USPTO Examiner SHOMER ISAAC - Art Unit 1612

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18957404MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMESNovember 2024April 2025Allow510YesNo
18864569TRIPTOLIDE LIGNOCERATE, LIPOSOME THEREOF AND PREPARATION METHOD THEREFORNovember 2024January 2026Allow1421NoNo
18922818MEDICAL MATERIALOctober 2024July 2025Allow911YesNo
18908438ARTESUNATE POWDERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF MANUFACTUREOctober 2024May 2025Allow711YesNo
18848678BIOACTIVE GRANULAR HYDROGEL SCAFFOLDS AND USE THEREOFSeptember 2024April 2025Allow720YesNo
18825766LARGE-SCALE MANUFACTURING METHODS FOR AMINOGLYCOSIDESSeptember 2024September 2025Allow1321YesNo
18833679ANTIBODY-BOUND LIPID NANOPARTICLE COMPRISING ANTIBODY BOUND TO MEMBRANE SCAFFOLD PROTEINAugust 2024July 2025Allow1110YesNo
18762795MANGANESE-DOPED HOLLOW MESOPOROUS SILICA NANOPARTICLES LOADED WITH CURCUMINJuly 2024November 2024Allow510NoNo
18761863MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMESJuly 2024October 2024Allow311YesNo
18761882MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMESJuly 2024November 2024Allow511YesNo
18676591Methods for Treating Metastatic Pancreatic Cancer Using Combination Therapies Comprising Liposomal Irinotecan and OxaliplatinMay 2024April 2025Abandon1110NoNo
18651154METHODS FOR DECREASING INJURIES ASSOCIATED WITH INTRAOPERATIVE HYPOTENSIONApril 2024November 2025Allow1820YesYes
18636721Atomic Scale Topical Composition with Enhanced Interstitial Cellular Uptake for Increased Moisturizing, Fluidity, Antioxidant and Radiation Protection, Antimicrobial Cleansing and Therapeutics for Optimal Dermal Integrity and Homeostasis.April 2024November 2024Allow721YesNo
18613609Methods For Treating Pancreatic Cancer Using Combination Therapies Comprising Liposomal IrinotecanMarch 2024November 2025Abandon2040YesNo
18607029CANCER THERAPY COMPOSITIONS AND USES THEREOFMarch 2024August 2025Allow1731NoNo
18583453GREEN SYNTHESIS OF SILVER NANOPARTICLES ENCAPSULATED IN A NANOSTRUCTURED LIPID CARRIERFebruary 2024September 2024Allow711YesNo
18443850ARTESUNATE POWDERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF MANUFACTUREFebruary 2024September 2024Allow711YesNo
18436704COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREOF AND USE THEREOFFebruary 2024April 2025Allow1421YesNo
18432899BLOCK COPOLYMERS AND USES THEREOFFebruary 2024May 2025Abandon1510NoNo
18544197COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSEDecember 2023April 2025Abandon1601NoNo
18503327LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINESNovember 2023October 2024Allow1121YesNo
18289200NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOFNovember 2023October 2024Allow1110YesNo
18377679PARTICLE AND PHARMACEUTICAL COMPOSITION COMPRISING AN INSOLUBLE CAMPTOTHECIN COMPOUND WITH DOUBLE CORESHELL STRUCTURE AND METHOD FOR MANUFACTURING THE SAMEOctober 2023January 2026Abandon2710NoNo
18375788NANO-PARTICLES THAT CONTAIN SYNTHETIC VARIANTS OF GM3 GANGLIOSIDE AS ADJUVANTS IN VACCINESOctober 2023December 2024Allow1510NoNo
18458767LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINESAugust 2023January 2026Abandon2921NoNo
18456371Synthetic Nanostructures Including Nucleic Acids and/or Other EntitiesAugust 2023August 2025Abandon2450NoNo
18547664BISPECIFIC NANOPARTICLE SYSTEMS FOR TARGETING CANCER CELLSAugust 2023January 2026Allow2911YesNo
18235980HYBRID BIOLOGICAL MEMBRANES, METHODS OF MAKING AND USES THEREOFAugust 2023October 2025Abandon2630NoNo
18232877Atomic Scale Topical Composition with Enhanced Interstitial Cellular Uptake for Increased Moisturizing, Fluidity, Antioxidant and Radiation Protection, Antimicrobial Cleansing and Therapeutics for Optimal Dermal Integrity and HomeostasisAugust 2023December 2023Allow410YesNo
18365187COMPOSITIONS AND METHODS FOR ORGAN SPECIFIC DELIVERY OF NUCLEIC ACIDSAugust 2023November 2025Abandon2810NoNo
