USPTO Examiner STAVROU CONSTANTINA E - Art Unit 1632

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19227561BRAIN ORGANOID CONTAINING OPTIC VESICLES GENERATED BASED ON H9 INDUCTION AND EYE-BRAIN FUSION CULTURE METHODJune 2025February 2026Allow811YesNo
18650881ENGINEERED IMMUNE CELLS WITH RECEPTOR SIGNAL STRENGTH MODULATED BY A HINGEApril 2024July 2025Allow1410NoNo
18503557GENE THERAPY COMPOSITION AND TREATMENT OF RIGHT VENTRICULAR ARRHYTHMOGENIC CARDIOMYOPATHYNovember 2023July 2025Abandon2021NoNo
18328473SWITCH RECEPTORS USING IL-9 SIGNALING DOMAINSJune 2023September 2024Allow1621NoNo
17957998OPTICALLY CONTROLLABLE FGFR STIMULATION USING WIRELESS CONTROLLED CELLULAR LIGHTING SYSTEMSeptember 2022November 2025Abandon3840YesNo
17946894SWITCH RECEPTORS USING IL-9 SIGNALING DOMAINSSeptember 2022February 2024Abandon2601NoNo
17878628ANIMAL MODELS AND THERAPEUTIC MOLECULESAugust 2022December 2025Abandon4010NoNo
17874433METHOD FOR EFFICIENTLY INDUCING REPROGRAMMING OF HUMAN CELL INTO NEURONAL CELLJuly 2022June 2024Abandon2321NoNo
17663372MICROENCAPSULATION-BASED ISOLATION OF HUMAN PLURIPOTENT AND MULTIPOTENT STEM CELLS AND METHODS OF MAKING AND USING THE SAMEMay 2022March 2024Abandon2211NoNo
17728956Differentiation of Olfactory Mucosa Derived Mesenchymal Stem Cells to Schwann Cells for Peripheral Nerve RepairApril 2022October 2024Allow3031NoNo
17723159ENGINEERED CATFISH AND USES THEREOFApril 2022August 2025Allow4031YesNo
17681647RETROVIRAL VECTORSFebruary 2022July 2024Allow2931YesNo
17582730CHEMICALLY DEFINED MEDIUM FOR DIFFERENTIATION OF MUSCLE STEM CELLS IN VITROJanuary 2022September 2025Abandon4341YesNo
17578955ENGINEERED ANTIGEN PRESENTING CELLSJanuary 2022July 2025Abandon4231NoNo
17552464Animal Model for SARS-CoV-2-Spike Induced CoagulopathyDecember 2021February 2024Allow2611YesNo
17545034MESENCHYMAL STEM CELL CULTURE PRODUCT AND METHOD FOR PREPARING THE SAMEDecember 2021February 2025Abandon3831YesNo
17512496PROTECTION AND REGENERATION OF NEUROLOGICAL FUNCTION BY USING STEM CELLSOctober 2021August 2024Abandon3320NoNo
17497364VASCULARIZED ORGANOID MODEL INCORPORATING ISOLATED HUMAN MICROVESSEL FRAGMENTSOctober 2021March 2024Abandon2911NoNo
17600432Improved Manufacturing Procedures for Cell Based TherapiesSeptember 2021February 2026Abandon5330NoNo
17487926ASCL1 VECTORSeptember 2021November 2024Abandon3721NoNo
17480490ENGINEERED IMMUNE CELLS WITH RECEPTOR SIGNAL STRENGTH MODULATED BY A HINGESeptember 2021January 2024Allow2820NoNo
17458909ENGINEERED ONCOLYTIC VIRUSES EXPRESSING PD-L1 INHIBITORS AND USES THEREOFAugust 2021November 2023Abandon2611NoNo
17397073LUNG BREATHING CHIP AND CELL STRETCHING CULTURE PLATFORM AND OPERATING METHOD THEREOFAugust 2021September 2025Abandon5051NoNo
17426389RECOMBINANT NUCLEIC ACIDS CONTAINING ALPHAHERPESVIRUS PROMOTER SEQUENCESJuly 2021October 2025Allow5021NoNo
17443415KITS AND METHOD OF MODIFYING, DETECTING, AND SORTING ANTIBODY-PRODUCING CELLSJuly 2021September 2024Abandon3721NoNo
17347360TRANSIENT REPORTERS AND METHODS FOR BASE EDITING ENRICHMENTJune 2021April 2025Allow4641NoNo
17324169CELL-CONTAINING VESSEL AND METHOD FOR PRODUCING NEURAL CELL-CONTAINING SPHEROIDMay 2021November 2024Abandon4241YesNo
17237498COMPOSITIONS AND METHODS OF TREATING CANCER WITH CHIMERIC ANTIGEN RECEPTORSApril 2021October 2023Allow3011YesNo
17283942METHOD FOR FABRICATION OF THREE-DIMENSIONAL LUNG ORGANOID COMPRISING HUMAN STEM CELL-DERIVED ALVEOLAR MACROPHAGEApril 2021September 2024Allow4121NoNo
17213299METHOD OF USING A TLR9 ANTAGONIST AS AN ANTI-INFLAMMATORY AND ANTI-FIBROTIC AGENTMarch 2021February 2025Abandon4621NoNo
