USPTO Examiner RAMOS LEWIS JOSMALEN MILAGROS - Art Unit 1621

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19224188SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTIONMay 2025January 2026Allow810NoNo
19198458THERAPEUTIC METHODS AND COMPOSITIONS FOR TREATING MOVEMENT DISORDERSMay 2025February 2026Allow1010NoNo
19189146FIVE-MEMBERED RING-FUSED SIX-MEMBERED RING COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOFApril 2025January 2026Allow910NoNo
19034407SUBSTITUTED DERIVATIVES OF ISOINDOLESJanuary 2025September 2025Allow821YesNo
19020085INHIBITORS OF KIF18A AND USES THEREOFJanuary 2025June 2025Allow501NoNo
18977370SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTIONDecember 2024April 2025Allow410NoNo
18971536NOVEL DRP-1 INHIBITORS AS THERAPEUTIC AGENTSDecember 2024August 2025Allow811NoNo
18907296TOPICAL OCULAR DELIVERY OF CROMAKALIMOctober 2024January 2026Allow1620NoNo
18907300TOPICAL OCULAR DELIVERY OF CROMAKALIMOctober 2024January 2026Allow1620YesNo
18823214PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFORSeptember 2024March 2025Allow601NoNo
18655062THERAPEUTIC METHODS AND COMPOSITIONS FOR TREATING MOVEMENT DISORDERSMay 2024March 2025Allow1011YesNo
18651214FIVE-MEMBERED RING-FUSED SIX-MEMBERED RING COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOFApril 2024March 2025Allow1111NoNo
187024855 ALPHA DIHYDROTESTOSTERONE FORMULATIONS AND ASSOCIATED METHODS OF USE AND TREATMENTApril 2024March 2025Allow1130YesNo
18589461PRMT5 INHIBITING COMPOUNDS AND USES THEREOFFebruary 2024March 2025Allow1211YesNo
18433879NOVEL DRP-1 INHIBITORS AS THERAPEUTIC AGENTSFebruary 2024October 2024Allow911NoNo
18412741SELECTIVE HYPOXIA INDUCIBLE FACTOR PROLYL-HYDROXYLASE INHIBITORSJanuary 2024June 2024Allow500NoNo
18395334EP2 ANTAGONIST COMPOUNDSDecember 2023January 2026Allow2521YesNo
18522287NOVEL CRYSTAL FORM F OF TRELAGLIPTIN AND PREPARATION METHOD THEREOFNovember 2023February 2025Allow1500NoNo
18209119ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USEJune 2023April 2025Allow2201NoNo
18164346HETEROCYCLIC COMPOUNDS AND METHODS OF USEFebruary 2023May 2025Allow2701NoNo
18164277Solid forms of 1-((S)-4-((R)-7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-oneFebruary 2023October 2025Allow3311YesNo
18162821TREATMENT OF OVARIAN CANCER WITH NIROGACESTATFebruary 2023November 2025Abandon3330NoNo
18160082PARP7 INHIBITORSJanuary 2023December 2024Allow2211NoNo
18154810METHODS AND COMPOSITIONS FOR TREATMENT OF SOLID TUMORSJanuary 2023July 2025Abandon3020NoNo
17981306Canker sore preparation for the treatment of canker sore.November 2022May 2024Abandon1810NoNo
17932386DIPHENYL THIOUREA AND DIPHENYL UREA DERIVATIVES AS INHIBITORS OF ENDOCYTOSISSeptember 2022June 2025Abandon3331NoNo
17874838Composition Of Ferric Maltol For Oral AdministrationJuly 2022April 2025Allow3330NoNo
17866382PREVENTION OF THE CONVERSION OF PHARMACEUTICAL AGENTS INTO TOXIC N-NITROSAMINE COMPOUNDSJuly 2022December 2024Abandon2911NoNo
17787207PROCESS FOR THE PREPARATION OF A CHIRAL PROSTAGLANDIN ENOL INTERMEDIATE AND INTERMEDIATE COMPOUNDS USEFUL IN THE PROCESSJune 2022September 2024Allow2721YesNo
17636133PHARMACEUTICAL COMPOSITION FOR TREATING INSOMNIAFebruary 2022December 2025Abandon4501NoNo
17548269MODULATING BONE MORPHOGENIC PROTEIN (BMP) SIGNALING IN THE TREATMENT OF ALZHEIMER'S DISEASEDecember 2021February 2024Abandon2611YesNo
17540269ANTIMICROBIAL COMPOSITION COMPRISING MALEIC ACID/VINYL ETHER COPOLYMERDecember 2021November 2024Abandon3621YesNo
17598187A SALT AND CRYSTAL FORM OF A FAK INHIBITORSeptember 2021June 2025Allow4510NoNo
17448771HYDROXYPROPYL METHYL CELLULOSE PHTHALATE, METHOD FOR PRODUCING THE SAME, AND COMPOSITION FOR HOT-MELT EXTRUSIONSeptember 2021July 2025Allow4641NoNo
17442214SUSTAINED RELEASE COMPOSITION COMPRISING TAPENTADOL AND METHOD OF PREPARATION THEREOFSeptember 2021September 2025Abandon4701NoNo
17440075STABILIZED THIOKETONE FORMULATIONSSeptember 2021August 2025Abandon4701NoNo
17435863Orai Channel InhibitorsSeptember 2021June 2025Allow4511NoNo
