USPTO Examiner MOLOYE TITILAYO - Art Unit 1632

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17135916RXR-ALPHA�GENE�KNOCKOUT�CELL�LINE�WITH�STABLE�AND�LOW�RXR-ALPHA PROTEIN�EXPRESSION�AND�PRODUCTION�METHOD�THEREOFDecember 2020November 2024Abandon4701NoNo
17133326CORNEAL ENDOTHELIAL CELL MARKERDecember 2020April 2024Allow4021YesNo
17131514APPARATUSES AND METHODS FOR PREPARING A COMESTIBLE MEAT PRODUCTDecember 2020March 2022Allow1530YesNo
17129708ADAM6 MICEDecember 2020December 2023Allow3511YesNo
17129706ADAM6 MICEDecember 2020September 2024Allow4511YesNo
17114888REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREOFDecember 2020January 2024Allow3720NoNo
17110446THREE DIMENSIONAL TISSUE PRINTING DEVICE, THREE DIMENSIONAL TISSUE PRINTING METHOD AND ARTIFICIAL SKINDecember 2020August 2024Abandon4521NoNo
17105156DIRECTED STEM CELL RECRUITMENTNovember 2020June 2023Allow3120NoNo
17056710SYSTEM OF CELL EXPANSION AND METHODS OF USING THE SAMENovember 2020January 2025Abandon5011NoNo
17094350APPARATUS AND METHOD FOR LEVITATIONAL BIOFABRICATION OF ORGAN AND TISSUE ENGINEERED CONSTRUCTS USING TISSUE SPHEROIDS AND MAGNETOACOUSTIC BIFIELDNovember 2020March 2024Abandon4010NoNo
17094327MESSENGER RNA THERAPY FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLASE DEFICIENCYNovember 2020September 2024Allow4621YesNo
17081766RECOMBINANT ADENO-ASSOCIATED VIRUS-MEDIATED EXPRESSION OF FRACTALKINE FOR TREATMENT OF NEUROINFLAMMATORY AND NEURODEGENERATIVE DISEASESOctober 2020July 2023Abandon3310NoNo
17074481METHODS AND COMPOSITIONS FOR FEEDER-FREE PLURIPOTENT STEM CELL MEDIA CONTAINING HUMAN SERUMOctober 2020June 2023Allow3210NoNo
17071511TARGETING THE TUMOR MICROENVIRONMENT USING MANIPULATED NKT CELLSOctober 2020September 2023Abandon3510NoNo
17071507TARGETING THE TUMOR MICROENVIRONMENT USING MANIPULATED NKT CELLSOctober 2020July 2023Abandon3310NoNo
17071627USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCYOctober 2020June 2024Allow4420NoNo
17046264CELL STRUCTURE CONNECTION METHOD AND CONNECTION SUPPORT DEVICEOctober 2020April 2025Allow5421YesNo
17063139METHOD FOR DIFFERENTIATION INDUCTION IN CULTURED STEM CELLSOctober 2020May 2024Allow4320YesNo
17039784ARTIFICIAL RECOMBINANT CHROMOSOME AND USE THEREOFSeptember 2020June 2025Abandon5780YesNo
17039407BIOLOGICALLY ACTIVE C-TERMINAL ARGININE-CONTAINING PEPTIDESSeptember 2020June 2024Abandon4410NoNo
17039839RNA-Guided Endonuclease Expressing Algal Strain for High Efficiency In Vivo Genome EditingSeptember 2020March 2024Allow4220NoNo
17042635CARDIOMYOCYTE MATURATION PROMOTERSeptember 2020February 2024Allow4110NoNo
17014113PSORIASIS-INDUCED ANIMAL MODEL AND USE THEREOFSeptember 2020December 2023Abandon3920NoNo
17010054GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENESSeptember 2020June 2021Allow1011YesNo
17001319MICROVESICLE AND METHOD FOR PRODUCING THE SAMEAugust 2020May 2023Abandon3310NoNo
16991758METHOD FOR RECONSTRUCTING IMMUNE FUNCTION USING PLURIPOTENT STEM CELLSAugust 2020December 2023Allow4020YesNo
16934503SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAMEJuly 2020April 2021Allow910NoNo
16913741METHOD TO BIOENGINEER DESIGNER RED BLOOD CELLS USING GENE EDITING AND STEM CELL METHODOLOGIESJune 2020December 2024Abandon5431NoNo
16958218SCAFFOLDING MATERIAL FOR STEM CELL CULTURES AND STEM CELL CULTURE METHOD USING SAMEJune 2020April 2025Allow5760YesNo
16908037Skeletal muscle augmentation utilizing muscle-derived progenitor compositions, and treatments thereofJune 2020July 2023Abandon3720NoNo
