USPTO Examiner HILL KEVIN KAI - Art Unit 1638

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18933687GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING GENETICALLY CORRECTED AUTOLOGOUS KERATINOCYTESOctober 2024June 2025Allow720NoNo
18501837GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING GENETICALLY CORRECTED AUTOLOGOUS KERATINOCYTESNovember 2023August 2024Allow1021NoNo
18119201GENE THERAPY FOR NIEMANN-PICK DISEASE TYPE AMarch 2023June 2025Abandon2710YesNo
18152699VIRAL DELIVERY OF NEOANTIGENSJanuary 2023June 2025Abandon2910NoNo
18145996RNA-Guided Systems for In Vivo Gene EditingDecember 2022April 2025Allow2810YesNo
18067283GENE THERAPYDecember 2022April 2025Abandon2810NoNo
18058126GENE THERAPY FOR TREATING FAMILIAL HYPERCHOLESTEROLEMIANovember 2022May 2025Abandon2910NoNo
18057572GENE THERAPY FOR TREATING CITRULLENEMIANovember 2022April 2025Allow2810NoNo
17976062GENE DELIVERY SYSTEM CONTAINING RELAXIN GENE AND PHARMACEUTICAL COMPOSITION USING RELAXINOctober 2022April 2025Abandon2910NoNo
17663242SYNP88, A PROMOTER FOR THE EXPRESSION OF GENESMay 2022February 2025Abandon3310NoNo
17577940ADMINISTRATION OF TUMOR INFILTRATING LYMPHOCYTES WITH MEMBRANE BOUND INTERLEUKIN 15 TO TREAT CANCERJanuary 2022February 2024Abandon2540NoNo
17646212DHFR TUNABLE PROTEIN REGULATIONDecember 2021May 2024Allow2851NoNo
17545632METHODS FOR EXTENDING THE REPLICATIVE CAPACITY OF SOMATIC CELLS DURING AN EX VIVO CULTIVATION PROCESSDecember 2021November 2024Abandon3501NoNo
17543148CHIMERIC ANTIGEN RECEPTORS TARGETING HER2December 2021February 2025Abandon3801NoNo
17478488INDUCED ACTIVATION IN DENDRITIC CELLSSeptember 2021December 2024Abandon3910NoNo
17472284DRUG REGULATED TRANSGENE EXPRESSIONSeptember 2021October 2024Allow3810YesNo
17407782INTRATHECAL ADMINISTRATION OF ADENO-ASSOCIATED-VIRAL VECTORS FOR GENE THERAPYAugust 2021May 2025Abandon4411NoNo
17403138Hepatocyte Based Insulin Gene Therapy for DiabetesAugust 2021August 2024Allow3610NoNo
17401474NUCLEATED CELL PRESERVATION BY LYOPHILIZATIONAugust 2021October 2024Abandon3801NoNo
17385265IMMUNOMODULATORY ONCOLYTIC ADENOVIRAL VECTORS, AND METHODS OF PRODUCTION AND USE THEREOF FOR TREATMENT OF CANCERJuly 2021September 2024Abandon3810NoNo
17365845AAV VECTOR FOR TREATMENT OF FRIEDREICH'S ATAXIAJuly 2021June 2025Abandon4730NoNo
17356214COMPOSITIONS AND METHODS FOR DELIVERING CFTR POLYPEPTIDESJune 2021July 2024Abandon3710NoNo
17240714Methods and Compositions Related to Annexin 1-Binding CompoundsApril 2021September 2024Abandon4111NoNo
17224524HUMANIZED RODENTS THAT EXPRESS HEAVY CHAIN CONTAINING VL DOMAINSApril 2021July 2024Abandon3910NoNo
17222659ADENO-ASSOCIATED VIRUS COMPOSITIONS FOR IDS GENE TRANSFER AND METHODS OF USE THEREOFApril 2021April 2024Abandon3711NoNo
17276112MODIFIED MRNA FOR THE TREATMENT OF PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS DISORDERSMarch 2021February 2025Abandon4711NoNo