17431422COMPOSITIONS AND METHODS FOR TREATMENT OF DEPRESSION AND OTHER DISORDERSAugust 2021July 2025Allow4720YesNo
174310076-OXO-1,6-DIHYDROPYRIDAZINE PRODRUG DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINEAugust 2021May 2025Abandon4501NoNo
17310623FATTY ACID COMPOSITION AND APPLICATION THEREOFAugust 2021September 2025Abandon5020NoNo
17428997DIHYDROOROTATE DEHYDROGENASE INHIBITORSAugust 2021March 2025Abandon4301NoNo
17428850PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED JAK INHIBITORSAugust 2021January 2025Allow4201YesNo
17428556Sclerostin Inhibitors That Promote Bone Morphogenetic Protein ExpressionAugust 2021March 2025Abandon4301NoNo
17427949METHODS AND COMPOUNDS FOR INHIBITION OF INACTIVATION OF VOLTAGE-GATED SODIUM CHANNELSAugust 2021October 2025Allow5011NoNo
17421832METHOD FOR TREATING AN ACUTE MYELOID LEUKEMIAJuly 2021January 2026Abandon5430NoNo
17422108DIHYDROPYRAZOLOPYRAZINONE DERIVATIVE HAVING MGAT2 INHIBITORY ACTIVITYJuly 2021July 2024Allow3600NoNo
17421867NEW FORMULATIONS CONTAINING LEUKOTRIENE RECEPTOR ANTAGONISTSJuly 2021December 2024Abandon4101NoNo
17415236TREATMENT OF MOVEMENT DISORDERSJune 2021November 2024Abandon4101NoNo
17296693Cosmetic Mask Comprising a Plant Paper and HumectantMay 2021June 2025Abandon4820NoNo
17326383CONTINUOUS PROCESS FOR MANUFACTURING ALKYL 7-AMINO-5-METHYL-[1,2,5]OXADIAZOLO[3,4-B]PYRIDINE-CARBOXYLATEMay 2021March 2024Allow3310NoNo
17294965COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITYMay 2021July 2025Abandon5011NoNo
17293155METHODS OF TREATING CANCERMay 2021September 2024Abandon4010NoNo
17293114PHARMACEUTICAL COMPOSITION FOR TREATING DIFFUSE-TYPE GASTRIC CANCERMay 2021March 2025Abandon4620NoNo
17293292MACROCYCLIC INHIBITORS OF DYRK1AMay 2021July 2024Allow3801NoNo
17290727PHOSPHATE COMPOUNDS FOR DETECTING NEUROLOGICAL DISORDERSApril 2021April 2024Allow3610NoNo
17244726COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF ANDROGEN-MEDIATED DISEASEApril 2021July 2025Abandon5021NoNo
17283948COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASEApril 2021July 2024Abandon3910NoNo
17283111TOPICAL COMPOSITIONSApril 2021December 2024Abandon4411YesNo
17280319COMPOUNDS THAT ENHANCE THE ACTION OF METFORMINMarch 2021March 2025Abandon4820NoNo
17280049SYNERGIC PHARMACEUTICAL COMBINATION OF A LEUKOTRIENE-RECEPTOR ANTAGONIST AND AN INVERSE AGONIST OF HISTAMINE HIMarch 2021July 2024Abandon4010NoNo
17173669Adelmidrol For Use In Diseases Characterized By Insufficient Agonism Of PPAR-GAMMA ReceptorFebruary 2021May 2025Abandon5140NoNo
17264638PREPARATION AND APPLICATION OF CLASS OF N-CONTAINING HETEROCYCLIC COMPOUNDS HAVING IMMUNOREGULATORY FUNCTIONJanuary 2021July 2024Abandon4101NoNo
17264411DIFFUSION ENHANCING COMPOUNDS AND THEIR USE WITH THROMBECTOMY AND EMBOLECTOMY AND OTHER VASCULAR DISEASE PROCEDURESJanuary 2021April 2024Abandon3810NoNo
17264478SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERSJanuary 2021December 2024Allow4731YesNo
17262682COMPOUNDS, DERIVATIVES, AND ANALOGS FOR CANCERJanuary 2021December 2023Allow3400NoNo
17155865TAAR Receptor Agonists for the Treatment of AlopeciaJanuary 2021April 2024Abandon3801NoNo
17262082NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAMEJanuary 2021June 2025Allow5321NoNo
17261129CHALCONES AND DERIVATIVES FOR USE IN MEDICAMENTS AND NUTRACEUTICALSJanuary 2021March 2024Abandon3810NoNo
17260388COMBINATION FOR TREATING CANCERJanuary 2021August 2025Allow5530YesNo
15733874Mitochondrial Conductance Inhibitors and Methods of Use ThereofNovember 2020August 2024Abandon4401NoNo
17055425INDOLINE-1-FORMAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOFNovember 2020April 2025Allow5321NoNo
17041653SUB-NANOMETER GOLD STICKER AND METHODS FOR PROTECTING AGAINST ENDOTOXIN-INDUCED SEPSIS THEREOFSeptember 2020August 2025Abandon5831YesNo
16980003USE OF CALORIC RESTRICTION MIMETICS FOR POTENTIATING CHEMO-IMMUNOTHERAPY FOR THE TREATMENT OF CANCERSSeptember 2020January 2025Abandon5221NoNo
16977485PROCESS AND INTERMIDIATES FOR THE PREPARATION OF CERTAIN MESOIONIC PESTICIDESSeptember 2020March 2025Allow5421YesNo

