USPTO Examiner MARVICH MARIA - Art Unit 1634

Recent Applications

Detailed information about the 100 most recent patent applications.

Application NumberTitleFiling DateDisposal DateDispositionTime (months)Office ActionsRestrictionsInterviewAppeal
18885902COMPOSITION FOR REGULATING PRODUCTION OF FUSION PROTEINSSeptember 2024May 2025Allow810NoNo
18738959COMPOSITION FOR REGULATING PRODUCTION OF FUSION PROTEINSJune 2024January 2025Allow710YesNo
18427711NON-TRANSGENE TRANSFECTION FOR THERAPEUTIC PURPOSESJanuary 2024June 2025Allow1730YesNo
18474506Cross-Species Compatible Adeno-Associated Virus Compositions and Methods of Use ThereofSeptember 2023July 2024Allow910YesNo
18275591TARGETED EXTRACELLULAR VESICLES FOR DELIVERY OF THERAPEUTICSAugust 2023October 2024Allow1510NoNo
18351689ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLSJuly 2023November 2024Allow1620YesNo
18351800ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLSJuly 2023November 2024Allow1720YesNo
18351674ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVERY TO CELLSJuly 2023November 2024Allow1640YesNo
18322531METHODS AND COMPOSITIONS FOR TRANSDUCING LYMPHOCYTES AND REGULATING THE ACTIVITY THEREOFMay 2023January 2024Allow820NoNo
18316899VIRAL VECTORS FOR CANCER THERAPYMay 2023May 2025Allow2430YesNo
18008674ARTIFICIAL NON-CODING RNA MODULE FOR ENHANCING NITROGEN FIXATION ABILITY OF MICROORGANISMSDecember 2022January 2025Allow2520YesNo
17936023D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOFSeptember 2022June 2025Allow3300NoNo
17843916METHODS OF OBTAINING TUMOR-SPECIFIC T CELL RECEPTORSJune 2022May 2024Abandon2340NoNo
17540377Compositions and Methods for Treating Cancer with DuoCARsDecember 2021March 2025Allow3910YesNo
17498520ADMINISTRATION OF KYNURENINE DEPLETING ENZYMES FOR TUMOR THERAPYOctober 2021January 2025Abandon3910NoNo
17493032Antigen Binding Regions Against Fibronectin Type III Domains and Methods of Using the SameOctober 2021November 2024Allow3800YesNo
17386063FABRY DISEASE GENE THERAPYJuly 2021April 2025Allow4420NoNo
17337018COMPOSITIONS AND METHODS FOR TREATING CANCER WITH ANTI-BCMA IMMUNOTHERAPYJune 2021April 2025Allow4711YesNo
17331733Compositions and Methods for Treating Cancer with Anti-CD38 ImmunotherapyMay 2021March 2025Allow4511YesNo
17245952DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONSApril 2021December 2024Allow4410NoNo
17206878Intrathecal Delivery of Recombinant Adeno-Associated Virus 9March 2021September 2024Allow4220YesNo
17264911TAG72 TARGETED CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELLS FOR TREATMENT OF TAG72-POSITIVE TUMORSFebruary 2021December 2024Allow4610YesNo
17150858METHODS FOR GENERATING ANIMALS WITH DESIRABLE TRAITSJanuary 2021February 2025Allow4920NoNo
17139097COMPOSITIONS AND METHODS FOR TREATING DISEASESDecember 2020October 2024Abandon4620NoNo
17124922Chimeric Growth Factor ReceptorsDecember 2020June 2025Abandon5421YesNo
17253491POLYNUCLEOTIDEDecember 2020January 2025Abandon4930NoNo
15733815USES AND METHODS FOR ONCOLYTIC VIRUS TARGETING OF IL-4/IL-13 AND FUSIONS THEREOFNovember 2020April 2025Allow5330YesNo
17044085PRODUCTION OF BROWN ADIPOCYTESSeptember 2020June 2024Allow4420YesNo
17040009CHIMERIC TRANSMEMBRANE PROTEINS AND USES THEREOFSeptember 2020December 2024Allow5121NoNo
17018088NON-CODING IMMUNOMODULATORY DNA CONSTRUCTSeptember 2020October 2024Abandon4920NoNo
17008086ARTIFICIAL ANTIGEN PRESENTING CELLS HAVING A DEFINED AND DYNAMIC SHAPEAugust 2020June 2025Abandon5830NoNo
16989307ALIGNED FIBER AND METHOD OF USE THEREOFAugust 2020August 2024Allow4820YesNo
16968602METHODS FOR SCREENING VARIANT OF TARGET GENEAugust 2020January 2025Allow5320YesNo
16943335Altering Gene Expression in CART Cells and Uses ThereofJuly 2020February 2025Allow5531YesNo
