USPTO Examiner JEAN LOUIS SAMIRA JM - Art Unit 1627

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
17126347USE OF AN RXR AGONIST IN TREATING HER2+ CANCERSDecember 2020September 2021Allow920NoNo
17108728Methods for Treating EGFR Mutant CancersDecember 2020November 2023Abandon3510NoNo
17097193HISTONE DEMETHYLASE INHIBITORSNovember 2020September 2023Allow3410NoNo
17088466PYRIDAZINONE COMPOUNDS AND USES THEREOFNovember 2020August 2021Allow1011YesNo
17052162INHIBITORS OF CYCLIN-DEPENDENT KINASESOctober 2020May 2022Allow1810NoNo
17080425AMIDE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS AND METHODS OF TREATMENTOctober 2020September 2022Allow2321YesNo
17050747OXO-SUBSTITUTED COMPOUNDOctober 2020January 2023Allow2711YesNo
17079152INHIBITORS OF RAF KINASESOctober 2020January 2021Allow301NoNo
17074002USE OF OPIOID ANTAGONISTSOctober 2020December 2023Abandon3801NoNo
17073615SMALL MOLECULE INHIBITORS OF STAT3 WITH ANTI-TUMOR ACTIVITYOctober 2020October 2023Abandon3601NoNo
17073253LASOFOXIFENE TREATMENT OF BREAST CANCEROctober 2020December 2023Abandon3811NoNo
17071949ACRYLOYL-CONTAINING NUCLEAR TRANSPORT REGULATORS AND USES THEREOFOctober 2020January 2022Allow1510YesNo
17070556COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KITOctober 2020July 2023Abandon3321NoNo
17047178PROCESS FOR PREPARING MODULATORS OF P300 AND/OR CBPOctober 2020July 2022Allow2210NoNo
17047002QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOFOctober 2020June 2023Allow3231NoNo
17044007Compounds and Their Use as PDE4 ActivatorsSeptember 2020September 2022Allow2320YesNo
17043217CRYSTALLINE FORMS OF MODULATORS OF CFTRSeptember 2020October 2023Abandon3710NoNo
170427564-(3-AMINO-6-FLUORO-1H-INDAZOL-5-YL)-1,2,6-TRIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DIC ARBONITRILE COMPOUNDS FOR TREATING HYPERPROLIFERATIVE DISORDERSSeptember 2020July 2022Abandon2110NoNo
17029835TARGETED THERAPEUTICSSeptember 2020September 2023Abandon3601NoNo
17023778NEUROMODULATING COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCERSeptember 2020May 2023Abandon3211NoNo
17020062Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the SameSeptember 2020October 2022Allow2520YesNo
17020555IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOFSeptember 2020January 2021Allow411YesNo
17015319COMPOUNDS TARGETING AND DEGRADING BCR-ABL PROTEIN AND ITS ANTITUMOR APPLICATIONSeptember 2020November 2022Allow2611YesNo
16979457TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORSSeptember 2020February 2022Allow1710YesNo
17012788TRICYCLIC KINASE INHIBITORS AND USE THEREOFSeptember 2020April 2022Abandon2010NoNo
17001400TREATMENT OF SCHIZOPHRENIAAugust 2020October 2023Abandon3711NoNo
16998731COMPOSITIONS AND KITS FOR OMEPRAZOLE SUSPENSIONAugust 2020May 2023Allow3210YesNo
16989685THERAPIES FOR HEMATOLOGIC MALIGNANCIESAugust 2020March 2022Abandon1920NoNo
16968429ATR INHIBITOR AND APPLICATION THEREOFAugust 2020April 2022Allow2010YesNo
16945039NOVEL CONFORMATIONALLY-RESTRICTED ANALOGUES OF SORAFENIB AND REGORAFENIB AS SELECTIVE KINASE INHIBITORS FOR CANCER TREATMENTJuly 2020March 2022Allow2010YesNo
16964274Compounds for the Treatment of Kinase-Dependent DisordersJuly 2020January 2023Allow2911NoNo
16931786PYRIDINE AND PYRIMIDINE DERIVATIVESJuly 2020January 2022Allow1810NoNo
16930581Microbicidal Pyrimidine or Triazine Containing CompoundsJuly 2020March 2023Abandon3231YesNo
16962724Compounds for Treating Rac-GTPase Mediated DisorderJuly 2020February 2023Allow3120YesNo
16928927Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative StressJuly 2020June 2023Allow3521YesNo
16926035HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTSJuly 2020September 2022Abandon2711NoNo
16961190TETRAHYDROISOQUINOLINE COMPOUNDSJuly 2020May 2022Allow2320YesNo
16924082METHODS OF TREATING VIRALLY ASSOCIATED CANCERS WITH HISTONE DEACETYLASE INHIBITORSJuly 2020February 2021Allow710YesNo
16914703FORMULATIONS OF MILCICLIB AND THERAPEUTIC COMBINATIONS OF THE SAME FOR USE IN THE TREATMENT OF CANCERJune 2020November 2023Abandon4131NoNo
16958711N-ALKYL-N-CYANOALKYLBENZAMIDE COMPOUND AND USE THEREOFJune 2020March 2022Allow2010YesNo
16909128HEST G-18-0 AND BENZOYL PEROXIDE COMPOSITIONS AND METHODS FOR USING THE SAMEJune 2020April 2022Allow2120NoNo
16955491PYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCERJune 2020March 2023Abandon3301NoNo
16903965METHODS AND COMPOSITIONS FOR TREATING FATIGUE ASSOCIATED WITH DISORDERED SLEEP USING VERY LOW DOSE CYCLOBENZAPRINEJune 2020October 2023Abandon4030NoNo
16954552CYCLOHEXYL ACID ISOXAZOLE AZINES AS LPA ANTAGONISTSJune 2020December 2021Allow1810YesNo
16954501PROCESS FOR THE PREPARATION OF OPICAPONE AND INTERMEDIATES THEREOFJune 2020December 2022Abandon3011NoNo
16954325CYCLOHEXYL ACID PYRAZOLE AZINES AS LPA ANTAGONISTSJune 2020December 2021Allow1810YesNo
16772842CYCLOHEXYL ACID TRIAZOLE AZOLES AS LPA ANTAGONISTSJune 2020December 2021Allow1810YesNo
16898920PHARMACOTHERAPY FOR PREVENTING OR TREATING GLAUCOMAJune 2020October 2021Abandon1610NoNo
16897987NOVEL INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER CONTAINING THE SAMEJune 2020March 2022Allow2110NoNo
16898230USE OF AN RXR AGONIST IN TREATING HER2+ CANCERSJune 2020December 2020Allow610YesNo
16896663Methods, Compositions, and Uses of Novel FYN Kinase InhibitorsJune 2020February 2023Allow3320YesNo
16893750THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USEJune 2020December 2022Allow3021NoNo
