USPTO Examiner ZARA JANE J - Art Unit 1637

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18955967DRUGS FOR PREVENTION OR TREATMENT OF SEPSISNovember 2024January 2025Allow200NoNo
18864911SIRNA SPECIFICALLY BINDING TO M2 MACROPHAGE CD206 AND APPLICATION THEREOFNovember 2024June 2025Allow710NoNo
18930307METHOD FOR PREVENTING DSRNA BACTERIAL SOLUTIONS FROM BEING DEGRADED BY UVLIGHT AND APPLICATION THEREOF IN CONTROL OF SILVERLEAF WHITEFLIESOctober 2024March 2025Allow410NoNo
18801051SYNTHETIC SELF-AMPLIFYING MRNA MOLECULES WITH SECRETION ANTIGEN AND IMMUNOMODULATORAugust 2024May 2025Allow911YesNo
18793716APPLICATION OF MECHANICAL-FORCE SENSITIVE MACROPHAGE SUBSET IN PANCREATIC CANCER DIAGNOSIS OR PROGNOSIS EVALUATIONAugust 2024June 2025Allow1020NoNo
18751048ADVANCED RNA TARGETING (ARNATAR) FOR ANGIOTENSINOGENJune 2024December 2024Allow611YesNo
18660600COMPOUNDS TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASEMay 2024April 2025Allow1111YesNo
18654906REAGENTS AND METHODS USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDESMay 2024October 2024Allow511YesNo
18427866SIGNAL BOOST CASCADE ASSAYJanuary 2024July 2024Allow530NoNo
18387017cGMP EXOSOME LOADED THERAPEUTICS FOR TREATING SICKLE CELL DISEASENovember 2023January 2025Allow1520YesNo
18467224COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNASSeptember 2023November 2024Allow1431YesNo
18467190COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTSSeptember 2023April 2024Allow710NoNo
18234402SIGNAL BOOST CASCADE ASSAYAugust 2023January 2024Allow511NoNo
18260789USE OF GANODERMA FUNGAL RNA MOLECULES, DRUG, DRUG COMPOSITION AND DELIVERY CARRIERJuly 2023May 2025Allow2220NoNo
18327434RECONFIGURABLE DNA NANO-TWEEZERJune 2023March 2025Allow2210NoNo
18169779VARIANT RNAiFebruary 2023February 2025Allow2400NoNo
18159465LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOFJanuary 2023May 2025Allow2820NoNo
18148396MODIFICATIONS OF MAMMALIAN CELLS USING ARTIFICIAL MICRO-RNA TO ALTER THEIR PROPERTIES AND THE COMPOSITIONS OF THEIR PRODUCTSDecember 2022March 2025Allow2621NoNo
18057809METHODS AND COMPOSITIONS FOR STUDYING CELL EVOLUTIONNovember 2022May 2025Allow3011NoNo
17989526NOVEL POLYINOSINIC - POLYCYTIDYLIC ACID COMPOSITIONS AND METHODS OF MAKING SAMENovember 2022May 2025Allow3030NoNo
17988625NOVEL POLYINOSINIC - POLYCYTIDYLIC ACID COMPOSITIONSNovember 2022April 2025Allow2910NoNo
17949048USE OF P38 INHIBITORS TO REDUCE EXPRESSION OF DUX4September 2022March 2025Abandon3001NoNo
17898292RIG-I Agonists and Methods of Using SameAugust 2022June 2025Abandon3310NoNo
17818656DE NOVO SYNTHESIZED GENE LIBRARIESAugust 2022June 2025Allow3421YesNo
17881471IMPORT OF UNNATURAL OR MODIFIED NUCLEOSIDE TRIPHOSPHATES INTO CELLS VIA NUCLEIC ACID TRIPHOSPHATE TRANSPORTERSAugust 2022June 2025Allow3420NoNo
17816696RNA POLYMERASE VARIANTS FOR CO-TRANSCRIPTIONAL CAPPINGAugust 2022July 2024Allow2300NoNo
17864129Use of Telomerase Inhibitors for the Treatment of Myeloproliferative Disorders and Myeloproliferative NeoplasmsJuly 2022February 2025Abandon3101NoNo
17826252COMPOUNDS AND METHODS OF PROMOTING MYELINATIONMay 2022April 2025Allow3511NoNo
17752530METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITROMay 2022January 2025Allow3210YesNo
17734460PARTICLES AND COMPOSITIONS COMPRISING THE SAME FOR TRANSFECTIONMay 2022December 2024Abandon3210NoNo
17773545THERAPEUTIC DOUBLE STRANDED RNA AND METHODS FOR PRODUCING THE SAMEApril 2022April 2025Allow3641NoYes
17731259METHOD OF STIMULATING PROLIFERATION OF A CELLApril 2022May 2025Allow3711YesNo
17658075IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOFApril 2022January 2025Allow3311NoNo