16965895USE OF LENTIVIRAL VECTORS EXPRESSING FACTOR VIIIJuly 2020March 2025Allow5520NoNo
16923606Electroporation Devices And Methods Of Cell TransfectionJuly 2020July 2024Allow4931YesNo
16921783COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTIONJuly 2020May 2025Abandon5940NoNo
16880402Controlled Transgene Expression in Regulatory T CellsMay 2020May 2024Allow4841YesYes
16807254Collection, Genome Editing, And Washing Of T-Cell LymphocytesMarch 2020August 2024Allow5330YesNo
16610883GENE THERAPY FOR CILIOPATHIESNovember 2019July 2024Allow5641YesNo
16498369SHRNA EXPRESSION CASSETTE, POLYNUCLEOTIDE SEQUENCE CARRYING SAME, AND APPLICATION THEREOFSeptember 2019December 2024Abandon6051NoNo
16537192NUCLEIC ACID MOLECULES AND USES THEREOF FOR NON-VIRAL GENE THERAPYAugust 2019July 2024Allow5941YesYes
16502859MICROFLUIDIC DEVICES, SYSTEMS, INFRASTRUCTURES, USES THEREOF AND METHODS FOR GENETIC ENGINEERING USING SAMEJuly 2019March 2025Abandon6031NoNo
16409406COMPOSITIONS FOR THE INACTIVATION OF VIRUS REPLICATION AND METHODS OF MAKING AND USING THE SAMEMay 2019May 2025Abandon6040YesNo
16405285ONCOLYTIC ADENOVIRUSES FOR TREATING CANCERMay 2019June 2024Allow6051YesNo
16326126METHODS AND COMPOSITIONS FOR TARGETED GENE TRANSFERFebruary 2019February 2025Abandon6061YesNo
16318965COMPOSITIONS AND METHODS FOR STUDYING THE TAT GENEJanuary 2019April 2025Allow6040YesNo
16060651HUMAN T CELL DERIVED FROM T CELL-DERIVED INDUCED PLURIPOTENT STEM CELL AND METHODS OF MAKING AND USINGJune 2018December 2024Allow6091YesNo
15773779NUCLEIC ACIDS, PEPTIDES AND METHODSMay 2018April 2025Allow6052YesNo
15571460COMPOSITIONS COMPRISING MESENCHYMAL STEM CELLS AND USES THEREOFNovember 2017December 2024Abandon6071YesYes
15533983A Method for Producing a Recombinant Allotypespecific Rabbit Monoclonal AntibodyJune 2017November 2024Allow6051YesYes
15144637Oncolytic Adenoviruses for Cancer TreatmentMay 2016March 2018Allow2210NoNo
15137134METHODS OF DNA CONSTRUCTS FOR HIGH YIELD PRODUCTION OF POLYPEPTIDESApril 2016December 2017Allow1910NoNo
15136726HYBRID CAULIMOVIRUS PROMOTERS AND CONSTRUCTS THEREOFApril 2016August 2017Allow1620YesNo
14216907MODULATION OF MEIOTIC RECOMBINATIONMarch 2014October 2015Allow1920NoNo
14073979Simian Adenovirus Nucleic Acid and Amino Acid Sequences, Vectors Containing Same, and Methods of UseNovember 2013May 2015Allow1811NoNo
13968757Simian Subfamily B Adenoviruses SAdV-28, -27, -29, -32, -33, and -35 and Uses ThereofAugust 2013July 2015Allow2311NoNo
13930345CHIMERIC PROMOTERS CAPABLE OF MEDIATING GENE EXPRESSION IN PLANTS UPON PATHOGEN INFECTION AND USES THEREOFJune 2013December 2015Allow2921YesNo
13930387CHIMERIC PROMOTERS CAPABLE OF MEDIATING GENE EXPRESSION IN PLANTS UPON PATHOGEN INFECTION AND USES THEREOFJune 2013April 2016Allow3431NoNo
13930266CHIMERIC PROMOTERS CAPABLE OF MEDIATING GENE EXPRESSION IN PLANTS UPON PATHOGEN INFECTION AND USES THEREOFJune 2013December 2015Allow2921YesNo
13930663Methods For Increasing Homologous Recombination Of A Nucleic Acid SequenceJune 2013June 2014Allow1220NoNo
13930307CHIMERIC PROMOTERS CAPABLE OF MEDIATING GENE EXPRESSION IN PLANTS UPON PATHOGEN INFECTION AND USES THEREOFJune 2013January 2017Allow4241NoNo
13751819DUPLEXED PARVOVIRUS VECTORSJanuary 2013March 2014Allow1310NoNo
13729961USE OF A GRANULIN OR A GRANULIN-LIKE COMPOUND FOR THE THERAPY OR PROPHYLAXIS OF CHRONIC PAINDecember 2012January 2017Allow4940YesYes
13710007METHODS FOR INCREASING HOMOLOGOUS RECOMBINATION OF A NUCLEIC ACID SEQUENCEDecember 2012February 2013Allow200NoNo
13688864METHODS OF INHIBITING GROWTH OF A NEOPLASTIC CELLNovember 2012April 2016Allow4121YesNo
13434694METHODS FOR INCREASING HOMOLOGOUS RECOMBINATION OF A NUCLEIC ACID SEQUENCEMarch 2012August 2012Allow500YesNo
