USPTO Examiner WEN SHARON X - Art Unit 1641

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18988307HUMANIZED ANTIBODIES AGAINST IRHOM2December 2024March 2025Allow300YesNo
18962263ANTI-S100A4 HUMANIZED ANTIBODIES, USES AND METHODSNovember 2024April 2025Allow411NoNo
18895539HEPARANASE-NEUTRALIZING A54 MONOCLONAL ANTIBODYSeptember 2024June 2025Allow810YesNo
18597624REGIMENS AND METHODS OF TREATING MULTIPLE SCLEROSIS USING OFATUMUMABMarch 2024February 2025Allow1111YesNo
18515714ANTIBODIES THAT BIND TO C1S AND USES THEREOFNovember 2023April 2024Allow501YesNo
18486137ANTIBODIES TO 25-HYDROXYVITAMIN D2 AND D3 FOR DETECTING TOTAL 25-HYDROXYVITAMIN DOctober 2023May 2025Allow1910NoNo
18481529COMPOSITIONS AND METHODS FOR TREATMENT OF CHRONIC LUNG DISEASESOctober 2023August 2024Allow1021YesNo
18356928Anti-Dectin-2 Antibodies and Methods of UsingJuly 2023February 2025Allow1900NoNo
18329172ANTI-TMPRSS6 ANTIBODIES AND USES THEREOFJune 2023September 2023Allow300YesNo
18312339ANTIGEN BINDING RECEPTORS SPECIFIC FOR MUTATED Fc DOMAINSMay 2023December 2024Allow2000NoNo
18302645POLYPEPTIDE USEFUL IN ADOPTIVE CELL THERAPYApril 2023November 2024Abandon1900NoNo
18300307METHOD OF TREATING RHEUMATOID ARTHRITIS USING ANTIBODIES TO OXIDIZED PHOSPHOLIPIDSApril 2023September 2024Allow1800NoNo
18187928Antibody Immune Cell Inhibitor Fusion ProteinsMarch 2023June 2025Abandon2701NoNo
18122948ANTIBODY BINDING TO A LINKER PEPTIDEMarch 2023June 2024Allow1500NoNo
18172059COMPOSITIONS AND METHODS FOR CAPTURING EXOSOMESFebruary 2023December 2024Allow2210YesNo
18159728METHODS OF DETERMINING THE FUNCTION OF POLYUBIQUITIN USING ANTI-POLYUBIQUITIN ANTIBODIESJanuary 2023September 2024Allow2000YesNo
18055992METHODS FOR MODULATING INTESTINE CELLS OR TISSUE FUNCTIONNovember 2022April 2025Abandon2931YesNo
18054080COMPOSITIONS AND METHODS FOR ENHANCING DONOR OLIGONUCLEOTIDE-BASED GENE EDITINGNovember 2022November 2024Abandon2421NoNo
17976613COMPOSITIONS FOR IMPROVING KIDNEY FUNCTION IN PATIENTS WITH HEPATORENAL SYNDROMEOctober 2022May 2025Abandon3040YesYes
17996601ANTIBODY CAPABLE OF BINDING SPECIFICALLY TO 5' TO 3' EXONUCLEASE ACTIVE DOMAIN OF DNA POLYMERASEOctober 2022December 2023Allow1411YesNo
18045313COMPOSITIONS AND METHODS OF TREATING LUPUS NEPHRITISOctober 2022February 2025Abandon2801NoNo
17916008ANTI-TMPRSS6 ANTIBODIES AND USES THEREOFSeptember 2022September 2024Allow2401YesNo
17887952ANTI-CERAMIDE ANTIBODIESAugust 2022September 2024Abandon2510NoNo
17854808METHODS AND USES FOR PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 (PCSK9) INHIBITORSJune 2022December 2024Abandon2910NoNo
17836862ANTIGEN BINDING MOLECULES SPECIFIC FOR AN ANTI-CD19 SCFVJune 2022September 2024Allow2711NoNo
17743177ANTIBODIES SPECIFIC FOR HUMAN ALPHA-SYNUCLEIN FOR TREATING ALPHA-SYNUCLEINOPATHIESMay 2022March 2025Allow3411YesNo
17660317DOSEApril 2022January 2025Abandon3331NoYes
17666252METHODS OF TREATING SKIN DISORDERSFebruary 2022September 2024Abandon3221NoNo
17578014CD38 ANTIBODYJanuary 2022April 2024Allow2710NoNo
17537786METHODS FOR TREATING GI SYNDROME AND GRAFT VERSUS HOST DISEASENovember 2021June 2024Allow3110NoNo
17531011ANTI-CD20 ANTIBODYNovember 2021March 2024Allow2811YesNo
17519063DOSING REGIMEN OF COMBINATION OF ANTI-CD20 AND ANTI-BLYS ANTIBODIESNovember 2021April 2024Allow2920NoNo
17515001Modulation of Proprotein Convertase Subtilisin/Kexin 9 Expression (PCSK9) with HSP 27 and/or HSP25October 2021March 2024Allow2920NoNo
17504921METHODS FOR REDUCING CARDIOVASCULAR RISKOctober 2021September 2024Abandon3511NoNo
17495559REGIMENS AND METHODS OF TREATING MULTIPLE SCLEROSIS USING OFATUMUMABOctober 2021February 2024Abandon2810NoNo