17277637METHODS OF PRODUCING VENOUS ANGIOBLASTS AND SINUSOIDAL ENDOTHELIAL CELL-LIKE CELLS AND COMPOSITIONS THEREOFMarch 2021January 2026Abandon5821NoNo
17277241PHARMACEUTICAL PRODUCT FOR PREVENTING OR TREATING ALZHEIMER'S DISEASEMarch 2021August 2025Abandon5320NoNo
17194972PRODUCTION OF EXTRACELLULAR VESICLES FROM STEM CELLSMarch 2021August 2025Allow5341YesNo
17182422ANTI-CD33 AND NKG2D LIGAND CHIMERAS FOR TREATMENT OF MYELOID MALIGNANCIESFebruary 2021August 2024Abandon4101NoNo
17172818MODIFICATION OF HEAVY CHAIN FIBROIN IN BOMBYX MORIFebruary 2021February 2024Abandon3611NoNo
17152220OPTICALLY CONTROLLABLE FGFR STIMULATION USING WIRELESS CONTROLLED CELLULAR LIGHTING SYSTEMJanuary 2021August 2024Allow4211YesNo
17129527PRESERVATION OF PHAGE CONCENTRATION IN CLINICAL SAMPLESDecember 2020December 2024Abandon4821NoNo
17254263GENERATION OF A POPULATION OF HINDBRAIN CELLS AND HINDBRAIN-LIKE ORGANOIDS FROM PLURIPOTENT STEM CELLSDecember 2020October 2025Allow5821NoNo
17247661EXTRACELLULAR VESICLES DERIVED FROM OSTEOBLAST LINEAGE CELLS FOR THERAPEUTIC AND DIAGNOSTIC USEDecember 2020February 2025Abandon5031YesNo
17118555COMPOSITION AND METHOD FOR INDUCTION OF PLURIPOTENT STEM CELLDecember 2020December 2024Abandon4821NoNo
17116332GENOME-EDITED INDUCED PLURIPOTENT STEM CELLS, AND CELLS DERIVED THEREFROM, AND USES THEREOFDecember 2020August 2024Allow4411NoNo
16973108ENGINEERED HEMATOPOIETIC STEM CELLS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIADecember 2020November 2024Abandon4811NoNo
17104528PLATELETS LOADED WITH mRNANovember 2020June 2023Abandon3010NoNo
17058245METHOD FOR THE VITRIFICATION OF HUMAN SEMEN AND PORTABLE KIT FOR THE APPLICATION OF SAID METHODNovember 2020October 2025Allow5941NoNo
17058163COMBINATION THERAPY WITH CHIMERIC ANTIGEN RECEPTOR (CAR) THERAPIESNovember 2020August 2024Abandon4501NoNo
17055673GENE THERAPY VECTORS COMPRISING S/MAR SEQUENCESNovember 2020October 2025Abandon5931NoNo
17053668CELL SCAFFOLD MATERIALNovember 2020August 2024Abandon4501NoNo
17050312METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLSOctober 2020September 2025Abandon5931YesNo
17049974NUCLEIC ACID MOLECULES AND DUAL-FUNCTIONAL PEPTIDES HAVING ANTIVIRAL ACTIVITY AND DELIVERY ACTIVITY, COMPOSITIONS AND METHODS THEREOFOctober 2020February 2026Allow6031YesNo
17043836Composition For Inducing Dedifferentiation From Somatic Cells To Induced Pluripotent Stem Cells And Method of Inducing Dedifferentiation Using SameSeptember 2020March 2024Allow4211NoNo
17036476COMPOSITION THAT CONTAINS POLYLYSINE ANALOG AND PROMOTES CELL GROWTHSeptember 2020February 2024Abandon4001NoNo
17040623METHODS OF CYTOPLASMIC INCOMPATIBILITY-BASED TRANSGENICS FOR PEST OR VECTOR CONTROLSeptember 2020March 2026Abandon6041NoNo
16981421CRYOPRESERVING PROCESSESSeptember 2020January 2024Allow4010NoNo
16981077REAGENTS AND METHODS WITH WNT AGONISTS AND BIOACTIVE LIPIDS FOR GENERATING AND EXPANDING CARDIOMYOCYTESSeptember 2020June 2025Allow5731YesNo
16979956STEPWISE METHOD OF PRODUCING VARIOUS TYPES OF CELLS FROM PLURIPOTENT STEM CELLSSeptember 2020August 2025Allow5931YesNo
16979215DENTAL ADHESIVE HYDROGELS AND USES THEREOFSeptember 2020September 2025Abandon6031NoNo
16978573HUMAN PAPILLOMAVIRUS VACCINES AND USES OF THE SAMESeptember 2020April 2025Allow5521NoNo
16977106COMPOSITIONS FOR USE IN THE TREATMENT OF MUSCULOSKELETAL CONDITIONS AND METHODS FOR PRODUCING THE SAME LEVERAGING THE SYNERGISTIC ACTIVITY OF TWO DIFFERENT TYPES OF MESENCHYMAL STROMAL/STEM CELLSSeptember 2020November 2024Abandon5031YesNo
16976581Compositions and Methods for Efficient Amplification of Retinal Progenitors CellsAugust 2020August 2025Allow5941YesNo
16971634MORPHOGENIC COMPOUND-RELEASING MICROSPHERES AND USE IN BIOINKAugust 2020May 2025Abandon5731YesNo
