USPTO Examiner CARCANAGUE DANIEL R - Art Unit 1621

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
19352234SUBSTITUTED HETEROCYCLES AND USES THEREOFOctober 2025December 2025Allow200NoNo
18755447AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCERJune 2024December 2025Allow1811NoNo
18657306DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGSMay 2024December 2025Allow1910YesNo
18630760MACROCYCLIC COMPOUNDS AND USES THEREOFApril 2024December 2025Allow2010NoNo
18605922COMPOUNDS AND COMPOSITIONS AND USES THEREOFMarch 2024August 2025Abandon1701NoNo
18421022PROCESS FOR THE PRODUCTION OF TETRAAMINOBIPHENOL MACROCYCLIC LIGANDS; AND NOVEL TETRAAMINOBIPHENOL MACROCYCLIC LIGANDSJanuary 2024August 2025Allow1800NoNo
18416455DERIVATIVES OF SUBSTITUTED MORPHOLINES AND USES THEREOFJanuary 2024July 2024Allow610NoNo
18401832PROCESS FOR THE PREPARATION OF A PDE4 INHIBITORJanuary 2024September 2025Allow2121NoNo
18537481PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USEDecember 2023July 2025Allow2000NoNo
18535218BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOFDecember 2023January 2026Allow2510YesNo
18534285MODULATORS OF RHO-ASSOCIATED PROTEIN KINASEDecember 2023July 2025Allow1910NoNo
18524322N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonistsNovember 2023March 2025Allow1610NoNo
18523516TRICYCLIC FUSED THIOPHENE DERIVATIVES AS JAK INHIBITORSNovember 2023January 2025Allow1400NoNo
18509658METHIONINE ADENOSYLTRANSFERASE 2a (MAT2A) INHIBITORS AND USES THEREOFNovember 2023February 2024Allow300NoNo
18505940BRUTON'S TYROSINE KINASE INHIBITORSNovember 2023July 2025Abandon2110NoNo
18503556COMPOUNDS AND METHODS FOR TREATING CANCERNovember 2023June 2025Allow1911NoNo
18384790COMPOUNDS AND THEIR USES AS MIF INHIBITORSOctober 2023July 2025Abandon2001NoNo
18484588TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USEOctober 2023April 2025Allow1810NoNo
18481173SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORSOctober 2023February 2024Allow410NoNo
18460821NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOFSeptember 2023November 2024Allow1400NoNo
18241636BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAMESeptember 2023June 2025Allow2110YesNo
18019452SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORSSeptember 2023April 2025Allow2611YesNo
18237435NOVEL PROCESS FOR PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORSAugust 2023June 2025Abandon2110NoNo
18236001PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVESAugust 2023May 2025Abandon2110NoNo
18355792INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASEJuly 2023September 2024Allow1400YesNo
18222679PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINEJuly 2023February 2025Allow1910NoNo
18334672THERAPEUTIC DENDRIMERSJune 2023March 2025Abandon2110NoNo
18329092METHOD OF FIXATING CARBON DIOXIDE TO SUBSTITUTED OXAZOLIDINONESJune 2023January 2026Allow3100NoNo
18039386MERGED SCAFFOLD TAF1 INHIBITORSMay 2023January 2026Allow3100NoNo
18322844Chemical CompoundsMay 2023August 2024Allow1400NoNo
18144641BICYCLIC COMPOUNDS AS KINASE MODULATORS, METHODS AND USES THEREOFMay 2023November 2024Allow1810NoNo
18144065COMBINATIONS OF 15-PGDH INHIBITORS WITH CORTICOSTEROIDS AND/OR TNF INHIBITORS AND USES THEREOFMay 2023September 2025Abandon2811NoNo
18136517Charged Ion Channel Blockers and Methods for UseApril 2023February 2025Allow2210YesNo
18302259Aminothiazole Compounds as Inhibitors of CTPS1April 2023August 2025Allow2711NoNo
18302557PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSESApril 2023November 2024Allow1910NoNo
18134564PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDEApril 2023January 2025Allow2111NoNo
18300234COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERSApril 2023January 2025Allow2111YesNo
18248065MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORApril 2023December 2025Allow3300YesNo
182479396-METHOXY-3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUNDSApril 2023August 2025Allow2800YesNo
18295394CDK Inhibitors And Their Use As PharmaceuticalsApril 2023July 2025Allow2821NoNo
18168322INHIBITORS OF PARGFebruary 2023October 2024Allow2011YesNo
18152987PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICSJanuary 2023October 2024Allow2110NoNo
181486724-(METHYLAMINOPHENOXY)PYRDIN-3-YL-BENZAMIDE DERIVATIVES FOR TREATING CANCERDecember 2022November 2024Abandon2210NoNo
18147499DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGSDecember 2022February 2024Allow1310NoNo
18146513ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND METHODSDecember 2022October 2024Abandon2210NoNo
18087774TREATING SICKLE CELL DISEASE WITH A PYRUVATE KINASE R ACTIVATING COMPOUNDDecember 2022March 2024Allow1400NoNo
18011460OXOPYRIDAZINYL-PHENYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOFDecember 2022December 2025Allow3610NoNo
18011459FUSED-HETEROCYCLYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS AND USE THEREOFDecember 2022December 2025Allow3510YesNo
18066389THERMALLY REACTIVE IMIDAZOLE-BASED LATENT CURING AGENT AND METHOD OF PREPARING THE SAMEDecember 2022February 2025Abandon2621NoNo
180623562-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTSDecember 2022June 2024Allow1810NoNo
18075557HETEROCYCLIC ANTIVIRAL AGENTSDecember 2022July 2024Allow1910NoNo
