1410YesNo
15929513T CELL-ANTIGEN COUPLER WITH VARIOUS CONSTRUCT OPTIMIZATIONSMay 2020June 2021Allow1321YesNo
16864689CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEINMay 2020December 2021Abandon1930NoNo
16818211TREATING CANCER WITH CAS ENDONUCLEASE COMPLEXESMarch 2020November 2023Abandon4451NoNo
16631437SINGLE CHAIN VH AND HEAVY CHAIN ANTIBODIESJanuary 2020March 2022Allow2621YesNo
16742723CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEINJanuary 2020September 2021Abandon2021NoNo
16709147DELIVERY OF PACKAGED RNA TO MAMMALIAN CELLSDecember 2019December 2023Abandon4810NoNo
16707807QUADRICISTRONIC SYSTEM COMPRISING A HOMING RECEPTOR AND CHIMERIC ANTIGEN RECEPTOR FOR STABLE GENETIC MODIFICATION OF CELLULAR IMMUNOTHERAPIESDecember 2019July 2021Allow1940YesNo
16708082QUADRICISTRONIC SYSTEM COMPRISING A HOMING RECEPTOR AND CHIMERIC ANTIGEN RECEPTOR FOR STABLE GENETIC MODIFICATION OF CELLULAR IMMUNOTHERAPIESDecember 2019May 2021Allow1740YesNo
16613025GENERATING MAMMALIAN T CELL ACTIVATION INDUCIBLE SYNTHETIC PROMOTERS (SYN+PRO) TO IMPROVE T CELL THERAPYNovember 2019August 2023Allow4511YesNo
16656322ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODYOctober 2019May 2023Abandon4301NoNo
16593832ELECTROPHYSIOLOGICALLY MATURE CARDIOMYOCYTES AND METHODS FOR MAKING SAMEOctober 2019April 2023Abandon4301NoNo
16588357Compositions and Methods for Treating Cancer with Anti-CD33 ImmunotherapySeptember 2019May 2022Allow3100YesNo
16588591Compositions and Methods for Treating Cancer with Anti-ROR1 ImmunotherapySeptember 2019May 2022Allow3220YesNo
16579235HUMAN PLURIPOTENT ADULT STEM CELLSSeptember 2019August 2023Allow4621YesNo
16563422Anti-Tumor Properties of Dickkopf 3bSeptember 2019April 2022Allow3120YesNo
16551337CELL CHARACTERISATIONAugust 2019March 2023Abandon4321NoNo
16546202HIGH SPEED MOLECULAR SENSING WITH NANOPORESAugust 2019October 2022Abandon3701NoNo
16540673MULTIPARTITE SIGNALING PROTEINS AND USES THEREOFAugust 2019April 2022Abandon3211NoNo
16484948COMPOSITION AND METHOD FOR MODULATING FIBROBLAST GROWTH FACTOR RECEPTOR 3 ACTIVATIONAugust 2019December 2022Allow4011YesNo
16534344Fully-human T-cell receptor specific for the 369-377 epitope derived from the Her2/Neu (ERBB2) receptor protein.August 2019February 2022Allow3011YesNo
16530981MULTI-FUNCTION AND MULTI-TARGETING CAR SYSTEM AND METHODS FOR USE THEREOFAugust 2019October 2023Abandon5012YesNo
16529159ELIMINATION OF PD-L1-POSITIVE MALIGNANCIES BY PD-L1 CHIMERIC ANTIGEN RECEPTOR-EXPRESSING NK CELLSAugust 2019May 2021Allow2241YesNo
16529251ELIMINATION OF CD19-POSITIVE LYMPHOID MALIGNANCIES BY CD19-CAR EXPRESSING NK CELLSAugust 2019June 2020Allow1111YesNo
16529029QUADRICISTRONIC SYSTEM COMPRISING A HOMING RECEPTOR AND CHIMERIC ANTIGEN RECEPTOR FOR STABLE GENETIC MODIFICATION OF CELLULAR IMMUNOTHERAPIESAugust 2019January 2021Allow1740YesNo
16526353Engineered Artificial Antigen Presenting Cells for Tumor Infiltrating Lymphocyte ExpansionJuly 2019January 2023Allow4221YesNo
16455077METHODS AND COMPOSITIONS FOR DECREASING CHRONIC PAINJune 2019May 2023Allow4721YesNo
16474426CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAMEJune 2019July 2022Abandon3701NoNo