17493896PHARMACEUTICAL COMPOSITIONS AND METHODS TARGETING WNT PATHWAY PROTEINSOctober 2021December 2023Allow2710NoNo
17484794METHOD OF DETECTING TIM-3 USING ANTIBODY MOLECULES TO TIM-3September 2021June 2024Abandon3311NoNo
17460883ANTI-PSGL-1 ANTIBODIES AND USES THEREOFAugust 2021December 2023Allow2720NoNo
17370446METHODS OF TREATING ANAEMIAJuly 2021December 2023Abandon2910NoNo
17293134POLYPEPTIDE CONJUGATESMay 2021November 2024Abandon4301NoNo
17241628ANTIBODIES SPECIFICALLY BINDING TO MASP-3 FOR THE TREATMENT OF VARIOUS DISEASES AND DISORDERSApril 2021September 2023Allow2911NoNo
17221515ALIMENTARY AND SYSTEMIC ANTIVIRAL THERAPEUTICSApril 2021October 2023Abandon3101NoNo
17211619ANTI-CD20 GLYCOANTIBODIES AND USES THEREOFMarch 2021September 2023Allow3041YesYes
17203671METHOD FOR TREATING MULTIPLE SCLEROSISMarch 2021March 2024Abandon3611NoNo
17270827SUICIDE MODULE COMPOSITIONS AND METHODSFebruary 2021August 2024Allow4211NoNo
17127202MEDICAMENT COMPRISING ANTI-PHOSPHOLIPASE D4 ANTIBODYDecember 2020November 2023Abandon3511NoNo
17253824METHOD FOR SEPARATING ANTIBODY, AND METHOD FOR TESTING ON DISEASEDecember 2020May 2025Allow5321YesNo
17101780Reducing Immune Tolerance Induced by PD-L1November 2020November 2023Allow3511YesNo
17091375ANTIBODIES TO CD40November 2020October 2024Abandon4731YesNo
17087914ANTIBODIES TO 25-HYDROXYVITAMIN D2 AND D3November 2020May 2023Allow3010YesNo
17030627ANTI-CXCL13 ANTIBODIES AND METHODS OF USING THE SAMESeptember 2020January 2024Allow4011NoNo
17015212DKK1 ANTIBODIES AND METHODS OF USESeptember 2020June 2023Abandon3321NoNo
17010354PLASMA KALLIKREIN BINDING PROTEINS AND USES THEREOF IN TREATING HEREDITARY ANGIOEDEMASeptember 2020April 2025Allow5531NoNo
16991269METHODS FOR REDUCING OR ELIMINATING THE NEED FOR LIPOPROTEIN APHERESIS IN PATIENTS WITH HYPERLIPIDEMIA BY ADMINISTERING ALIROCUMABAugust 2020October 2023Allow3811NoNo
16966513NUCLEIC ACID MONOCLONAL ANTIBODIES TARGETING PCSK9 AND METHODS OF USEJuly 2020May 2024Allow4631NoNo
16958945Methods for Measuring RenalaseJune 2020October 2024Allow5121YesNo
16911954ANTI-COMPLEMENT FACTOR C1Q FAB FRAGMENTS AND USES THEREOFJune 2020January 2024Allow4321YesNo
16955391BIOMARKERS OF METHOTREXATE-INDUCED IMMUNE TOLERANCEJune 2020September 2024Allow5112YesNo
16772262BCMA SPECIFIC VCAR COMPOSITIONS AND METHODS FOR USEJune 2020May 2024Allow4721YesNo
16888989TARGETING B CELL ACTIVATING FACTOR RECEPTOR (BAFF-R) USING LIGAND-BASED CHIMERIC ANTIGEN RECEPTOR (CAR)-T CELLSJune 2020November 2023Allow4121YesNo
16887460METHODS OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 IN COMBINATION WITH CDK4/6 INHIBITORS FOR THE TREATMENT OF BREAST CANCERMay 2020May 2024Allow4821YesNo
16646240Pharmaceutical Composition Comprising Antibody Binding Specifically to Lysyl-Trna Synthetase N-Terminus as Effective Ingredient for Preventing or Treating Immune Cell Migration-Related DiseaseMay 2020December 2023Allow4521YesNo
16763134ANTI-C1S ANTIBODIES AND METHODS OF USEMay 2020April 2024Allow4731YesNo
16648967ANTI-HLA-A2 ANTIBODIES AND METHODS OF USING THE SAMEMarch 2020March 2024Allow4821NoNo
16645597COMPOSITIONS AND METHODS FOR REGULATION OF IMMUNE CELL ACTIVATION AND PROLIFERATIONMarch 2020January 2025Abandon5841NoNo
16645428STREP-TAG SPECIFIC BINDING PROTEINS AND USES THEREOFMarch 2020September 2024Abandon5441NoNo
16808058Methods for Treating Patients with Hyperlipidemia by Administering a PCSK9 Inhibitor in Combination with an ANGPTL3 InhibitorMarch 2020October 2023Allow4421NoNo
16784970ANTIBODIES THAT BIND HUMAN PROTEIN TYROSINE PHOSPHATASE beta (HPTPbeta) AND USES THEREOFFebruary 2020June 2023Allow4121YesNo