17200725ONCOLYTIC VACCINIA VIRUS CANCER THERAPYMarch 2021May 2024Abandon3801NoNo
17143019RECOMBINANT PROMOTERS AND VECTORS FOR PROTEIN EXPRESSION IN LIVER AND USE THEREOFJanuary 2021July 2024Abandon4210NoNo
17134483COMPOSITIONS FOR CONFERRING TOLERANCE TO VIRAL DISEASE IN SOCIAL INSECTS, AND THE USE THEREOFDecember 2020June 2024Abandon4110NoNo
17131688HIGH AFFINITY MAGE-A1-SPECIFIC TCRS AND USES THEREOFDecember 2020February 2024Abandon3810NoNo
17120743MODULATION OF TISSUE FATTY ACID COMPOSITION OF A HOST BY HUMAN GUT BACTERIADecember 2020February 2024Abandon3810NoNo
17116168RECOMBINANT AAVS HAVING USEFUL TRANSCYTOSIS PROPERTIESDecember 2020May 2024Abandon4120NoNo
17116098Adeno Associated Virus Vectors for the Treatment of Hunter DiseaseDecember 2020September 2023Allow3311YesNo
17105022BRAIN REPAIR AFTER TRAUMATIC BRAIN INJURY THROUGH NEUROD1-MEDIATED ASTROCYTE-TO-NEURON CONVERSIONNovember 2020May 2025Abandon5441NoNo
17099942RODENTS HAVING A HUMANIZED TMPRSS GENENovember 2020October 2023Allow3510NoNo
17092239RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR FOR GENE DELIVERYNovember 2020August 2024Allow4631NoNo
17053198BLOOD PRODUCT DERIVED FROM GENE KNOCKOUT PIG AND USE THEREOFNovember 2020August 2024Abandon4511NoNo
17051197RAAV-MEDIATED NUCLEASE-ASSOCIATED VECTOR INTEGRATION (RAAV-NAVI)October 2020July 2024Abandon4511NoNo
17079380METHODS AND AGENTS FOR ENHANCING T CELL THERAPIESOctober 2020February 2024Abandon4021NoNo
17069305METHODS AND COMPOSITIONS FOR LOCALIZED AGENT DELIVERYOctober 2020May 2024Abandon4311NoNo
17024424ANTIBODY GENE THERAPY FOR TREATMENT AND PREVENTION OF INFECTION BY RABIES LYSSAVIRUSSeptember 2020June 2025Abandon5741NoNo
17021526NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOFSeptember 2020February 2025Abandon5340NoNo
17015925Functionalized DNA Dendrimers For Gene Delivery To CellsSeptember 2020February 2024Abandon4220NoNo
16971801SEQUENCING METHOD FOR CAR T CELL THERAPYAugust 2020September 2024Allow4911YesNo
16992689GENE AUGMENTATION THERAPIES FOR INHERITED RETINAL DEGENERATION CAUSED BY MUTATIONS IN THE PRPF31 GENEAugust 2020December 2024Abandon5221NoYes
16989454Ancestral Virus Sequences and Uses ThereofAugust 2020May 2024Allow4530YesNo
16900178METHODS AND COMPOSITIONS FOR NON-CYTOTOXIC STEM CELL TRANSPLANTATIONJune 2020March 2024Abandon4670YesYes
16870445COMPOSITIONS TO DISRUPT PROTEIN KINASE A ANCHORING AND USES THEREOFMay 2020April 2024Abandon4821NoNo
16809300ANALYSIS OF GENOMIC DNA, RNA, AND PROTEINS IN EXOSOMES FOR DIAGNOSIS AND THERANOSISMarch 2020May 2024Abandon5021NoNo
16797527GENE THERAPY TO IMPROVE VISIONFebruary 2020June 2025Abandon6041NoNo
16637447METHODS AND COMPOSITIONS FOR PREPARING GENETICALLY ENGINEERED CELLSFebruary 2020May 2024Abandon5131NoNo
16743772TARGETING CYTOTOXIC CELLS WITH CHIMERIC RECEPTORS FOR ADOPTIVE IMMUNOTHERAPYJanuary 2020December 2023Allow4741NoNo
16616713CBLB ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USENovember 2019September 2024Allow5851YesNo