16446522Coordinating Gene Expression Using RNA Destabilizing ElementsJune 2019May 2020Allow1110YesNo
16446505Coordinating Gene Expression Using RNA Destabilizing ElementsJune 2019April 2020Allow1010YesNo
16443405METHODS FOR SYSTEMICALLY DELIVERING POLYPEPTIDES AND MICROORGANISMS THEREFORJune 2019March 2022Abandon3321YesNo
16442274T CELL-ANTIGEN COUPLER WITH VARIOUS CONSTRUCT OPTIMIZATIONSJune 2019March 2020Allow910YesNo
16469553CHIMERIC ANTIGEN RECEPTOR GENE-MODIFIED LYMPHOCYTE HAVING CYTOCIDAL EFFECTJune 2019July 2023Abandon4921YesNo
16466327STABLY ENGINEREED PROTEASOME INHIBITOR RESISTANT IMMUNE CELLS FOR IMMUNOTHERAPYJune 2019May 2022Abandon3601NoNo
16462492COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINSMay 2019August 2023Allow5131YesNo
16395896RECOMBINANT NUCLEIC ACIDS ENCODING COSMETIC PROTEIN(S) FOR AESTHETIC APPLICATIONSApril 2019May 2020Allow1221YesNo
16343951AP4 AND METHODS OF PROMOTING T CELL ACTIVATIONApril 2019March 2023Allow4731NoNo
16389821HUMANIZED MOUSE MODELApril 2019December 2022Allow4421YesNo
16379610COMPOSITIONS AND METHODS RELATING TO MYOMAKER-INDUCED MUSCLE CELL FUSIONApril 2019May 2022Allow3711YesNo
16340085IMMUNOTHERAPY METHODS AND COMPOSITIONS INVOLVING TRYPTOPHAN METABOLIC PATHWAY MODULATORSApril 2019September 2023Allow5441YesNo
16371501CHIMERIC ANTIGEN RECEPTORS (CARs) TARGETING HEMATOLOGIC MALIGNANCIES, COMPOSITIONS AND METHODS OF USE THEREOFApril 2019June 2023Abandon5131YesNo
16354098GENE-REGULATING COMPOSITIONS AND METHODS FOR IMPROVED IMMUNOTHERAPYMarch 2019January 2023Abandon4621NoNo
16330307IMMUNE CELLS DERIVED FROM INDUCED PLURIPOTENT STEM CELLMarch 2019July 2022Allow4121YesNo
16272679Coordinating Gene Expression Using RNA Destabilizing ElementsFebruary 2019May 2021Allow2741YesNo
16322584PRODUCTION OF MEGAKARYOCTYE COMPOSITIONS AND THERAPIES FOR TREATMENT OF THROMBOCYTOPENIAFebruary 2019November 2021Abandon3421YesNo
16256436LIVE BACTERIAL VACCINES RESISTANT TO CARBON DIOXIDE (CO2), ACIDIC PH AND/OR OSMOLARITY FOR VIRAL INFECTION PROPHYLAXIS OR TREATMENTJanuary 2019September 2022Abandon4421YesNo
16255348CHIMERIC ANTIGEN RECEPTORS TARGETING EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT IIIJanuary 2019October 2021Allow3311YesNo
16245828MRNA THERAPY FOR PHENYLKETONURIAJanuary 2019February 2022Allow3721YesNo
16312794PLURIPOTENT STEM CELL AND T CELL DIFFERENTIATED THEREFROM AND APPLICATION THEREOFDecember 2018February 2022Allow3811YesNo
16312769CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOFDecember 2018September 2022Abandon4511NoNo
16195586INTRACELLULAR OSTEOPONTIN REGULATES THE LINEAGE COMMITMENT OF LYMPHOID SUBSETSNovember 2018February 2022Allow3911YesNo
16192178ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATIONNovember 2018October 2021Abandon3511NoNo
16182808NOVEL BT TOXIN RECEPTORS AND METHODS OF USENovember 2018October 2021Abandon3511NoNo
16179364Compositions and Methods for Treating Cancer with Anti-ROR1 ImmunotherapyNovember 2018May 2019Allow710YesNo
16094247ANTI-ROBO1 CAR-T CELL, AND PREPARATION AND APPLICATION THEREOFOctober 2018March 2022Allow4121YesNo
16159517COMPOUND CHIMERIC ANTIGEN RECEPTOR (cCAR) TARGETING MULTIPLE ANTIGENS, COMPOSITIONS AND METHODS OF USE THEREOFOctober 2018June 2022Abandon4421NoNo