17677875MODULATORS OF DIACYGLYCEROL ACYLTRANSFERASE 2 (DGAT2)February 2022September 2024Allow3101NoNo
17558705METHODS FOR DIAGNOSING AND TREATING METASTATIC CANCERDecember 2021May 2025Allow4121YesNo
17538217COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTSNovember 2021February 2025Allow3811NoNo
17535191METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER OR OTHER DISEASESNovember 2021March 2025Abandon3910NoNo
17612120NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF C3 IN A CELLNovember 2021December 2024Abandon3701NoNo
17528828COMPOSITIONS AND METHODS FOR INTERNALIZING ENZYMESNovember 2021September 2024Allow3411NoNo
17523060HIGH PURITY RNA COMPOSITIONS AND METHODS FOR PREPARATION THEREOFNovember 2021September 2024Allow3510NoNo
17523034HIGH PURITY RNA COMPOSITIONS AND METHODS FOR PREPARATION THEREOFNovember 2021October 2024Allow3610NoNo
17512280METHOD AND COMPOSITION FOR TARGETED DELIVERY OF THERAPEUTIC AGENTSOctober 2021November 2024Abandon3710NoNo
17509648METHODS OF MEASURING C19MC miRNA IN A POST-NATAL TISSUE AND USES THEREOFOctober 2021February 2025Allow3921NoNo
17448996Composition and Methods for Treatment of Ornithine Transcarbamylase DeficiencySeptember 2021December 2024Allow3811NoNo
17405482MicroRNA Compounds and Methods for Modulating MIR-21 ActivityAugust 2021February 2025Allow4221NoNo
17398490CONJUGATED ANTISENSE COMPOUNDS AND THEIR USEAugust 2021December 2024Abandon4010NoNo
17375658OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOFJuly 2021February 2025Allow4311NoNo
17420195METHOD AND APPARATUS FOR INVESTIGATING INTRA- AND/OR INTERMOLECULAR INTERACTIONS INVOLVING RNAJuly 2021December 2024Allow4101NoNo
17354818METHODS AND COMPOSITIONS FOR TREATING HEMOPHILIAJune 2021December 2024Allow4141YesNo
17335499CLOSED-ENDED LINEAR DUPLEX DNA FOR NON-VIRAL GENE TRANSFERJune 2021November 2024Allow4111NoNo
17332249CHIMERIC DOUBLE-STRANDED NUCLEIC ACIDMay 2021April 2025Allow4731NoNo
17292710COMPOSITION COMPRISING APTAMER AS ACTIVE INGREDIENT FOR TREATMENT AND PREVENTION OF DEGENERATIVE BRAIN DISEASEMay 2021October 2024Allow4110NoNo
17292292MINI-NUCLEOSOME CORE PROTEINS AND USE IN NUCLEIC ACID DELIVERYMay 2021June 2025Allow4941NoNo
17308888NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOFMay 2021September 2024Allow4131YesNo
17237856Compositions of Asymmetric Interfering RNA and Uses ThereofApril 2021March 2025Allow4621NoNo
17221867SHORT INTERFERING RNA TEMPLATED LIPOPROTEIN PARTICLES (SIRNA-TLP)April 2021October 2024Abandon4311NoNo
17279574METHODS FOR MONITORING RESPONSE TO TREATMENTMarch 2021January 2025Abandon4610NoNo
17276898SUBSTRATE FOR NUCLEIC ACID ANALYSIS, FLOW CELL FOR NUCLEIC ACID ANALYSIS, AND IMAGE ANALYSIS METHODMarch 2021October 2024Abandon4301NoNo
17194706Methods of Treating PorphyriaMarch 2021August 2024Allow4121NoNo
17194821MUTANT CSGG PORESMarch 2021November 2024Allow4511NoNo
17193999IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOFMarch 2021January 2025Allow4711NoNo
17191222COMPOSITIONS FOR SELECTION OF APTAMERSMarch 2021February 2025Abandon4720NoNo
17187669NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOFFebruary 2021October 2024Allow4331YesNo
17144365Silencing of HNF4A-P2 Isoforms with siRNA to Improve Hepatocyte Function in Liver FailureJanuary 2021August 2024Allow4421YesNo
17258880METHODS FOR QUANTITATION OF ANALYTES IN MULTIPLEXED BIOCHEMICAL REACTIONSJanuary 2021March 2025Abandon5111NoNo
17130908COMPOSITIONS AND METHODS FOR THE TREATMENT OF EXPANDED REPEAT-ASSOCIATED DISORDERSDecember 2020August 2024Allow4421NoYes
17251921RIG-I Agonists and Treatments Using SameDecember 2020February 2025Allow5021NoNo
17117025C/EBP ALPHA SARNA COMPOSITIONS AND METHODS OF USEDecember 2020May 2025Abandon5321NoYes