Appeals Overview

No appeal data available for this record. This may indicate that no appeals have been filed or decided for applications in this dataset.

Examiner RAMOS LEWIS, JOSMALEN MILAGROS - Prosecution Strategy Guide

Executive Summary

Examiner RAMOS LEWIS, JOSMALEN MILAGROS works in Art Unit 1621 and has examined 44 patent applications in our dataset. With an allowance rate of 36.4%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 45 months.

Allowance Patterns

Examiner RAMOS LEWIS, JOSMALEN MILAGROS's allowance rate of 36.4% places them in the 6% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by RAMOS LEWIS, JOSMALEN MILAGROS receive 1.25 office actions before reaching final disposition. This places the examiner in the 16% percentile for office actions issued. This examiner issues significantly fewer office actions than most examiners.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by RAMOS LEWIS, JOSMALEN MILAGROS is 45 months. This places the examiner in the 12% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +24.1% benefit to allowance rate for applications examined by RAMOS LEWIS, JOSMALEN MILAGROS. This interview benefit is in the 70% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 31.8% of applications are subsequently allowed. This success rate is in the 66% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 28.6% of cases where such amendments are filed. This entry rate is in the 40% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Petition Practice

When applicants file petitions regarding this examiner's actions, 28.6% are granted (fully or in part). This grant rate is in the 16% percentile among all examiners. Strategic Note: Petitions are rarely granted regarding this examiner's actions compared to other examiners. Ensure you have a strong procedural basis before filing a petition, as the Technology Center Director typically upholds this examiner's decisions.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 0% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 25.0% of allowed cases (in the 94% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.