16613907GENE THERAPY FOR TUBEROUS SCLEROSISNovember 2019December 2023Allow4930YesNo
16604675MULTIPLE TRANSGENE RECOMBINANT ADENOVIRUSOctober 2019February 2024Allow5341NoNo
16604475ADENO-ASSOCIATED VIRUS LIBRARYOctober 2019April 2024Abandon5531NoNo
16498592OXIDATION-RESISTANT AAT GENE THERAPYSeptember 2019February 2024Allow5341YesNo
16495826Gene Therapy for the Treatment of CNGB1-linked Retinitis PigmentosaSeptember 2019November 2024Allow6051NoNo
16482049TUMOR SELECTIVE TATA-BOX AND CAAT-BOX MUTANTSJuly 2019April 2025Abandon6061NoNo
16513566METHODS AND COMPOSITIONS OF OTC CONSTRUCTS AND VECTORSJuly 2019June 2025Abandon6031NoYes
16477168POLYNUCLEOTIDES AND VECTORS FOR THE EXPRESSION OF TRANSGENESJuly 2019November 2023Allow5241NoNo
16475926GENETICALLY MODIFIED NK-92 CELLS WITH DECREASED CD96/TIGIT EXPRESSIONJuly 2019November 2024Abandon6061YesYes
16456773RNA VIRUSES EXPRESSING IL-12 FOR IMMUNOVIROTHERAPYJune 2019August 2023Abandon4951NoYes
16428348METHODS FOR GENOME-EDITING AND ACTIVATION OF CELLSMay 2019June 2024Abandon6041NoNo
16290357COMPOSITIONS FOR DELIVERY OF CARGO TO CELLSMarch 2019December 2024Abandon6070NoNo
16253056Immunomodulatory Oncolytic Adenoviral Vectors, and Methods of Production and Use Thereof for Treatment of CancerJanuary 2019February 2024Abandon6041NoNo
16250679METHODS OF ASSESSING POTENCY OF VIRAL VECTORSJanuary 2019October 2024Abandon6060YesNo
16315362AAV2-MEDIATED GENE DELIVERY OF SFASL AS A NEUROPROTECTIVE THERAPY IN GLAUCOMAJanuary 2019June 2024Abandon6041NoYes
16308196A NOVEL ROLE FOR TERMINAL RNA URIDYLATION AND RNA TURNOVER IN ONCOGENESISDecember 2018December 2024Abandon6041YesNo
16307462METHODS FOR THE TREATMENT OF B CELL MALIGNANCIES USING ADOPTIVE CELL THERAPYDecember 2018February 2025Abandon6061NoNo
16091967USE OF HETERODIMERIC IL-15 IN ADOPTIVE CELL TRANSFEROctober 2018September 2024Abandon6060NoNo
16066253GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING GENETICALLY CORRECTED AUTOLOGOUS KERATINOCYTESJune 2018October 2024Allow6091YesNo
15771683USE OF MAPK INHIBITORS TO REDUCE LOSS OF HEMATOPOIETIC STEM CELLS DURING EX VIVO CULTURE AND/OR GENETIC MANIPULATIONApril 2018June 2025Abandon6061YesYes
15771849Gene TherapyApril 2018June 2024Abandon6080YesYes
15753003BAG3 COMPOSITIONS AND METHODSFebruary 2018June 2024Abandon6080YesNo
15838824TLR AGONISTS FOR REDUCING ACTIVATION-INDUCED PD-1 EXPRESSION ON T CELLS AND METHODS OF USEDecember 2017April 2024Abandon6070NoNo
15557263IL-10-PRODUCING CD4+ T CELLS AND USES THEREOFSeptember 2017March 2025Abandon6081YesYes
15552163SITE-SPECIFIC INTEGRATING RECOMBINANT AAV VECTORS FOR GENE THERAPY AND IMPROVED PRODUCTION METHODSAugust 2017September 2024Abandon6071YesNo
15520633TRIPLE TRANSGENIC PIGS SUITABLE FOR XENOGRAFTApril 2017July 2024Abandon6061YesYes
15259797METHODS AND COMPOSITIONS FOR THE PACKAGING OF NUCLEIC ACIDS INTO MICROGLIAL EXOSOMES FOR THE TARGETED EXPRESSION OF POLYPEPTIDES IN NEURAL CELLSSeptember 2016September 2017Allow1201NoNo
