USPTO Examiner DHAR MATASHA - Art Unit 1632

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18984398METHOD FOR GENERATING GENOME-EDITED CHICKENSDecember 2024June 2025Allow610YesNo
18948566GENETICALLY MODIFIED RAT HAVING PKHD1L1 GENE WITH POINT MUTATION AND METHODS FOR ITS CONSTRUCTION, DETECTION AND USENovember 2024February 2026Allow1521YesNo
18612882ENGINEERED CLASS 2, TYPE V REPRESSOR SYSTEMSMarch 2024September 2025Allow1831NoNo
18381652VASCULARIZED CARDIAC ORGANOID WITH A CHAMBER STRUCTURE AND ITS PREPARATION METHODOctober 2023September 2024Allow1110YesNo
18484279VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR 21 (FGF21) CODING SEQUENCEOctober 2023August 2025Allow2221YesNo
18134892METHODS AND COMPOSITIONS FOR INDUCING TUMOR CELL DEATHApril 2023October 2024Abandon1801NoNo
18062471SYSTEMS AND METHODS FOR CELL CONVERSIONDecember 2022February 2026Abandon3810NoNo
17914074TARGETING TAPASIN AND TAP COMPLEX TO IMPROVE CELLULAR IMMUNE-COMPATIBILITYSeptember 2022January 2026Abandon4001NoNo
17801736A Method For Providing A Cartilage Implant With ChondrocytesAugust 2022January 2026Abandon4101NoNo
17819547PRECISE TEMPLATE-FREE CORRECTION OF BRCA1 MUTATION IN HUMAN CELLS VIA GENOME EDITINGAugust 2022December 2025Abandon4031NoNo
17782148METHODS OF MEAT PRODUCTION BY IN VITRO CELL CULTIVATIONJune 2022December 2025Abandon4201NoNo
17773080VIABLE PANCREATIC ISLET-LIKE CELL STRUCTURES AND A METHOD OF PREPARING THEREOFApril 2022November 2025Abandon4301NoNo
17770727GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENESApril 2022November 2025Abandon4301NoNo
17720753MODIFIED INDUCED PLURIPOTENT STEM CELL (iPSC) DERIVED MICROGLIA FOR THE TREATMENT OF BRAIN CANCERApril 2022March 2024Abandon2301NoNo
17697168METHOD AND COMPOSITION FOR CHONDROGENESISMarch 2022January 2024Abandon2201NoNo
17761190A METHOD OF ENGINEERING NATURAL KILLER-CELLS TO TARGET BCMA-POSITIVE TUMORSMarch 2022November 2025Abandon4401NoNo
17675895ATRIAL CARDIAC MICROTISSUES FOR CHAMBER-SPECIFIC ARRHYTHMOGENIC TOXICITY RESPONSESFebruary 2022September 2025Abandon4231NoNo
17636235COMPOSITIONS AND METHODS FOR NEUROLOGICAL DISEASESFebruary 2022October 2025Abandon4311NoNo
17631928BIOLOGICAL COMPONENT TREATMENT SYSTEM, BIOLOGICAL COMPONENT TREATMENT DEVICE, AND CELL CULTURING METHODFebruary 2022August 2025Allow4211YesNo
17589840COMPOSITIONS AND METHODS FOR PRODUCING STABLE VIRAL VECTOR PRODUCER CELLS FOR CELL AND GENE THERAPYJanuary 2022September 2025Abandon4410NoNo
17568032METHOD AND COMPOSITION FOR SORTING OUT OF CELL COMPRISING A MODIFIED GENEJanuary 2022August 2023Allow1911NoNo
17555550NON-HUMAN ANIMALS HAVING A HUMANIZED TSLP GENE, A HUMANIZED TSLP RECEPTOR GENE, AND/OR A HUMANIZED IL7RA GENEDecember 2021July 2025Abandon4341NoNo
17539253DECIDUAL PLACENTAL MESENCHYMAL STEM CELL AND THE USE OF THE CELL FOR PREPARING PHARMACEUTICAL COMPOSITIONS FOR PROMOTING ANGIOGENESISDecember 2021February 2024Allow2630NoNo
17525312THERAPEUTIC METHODS AND COMPOSITIONS UTILIZING STROMAL VASCULAR FRACTION DERIVED FROM ADIPOSE TISSUENovember 2021November 2025Allow4831NoNo
17490449RODENT ANIMALS EXPRESSING HUMAN CR1September 2021March 2024Allow2921YesNo
17483100GENETICALLY ENGINEERED T CELLS WITH REGNASE-1 AND/OR TGFBRII DISRUPTION HAVE IMPROVED FUNCTIONALITY AND PERSISTENCESeptember 2021June 2025Abandon4441NoNo