17989393Compounds for the Treatment of Kinase-Dependent DisordersNovember 2022August 2024Abandon2110NoNo
18055874CHROMANE AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONSNovember 2022June 2023Allow700NoNo
17987208CRYSTALLINE N-METHYL TRYPTAMINE DERIVATIVESNovember 2022December 2025Abandon3701NoNo
17986325RADICAL COMPOUNDS AND METHODS OF USING THEREOFNovember 2022January 2024Allow1400YesNo
18054272OLAPARIB HYDROXYBENZOIC ACID COCRYSTALS AND THEIR PHARMACEUTICAL USENovember 2022March 2024Allow1610NoNo
17983484ALKYNE-CONTAINING ANTIVIRAL AGENTSNovember 2022August 2023Allow900NoNo
18051471SOLID FORMS OF FXR AGONISTSOctober 2022June 2024Allow1901YesNo
17962273Substituted Imidazo[4,5-c]pyridine Compounds and Compositions ThereofOctober 2022July 2024Abandon2210NoNo
17960586CONJOINT THERAPIES FOR IMMUNOMODULATIONOctober 2022April 2024Allow1810NoNo
17951640PYRIDINE DERIVATIVES AND THEIR USE AS SODIUM CHANNEL ACTIVATORSSeptember 2022March 2024Allow1810NoNo
17942928USE OF NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS FOR IMMUNOTHERAPY IN MELANOMA PATIENTSSeptember 2022May 2024Allow2010NoNo
17940617SUBSTITUTED MACROCYCLIC INDOLE DERIVATIVESSeptember 2022October 2023Allow1300YesNo
17903735N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonistsSeptember 2022September 2023Allow2010NoNo
17896626MODULATORS OF RHO-ASSOCIATED PROTEIN KINASEAugust 2022September 2023Allow1300YesNo
17820374SUBSTITUTED ENEOXINDOLES AND USES THEREOFAugust 2022February 2024Allow1810NoNo
17820271Aryl Sulfonyl (Hydroxy) Piperidines as CCR6 InhibitorsAugust 2022October 2023Allow1410YesNo
17879600METHODS OF MANUFACTURING BENZOQUINOLINE COMPOUNDSAugust 2022April 2024Allow2110YesNo
17815391PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USEJuly 2022September 2023Allow1400YesNo
17813382P38ALPHA MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORSJuly 2022December 2023Allow1710NoNo
17607115TROLOX-PEPTIDE CONJUGATE AND USE THEREOFJuly 2022November 2025Allow4810NoNo
17844772Compounds and Methods for Treatment of Visceral PainJune 2022October 2024Allow2811YesNo
17807464TRICYCLIC PYRIDONES AND PYRIMIDONESJune 2022December 2025Abandon4210NoNo
17783810BICYCLIC HETEROCYCLE COMPOUNDS METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSESJune 2022August 2025Allow3800NoNo
17834847QUINOLINE DERIVED SMALL MOLECULE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOFJune 2022April 2024Allow2220YesNo
17780903SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATIONMay 2022August 2025Allow3901YesNo
17664305TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USEMay 2022July 2023Allow1400NoNo
17743214BRUTON'S TYROSINE KINASE INHIBITORSMay 2022January 2024Abandon2010NoNo
17743016Blue Phosphorescent Material, Production Method Thereof, and Photophysical Properties ThereofMay 2022November 2025Allow4220NoNo
17738630PROCESS FOR THE PREPARATION OF A PDE4 INHIBITORMay 2022October 2023Allow1710NoNo
17774638METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ISCHEMIA REPERFUSION INJURY AND INFECTIONMay 2022November 2025Allow4321NoNo
17734875COMBINATION THERAPY OF AXL INHIBITOR AND EGFR TYROSINE KINASE INHIBITORMay 2022August 2023Allow1510NoNo
17773490MODIFIED ZEOLITE CATALYST COMPOSITIONS AND METHODS OF USEApril 2022November 2025Allow4311NoNo
17720007Process For The Preparation Of Highly Pure Salcaprozic Acid And Pharmaceutically Acceptable Salts ThereofApril 2022January 2023Allow900NoNo
17708296PROCESS FOR PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORSMarch 2022May 2023Allow1400NoNo
17699793Methods, Agents, and Compositions for the Treatment of Acute Myeloid LeukemiaMarch 2022January 2024Allow2220NoNo
17698592DERIVATIVES OF SUBSTITUTED MORPHOLINES AND USES THEREOFMarch 2022October 2023Allow1910NoNo
17688822INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOFMarch 2022October 2023Allow2010NoNo
17676942MACROCYCLIC COMPOUNDS AND USES THEREOFFebruary 2022January 2024Allow2220NoNo
17670469THERAPEUTIC INHIBITION AFFINITY OF COPPER (II) COMPLEX AND THEIR DIAZENYL PYRIDINONE HETEROCYCLIC LIGANDS AGAINST SARS-COV2February 2022July 2023Allow1710NoNo
17650732HPK1 ANTAGONISTS AND USES THEREOFFebruary 2022November 2024Allow3350YesNo
17650387BAICALEIN ANALOGS FOR USE IN NEUROPROTECTION AND REGULATION OF IMMUNE REACTIVITYFebruary 2022September 2023Allow1910NoNo
17585145SULFATE SALT OF THE FREE BASE OF N-[5-(AMINOSULFONYL)-4-METHYL-1,3-THIAZOL-2-YL]-N-METHYL-2-[4-(2-PYRIDINYL)-PHENYL]-ACETAMIDE, PHARMACEUTICAL FORMULATIONS, METHODS OF MANUFACTURE AND USES THEREOFJanuary 2022April 2024Allow2720NoNo
17559546PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOFDecember 2021February 2025Allow3800YesNo
17596388OXO-PYRIDINE FUSION RING DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAMEDecember 2021October 2025Abandon4601NoNo
175324137-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAMENovember 2021October 2023Allow2310NoNo
17532036ANTI-PARASITIC COMPOUNDS AND USES THEREOFNovember 2021April 2024Allow2911NoNo
17525778IRE1ALPHA INHIBITORS AND USES THEREOFNovember 2021September 2023Allow2210NoNo
17523652PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOFNovember 2021April 2023Allow1800YesNo
17519013INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOFNovember 2021September 2023Allow2310NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner CARCANAGUE, DANIEL R.