14846952METHODS AND COMPOSITIONS FOR ATTENUATING GENE THERAPY ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSESSeptember 2015January 2025Abandon60111NoYes
14772361Placental Like Alkaline Phosphatase (PLAP) Promoter Mediated Cell TargetingSeptember 2015June 2017Allow2231YesNo
14763283APTAMERS FOR TUMOR INITIATING CELLSJuly 2015November 2016Allow1611YesNo
14740890SEQUENCE OF NUCLEOTIDES AND PEPTIDES GSE 24.2 OF DYSKERIN, WHICH CAN INDUCE TELOMERASE ACTIVITY, METHOD FOR OBTAINING SAME, THERAPEUTIC COMPOSITIONS AND APPLICATIONS THEREOFJune 2015November 2016Allow1711NoNo
14492334MANNOSE-CONTAINING SOLUTION FOR LYOPHILIZATION, TRANSFECTION AND/OR INJECTION OF NUCLEIC ACIDSSeptember 2014December 2016Allow2621NoNo
14289043Soft Tissue and Bone Augmentation and Bulking Utilizing Muscle-Derived Progenitor Cells, Compositions and Treatments ThereofMay 2014May 2016Allow2411NoNo
14242648NOVEL VIRAL VECTOR CONSTRUCT FOR NEURON SPECIFIC OPTIMIZED CONTINUOUS DOPA SYNTHESIS IN VIVOApril 2014November 2016Allow3321YesNo
14220099ANIMALS, REPERTOIRES & METHODSMarch 2014March 2024Abandon60101NoNo
14161656SMALL MOLECULES SUPPORTING PLURIPOTENT CELL GROWTH AND METHODS THEREOFJanuary 2014May 2016Allow2811YesNo
13613338BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALSSeptember 2012November 2013Allow1401NoNo
13511353T CELL RECEPTORS SPECIFIC FOR IMMUNODOMINANT CTL EPITOPES OF HCVAugust 2012November 2013Allow1811YesNo
13543059STEM CELL CAPTURE AND IMMOBILIZATION COATINGS FOR MEDICAL DEVICES AND IMPLANTSJuly 2012April 2013Allow910YesNo
13514913METHOD FOR DIAGNOSIS/PROGNOSIS OF CANCERS USING AN EPIGENETIC MARKER CONSISTING OF A SPECIFIC SINGLE CPG SITE IN TTP PROMOTER AND TREATMENT OF CANCERS BY REGULATING ITS EPIGENETIC STATUSJune 2012December 2013Allow1811YesNo
13384435THERAPEUTIC AGENTSMay 2012October 2013Allow2111YesNo
13301475COMPOSITIONS AND METHODS FOR REGULATING ANGIOGENESISNovember 2011March 2015Allow4021YesNo
13259151SMALL MOLECULES SUPPORTING PLURIPOTENT CELL GROWTH AND METHODS THEREOFSeptember 2011October 2013Allow2521YesNo
13038827SOFT TISSUE AND BONE AUGMENTATION AND BULKING UTILIZING MUSCLE-DERIVED PROGENITOR CELLS, COMPOSITIONS AND TREATMENTS THEREOFMarch 2011November 2013Allow3230NoNo
12681243NOVEL PROTEIN TRANSDUCTION DOMAINS DERIVED FROM SECRETORY LEUKOCYTE PROTEASE INHIBITORDecember 2010July 2013Allow4011YesNo
12993517Method For Characterising The Biological Activity Of Helminth Eggs, In Particular Trichuris EggsDecember 2010December 2014Allow4821YesNo
12952863MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY UTILIZING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDESNovember 2010February 2012Allow1411NoNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner HILL, KEVIN KAI.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
3
Examiner Affirmed
2
(66.7%)
Examiner Reversed
1
(33.3%)
Reversal Percentile
48.4%
Lower than average

