USPTO Examiner KIFLE BRUCK - Art Unit 1624

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18973867N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATIONDecember 2024May 2025Allow610NoNo
18927756BENZOTRIAZOLE COMPOUNDOctober 2024March 2025Allow510NoNo
18832305PROCESS FOR THE RECOVERY OF EPSILON-CAPROLACTAM FROM POLYAMIDE 6 COMPRISING FISHING NETSJuly 2024March 2025Allow800NoNo
18651408C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR InhibitorsApril 2024May 2025Allow1300NoNo
18650894TOPICAL PHARMACEUTICAL COMPOSITION IN THE FORM OF AQUEOUS GEL COMPRISING AT LEAST AMITRIPTYLINEApril 2024October 2024Allow610NoNo
18650932TOPICAL PHARMACEUTICAL COMPOSITION IN THE FORM OF AQUEOUS GEL COMPRISING AT LEAST AMITRIPTYLINEApril 2024October 2024Allow610NoNo
18621266RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAMEMarch 2024June 2025Abandon1410NoNo
18607834HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDSMarch 2024May 2025Abandon1410NoNo
18688914COUPLED UREA MELAMINE PRODUCTION WITH HP CO2 STRIPPINGMarch 2024July 2024Allow400NoNo
18592808RAS INHIBITORSMarch 2024April 2025Allow1320NoNo
18584520Benzodiazepine Derivatives as RSV InhibitorsFebruary 2024December 2024Allow1010NoNo
18582548CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USEFebruary 2024March 2025Abandon1310NoNo
18444006Compounds for the Treatment of Alzheimer's DiseaseFebruary 2024May 2025Allow1511NoNo
18430498AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORSFebruary 2024March 2025Allow1310NoNo
18423596TREATMENT OF BREAST CANCER USING COMBINATION THERAPIES COMPRISING GDC-9545 AND A CDK4/6 INHIBITORJanuary 2024January 2025Allow1210NoNo
18410925IMIDAZO[1,5-A]PYRAZINE DERIVATIVES AS PI3Kdelta INHIBITORSJanuary 2024March 2025Abandon1410NoNo
18388776HETEROCYCLIC COMPOUNDSNovember 2023April 2025Allow1720NoNo
18236095POLYMORPHS OF SEPIAPTERIN AND SALTS THEREOFAugust 2023December 2024Allow1610NoNo
18232435Compounds, Compositions and MethodsAugust 2023March 2025Allow1920NoNo
18227561DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASESJuly 2023April 2025Allow2101NoNo
18359467SYNTHESIS OF OMECAMTIV MECARBILJuly 2023August 2024Allow1300NoNo
18345686COMPOSITIONS AND METHODS FOR TREATING CANCERJune 2023June 2025Abandon2411NoNo
18343319HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOFJune 2023February 2025Allow2011NoNo
18211314NLRX1 LIGANDSJune 2023November 2024Abandon1710NoNo
18209939SYNTHESIS OF A BRUTON'S TYROSINE KINASE INHIBITORJune 2023April 2024Allow1000NoNo
18329681PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOFJune 2023August 2024Allow1410NoNo
18326344NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USEMay 2023September 2024Allow1620NoNo
18199275COMPOUNDS AS NUCLEAR TRANSPORT MODULATORS AND USES THEREOFMay 2023October 2024Allow1710NoNo
18306191TUBULIN BINDING COMPOUNDS AND THERAPEUTIC USE THEREOFApril 2023April 2025Allow2311NoNo
18181336MCL-1 INHIBITORSMarch 2023July 2024Allow1610NoNo
18181116MCL1 INHIBITORSMarch 2023August 2024Allow1710NoNo
18176335mTORC1 INHIBITORSFebruary 2023May 2024Allow1400NoNo
18176362IRE1 SMALL MOLECULE INHIBITORSFebruary 2023April 2024Allow1410NoNo
18111453POLYCYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORSFebruary 2023October 2024Abandon2001NoNo
18170319MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORSFebruary 2023November 2024Abandon2110NoNo
18162052METHODS FOR ANTAGONIZING A MELANOCORTIN 4 RECEPTORJanuary 2023August 2024Allow1810NoNo
18162250SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STINGJanuary 2023February 2025Abandon2520NoNo
18161266RAS INHIBITORSJanuary 2023December 2023Allow1000NoNo
18101362COMPOUND WITH ANTICANCER ACTIVITYJanuary 2023March 2024Allow1410NoNo
18099311PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERSJanuary 2023June 2024Allow1710NoNo
18098834METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVESJanuary 2023November 2024Abandon2210NoNo
18149992METHOD FOR TREATING PULMONARY ARTERIAL HYPERTENSION AND ASSOCIATED PULMONARY ARTERIAL HYPERTENSION AND DAILY DOSINGJanuary 2023October 2024Abandon2110NoNo
18082195DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USEDecember 2022November 2024Abandon2301NoNo
18080973METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVESDecember 2022November 2024Abandon2310NoNo
18061822TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOFDecember 2022February 2024Allow6010NoNo
18058220ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDSNovember 2022April 2025Allow2811NoNo
18057589COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITYNovember 2022October 2024Abandon2301NoNo
18056227PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORSNovember 2022February 2024Allow1520YesNo
18052096COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINSNovember 2022August 2024Allow2110NoNo
18051762COMPOUNDS FOR TREATING ILK-MEDIATED DISEASESNovember 2022June 2024Allow1910NoNo
17976267Compounds for the Treatment of Cancer and Inflammatory DiseaseOctober 2022July 2024Allow2120NoNo
17973209CYTOTOXIC BENZODIAZEPINE DERIVATIVESOctober 2022October 2024Abandon2310NoNo
17962938CompoundsOctober 2022October 2024Allow2411NoNo
17959144N/O-Linked Degrons and Degronimers for Protein DegradationOctober 2022August 2024Allow2211NoNo
17931814COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINSSeptember 2022November 2024Allow2620NoNo