18363531BHB LIPOSOMES AND PREPARATION METHODS THEREOFAugust 2023March 2026Allow3211YesNo
18263649TREATMENT FOR MALIGNANT PLEURAL EFFUSION IN HUMANSJuly 2023February 2026Abandon3110NoNo
18225749PEGYLATED LIPOSOMES FOR DELIVERY OF IMMUNOGEN-ENCODING RNAJuly 2023March 2026Abandon3210NoNo
18225585Methods of Treating Inflammatory Disorders and Global Inflammation with Compositions Comprising Phospholipid Nanoparticle Encapsulations of Anti-Inflammatory NutraceuticalsJuly 2023November 2025Abandon2801NoNo
18222839AMINO ALCOHOL IONIZABLE LIPIDSJuly 2023March 2026Abandon3201NoNo
18221262NONCOMPETITIVE RECEPTOR-TARGETED VACCINE DELIVERY TO PLASMACYTOID DENDRITIC CELLSJuly 2023November 2025Allow2810NoNo
18343349Liposomes Containing Phosphorylated Tau Peptides for Inducing Sustained Immune ResponsesJune 2023March 2025Abandon2130YesNo
18259346REDUCED GRAPHENE OXIDE (rGO) BASED DRUG CARRIER SYSTEMSJune 2023November 2025Allow2910NoNo
18214021Method of Synthesis of a Nanocomposite including Silymarin-loaded Collagen NanoparticlesJune 2023October 2023Allow410YesNo
18214060FREEZE-DRIED PRODUCT AND GAS-FILLED MICROVESICLES SUSPENSIONJune 2023October 2025Allow2820NoNo
18338485METHODS OF MAKING LIPID NANOPARTICLESJune 2023February 2025Allow2020NoNo
18329969Semisolid Oral Dispersions Comprising Active AgentsJune 2023July 2025Allow2520NoNo
18038978COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING LIPID NANOPARTICLESMay 2023January 2026Abandon3210NoNo
18038979LIPID NANOPARTICLES COMPRISING MANNOSE OR USES THEREOFMay 2023February 2026Abandon3301NoNo
18196235LIPID NANOPARTICLESMay 2023January 2025Abandon2110NoNo
18297255COMPOUNDS AND COMPOSITIONS FOR DRUG DELIVERYApril 2023February 2025Abandon2241YesNo
18193689METHOD FOR FORMING A NANOMEDICINAL COMPOSITIONMarch 2023January 2025Allow2110NoNo
18193692METHOD FOR TREATING BLASTOCYSTIS INFECTIONMarch 2023August 2024Allow1610YesNo
18191517Structure-Function Relationships in the Development of Immunotherapeutic AgentsMarch 2023June 2025Abandon2701NoNo
18190219DELIVERY SYSTEM FOR USE IN MEDICINEMarch 2023August 2025Abandon2911NoNo
18120298NANOFORMULATION OF SPRIOOXINDOLE AND METHODS FOR TREATING HEPATOCELLULAR CARCINOMAMarch 2023November 2023Allow810YesNo
18181163LIPOSOMAL COMPOSITION FOR USE IN A METHOD OF TREATING PARKINSON'S DISEASEMarch 2023January 2026Allow3520NoNo
18114434PEGYLATED LIPOSOMES FOR DELIVERY OF IMMUNOGEN-ENCODING RNAFebruary 2023December 2024Abandon2110NoNo
18021613AMPHIPHILIC MATERIAL AND APPLICATION THEREOF IN PREPARATION FOR LIPOSOMEFebruary 2023March 2024Allow1320NoNo
18107353SUSTAINED RELEASE PARTICLE FORMULATIONSFebruary 2023June 2025Allow2911YesNo
18104620LIPID-BASED NANOPARTICLES WITH ENHANCED STABILITYFebruary 2023October 2025Abandon3311NoNo
18100201Semisolid Oral Dispersions Comprising Active AgentsJanuary 2023March 2025Allow2611YesNo
18150528LIPID NANOPARTICLESJanuary 2023January 2026Allow3611YesNo
18150399ORAL COMPOSITIONS AND THE PREPARATION METHODS THEREOFJanuary 2023January 2025Allow2410NoNo
18083458NANOPARTICLES ENCAPSULATING SOLUBLE BIOLOGICS, THERAPEUTICS, AND IMAGING AGENTSDecember 2022December 2025Allow3621YesNo
17988857Liposomes Useful for Drug DeliveryNovember 2022February 2025Abandon2710NoNo
18054131LEVERAGING LIPID-PROTEIN INTERACTIONS TO ENGINEER SPATIAL ORGANIZATION IN CELL-FREE SYSTEMSNovember 2022November 2025Allow3711NoNo
17959983PLANT MEDIUM INCLUDING AN OXYGEN-ENABLED COMPOSITIONOctober 2022November 2024Abandon2510NoNo
17952593EXOSOME SYSTEMS, PRODUCTS AND METHODSSeptember 2022January 2025Abandon2810NoNo
17941669COMPOSITIONS AND SYSTEMS COMPRISING TRANSFECTION-COMPETENT VESICLES FREE OF ORGANIC-SOLVENTS AND DETERGENTS AND METHODS RELATED THERETOSeptember 2022August 2023Allow1121YesNo
17899933Stabilizing Camptothecin Pharmaceutical CompositionsAugust 2022October 2024Abandon2610NoNo
17886590COMPOSITIONS FOR CONTROLLED RELEASE OF ACTIVE INGREDIENTS AND METHODS OF MAKING SAMEAugust 2022August 2025Abandon3611NoNo