What This Means

With a 33.3% reversal rate, the PTAB reverses the examiner's rejections in a meaningful percentage of cases. This reversal rate is below the USPTO average, indicating that appeals face more challenges here than typical.

Strategic Value of Filing an Appeal

Total Appeal Filings
17
Allowed After Appeal Filing
3
(17.6%)
Not Allowed After Appeal Filing
14
(82.4%)
Filing Benefit Percentile
18.7%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 17.6% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Appeals to PTAB face challenges. Ensure your case has strong merit before committing to full Board review.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner HILL, KEVIN KAI - Prosecution Strategy Guide

Executive Summary

Examiner HILL, KEVIN KAI works in Art Unit 1638 and has examined 130 patent applications in our dataset. With an allowance rate of 53.1%, this examiner allows applications at a lower rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 44 months.

Allowance Patterns

Examiner HILL, KEVIN KAI's allowance rate of 53.1% places them in the 9% percentile among all USPTO examiners. This examiner is less likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by HILL, KEVIN KAI receive 3.03 office actions before reaching final disposition. This places the examiner in the 96% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by HILL, KEVIN KAI is 44 months. This places the examiner in the 2% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +46.7% benefit to allowance rate for applications examined by HILL, KEVIN KAI. This interview benefit is in the 93% percentile among all examiners. Recommendation: Interviews are highly effective with this examiner and should be strongly considered as a prosecution strategy. Per MPEP § 713.10, interviews are available at any time before the Notice of Allowance is mailed or jurisdiction transfers to the PTAB.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 12.7% of applications are subsequently allowed. This success rate is in the 4% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 35.2% of cases where such amendments are filed. This entry rate is in the 45% percentile among all examiners. Strategic Recommendation: This examiner shows below-average receptiveness to after-final amendments. You may need to file an RCE or appeal rather than relying on after-final amendment entry.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 0.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 1% percentile among all examiners. Note: Pre-appeal conferences show limited success with this examiner compared to others. While still worth considering, be prepared to proceed with a full appeal brief if the PAC does not result in favorable action.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 57.1% of appeals filed. This is in the 24% percentile among all examiners. Of these withdrawals, 50.0% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner rarely withdraws rejections during the appeal process compared to other examiners. If you file an appeal, be prepared to fully prosecute it to a PTAB decision. Per MPEP § 1207, the examiner will prepare an Examiner's Answer maintaining the rejections.

Petition Practice

When applicants file petitions regarding this examiner's actions, 81.6% are granted (fully or in part). This grant rate is in the 93% percentile among all examiners. Strategic Note: Petitions are frequently granted regarding this examiner's actions compared to other examiners. Per MPEP § 1002.02(c), various examiner actions are petitionable to the Technology Center Director, including prematureness of final rejection, refusal to enter amendments, and requirement for information. If you believe an examiner action is improper, consider filing a petition.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 11.5% of allowed cases (in the 97% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 2.9% of allowed cases (in the 71% percentile). This examiner issues Quayle actions more often than average when claims are allowable but formal matters remain (MPEP § 714.14).

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Prepare for rigorous examination: With a below-average allowance rate, ensure your application has strong written description and enablement support. Consider filing a continuation if you need to add new matter.
  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Prioritize examiner interviews: Interviews are highly effective with this examiner. Request an interview after the first office action to clarify issues and potentially expedite allowance.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.