13419189Transducible Polypeptides For Modifying MetabolismMarch 2012August 2014Allow2920NoNo
13399434NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDES TO TARGET TISSUEFebruary 2012September 2014Allow3130NoNo
13296878FACTOR TAKING PART IN TRANSCRIPTION CONTROLNovember 2011July 2014Allow3230YesNo
13225509CHIMERIC PROMOTERS CAPABLE OF MEDIATING GENE EXPRESSION IN PLANTS UPON PATHOGEN INFECTION AND USES THEREOFSeptember 2011July 2013Allow2210NoNo
13112705METHODS AND COMPOSITIONS FOR DELIVERING POLYNUCLEOTIDESAugust 2011May 2013Allow2420NoYes
13171751NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDES TO PLANTSJune 2011February 2013Allow2011NoNo
13122339HCV ENTRY FACTOR, OCCLUDINJune 2011October 2014Allow4221YesNo
12597891PROMOTER INDUCIBLE BY REACTIVE OXYGEN SPECIES AND VECTOR COMPRISING THE SAMEJune 2010May 2013Allow4311YesNo
12817851Modified Viral Vector ParticlesJune 2010December 2013Allow4221NoNo
12518967TOL1 FACTOR TRANSPOSASE AND DNA INTRODUCTION SYSTEM USING THE SAMEJanuary 2010June 2013Allow4811NoNo
11913106ANTIVIRAL RESISTANCE MUTANTS AND APPLICATIONS THEREOFMay 2008January 2013Abandon6081YesYes
12049862METHODS FOR ISOLATING AND CHARACTERIZING ENDOGENOUS MRNA-PROTEIN (MRNP) COMPLEXESMarch 2008November 2011Allow4420YesNo
11963207VARIANTS OF ALPHA-FETOPROTEIN CODING AND EXPRESSION SEQUENCESDecember 2007November 2011Allow4711NoNo
11932674NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDES TO TARGET TISSUEOctober 2007December 2011Allow4921NoNo
11930892NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDES TO PLANTSOctober 2007July 2011Allow4420YesNo
11977787COMPOSITIONS AND METHODS FOR ENHANCED EXPRESSION OF RECOMBINANT POLYPEPTIDES FROM A SINGLE VECTOR USING A PEPTIDE CLEAVAGE SITEOctober 2007September 2009Allow2310YesNo
11854273Compositions and Methods for Regulating Peptidyltransferase Activity and Uses ThereofSeptember 2007July 2015Allow6021YesYes
11820439SIMIAN ADENOVIRUS NUCLEIC ACID AND AMINO ACID SEQUENCES, VECTORS CONTAINING SAME, AND METHODS OF USEJune 2007September 2011Allow5122NoNo
11542590ARTIFICIAL BIDIRECTIONAL PROMOTER FOR ACTIVATION OF GENE EXPRESSIONOctober 2006April 2008Allow1820NoNo
10567661CHIMAERIC VECTOR SYSTEMSeptember 2006June 2012Allow6051NoNo
11512563RHOB AS A SUPPRESSOR OF CANCER CELL GROWTH, CELL TRANSFORMATION, AND METASTASISAugust 2006August 2009Allow3521YesNo
11453658ENHANCED MEDIATED DNA TRANSFERJune 2006February 2010Allow4442NoNo
11442504TARGETED RETROGRADE GENE DELIVERY TO MOTOR NEURONSMay 2006October 2009Allow4120YesNo
10559583Archaeon expression systemMay 2006November 2013Allow6050YesNo
11389432NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDESMarch 2006June 2012Abandon6041YesYes
10571779METHOD FOR DETECTING MUTATION AND A METHOD FOR INDUCING MUTATIONMarch 2006August 2009Allow4121NoNo
11023020DIRECTED APOPTOSIS IN COX-2 OVEREXPRESSING CANCER CELLS THROUGH EXPRESSION TARGETED GENE DELIVERYDecember 2004August 2009Allow5531NoNo
11003941Methods of unidirectional, site-specific integration into a genome, compositions and kits for practicing the sameDecember 2004January 2013Allow6041YesYes
10999171METHODS FOR TARGETING RNA MOLECULESNovember 2004April 2010Abandon6061NoNo
10984406Regulatory sequences that direct gene expression to spinal motor neurons and uses thereofNovember 2004May 2013Allow6061YesYes
10972963METHODS AND COMPOSITIONS FOR DELIVERING POLYNUCLEOTIDESOctober 2004May 2011Allow6061YesNo
10489221CREATION OF ARTIFICIAL INTERNAL RIBOSOME ENTRY SITE (IRES) ELEMENTSOctober 2004February 2012Allow6041YesNo
10928815Rapid way to obtain high expression clones of mammalian cells using a methylcellulose and immunoprecipitation screening methodAugust 2004April 2015Allow6061YesYes