16092837METHODS FOR CREATING SYNTHETIC CHROMOSOMES EXPRESSING BIOSYNTHETIC PATHWAYS AND USES THEREOFOctober 2018February 2023Allow5221YesNo
16148783RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEXOctober 2018September 2020Allow2430YesNo
16135222RECOMBINANT ADENO-ASSOCIATED VIRUS DELIVERY OF ALPHA-SARCOGLYCAN POLYNUCLEOTIDESSeptember 2018January 2022Allow4020YesNo
16128558Modified BacteriophageSeptember 2018September 2022Allow4821YesNo
16083661Methods of Preserving Mesenchymal Stem CellsSeptember 2018January 2023Allow5231YesNo
16083503Mesoderm Induction Method Having High Blood Cell Differentiation CapacitySeptember 2018July 2021Allow3411YesNo
16082929CULTURE MEDIUM COMPOSITION FOR SUSPENSION CULTURE ALLOWING EASY CELL RECOVERY, AND CELL RECOVERY METHODSeptember 2018October 2021Allow3821YesNo
16082691TUMOR CELL SUSPENSION CULTURES AND RELATED METHODSSeptember 2018March 2023Allow5431YesNo
16120055NIPAH VIRUS ENVELOPE PSEUDOTYPED LENTIVIRUSES AND METHODS OF THEIR USEAugust 2018September 2022Allow4931YesNo
15998685Integrated methods for precision manufacturing of tissue engineering scaffoldsAugust 2018March 2021Allow3111YesNo
16074539Methods for Generation of Cell-derived Microfilament NetworkAugust 2018August 2021Allow3731YesNo
16048676MicroRNAS FOR THE GENERATION OF ASTROCYTESJuly 2018February 2021Abandon3001NoNo
16049041DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS TO MULTIPOTENT NEURAL CREST CELLSJuly 2018February 2022Abandon4221NoNo
16046083Compositions and Methods of Delivering Treatments for Latent Viral InfectionsJuly 2018March 2021Abandon3210NoNo
16073297COMPOSITION FOR INDUCING BEIGE ADIPOCYTE DIFFERENTIATION CONTAINING EXOSOME DERIVED FROM STEM CELLSJuly 2018March 2021Allow3111YesNo
16037942METHODS AND COMPOSITIONS FOR MODIFICATION OF A HLA LOCUSJuly 2018August 2020Allow2500YesNo
16036638EXPANSION OF RENEWABLE STEM CELL POPULATIONSJuly 2018January 2021Abandon3001NoNo
16026199METHODS AND COMPOSITIONS FOR DETACHING ADHERENT CELLSJuly 2018August 2021Abandon3820YesNo
16026539CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEINJuly 2018September 2021Abandon3921NoNo
16018435METHOD FOR PRODUCING CONTINUOUS CELL LINESJune 2018January 2021Abandon3110NoNo
16015159GENETICALLY MODIFIED MAJOR HISTOCOMPATIBILITY COMPLEX ANIMALSJune 2018May 2020Allow2331YesNo
16007928MINIMAL VOLUME REPROGRAMMING OF MONONUCLEAR CELLSJune 2018November 2020Allow2910YesNo
16061091GENE THERAPY FOR COMBINED METHYLMALONIC ACIDEMIA/ACIDURIA AND HYPERHOMOCYSTEINEMIA/HOMOCYSTINURIA, COBALAMIN C TYPE, AND DEFICIENCY OF MMACHCJune 2018July 2022Allow4921YesNo
16005645GENE KNOCKOUT METHOD BASED ON BASE EDITING AND ITS APPLICATIONJune 2018December 2021Allow4221YesNo
16060252IMMORTALISED CHICKEN EMBRYONIC EPITHELIAL KIDNEY CELLSJune 2018June 2021Abandon3621NoNo
16002604EXPRESSION OF HIV INHIBITORS BY MESENCHYMAL STEM CELLSJune 2018February 2022Allow4441YesNo
15996271Method For Inducing Antitumor Immunity Using Sindbis Viral Vectors And Tumor Associated AntigensJune 2018March 2021Abandon3411NoNo
15991833GENERATION OF HUMAN MACROPHAGES IN IMMUNODEFICIENT NON-HUMAN HOSTSMay 2018April 2021Abandon3511NoNo