16890035Prodrug Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of UseJune 2020January 2022Allow2010NoNo
16886276Indolyl-Pyridone Derivatives Having Checkpoint Kinase 1 Inhibitory ActivityMay 2020June 2022Abandon2401NoNo
16883985INHIBITORS OF CAMKK2 AND USES OF SAMEMay 2020March 2022Allow2211YesNo
16881373COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERSMay 2020August 2022Abandon2721NoNo
16762685SELENOPSAMMAPLIN A AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING CANCER, CONTAINING SAME AS ACTIVE INGREDIENTSMay 2020January 2023Allow3320YesNo
16870572Methods for the Administration of Certain VMAT2 InhibitorsMay 2020April 2021Allow1131YesNo
16870423Methods for the Administration of Certain VMAT2 InhibitorsMay 2020February 2021Allow921NoNo
16870823Methods for the Administration of Certain VMAT2 InhibitorsMay 2020March 2021Allow1030NoNo
16863459Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for SameApril 2020November 2022Abandon3111NoNo
16862608Solid Forms of a GlyT1 InhibitorApril 2020April 2022Allow2411NoNo
16859413PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAMEApril 2020October 2021Allow1810NoNo
16858116HETEROCYCLIC INHIBITORS OF TYROSINE KINASEApril 2020February 2022Allow2220YesNo
16855712RET INHIBITORApril 2020December 2022Allow3220NoNo
16855213THERAPEUTIC DRUG FOR DYSKINESIAApril 2020March 2022Abandon2310NoNo
16851648FUROSTAN-3-OL DERIVATIVES AS SKELETAL MUSCLE HYPERTROPHIC AGENTSApril 2020August 2021Allow1610NoNo
16754821METHOD FOR PREPARING 3-[(4S)-8-BROMO-1-METHYL-6-(PYRIDIN-2-YL)-4H-IMIDAZO[1,2-A][1,4]BENZODIAZEPIN-4-YL]-PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN SAID METHODApril 2020February 2022Allow2211NoNo
16652780HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS AND METHODS OF USING THE SAMEApril 2020February 2022Abandon2310NoNo
16835719PHARMACEUTICAL COMPOSITION FOR TREATING TUMORMarch 2020January 2021Allow1010YesNo
16834543METHODS OF TREATING AGE-RELATED SYMPTOMS IN MAMMALS AND COMPOSITIONS THEREFORMarch 2020August 2022Abandon2920NoNo
168295971,2,3-TRIAZOLE DERIVATIVES AND USES THEREOFMarch 2020December 2021Abandon2110NoNo
16649717CRBN LIGANDS AND USES THEREOFMarch 2020February 2022Allow2311YesNo
16824885NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPTMarch 2020October 2021Allow1910NoNo
16824443TARGETING GLIOBLASTOMA STEM CELLS THROUGH THE TLX-TET3 AXISMarch 2020July 2022Abandon2811NoNo
16648737COMPOSITIONS AND METHODS OF REDUCING SERUM CHOLESTEROL AND PCSK9March 2020October 2022Allow3011YesNo
16821098QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOFMarch 2020March 2022Allow2411YesNo
16816132HETEROCYCLIC COMPOUNDS AND USES THEREOFMarch 2020August 2022Allow2921NoNo
16799956COMPOSITION FOR TREATING OCULAR DISORDERS SUCH AS MACULAR DEGENERATION, RETINOPATHY AND GLAUCOMAFebruary 2020December 2021Abandon2210NoNo
16797081PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLINGFebruary 2020March 2023Abandon3721NoNo
16639964SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORSFebruary 2020March 2022Allow2420YesNo
16639646Chemical Compound, Pharmaceutical Composition Thereof, and Use and Application ThereofFebruary 2020December 2021Abandon2210NoNo
16790197Pharmaceutical Compositions and Their Use for Treatment of Cancer and Autoimmune DiseasesFebruary 2020February 2022Allow2411NoNo
16789724DERMATOLOGICAL COMPOSITIONS AND METHODSFebruary 2020November 2020Abandon910NoNo
16781964TREATMENT OF CANCER WITH SPECIFIC RXR AGONISTSFebruary 2020December 2020Allow1120YesNo
16776984DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIAJanuary 2020January 2023Allow3621YesNo
16776190METHOD OF INCREASING MELATONIN SYNTHESIS TO TREAT INSOMNIA, AMELIORATE SLEEP DISTURBANCE AND REGULATE SLEEPJanuary 2020December 2020Allow1020YesNo
16739948METHODS AND COMPOSITIONS FOR THE TREATMENT OF RETINOPATHY AND OTHER OCULAR DISEASESJanuary 2020September 2022Allow3321NoNo
16739873METHODS AND COMPOSITIONS FOR THE TREATMENT OF RETINOPATHY AND OTHER OCULAR DISEASESJanuary 2020September 2022Allow3321NoNo
16738103COMBINATION THERAPY WITH AXL INHIBITOR AND IMMUNE CHECKPOINT MODULATOR OR ONCOLYTIC VIRUSJanuary 2020February 2022Allow2511YesNo
16736705TREATMENT OF DISEASES BY CONCURRENTLY ELICITING REMYELINATION EFFECTS AND IMMUNOMODULATORY EFFECTS USING SELECTIVE RXR AGONISTSJanuary 2020September 2022Abandon3311NoNo
16728566APILIMOD COMPOSITIONS AND METHODS FOR USING SAMEDecember 2019October 2021Allow2210NoNo
16703180Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor AgentsDecember 2019May 2021Allow1710NoNo
16700522TRICYCLIC SPIRO COMPOUNDDecember 2019August 2021Allow2011YesNo
16697611METHODS AND COMPOSITIONS FOR THE TREATMENT OF RETINOPATHY AND OTHER OCULAR DISEASESNovember 2019May 2022Allow3021NoNo
16695814APILIMOD COMPOSITIONS AND METHODS FOR USING SAME IN THE TREATMENT OF RENAL CANCERNovember 2019May 2021Allow1810NoNo
16617471COMPOSITIONS FOR THE TREATMENT OF FIBROSISNovember 2019March 2023Allow3941YesNo
16689965COMBINATION THERAPY FOR HEAD AND NECK CANCERNovember 2019December 2023Abandon4941NoNo
16678988METHODS FOR SHRINKING PITUITARY TUMORSNovember 2019February 2021Allow5720NoNo
16675669PHARMACEUTICALLY ACCEPTABLE SALTS OF BETA-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOFNovember 2019April 2022Abandon2921NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner JEAN-LOUIS, SAMIRA JM.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
13
Examiner Affirmed
9
(69.2%)
Examiner Reversed
4
(30.8%)
Reversal Percentile
48.3%
Lower than average