Strategic Value of Filing an Appeal

Total Appeal Filings
1
Allowed After Appeal Filing
1
(100.0%)
Not Allowed After Appeal Filing
0
(0.0%)
Filing Benefit Percentile
95.6%
Higher than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 100.0% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the top 25% across the USPTO, indicating that filing appeals is particularly effective here. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Strategic Recommendations

Filing a Notice of Appeal is strategically valuable. The act of filing often prompts favorable reconsideration during the mandatory appeal conference.

Examiner CARCANAGUE, DANIEL R - Prosecution Strategy Guide

Executive Summary

Examiner CARCANAGUE, DANIEL R works in Art Unit 1621 and has examined 179 patent applications in our dataset. With an allowance rate of 91.1%, this examiner allows applications at a higher rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 24 months.

Allowance Patterns

Examiner CARCANAGUE, DANIEL R's allowance rate of 91.1% places them in the 75% percentile among all USPTO examiners. This examiner is more likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by CARCANAGUE, DANIEL R receive 1.31 office actions before reaching final disposition. This places the examiner in the 18% percentile for office actions issued. This examiner issues significantly fewer office actions than most examiners.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by CARCANAGUE, DANIEL R is 24 months. This places the examiner in the 81% percentile for prosecution speed. Applications move through prosecution relatively quickly with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +11.1% benefit to allowance rate for applications examined by CARCANAGUE, DANIEL R. This interview benefit is in the 45% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 29.8% of applications are subsequently allowed. This success rate is in the 57% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 86.5% of cases where such amendments are filed. This entry rate is in the 97% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 86% percentile among all examiners. Of these withdrawals, 100.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 66.7% are granted (fully or in part). This grant rate is in the 71% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.0% of allowed cases (in the 0% percentile). This examiner rarely makes examiner's amendments compared to other examiners. You should expect to make all necessary claim amendments yourself through formal amendment practice.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.2% of allowed cases (in the 63% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.