16632265METHODS OF QUALITATIVELY AND/OR QUANTITATIVELY ANALYZING PROPERTIES OF ACTIVATABLE ANTIBODIES AND USES THEREOFJanuary 2020June 2025Allow6021NoYes
16609053METHOD FOR PREDICTING AND EVALUATING THERAPEUTIC EFFECT IN DISEASES RELATED TO IL-6 AND NEUTROPHILSOctober 2019March 2023Allow4131YesNo
16663791COMPOUND HAVING AFFINITY SUBSTANCE TO SOLUBLE PROTEIN, CLEAVABLE PORTION AND REACTIVE GROUP, OR SALT THEREOFOctober 2019April 2024Allow5320YesNo
16661669Binding AgentsOctober 2019November 2023Allow4931YesNo
16500162ANTI-MASP-1 ANTIBODIES AND METHODS OF USEOctober 2019July 2023Allow4621NoNo
16484504CAR T-CELLS COMPRISING INACTIVATED CBL AND CBL-B GENESAugust 2019September 2024Allow6031YesNo
16480367ANTIGEN BINDING MOLECULES THAT BIND LIGHTJuly 2019June 2023Allow4721YesNo
16475876Biomarkers For Detecting Human Glycogen Phosphorylase Isoenzyme BBJuly 2019September 2024Abandon6021YesNo
16097021COMPOSITIONS AND METHODS FOR TREATING CANCEROctober 2018February 2024Abandon6031NoNo
15452669Treating LymphomasMarch 2017February 2025Allow60130NoNo
15173186METHOD OF TREATING MULTIPLE SCLEROSIS USING ANTI-CD20 ANTIBODIESJune 2016February 2019Allow3212YesNo
15027757METHODS OF IDENTIFYING SUBJECTS RESPONSIVE TO TREATMENT FOR TYPE 1 DIABETES AND COMPOSITIONS FOR TREATING THE SAMEApril 2016August 2024Allow6092YesYes
14979092ANTI-PCSK9 ANTIBODIES AND USE THEREOFDecember 2015November 2018Allow3511NoNo
14844475Methods for Treating Congestive Heart FailureSeptember 2015October 2018Allow3821YesNo
14603231METHOD FOR TREATING MUSCLE WASTING SYNDROME USING ANTAGONIST ANTIBODIES AGAINST GDF-8January 2015November 2017Allow3401YesNo
14571433NUCLEIC ACID ENCODING ANTIBODIES BINDING TO THE EXTRACELLULAR DOMAIN OF THE RECEPTOR TYROSINE KINASE ALKDecember 2014August 2016Allow2001NoNo
14562546NUCLEIC ACIDS ENCODING AN ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)December 2014June 2015Allow651YesYes
14123533ANTI-C-MET ANTIBODY HAVING HGF ACTIVITY AND USE THEREOFMarch 2014December 2016Allow3601YesNo
14189288ANTIBODIES AGAINST FATTY ACID SYNTHASEFebruary 2014January 2016Allow2300YesNo
14235970ANTIBODIES BINDING TO PHOSPHORYLCHOLINE (PC) AND/OR PC CONJUGATESJanuary 2014August 2017Allow4321YesNo
14155903PHOSPHORYLCHOLINE CONJUGATES AND CORRESPONDING ANTIBODIESJanuary 2014October 2018Allow5731YesNo
13883444MMP8 INACTIVATING ANTIGEN BINDING PROTEINSOctober 2013July 2017Allow5021YesNo
13940579VACCINE IMMUNOTHERAPY FOR TREATING HEPATOCELLULAR CANCER IN IMMUNE SUPPRESSED PATIENTSJuly 2013February 2014Allow701YesNo
13910834METHOD FOR TREATING SARCOPENIA USING ANTAGONIST ANTIBODIES AGAINST GDF-8June 2013September 2014Allow1600NoNo
13886180FORMULATIONS COMPRISING PCSK9 SPECIFIC MONOCLONAL ANTIBODIESMay 2013September 2019Allow6041YesNo
13655984ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)October 2012December 2023Abandon6081YesYes
13605341METHODS OF DETECTING OXIDIZED CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE IISeptember 2012May 2015Allow3200YesNo
13589652HEPATOCYTE GROWTH FACTOR (HGF) BINDING PROTEINSAugust 2012June 2013Allow1000NoNo
13576621METHODS FOR TREATMENT OF CUSHING'S DISEASE AND HYPERCORTISOLISM USING GEFITINIBAugust 2012March 2016Allow4321NoNo
13562863USE OF GOAT SERUM FOR VETERINARY TREATMENTJuly 2012August 2013Allow1311NoNo
13547548POLYNUCLEOTIDE ENCODING ANTI-CD14 ANTIBODY FUSION PROTEINJuly 2012May 2013Allow1001YesNo
13524465COMPLEMENT INHIBITORS AND USES THEREOFJune 2012August 2014Allow2621NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner WEN, SHARON X.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
2
Examiner Affirmed
2
(100.0%)
Examiner Reversed
0
(0.0%)
Reversal Percentile
0.5%
Lower than average