17873404LIPID COMPOUND AS WELL AS LIPID VECTOR, NUCLEIC ACID LIPID NANOPARTICLE COMPOSITION, AND PHARMACEUTICAL PREPARATION COMPRISING THE SAMEJuly 2022June 2023Allow1111YesNo
17872974FREEZE-DRIED PRODUCT AND GAS-FILLED MICROVESICLES SUSPENSIONJuly 2022March 2023Allow810NoNo
17871768FUSOGENIC LIPOSOME-COATED POROUS SILICON NANOPARTICLESJuly 2022December 2025Allow4120NoNo
17813001LIPOSOMAL FORMULATIONS OF BCL INHIBITORSJuly 2022March 2025Allow3250YesYes
17812946SUSTAINED DRUG DELIVERY IMPLANTJuly 2022October 2024Abandon2710NoNo
17864524ANTIMICROBIAL COATING MATERIAL FOR SURFACE COATINGJuly 2022February 2026Allow4321YesNo
17792259NUCLEIC ACID LOADED RED BLOOD CELL EXTRACELLULAR VESICLESJuly 2022February 2026Abandon4311NoNo
17810064LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINESJune 2022May 2023Allow1120YesNo
17810055LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINESJune 2022December 2023Abandon1720YesYes
17808412BIOERODIBLE CROSS-LINKED HYDROGEL IMPLANTS AND RELATED METHODS OF USEJune 2022July 2024Allow2510NoNo
17847808OXYGEN GAS SUSTAINED RELEASED NANO-EMULSION COMPOSITION AND METHOD FOR PRODUCING THE SAMEJune 2022December 2023Allow1821YesNo
17842876METAL ORGANIC FRAMEWORK/POROUS SILICATE AND/OR ALUMINOSILICATE NANOCARRIER FOR BLASTOCYSTOSIS TREATMENTJune 2022September 2023Allow1521YesNo
17840700CAPE-LOADED TARGETED MICROVESICULAR CANCER DRUG AND METHOD FOR DEVELOPING THE SAMEJune 2022August 2024Allow2620YesNo
17835634METHOD FOR PREVENTING OR TREATING UROLOGICAL CHRONIC PELVIC PAIN SYNDROMEJune 2022October 2025Allow4031YesNo
17831962CABAZITAXEL WEAKLY- ALKALINE DERIVATIVE AND FORMULATION THEREOFJune 2022September 2025Abandon3910NoNo
17830615PROTEIN-LOADED PLGA NANOSPHERESJune 2022August 2024Allow2750YesNo
17831258PROCESS FOR FORMULATING AN ANIONIC AGENTJune 2022December 2025Abandon4201NoNo
17829960DELIVERY OF AGENTS USING METASTABLE LIPOSOMESJune 2022September 2024Allow2711YesNo
17746249TREATMENT OF HIP PAIN WITH SUSTAINED-RELEASE LIPOSOMAL ANESTHETIC COMPOSITIONSMay 2022September 2023Allow1631YesNo
17740426Core Shell Silica Particles and Uses Thereof As an Anti-Bacterial AgentMay 2022February 2025Allow3320NoNo
17775422CAROTENOID COMPOSITIONS AND USES THEREOFMay 2022October 2025Abandon4101NoNo
17727993METHODS OF IMPROVING THE SOLUBILITY AND BIOAVAILABILITY OF THERAPEUTIC AGENTSApril 2022December 2024Allow3101YesNo
17713679EXOSOME SYSTEMS, PRODUCTS AND METHODSApril 2022April 2024Abandon2441NoNo
17754327Process for preparing nanoparticles in the form of a powder comprising a bio-resorbable polyesterMarch 2022February 2024Allow2240YesNo
17703824SYNTHETIC NANOSTRUCTURES INCLUDING NUCLEIC ACIDS AND/OR OTHER ENTITIESMarch 2022January 2026Abandon4611NoNo
17761480PROCESS FOR PRODUCING A PHARMACEUTICAL FORMULATION COMPRISING ACTIVE SUBSTANCE, POLYMER AND SURFACTANTMarch 2022October 2025Allow4311NoNo
17695999COMPOSITIONS FOR CONTROLLED RELEASE OF ACTIVE INGREDIENTS AND METHODS OF MAKING SAMEMarch 2022November 2024Abandon3201NoNo
17696225POLYMER MEDICAMENT FOR TREATING HYPERKALEMIA AND PREPARATION METHOD THEREOFMarch 2022November 2025Abandon4421YesNo
17684805TREATMENT OF HIP PAIN WITH SUSTAINED-RELEASE LIPOSOMAL ANESTHETIC COMPOSITIONSMarch 2022September 2023Allow1931YesNo
17589554ANTIFUNGAL NANOPARTICLES FOR TARGETED TREATMENT OF FUNGAL INFECTIONSJanuary 2022July 2024Abandon2901NoNo
17581482NANOCOMPLEXES OF POLYANION-MODIFIED PROTEINSJanuary 2022March 2025Abandon3821NoNo
17579832ACOUSTIC DRIVEN DRUG DELIVERY SYSTEMSJanuary 2022September 2024Allow3240YesNo
17628559NANOCOMPOSITE PARTICLE AND USES THEREOFJanuary 2022October 2025Allow4501NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner SHOMER, ISAAC.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
18
Examiner Affirmed
12
(66.7%)
Examiner Reversed
6
(33.3%)
Reversal Percentile
49.0%
Lower than average