17902432INHIBITORS OF THE MENIN-MLL INTERACTIONSeptember 2022February 2025Allow3011NoNo
17881222INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATIONAugust 2022August 2024Abandon2410NoNo
17872855METHODS OF PREVENTING CANCER METASTASISJuly 2022February 2024Allow1810NoNo
17871201P2X4 RECEPTOR ANTAGONISTJuly 2022May 2024Allow2210NoNo
17870303NOVEL 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVEJuly 2022December 2023Allow1710NoNo
17865192NOVEL HETEROCYCLIC COMPOUNDSJuly 2022August 2023Allow1310NoNo
17792741BENZO[5,6][1,4]DIOXINO[2,3-B]PYRIDINE COMPOUNDS USEFUL AS IRAK4 INHIBITORSJuly 2022June 2025Allow3610NoNo
17811050COMPOSITION FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARYDISEASE COMPRISING REGORAFENIB AS ACTIVE INGREDIENTJuly 2022November 2023Allow1610NoNo
17810922HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7July 2022October 2024Allow2711NoNo
17843194RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAMEJune 2022August 2024Abandon2620NoNo
17841046METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVESJune 2022January 2024Allow1910NoNo
17841026METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVESJune 2022January 2024Allow1910NoNo
17836060POLYMORPHIC FORMS OF METOPIMAZINEJune 2022August 2023Allow1500NoNo
17833272PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOFJune 2022April 2024Allow2210NoNo
17782244METHOD FOR PRODUCING LAUROLACTAM, DEVICE FOR SYNTHESIZING SAME, LAUROLACTAM COMPOSITION PRODUCED THEREBY, AND METHOD FOR PRODUCING POLYLAUROLACTAM USING SAMEJune 2022June 2025Allow3611NoNo
17828832ESTROGEN RECEPTOR-MODULATING COMPOUNDSMay 2022February 2024Allow2011NoNo
17748484ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAMEMay 2022December 2023Allow1910YesNo
17746038RIFAXIMINMay 2022March 2024Abandon2210NoNo
17738370SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORSMay 2022December 2023Allow1910NoNo
17735386N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2BMay 2022June 2024Allow2620YesNo
17735258BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORSMay 2022November 2023Allow1910NoNo
17733755C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR InhibitorsApril 2022March 2024Allow2220NoNo
17720472Inhibitors of Beta-Hydoxylase for Treatment of CancerApril 2022June 2024Abandon2610NoNo
17719433URACIL DERIVATIVES AS TRPA1 INHIBITORSApril 2022July 2023Allow1510NoNo
17715935P-PHENYLENEDIAMINE DERIVATIVE AS POTASSIUM CHANNEL REGULATOR AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOFApril 2022July 2024Allow2720NoNo
17712541LYSYL OXIDASE INHIBITORSApril 2022March 2024Allow2410NoNo
17710485NOOTKATONE DERIVATIVES AND METHODS OF USING THE SAMEMarch 2022December 2023Allow2020NoNo
17709021PYRIDOPYRIMIDINONE COMPOUNDSMarch 2022November 2023Abandon1910NoNo
17754118HETEROCYCLIC COMPOUND AND USE THEREOFMarch 2022December 2023Allow2120NoNo
17697275PREPARATION OF SUBSTITUTED DIAMINOPYRAZINE DICARBOXYLIC ACIDSMarch 2022February 2025Allow3510NoNo
176925363-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTSMarch 2022March 2024Allow2521NoNo
17691862MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVESMarch 2022July 2024Allow2820NoNo
17691658CRYSTALLINE SALT OF A MULTI-TYROSINE KINASE INHIBITOR, METHOD OF PREPARATION, AND USE THEREOFMarch 2022May 2023Allow1510NoNo
17641606METHODS AND MATERIALS FOR INCREASING LEVEL OF PHOSPHORYLATED AMPK PROTEINMarch 2022March 2025Allow3711NoNo
17675453PLINABULIN COMPOSITIONSFebruary 2022February 2024Allow2410NoNo
17592679BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENTFebruary 2022February 2024Allow2510NoNo
17582774FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASEJanuary 2022February 2023Allow1200NoNo
17625244Compounds And Methods For Treating Fibrotic PathologiesJanuary 2022December 2024Allow3610NoNo
17568530ETHYNYL DERIVATIVESJanuary 2022July 2024Allow3020NoNo
17564850COMPOUND, COMPOSITIONS, AND METHODSDecember 2021April 2024Abandon2801NoNo
17563351Protein Kinase C Beta Inhibitors and Uses ThereofDecember 2021May 2024Abandon2930NoNo
17561032DEGRADATION OF CYCLIN-DEPENDENT KINASE 8 (CDK8) BY CONJUGATION OF CDK8 INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USEDecember 2021July 2023Allow1900NoNo
17552649Thermally Activated Delayed Fluorescent Material Based on 9,10-Dihydro-9,9-dimethylacridine Analogues for Prolonging Device LongevityDecember 2021February 2024Allow2610NoNo
17547967MODULATORS OF TMEM16A FOR TREATING RESPIRATORY DISEASEDecember 2021March 2025Allow3911NoNo
17541924Methods and compositions for the treatment of IL13Ra2- overexpressing cancerDecember 2021August 2023Allow2110NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner KIFLE, BRUCK.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
3
Examiner Affirmed
3
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.2%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
100
Allowed After Appeal Filing
53
(53.0%)
Not Allowed After Appeal Filing
47
(47.0%)
Filing Benefit Percentile
83.8%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 53.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the top 25% across the USPTO, indicating that filing appeals is particularly effective here. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner KIFLE, BRUCK - Prosecution Strategy Guide