16860519Functional Targeted Brain EndoskeletonizationApril 2020October 2022Abandon3010NoNo
16846476SYSTEMS AND METHODS FOR ANGIOGENIC TREATMENT IN WOUND HEALINGApril 2020May 2024Allow4930NoNo
16840302HUMAN IPSC-BASED DRUG TESTING PLATFORM FOR MUSCULAR DYSTROPHYApril 2020July 2024Allow5221YesYes
16836644COMPOSITIONS AND METHODS FOR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHYMarch 2020February 2021Allow1011YesNo
16834727Biosensors in Human Gut OrganoidsMarch 2020November 2023Allow4321YesNo
16831244ENHANCEMENT OF PRODUCTION OF NK CELLS FROM STEM CELLSMarch 2020September 2022Allow2941YesNo
16649475IN VITRO METHOD FOR PROVIDING STEM CELL DERIVED CARDIOMYOCYTESMarch 2020May 2023Abandon3801NoNo
16648186FABRICATION OF A BIOMIMETIC PLATFORM SYSTEM AND METHODS OF USEMarch 2020January 2025Abandon5830NoNo
16820657METHODS AND COMPOSITIONS FOR PREPARING CARDIOMYOCYTES FROM STEM CELLS AND USE THEREOFMarch 2020June 2024Abandon5140NoNo
16809771NOVEL METHODS AND CULTURE MEDIA FOR CULTURING PLURIPOTENT STEM CELLSMarch 2020January 2024Allow4610NoNo
16639090A RELIABLE AND REPRODUCIBLE INDUSTRIALISATION PROCESS FOR THE ELIMINATION OF AIR BUBBLES IN THE PRODUCTION OF AN ENGINEERED VASCULAR TISSUEFebruary 2020February 2024Abandon4821NoNo
16751699AAV-VECTORS FOR USE IN GENE THERAPY OF CHOROIDEREMIAJanuary 2020October 2022Abandon3301NoNo
16736802COMPOSITIONS AND METHODS FOR DETECTING CARDIOTOXICITYJanuary 2020March 2025Abandon6040NoNo
16727449RIBOFLAVIN DERIVATIVE-CONTAINING MEDIUMDecember 2019January 2025Allow6050YesNo
16719848METHOD OF MAKING A PERSONALIZED BONE GRAFTDecember 2019May 2022Allow2910NoNo
16624176MICROTISSUE COMPARTMENT DEVICEDecember 2019September 2022Allow3331YesNo
16713808GUT ORGANOID AND METHOD FOR PRODUCING THE SAMEDecember 2019December 2024Allow6041YesNo
16712645Engineered Three-Dimensional Breast Tissue, Adipose Tissue, and Tumor Disease ModelDecember 2019May 2023Allow4121YesNo
16708152BACTERIA CARRYING BACTERIOPHAGE AND PROTEASE INHIBITORS FOR THE TREATMENT OF DISORDERS AND METHODS OF TREATMENTDecember 2019June 2023Allow4221YesNo
16656452COMBINATORIAL CANCER IMMUNOTHERAPYOctober 2019December 2020Allow1411YesNo
16604973COMBINATORIAL CANCER IMMUNOTHERAPYOctober 2019April 2022Allow3031NoNo
16599732METHODS, DEVICES, AND COMPOSITIONS FOR MEASURING AND INDUCING CELL-TO-CELL COMMUNICATION, AND THERAPEUTIC USES THEREOFOctober 2019October 2023Allow4811YesNo
16595089BIOPROSTHETIC TISSUE HAVING A REDUCED PROPENSITY FOR IN VIVO CALCIFICATIONOctober 2019December 2021Allow2610NoNo
16588864METHODS OF DIFFERENTIATING PREADIPOCYTES AND USES THEREOFSeptember 2019March 2023Allow4121YesNo
16581150COMPOSITIONS AND METHODS FOR THE TREATMENT OF NETHERTON SYNDROMESeptember 2019December 2022Abandon3860YesYes
16576803PRODUCTION OF CELLULAR SPHEROIDSSeptember 2019July 2024Allow5821YesNo
16494249METHOD OF GENERATING 2 CELL-LIKE STEM CELLSSeptember 2019July 2023Abandon4621NoNo
16562176CELL LINE, SYSTEM AND METHOD FOR OPTICAL-BASED SCREENING OF ION-CHANNEL MODULATORSSeptember 2019October 2021Abandon2601NoNo
16490302METHODS AND SYSTEMS FOR FUNCTIONAL MATURATION OF iPSC AND ESC DERIVED CARDIOMYOCYTESAugust 2019April 2023Allow4421YesNo
16486212CELL CULTURE METHOD AND CELL CULTURE SYSTEMAugust 2019February 2025Allow6070YesNo
16533830MAMMALIAN GENE MODIFICATION METHOD USING ELECTROPORATIONAugust 2019March 2021Abandon1901NoNo