Appeals Overview

This analysis examines appeal outcomes and the strategic value of filing appeals for examiner MARVICH, MARIA.

Patent Trial and Appeal Board (PTAB) Decisions

Total PTAB Decisions
4
Examiner Affirmed
0
(0.0%)
Examiner Reversed
4
(100.0%)
Reversal Percentile
91.3%
Higher than average

What This Means

With a 100.0% reversal rate, the PTAB has reversed the examiner's rejections more often than affirming them. This reversal rate is in the top 25% across the USPTO, indicating that appeals are more successful here than in most other areas.

Strategic Value of Filing an Appeal

Total Appeal Filings
34
Allowed After Appeal Filing
10
(29.4%)
Not Allowed After Appeal Filing
24
(70.6%)
Filing Benefit Percentile
41.1%
Lower than average

Understanding Appeal Filing Strategy

Filing a Notice of Appeal can sometimes lead to allowance even before the appeal is fully briefed or decided by the PTAB. This occurs when the examiner or their supervisor reconsiders the rejection during the mandatory appeal conference (MPEP § 1207.01) after the appeal is filed.

In this dataset, 29.4% of applications that filed an appeal were subsequently allowed. This appeal filing benefit rate is below the USPTO average, suggesting that filing an appeal has limited effectiveness in prompting favorable reconsideration.

Strategic Recommendations

Appeals to PTAB show good success rates. If you have a strong case on the merits, consider fully prosecuting the appeal to a Board decision.

Filing a Notice of Appeal shows limited benefit. Consider other strategies like interviews or amendments before appealing.

Examiner MARVICH, MARIA - Prosecution Strategy Guide

Executive Summary

Examiner MARVICH, MARIA works in Art Unit 1634 and has examined 142 patent applications in our dataset. With an allowance rate of 85.9%, this examiner has an above-average tendency to allow applications. Applications typically reach final disposition in approximately 49 months.

Allowance Patterns

Examiner MARVICH, MARIA's allowance rate of 85.9% places them in the 58% percentile among all USPTO examiners. This examiner has an above-average tendency to allow applications.

Office Action Patterns

On average, applications examined by MARVICH, MARIA receive 3.38 office actions before reaching final disposition. This places the examiner in the 99% percentile for office actions issued. This examiner issues more office actions than most examiners, which may indicate thorough examination or difficulty in reaching agreement with applicants.

Prosecution Timeline

The median time to disposition (half-life) for applications examined by MARVICH, MARIA is 49 months. This places the examiner in the 1% percentile for prosecution speed. Applications take longer to reach final disposition with this examiner compared to most others.

Interview Effectiveness

Conducting an examiner interview provides a +6.5% benefit to allowance rate for applications examined by MARVICH, MARIA. This interview benefit is in the 34% percentile among all examiners. Recommendation: Interviews provide a below-average benefit with this examiner.