17058817Methods for the Treatment of Bladder CancerNovember 2020July 2024Allow4420YesNo
17047011THERAPEUTIC CONSTRUCTS FOR TREATING CANCEROctober 2020October 2024Allow4811NoNo
17026473METHOD OF SYNTHESIS OF AN IONIZABLE CATIONIC LIPIDSeptember 2020December 2024Allow5120NoNo
17016313CHIRAL DESIGNSeptember 2020February 2023Allow2920NoNo
16967926PROCESS TO INHIBIT OR ELIMINATE EOSINOPHILIC DISEASES OF THE AIRWAY AND RELATED CONDITIONSAugust 2020November 2024Abandon5111NoNo
16966430POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEMJuly 2020August 2024Allow4921YesNo
16927346METHODS AND MATERIALS FOR DISCOVERY OF FUNCTIONAL LIGANDS TO MOLECULAR COMPLEXESJuly 2020February 2025Allow5511NoNo
16147844NOVEL RNA CONSTRUCT AND METHODS OF USE THEREOF FOR ENHANCING THE THERAPEUTIC EFFECTS OF CYTOTOXIC CELLS AND STEM CELLSSeptember 2018September 2021Abandon3621NoNo
15779633THERAPEUTIC TARGETS FOR THE CORRECTION OF THE HUMAN DYSTROPHIN GENE BY GENE EDITING AND METHODS OF USEMay 2018September 2023Allow6061YesNo
15990542COMPOSITIONS WITH IMPROVED INTRAVITREAL HALF-LIFE AND USES THEREOFMay 2018January 2019Allow810NoNo
15536006SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR INHIBITING TGF-BETA1 EXPRESSIONJune 2017April 2019Allow2220NoNo
15513861Method for Assessing the Efficacy of IMIDS and Composition or Combination for Use in Treating IMID Sensitive DiseasesMarch 2017April 2019Allow2511NoNo
15508424OLIGONUCLEOTIDE TARGETED TO THE A20-THREE PRIME UNTRANSLATED REGIONMarch 2017May 2020Allow3841NoNo
15367947MIR-193A-3P AND ASSOCIATED GENES PREDICT TUMORIGENESIS AND CHEMOTHERAPY OUTCOMESDecember 2016August 2018Allow2010NoNo
15199139MICRO-RNA INHIBITORJune 2016November 2018Allow2821NoNo
15012052COMPOSITIONS, KITS AND METHODS FOR TREATMENT OF CARDIOVASCULAR,IMMUNOLOGICAL AND INFLAMMATORY DISEASESFebruary 2016July 2018Allow2920NoNo
15010837METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITROJanuary 2016February 2019Allow3721NoNo
14922954TREATMENT OF SEX HORMONE BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SHBGOctober 2015February 2020Allow5271NoNo
13653013COMPOSITIONS AND METHODS FOR SHORT INTERFERING NUCLEIC ACID INHIBITION OF NAV1.8October 2012January 2014Allow1501NoNo
13469402TREATMENT OF CANCER BY INHIBITION OF IGFBPS AND CLUSTERINMay 2012May 2013Allow1240NoNo
13466631SIRNA TARGETING CATENIN, BETA-1 (CTNNB1)May 2012November 2012Allow701NoNo
13386154POLYION COMPLEX COMPRISING PHD2 EXPRESSION INHIBITING SUBSTANCEMarch 2012January 2014Allow2422NoNo
13344303MOLECULAR TARGETS AND COMPOUNDS, AND METHODS TO IDENTIFY THE SAME, USEFUL IN THE TREATMENT OF JOINT DEGENERATIVE AND INFLAMMATORY DISEASESJanuary 2012November 2013Allow2221NoNo
13138224PHD2 INHIBITION FOR BLOOD VESSEL NORMALIZATION, AND USES THEREOFOctober 2011December 2013Allow2921NoNo
13246696USE OF A GROWTH-STIMULATING PROTEINSeptember 2011November 2012Allow1411NoNo
13087618TREATMENT OF CANCER BY INHIBITION OF IGFBPS AND CLUSTERINApril 2011May 2012Allow1320NoNo
13087627Treatment of Cancer by Inhibition of IGFBPs and ClusterinApril 2011March 2013Allow2330NoYes
13079525POTENT LNA OLIGONUCLEOTIDES FOR THE INHIBITION OF HIF-1A EXPRESSIONApril 2011November 2012Allow2010NoNo
13072915Method of Selectively Inhibiting the Activity of ACAT1 in the Treatment of Alzheimer's DiseaseMarch 2011February 2013Allow2311NoNo
12789564COMPOSITIONS AND METHODS FOR SHORT INTERFERING NUCLEIC ACID INHIBITION OF NAV1.8May 2010July 2012Allow2511NoNo
12600803MICRO-RNAS MODULATING IMMUNITY AND INFLAMMATIONMay 2010December 2012Allow3711NoNo
12597458MODULATION OF BLOOD BRAIN BARRIER PROTEIN EXPRESSIONApril 2010December 2012Allow3821YesNo