What This Means

With a 33.3% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
108
Allowed After Appeal Filing
26
(24.1%)
Not Allowed After Appeal Filing
82
(75.9%)
Filing Benefit Percentile
32.8%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 24.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner SHOMER, ISAAC - Prosecution Strategy Guide

Executive Summary

Examiner SHOMER, ISAAC works in Art Unit 1612 and has examined 1,156 patent applications in our dataset. With an allowance rate of 61.6%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 31 months.

Allowance Patterns

Examiner SHOMER, ISAAC's allowance rate of 61.6% places them in the 22% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by SHOMER, ISAAC receive 2.50 office actions before reaching final disposition. This places the examiner in the 73% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by SHOMER, ISAAC is 31 months. This places the examiner in the 53% percentile for prosecution speed. Prosecution timelines are slightly faster than average with this examiner.

Interview Effectiveness

Conducting an examiner interview provides a +34.4% benefit to allowance rate for applications examined by SHOMER, ISAAC. This interview benefit is in the 82% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 25.2% of applications are subsequently allowed. This success rate is in the 39% percentile among all examiners. Strategic Insight: RCEs show below-average effectiveness with this examiner. Carefully evaluate whether an RCE or continuation is the better strategy.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 30.2% of cases where such amendments are filed. This entry rate is in the 44% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 64.3% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 52% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences show above-average effectiveness with this examiner. If you have strong arguments, a PAC request may result in favorable reconsideration.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 75.0% of appeals filed. This is in the 63% percentile among all examiners. Of these withdrawals, 64.8% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 72.5% are granted (fully or in part). This grant rate is in the 79% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 0.8% of allowed cases (in the 64% percentile). This examiner makes examiner's amendments more often than average to place applications in condition for allowance (MPEP § 1302.04).

Quayle Actions: This examiner issues Ex Parte Quayle actions in 1.7% of allowed cases (in the 66% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.