16994336METHODS FOR NUCLEAR REPROGRAMMING OF CELLSAugust 2020March 2024Allow4321YesNo
16958013ARTIFICIAL TISSUE PERFUSION DEVICE AND METHOD OF DRUG ASSESSMENT USING ARTIFICIAL TISSUEJuly 2020April 2024Abandon4601NoNo
16962880METHOD FOR PRODUCING EXOSOMES AND EXOSOMES OBTAINED THEREBYJuly 2020June 2023Allow3520YesNo
16957010MESENCHYMAL STROMAL CELLS AND METHODS FOR OBTAINING MESENCHYMAL STROMAL CELLS FROM UMBILICAL CORDJune 2020November 2024Abandon5321NoNo
16956500METHOD FOR ISOLATING HUMAN DERMAL FIBROBLASTSJune 2020March 2024Abandon4521NoNo
16652803APPLICATION OF PLURIPOTENT STEM CELLS HAVING MODIFIED DIFFERENTIAL POTENTIAL TO PRODUCING ANIMALSJune 2020September 2023Abandon4211YesNo
16756067CARTILAGE TISSUE PRODUCING METHOD AND CARTILAGE TISSUEApril 2020January 2024Abandon4520NoNo
16820316METHOD FOR THE TREATMENT OF CANCERS BY MEANS OF GENETIC NEUROENGINEERINGMarch 2020October 2023Abandon4311NoNo
16644808NOVEL CELL LINE AND USES THEREOFMarch 2020July 2023Allow4111YesNo
16641137BIOENGINEERED IN VITRO 3D MODEL OF HUMAN ATHEROSCLEROTIC PLAQUEFebruary 2020November 2023Allow4521YesNo
16638693COMPOSITIONS AND METHODS FOR ENHANCING MATURATION STATES OF HEALTHY AND DISEASED CARDIOMYOCYTESFebruary 2020May 2024Abandon5121NoNo
16638483METHODS OF MATURATION OF HUMAN SPERMATOGONIUMFebruary 2020July 2024Abandon5341NoNo
16776503COMPOSITIONS AND METHODS FOR REGULATING PROTEINS AND NUCLEIC ACIDS ACTIVITIESJanuary 2020December 2023Allow4621YesNo
16629402THE METHOD OF AUTOLOGOUS PRIMARY HAIR FOLLICLES PREPARATION IN 3D CULTUREJanuary 2020October 2024Allow5850NoNo
16607836GENERATING HUMAN CELLS CAPABLE OF PRODUCING INSULIN IN RESPONSE TO GLUCOSE OR GLP-1October 2019July 2024Abandon5711NoNo
16331410COMPOSITIONS AND METHODS FOR EVALUATING AND MODULATING IMMUNE RESPONSESMarch 2019October 2025Abandon6042YesNo
15536725TRANSGENIC RPE CELLS OVEREXPRESSING OTX2 FOR THE TREATMENT OF RETINAL DEGENERATIONJune 2017August 2023Allow6071YesNo

Appeals Overview

No appeal data available for this record. This may indicate that no appeals have been filed or decided for applications in this dataset.

Examiner STAVROU, CONSTANTINA E - Prosecution Strategy Guide

Executive Summary

Examiner STAVROU, CONSTANTINA E works in Art Unit 1632 and has examined 63 patent applications in our dataset. With an allowance rate of 39.7%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 46 months.

Allowance Patterns

Examiner STAVROU, CONSTANTINA E's allowance rate of 39.7% places them in the 7% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by STAVROU, CONSTANTINA E receive 2.21 office actions before reaching final disposition. This places the examiner in the 61% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by STAVROU, CONSTANTINA E is 46 months. This places the examiner in the 10% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +36.8% benefit to allowance rate for applications examined by STAVROU, CONSTANTINA E. This interview benefit is in the 85% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 19.4% of applications are subsequently allowed. This success rate is in the 20% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 31.8% of cases where such amendments are filed. This entry rate is in the 46% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Petition Practice

When applicants file petitions regarding this examiner's actions, 85.7% are granted (fully or in part). This grant rate is in the 86% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 1% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 1% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.