17440488METHOD FOR TREATING ATOPIC DERMATITIS USING MONOCLONAL STEM CELLSSeptember 2021July 2025Abandon4511NoNo
17460120SYNTHETIC MAMMALIAN SIGNALING CIRCUITS FOR ROBUST CELL POPULATION CONTROLAugust 2021January 2024Allow2921YesNo
17409265HUMANIZED MOUSE MODEL SUSCEPTIBLE TO EMERGING CORONAVIRUSESAugust 2021June 2024Abandon3321NoNo
17406723ADENO-ASSOCIATED VIRUS VECTORS FOR TREATMENT OF RETT SYNDROMEAugust 2021May 2024Allow3321YesNo
17377318Synthesis of Non-Native Proteins in Bombyx Mori by Modifying Sericin ExpressionJuly 2021May 2024Abandon3421NoNo
17346948METHODS FOR PRODUCING FIBROADIPOGENIC PROGENITOR CELLSJune 2021October 2024Allow4030NoNo
17326708GENETICALLY ENGINEERED CAR T CELLS THAT SECRETE INTERLEUKIN-12 AND THERAPEUTIC USES THEREOFMay 2021January 2025Abandon4431YesNo
17291667Use of oligodendrocytes from oral neuroectodermal stem cells in the repair of the nervous systemMay 2021April 2024Abandon3611NoNo
17308154HANGING DROP DEVICE, FORMATION METHOD OF HANGING DROP AND CELL CULTURE METHOD BY USING HANGING DROPMay 2021September 2023Allow2821NoNo
17288674METHOD FOR PRODUCING INSULIN-PRODUCING CELLSApril 2021January 2026Abandon5641YesNo
17288253Method for Producing Virus-Infected Cell Line and Animal ModelApril 2021November 2024Abandon4301NoNo
17287480CLEAVABLE ACTIVATORS OF CXCR3 AND METHODS OF USEApril 2021June 2024Allow3821YesNo
17232676COMPOSITIONS AND METHODS FOR SEQUESTERING VIRUSESApril 2021July 2025Abandon5141NoNo
17199115Gene Therapy for NMNAT1-Associated Retinal DegenerationMarch 2021August 2024Allow4140NoNo
17190650A RODENT MODEL OF B4GALT1-MEDIATED FUNCTIONSMarch 2021March 2025Abandon4931YesYes
17270349CELL CLUSTER INCLUDING OLFACTORY NEURON OR PRECURSOR CELL THEREOF, AND METHOD FOR PRODUCING SAMEFebruary 2021July 2024Abandon4011NoNo
17175234HAPLOTYPE-BASED TREATMENT OF RP1 ASSOCIATED RETINAL DEGENERATIONSFebruary 2021June 2024Allow4021YesNo
17173887GENERATING INDUCED PLURIPOTENT STEM CELLSFebruary 2021October 2025Abandon5621NoYes
17161269GENERATION OF INDUCED PLURIPOTENT STEM CELLS (IPSCs) WITH GLUT2 MUTATION OR FOXA2 DELETION, METHODS OF PREPARING SAME, AND METHODS OF USING SAMEJanuary 2021December 2024Allow4741YesNo
17150959INDUCTION OF DNA STRAND BREAKS AT CHROMATIN TARGETSJanuary 2021April 2024Abandon3921NoNo
17150562SINGLE ADENO-ASSOCIATED VIRUS (AAV)-SIZED NUCLEOTIDE FOR USE IN CRISPR INTERFERENCE OR ACTIVATIONJanuary 2021December 2023Allow3530YesNo
17139471PROGRAMMABLE AND PORTABLE CRISPR-CAS TRANSCRIPTIONAL ACTIVATION IN BACTERIADecember 2020July 2023Allow3011NoNo
17136080COMPOSITION AND METHOD FOR PREVENTING OR TREATING EYE DISORDERDecember 2020April 2024Allow3940NoNo
17122087ENGINEERED BI-STABLE TOGGLE SWITCH AND USES THEREOFDecember 2020June 2023Abandon3010NoNo
17119318EXOSOMES ISOLATED FROM MESENCHYMAL STEM CELLS AND USES THEREOFDecember 2020August 2025Allow5651YesNo
17251335METHOD TO GENERATE INDUCED OLIGODENDROCYTE-LINEAGE CELLS AND TREATMENT USING SUCH CELLSDecember 2020October 2025Allow5831YesNo
16973421NEXT GENERATION DESIGNER LIVER ORGANOIDS AND THEIR METHODS OF PREPARATION AND USEDecember 2020December 2024Allow4821YesNo
16972212METHODS FOR GENERATING HEMATOPOIETIC STEM CELLSDecember 2020December 2024Allow4821YesNo
17104231Gene Therapies, Systems, and Methods for MonitoringNovember 2020March 2023Abandon2810NoNo
17104607METHODS AND COMPOSITIONS FOR INDUCING TUMOR CELL DEATHNovember 2020April 2023Abandon2910NoNo