What This Means

With a 30.8% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
92
Allowed After Appeal Filing
17
(18.5%)
Not Allowed After Appeal Filing
75
(81.5%)
Filing Benefit Percentile
23.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 18.5% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner JEAN-LOUIS, SAMIRA JM - Prosecution Strategy Guide

Executive Summary

Examiner JEAN-LOUIS, SAMIRA JM works in Art Unit 1627 and has examined 980 patent applications in our dataset. With an allowance rate of 51.9%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 30 months.

Allowance Patterns

Examiner JEAN-LOUIS, SAMIRA JM's allowance rate of 51.9% places them in the 15% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by JEAN-LOUIS, SAMIRA JM receive 1.73 office actions before reaching final disposition. This places the examiner in the 34% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by JEAN-LOUIS, SAMIRA JM is 30 months. This places the examiner in the 58% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +55.8% benefit to allowance rate for applications examined by JEAN-LOUIS, SAMIRA JM. This interview benefit is in the 95% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 24.1% of applications are subsequently allowed. This success rate is in the 38% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 49.2% of cases where such amendments are filed. This entry rate is in the 74% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 50.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 43% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 75.9% of appeals filed. This is in the 67% percentile among all examiners. Of these withdrawals, 61.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 71.3% are granted (fully or in part). This grant rate is in the 77% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 1.0% of allowed cases (in the 67% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 8.3% of allowed cases (in the 88% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.