Executive Summary

Examiner KIFLE, BRUCK works in Art Unit 1624 and has examined 1,899 patent applications in our dataset. With an allowance rate of 81.9%, this examiner has a below-average tendency to allow applications. Applications typically reach final disposition in approximately 19 months.

Allowance Patterns

Examiner KIFLE, BRUCK's allowance rate of 81.9% places them in the 47% percentile among all USPTO examiners. This examiner has a below-average tendency to allow applications.

Office Action Patterns

On average, applications examined by KIFLE, BRUCK receive 1.44 office actions before reaching final disposition. This places the examiner in the 33% percentile for office actions issued. This examiner issues fewer office actions than average, which may indicate efficient prosecution or a more lenient examination style.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by KIFLE, BRUCK is 19 months. This places the examiner in the 91% percentile for prosecution speed. Applications move through prosecution relatively quickly with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +14.8% benefit to allowance rate for applications examined by KIFLE, BRUCK. This interview benefit is in the 57% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 35.1% of applications are subsequently allowed. This success rate is in the 73% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 71.3% of cases where such amendments are filed. This entry rate is in the 91% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 57.1% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 46% percentile among all examiners. Note: Pre-appeal conferences show below-average success with this examiner. Consider whether your arguments are strong enough to warrant a PAC request.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 95.7% of appeals filed. This is in the 84% percentile among all examiners. Of these withdrawals, 74.2% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 52.8% are granted (fully or in part). This grant rate is in the 66% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 7.6% of allowed cases (in the 93% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.6% of allowed cases (in the 51% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.