16952267ARTIFICIAL SKELETAL MUSCLE TISSUENovember 2020January 2024Abandon3821NoNo
16951220METHODS FOR ENGINEERING HUMAN PLURIPOTENT STEM CELLS FOR DIABETES THERAPY BY CO-TRANSDUCTIONNovember 2020April 2023Abandon2810NoNo
17094219NEURON CULTIVATION DEVICE, NEURON CULTIVATING METHOD, CULTIVATED NEURON, ANALYSIS AND IDENTIFICATION OF PROTEIN IN AXON BUNDLE, AND USAGE OF CULTIVATED NEURONNovember 2020January 2026Abandon6031YesNo
17093126METHODS OF IN VITRO DIFFERENTIATION OF MIDBRAIN DOPAMINE (MDA) NEURONSNovember 2020May 2024Allow4211YesNo
17091823HYPOXIA-INDUCIBLE FACTOR-2A AS A TARGET IN PREVENTION/TREATMENT OF PARKINSON'S DISEASENovember 2020February 2023Abandon2810NoNo
17050722CRYOPRESERVATION SOLUTION AND CRYOPRESERVATION METHODOctober 2020September 2024Abandon4601NoNo
17049543NON-HUMAN VERTEBRATE COMPRISING HUMAN LIVER CELLS TRANSPLANTED THEREIN AND METHOD FOR PRODUCING THE SAMEOctober 2020January 2026Allow6051YesNo
17048906GENERATION OF HUMAN ENDODERMAL ORGANS IN PIG MODEL USING LINEAGE RESTRICTED ENDODERMAL PRECURSORSOctober 2020July 2025Abandon5721NoNo
17072637AAV TRANSFER CASSETTEOctober 2020January 2026Allow6061NoNo
17071095VARIANTS OF CAS12A NUCLEASES AND METHODS OF MAKING AND USE THEREOFOctober 2020October 2023Allow3630YesNo
17046468SENSOR FUNCTIONALISED BIOINKOctober 2020July 2024Abandon4601NoNo
17046248CULTURE SCAFFOLD FOR PROMOTING STEM CELL DIFFERENTIATION COMPRISING MULTILAYER GRAPHENE FILMOctober 2020September 2025Allow6031YesNo
17045308DRUG SCREENING PLATFORM USING BIOMATERIAL SCAFFOLDSOctober 2020March 2024Abandon4211NoNo
17043229DIFFERENTIATION MEDIUM AND METHOD FOR PREPARING OLIGODENDROCYTE PRECURSORSeptember 2020July 2024Abandon4621NoNo
17041677METHODS OF MODULATING ANTISENSE ACTIVITYSeptember 2020January 2025Abandon5220NoNo
17028139MULTIPLEXABLE CRISPR EDITORS UTILIZING INTRACELLULAR EVOLVED APTAMERS FOR ENDOGENOUS EFFECTOR RECRUITMENTSeptember 2020March 2025Abandon5441YesYes
16948450CANINE EPITHELIAL ORGANOIDS AND METHODS OF MAKING, RECOVERING, AND USESeptember 2020January 2026Abandon6071YesNo
17011292Humanized Knock-In Mouse Expressing Human Protein C.September 2020October 2023Allow3721NoNo
17001590HUMANIZED VIPR2 COPY NUMBER VARIANT TRANSGENIC MOUSE MODEL FOR ANTIPSYCHOTIC DRUG AND GENE THERAPY DISCOVERY FOR SCHIZOPHRENIAAugust 2020April 2024Abandon4330NoNo
16965835ACTIVATION-INDUCED TISSUE-EFFECTOR CELLS SUITABLE FOR CELL THERAPY AND EXTRACELLUAR VESICLES DERIVED THEREFROMJuly 2020June 2025Abandon5921NoNo
16960812EFFICIENT DERIVATION OF STABLE PLURIPOTENT BOVINE EMBRYONIC STEM CELLSJuly 2020October 2025Allow6031YesNo
16833099METHOD OF TREATING OR PREVENTING HERNIA FORMATIONMarch 2020January 2024Allow4650YesNo
16629485BIOSENSORS FOR MEASURING CELL SIGNALING IN STRESSED AND HEALTHY CELLSJanuary 2020February 2024Abandon4911NoNo
16626227TRANSGENIC ANIMALS AND TRANSGENIC EMBRYOS PRODUCING AN ENGINEERED NUCLEASEDecember 2019April 2024Allow5230YesNo
16622739Genome Editing System For Repeat Expansion MutationDecember 2019May 2024Abandon5340YesNo
16622509UNIVERSAL SELF-REGULATING MAMMALIAN CELL LINE PLATFORM FOR THE PRODUCTION OF BIOLOGICSDecember 2019March 2024Allow5121YesNo
16491208COMPOSITION CONTAINING C2CL ENDONUCLEASE FOR DIELECTRIC CALIBRATION AND METHOD FOR DIELECTRIC CALIBRATION USING SAMEDecember 2019April 2023Abandon4320NoNo