What This Means

With a 0.0% reversal rate, the PTAB affirms the examiner's rejections in the vast majority of cases. This reversal rate is in the bottom 25% across the USPTO, indicating that appeals face significant challenges here.

Strategic Value of Filing an Appeal

Total Appeal Filings
19
Allowed After Appeal Filing
4
(21.1%)
Not Allowed After Appeal Filing
15
(78.9%)
Filing Benefit Percentile
24.3%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 21.1% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner WEN, SHARON X - Prosecution Strategy Guide

Executive Summary

Examiner WEN, SHARON X works in Art Unit 1641 and has examined 170 patent applications in our dataset. With an allowance rate of 83.5%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 34 months.

Allowance Patterns

Examiner WEN, SHARON X's allowance rate of 83.5% places them in the 52% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by WEN, SHARON X receive 1.80 office actions before reaching final disposition. This places the examiner in the 54% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by WEN, SHARON X is 34 months. This places the examiner in the 22% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +18.7% benefit to allowance rate for applications examined by WEN, SHARON X. This interview benefit is in the 65% percentile among all examiners. Recommendation: Interviews provide an above-average benefit with this examiner and are worth considering.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 30.6% of applications are subsequently allowed. This success rate is in the 53% percentile among all examiners. Strategic Insight: RCEs show above-average effectiveness with this examiner. Consider whether your amendments or new arguments are strong enough to warrant an RCE versus filing a continuation.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 47.1% of cases where such amendments are filed. This entry rate is in the 66% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 120.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 80% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences are highly effective with this examiner compared to others. Before filing a full appeal brief, strongly consider requesting a PAC. The PAC provides an opportunity for the examiner and supervisory personnel to reconsider the rejection before the case proceeds to the PTAB.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 83.3% of appeals filed. This is in the 73% percentile among all examiners. Of these withdrawals, 90.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner shows above-average willingness to reconsider rejections during appeals. The mandatory appeal conference (MPEP § 1207.01) provides an opportunity for reconsideration.

Petition Practice

When applicants file petitions regarding this examiner's actions, 61.0% are granted (fully or in part). This grant rate is in the 78% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 18.2% of allowed cases (in the 99% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 0.0% of allowed cases (in the 2% percentile). This examiner rarely issues Quayle actions compared to other examiners. Allowances typically come directly without a separate action for formal matters.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Request pre-appeal conferences: PACs are highly effective with this examiner. Before filing a full appeal brief, request a PAC to potentially resolve issues without full PTAB review.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.