16515155Engineered Liver Tissues, Arrays Thereof, and Methods of Making the SameJuly 2019May 2021Allow2220NoNo
16511612Use of Ion Concentrations to Increase the Packaging Efficiency of Recombinant Adeno-Associated VirusJuly 2019August 2020Allow1320YesNo
16510731THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONSJuly 2019October 2021Allow2720NoNo
16476564CRYOGEL 3D SCAFFOLDS AND METHODS FOR PRODUCING THEREOFJuly 2019March 2023Allow4410YesNo
16471312Composition for Promoting Proliferation of Pluripotent Stem Cells, and Method for Promoting Proliferation of Pluripotent Stem CellsJune 2019June 2023Allow4840YesNo
16470584METHOD FOR EFFICIENTLY PRODUCING 3D MIDBRAIN-LIKE ORGANOID THROUGH SPECIFIC ELECTROMAGNETIC WAVE PROCESSINGJune 2019February 2024Allow5650NoNo
16435724ANTICANCER COMPOSITION COMPRISING RECOMBINANT ADENOVIRUS EXPRESSING DEGRADATION FACTOR FOR EXTRACELLULAR MATRIXJune 2019April 2025Abandon6081YesNo
16466177USE OF PEPTIDE COMPOUNDS FOR PROMOTING SURVIVAL, GROWTH AND CELL DIFFERENTIATIONJune 2019July 2024Allow6041YesNo
16462753PERSONALIZED CELLULAR BIOMANUFACTURING WITH A CLOSED, MINIATURE CELL CULTURE SYSTEMMay 2019November 2022Abandon4211NoNo
16404430System for Optical Stimulation of Target CellsMay 2019September 2020Abandon1611NoNo
16345180GENETICALLY MODIFIED MOUSE MODEL FOR HUMAN HEPATOCYTE XENOTRANSPLANTATIONApril 2019November 2023Abandon5421NoNo
16341525COMPOSITIONS, CELL CONSTRUCTS, AND METHODS OF MAKING AND USING THE SAMEApril 2019September 2023Allow5341YesNo
16372358METHODS AND COMPOSITIONS FOR FEEDER-FREE PLURIPOTENT STEM CELL MEDIA CONTAINING HUMAN SERUMApril 2019February 2020Abandon1010NoNo
16356570ORGAN REGENERATION METHOD UTILIZING BLASTOCYST COMPLEMENTATIONMarch 2019October 2021Abandon3111NoNo
16356005SCALABLE LENTIVIRAL VECTOR PRODUCTION SYSTEM COMPATIBLE WITH INDUSTRIAL PHARMACEUTICAL APPLICATIONSMarch 2019September 2021Abandon3021NoYes
16331661METHOD AND APPARATUS FOR A TISSUE ENGINEERING SYSTEMMarch 2019February 2021Allow2401NoNo
16297070Preparation of artificial tissues by means of tissue engineering using fibrin and agarose biomaterialsMarch 2019August 2023Abandon5430YesNo
16288809COMPOSITIONS CONTAINING AMNIOTIC COMPONENTS AND METHODS FOR PREPARATION AND USE THEREOFFebruary 2019January 2022Allow3531YesNo
16288831Extracellular Matrix-Derived Gels and Related MethodsFebruary 2019March 2022Abandon3710NoNo
16278383ISOLATED PLACENTAL STEM CELL RECRUITING FACTORSFebruary 2019July 2022Allow4120NoNo
16278415TARGETING DNA VACCINES TO B CELLS AS PRIMARY ANTIGEN PRESENTING CELLSFebruary 2019March 2021Abandon2520NoNo
16322232BLOOD BRAIN BARRIER MODEL AND METHODS OF MAKING AND USING THE SAMEJanuary 2019September 2021Allow3121YesNo
16262442ONCOLYTIC EXPRESSION VECTOR COMPRISING A NUCLEIC ACID COMPRISING A NUCLEOTIDE SEQUENCE ENCODING GADD34January 2019November 2019Allow1010NoNo
16258908METHOD OF GENE TRANSFER FOR THE TREATMENT OF RECESSIVE CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA (CPVT)January 2019July 2021Allow2910NoNo
16256147NERVE TREATMENT DEVICES AND METHODSJanuary 2019August 2021Abandon3110NoNo
16315687PSORIASIS-INDUCED ANIMAL MODEL AND USE THEREOFJanuary 2019December 2020Abandon2321NoNo
16312772HEPATIC CELL LINE RESISTANT TO DIMETHYL SULFOXIDE, CELL CULTURE AND USES THEREOFDecember 2018September 2022Abandon4501NoNo
16311859ENGINEERED CARDIOMYOCYTES AND USES THREOFDecember 2018May 2022Abandon4101NoNo
16310632BIOLOGICALLY RELEVANT IN VITRO SCREENING OF HUMAN NEURONSDecember 2018July 2022Abandon4310NoNo