16703036METHOD FOR PREPARING DIFFERENTIATION-INDUCED CELLSDecember 2019October 2025Abandon6070YesNo
16616216CELL CRYOPRESERVATION FORMULATION AND CELL RECOVERY METHODNovember 2019February 2025Abandon6070NoNo
16615854VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR 21 (FGF21) CODING SEQUENCENovember 2019December 2023Abandon4921NoNo
16687426HIGH ACTIVITY REGULATORY ELEMENTSNovember 2019June 2024Allow5531YesNo
16604785New Uses Of Mammalian Muscle-Derived Stem CellsOctober 2019February 2024Abandon5340YesNo
16484506FLUIDIC CHIP FOR CELL CULTURE USE, CULTURE VESSEL, AND CULTURE METHODAugust 2019October 2023Allow5021YesNo
16527152EARLY-ONSET PARKINSON'S DISEASE MODEL: (D331Y) PLA2G6 KNOCKIN MODEL, PLATFORM AND METHOD FOR DRUG SCREENING, AND KIT OF DETECTIONJuly 2019June 2024Abandon5831NoNo
16503481Preparation and application of immortalized alpha-1,3-galactosyltransferase gene knockout pig hepatocyte cell lineJuly 2019May 2023Abandon4711NoNo
15960048PROMOTERS, EXPRESSION CASSETTES, VECTORS, KITS, AND METHODS FOR THE TREATMENT OF ACHROMATOPSIA AND OTHER DISEASESApril 2018May 2024Abandon6061NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner DHAR, MATASHA.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
1
Examiner Affirmed
1
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.4%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
3
Allowed After Appeal Filing
0
(0.0%)
Not Allowed After Appeal Filing
3
(100.0%)
Filing Benefit Percentile
0.4%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 0.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner DHAR, MATASHA - Prosecution Strategy Guide

Executive Summary

Examiner DHAR, MATASHA works in Art Unit 1632 and has examined 71 patent applications in our dataset. With an allowance rate of 42.3%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 46 months.

Allowance Patterns

Examiner DHAR, MATASHA's allowance rate of 42.3% places them in the 8% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by DHAR, MATASHA receive 2.68 office actions before reaching final disposition. This places the examiner in the 78% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by DHAR, MATASHA is 46 months. This places the examiner in the 10% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +48.0% benefit to allowance rate for applications examined by DHAR, MATASHA. This interview benefit is in the 92% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 19.6% of applications are subsequently allowed. This success rate is in the 20% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 22.5% of cases where such amendments are filed. This entry rate is in the 29% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 0.0% of appeals filed. This is in the 0% percentile among all examiners. Strategic Insight: This examiner rarely withdraws rejections during the appeal process compared to other examiners. If you file an appeal, be prepared to fully prosecute it to a PTAB decision. Per MPEP § 1207, the examiner will prepare an Examiner's Answer maintaining the rejections.

Petition Practice

When applicants file petitions regarding this examiner's actions, 84.6% are granted (fully or in part). This grant rate is in the 86% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 1% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 1% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.