15779578METHOD FOR MANUFACTURING MESENCHYMAL CELL LINE DERIVED FROM VERTEBRATE ANIMAL ADIPOSE TISSUEMay 2018July 2022Allow5031YesNo
15935768CELL TISSUE GEL CONTAINING COLLAGEN AND HYALURONANMarch 2018October 2021Abandon4221NoNo
15934177IN VITRO PRODUCTION OF RED BLOOD CELLS WITH SORTAGGABLE PROTEINSMarch 2018October 2021Allow4321YesNo
15934770Compositions and Methods for Treating Cancer with Anti-CD33 ImmunotherapyMarch 2018May 2019Allow1420YesNo
15927007GENETIC METHOD TO KILL CANCER CELLS BY SUFFOCATIONMarch 2018December 2019Abandon2121NoNo
15927040TREATING CANCER WITH CAS ENDONUCLEASE COMPLEXESMarch 2018May 2021Abandon3821NoNo
15759501IMMUNOGENIC ANTIGEN IDENTIFICATION FROM A PATHOGEN AND CORRELATION TO CLINICAL EFFICACYMarch 2018May 2021Allow3921YesNo
15916446COMPOSITIONS AND METHODS FOR BACTERIAL DELIVERY OF POLYPEPTIDESMarch 2018December 2020Abandon3410NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner LEAVITT, MARIA GOMEZ.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
8
Examiner Affirmed
3
(37.5%)
Examiner Reversed
5
(62.5%)
Reversal Percentile
84.5%
Higher than average

What This Means

With a 62.5% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
70
Allowed After Appeal Filing
12
(17.1%)
Not Allowed After Appeal Filing
58
(82.9%)
Filing Benefit Percentile
21.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 17.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner LEAVITT, MARIA GOMEZ - Prosecution Strategy Guide

Executive Summary

Examiner LEAVITT, MARIA GOMEZ works in Art Unit 1633 and has examined 736 patent applications in our dataset. With an allowance rate of 44.2%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 35 months.

Allowance Patterns

Examiner LEAVITT, MARIA GOMEZ's allowance rate of 44.2% places them in the 10% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by LEAVITT, MARIA GOMEZ receive 2.21 office actions before reaching final disposition. This places the examiner in the 57% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by LEAVITT, MARIA GOMEZ is 35 months. This places the examiner in the 38% percentile for prosecution speed. Prosecution timelines are slightly slower than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +66.7% benefit to allowance rate for applications examined by LEAVITT, MARIA GOMEZ. This interview benefit is in the 98% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 21.4% of applications are subsequently allowed. This success rate is in the 28% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 33.6% of cases where such amendments are filed. This entry rate is in the 52% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 18.2% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 27% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 78.4% of appeals filed. This is in the 70% percentile among all examiners. Of these withdrawals, 75.9% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 75.3% are granted (fully or in part). This grant rate is in the 80% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 1.2% of allowed cases (in the 69% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.