16304740NEOEPITOPE VACCINE COMPOSITIONS AND METHODS OF USE THEREOFNovember 2018May 2021Abandon2931YesNo
16197194FUSION PROTEINS COMPRISING PDGF AND VEGF BINDING PORTIONS AND METHODS OF USING THEREOFNovember 2018March 2021Allow2821YesNo
16194945Combinational use of mechanical manipulation and programin derivatives to increase Oct4, Sox2, Nanog or c-Myc expression in fibroblastsNovember 2018April 2020Allow1721YesNo
16177728COMPOSITION AND METHODS FOR CULTURING RETINAL PROGENITOR CELLSNovember 2018June 2022Abandon4410NoNo
16173875TARGETED DISRUPTION OF T CELL RECEPTOR GENES USING ENGINEERED ZINC FINGER PROTEIN NUCLEASESOctober 2018April 2022Allow4120NoNo
16172364Metabolic Pressure for Stem Cell Differentiation and PurificationOctober 2018May 2022Abandon4301NoNo
16096980ISL1-Based Gene Therapy to Treat Hearing LossOctober 2018March 2022Abandon4141YesYes
16157930STEM CELL-DERIVED HEPATOCYTES IN CO-CULTURE AND USES THEREOFOctober 2018April 2020Allow1821YesNo
16092328IN VITRO MODEL FOR BLOOD-BRAIN BARRIER AND METHOD FOR PRODUCING IN VITRO MODEL FOR BLOOD-BRAIN BARRIEROctober 2018June 2022Allow4410NoNo
16091450ISOGENIC BLOOD-BRAIN BARRIER MODELOctober 2018August 2023Allow5831YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner MOLOYE, TITILAYO.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
7
Examiner Affirmed
5
(71.4%)
Examiner Reversed
2
(28.6%)
Reversal Percentile
44.7%
Lower than average

What This Means

With a 28.6% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
58
Allowed After Appeal Filing
14
(24.1%)
Not Allowed After Appeal Filing
44
(75.9%)
Filing Benefit Percentile
33.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 24.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner MOLOYE, TITILAYO - Prosecution Strategy Guide

Executive Summary

Examiner MOLOYE, TITILAYO works in Art Unit 1632 and has examined 486 patent applications in our dataset. With an allowance rate of 60.7%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 40 months.

Allowance Patterns

Examiner MOLOYE, TITILAYO's allowance rate of 60.7% places them in the 22% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by MOLOYE, TITILAYO receive 2.86 office actions before reaching final disposition. This places the examiner in the 80% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by MOLOYE, TITILAYO is 40 months. This places the examiner in the 23% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +53.5% benefit to allowance rate for applications examined by MOLOYE, TITILAYO. This interview benefit is in the 94% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 18.4% of applications are subsequently allowed. This success rate is in the 20% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 39.9% of cases where such amendments are filed. This entry rate is in the 62% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 100.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 71% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 81.6% of appeals filed. This is in the 74% percentile among all examiners. Of these withdrawals, 71.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 86.3% are granted (fully or in part). This grant rate is in the 87% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.4% of allowed cases (in the 57% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 1% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.