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner ZARA, JANE J.

Strategic Value of Filing an Appeal

Total Appeal Filings
14
Allowed After Appeal Filing
3
(21.4%)
Not Allowed After Appeal Filing
11
(78.6%)
Filing Benefit Percentile
24.9%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 21.4% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is in the bottom 25% across the USPTO, indicating that filing appeals is less effective here than in most other areas.

Strategic Recommendations

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner ZARA, JANE J - Prosecution Strategy Guide

Executive Summary

Examiner ZARA, JANE J works in Art Unit 1637 and has examined 202 patent applications in our dataset. With an allowance rate of 91.6%, this examiner allows applications at a higher rate than most examiners at the USPTO. Applications typically reach final disposition in approximately 39 months.

Allowance Patterns

Examiner ZARA, JANE J's allowance rate of 91.6% places them in the 76% percentile among all USPTO examiners. This examiner is more likely to allow applications than most examiners at the USPTO.

Office Action Patterns

On average, applications examined by ZARA, JANE J receive 1.92 office actions before reaching final disposition. This places the examiner in the 61% percentile for office actions issued. This examiner issues a slightly above-average number of office actions.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by ZARA, JANE J is 39 months. This places the examiner in the 9% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +9.9% benefit to allowance rate for applications examined by ZARA, JANE J. This interview benefit is in the 46% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 37.0% of applications are subsequently allowed. This success rate is in the 81% percentile among all examiners. Strategic Insight: RCEs are highly effective with this examiner compared to others. If you receive a final rejection, filing an RCE with substantive amendments or arguments has a strong likelihood of success.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 72.4% of cases where such amendments are filed. This entry rate is in the 92% percentile among all examiners. Strategic Recommendation: This examiner is highly receptive to after-final amendments compared to other examiners. Per MPEP § 714.12, after-final amendments may be entered "under justifiable circumstances." Consider filing after-final amendments with a clear showing of allowability rather than immediately filing an RCE, as this examiner frequently enters such amendments.

Pre-Appeal Conference Effectiveness

When applicants request a pre-appeal conference (PAC) with this examiner, 200.0% result in withdrawal of the rejection or reopening of prosecution. This success rate is in the 92% percentile among all examiners. Strategic Recommendation: Pre-appeal conferences are highly effective with this examiner compared to others. Before filing a full appeal brief, strongly consider requesting a PAC. The PAC provides an opportunity for the examiner and supervisory personnel to reconsider the rejection before the case proceeds to the PTAB.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 100.0% of appeals filed. This is in the 85% percentile among all examiners. Of these withdrawals, 92.3% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 53.7% are granted (fully or in part). This grant rate is in the 67% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 24.8% of allowed cases (in the 100% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 9.7% of allowed cases (in the 87% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Consider after-final amendments: This examiner frequently enters after-final amendments. If you can clearly overcome rejections with claim amendments, file an after-final amendment before resorting to an RCE.
  • RCEs are effective: This examiner has a high allowance rate after RCE compared to others. If you receive a final rejection and have substantive amendments or arguments, an RCE is likely to be successful.
  • Request pre-appeal conferences: PACs are highly effective with this examiner. Before filing a full appeal brief, request a PAC to potentially resolve issues without full PTAB review.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.