Request for Continued Examination (RCE) Effectiveness

When applicants file an RCE with this examiner, 21.5% of applications are subsequently allowed. This success rate is in the 17% percentile among all examiners. Strategic Insight: RCEs show lower effectiveness with this examiner compared to others. Consider whether a continuation application might be more strategic, especially if you need to add new matter or significantly broaden claims.

After-Final Amendment Practice

This examiner enters after-final amendments leading to allowance in 45.9% of cases where such amendments are filed. This entry rate is in the 64% percentile among all examiners. Strategic Recommendation: This examiner shows above-average receptiveness to after-final amendments. If your amendments clearly overcome the rejections and do not raise new issues, consider filing after-final amendments before resorting to an RCE.

Appeal Withdrawal and Reconsideration

This examiner withdraws rejections or reopens prosecution in 87.5% of appeals filed. This is in the 78% percentile among all examiners. Of these withdrawals, 82.1% occur early in the appeal process (after Notice of Appeal but before Appeal Brief). Strategic Insight: This examiner frequently reconsiders rejections during the appeal process compared to other examiners. Per MPEP § 1207.01, all appeals must go through a mandatory appeal conference. Filing a Notice of Appeal may prompt favorable reconsideration even before you file an Appeal Brief.

Petition Practice

When applicants file petitions regarding this examiner's actions, 50.0% are granted (fully or in part). This grant rate is in the 59% percentile among all examiners. Strategic Note: Petitions show above-average success regarding this examiner's actions. Petitionable matters include restriction requirements (MPEP § 1002.02(c)(2)) and various procedural issues.

Examiner Cooperation and Flexibility

Examiner's Amendments: This examiner makes examiner's amendments in 28.9% of allowed cases (in the 100% percentile). Per MPEP § 1302.04, examiner's amendments are used to place applications in condition for allowance when only minor changes are needed. This examiner frequently uses this tool compared to other examiners, indicating a cooperative approach to getting applications allowed. Strategic Insight: If you are close to allowance but minor claim amendments are needed, this examiner may be willing to make an examiner's amendment rather than requiring another round of prosecution.

Quayle Actions: This examiner issues Ex Parte Quayle actions in 11.5% of allowed cases (in the 89% percentile). Per MPEP § 714.14, a Quayle action indicates that all claims are allowable but formal matters remain. This examiner frequently uses Quayle actions compared to other examiners, which is a positive indicator that once substantive issues are resolved, allowance follows quickly.

Prosecution Strategy Recommendations

Based on the statistical analysis of this examiner's prosecution patterns, here are tailored strategic recommendations:

  • Expect multiple rounds of prosecution: This examiner issues more office actions than average. Address potential issues proactively in your initial response and consider requesting an interview early in prosecution.
  • Appeal filing as negotiation tool: This examiner frequently reconsiders rejections during the appeal process. Filing a Notice of Appeal may prompt favorable reconsideration during the mandatory appeal conference.
  • Plan for extended prosecution: Applications take longer than average with this examiner. Factor this into your continuation strategy and client communications.
  • Examiner cooperation: This examiner frequently makes examiner's amendments to place applications in condition for allowance. If you are close to allowance, the examiner may help finalize the claims.

Relevant MPEP Sections for Prosecution Strategy

  • MPEP § 713.10: Examiner interviews - available before Notice of Allowance or transfer to PTAB
  • MPEP § 714.12: After-final amendments - may be entered "under justifiable circumstances"
  • MPEP § 1002.02(c): Petitionable matters to Technology Center Director
  • MPEP § 1004: Actions requiring primary examiner signature (allowances, final rejections, examiner's answers)
  • MPEP § 1207.01: Appeal conferences - mandatory for all appeals
  • MPEP § 1214.07: Reopening prosecution after appeal

Important Disclaimer

Not Legal Advice: The information provided in this report is for informational purposes only and does not constitute legal advice. You should consult with a qualified patent attorney or agent for advice specific to your situation.

No Guarantees: We do not provide any guarantees as to the accuracy, completeness, or timeliness of the statistics presented above. Patent prosecution statistics are derived from publicly available USPTO data and are subject to data quality limitations, processing errors, and changes in USPTO practices over time.

Limitation of Liability: Under no circumstances will IronCrow AI be liable for any outcome, decision, or action resulting from your reliance on the statistics, analysis, or recommendations presented in this report. Past prosecution patterns do not guarantee future results.

Use at Your Own Risk: While we strive to provide accurate and useful prosecution statistics, you should independently verify any information that is material to your prosecution strategy and use your professional judgment in all patent prosecution matters.